Acidomonas methanolica-associated necrotizing lymphadenitis in a patient with chronic granulomatous disease.

abstract：:Thymomas can present with a variety of paraneoplastic manifestations, mostly of autoimmune origin, including Good's syndrome when there is associated hypogammaglobulinemia. Although pure red cell aplasia is a recognised complication of thymoma, selective white cell aplasia is very rare, particularly in Good's syndrome...

journal_title：Journal of clinical immunology

authors： Akinosoglou K,Melachrinou M,Siagris D,Koletsis E,Marangos M,Gogos CA,Solomou EE

更新日期：2014-04-01 00:00:00

abstract：:Chemotherapeutic agent is characterized by its concentration in tumor cells with minimum side effects. Oleandrin, a polyphenolic cardiac glycoside is known to induce apoptosis in tumor cells. However, no report is available on its efficacy in primary cells. In this report we are providing the evidence that oleandrin i...

journal_title：Journal of clinical immunology

authors： Sreenivasan Y,Raghavendra PB,Manna SK

更新日期：2006-07-01 00:00:00

abstract：:The biological differences between lymphocytes separated from thymoma patients with myasthenia gravis (MG) and those separated from thymoma patients without MG was examined. We investigated whether lymphocytes in thymoma (Th-L) of patients with and without MG could react to interleukin-2 (IL-2) to develop cytolytic ac...

journal_title：Journal of clinical immunology

authors： Takahashi K,Monden Y,Saito S,Kamamura Y,Uyama T

更新日期：1996-07-01 00:00:00

abstract：:To study the mechanisms of hepatocyte injury, we examined serum interleukin-6 (IL-6) level in acute hepatitis patients. Based on their clinical features, these patients were divided into three groups, acute hepatitis (AH), severe acute hepatitis, and fulminant hepatic failure (FHF). The present study demonstrated that...

journal_title：Journal of clinical immunology

authors： Sun Y,Tokushige K,Isono E,Yamauchi K,Obata H

更新日期：1992-05-01 00:00:00

abstract：:Murine B16 melanoma cell line is poorly immunogenic and highly aggressive. We recently reported that the transmembrane staphylococcal enterotoxin A (TM-SEA) anchors onto B16 cells and stimulates lymphocyte proliferation. The purpose of the study was to investigate whether vaccination with B16 cells bearing membrane-an...

journal_title：Journal of clinical immunology

authors： Ma W,Yu H,Wang Q,Jin H,Solheim J,Labhasetwar V

更新日期：2004-05-01 00:00:00

abstract：PURPOSE:Inherited defects in the adenosine deaminase (ADA) enzyme can cause severe combined immune deficiency (SCID) and systemic abnormalities. Management options for ADA-deficient patients include enzyme replacement therapy (ERT), hematopoietic stem cell transplantation (HSCT), and gene therapy (GT). Here, we describ...

journal_title：Journal of clinical immunology

authors： Scott O,Kim VH,Reid B,Pham-Huy A,Atkinson AR,Aiuti A,Grunebaum E

更新日期：2017-08-01 00:00:00

abstract：:We studied immunological functions of peripheral blood lymphocytes (PBL) from human T-cell leukemia virus type I (HTLV-I)-seropositive healthy carriers in vitro. Proliferative responses of PBL to T-cell and B-cell mitogens such as concanavalin A (Con A), pokeweed mitogen (PWM), and Staphylococcus aureus Cowan I (SAC) ...

journal_title：Journal of clinical immunology

authors： Tanaka Y,Oda S,Nagata K,Mori N,Sakamoto H,Eto S,Yamashita U

更新日期：1989-11-01 00:00:00

abstract：:In this retrospective study 103 serum samples from 16 females with systemic lupus erythematosus (SLE), obtained during a mean follow-up time of 2 years, were investigated for the presence of anti-denatured [single-stranded (ss)] DNA antibodies of the IgG, IgM, and IgA classes. The anti-ssDNA antibodies were determined...

journal_title：Journal of clinical immunology

authors： Gripenberg M,Leirisalo M,Johansson E,Gripenberg G

更新日期：1985-09-01 00:00:00

abstract：:Oral tolerance is the immunologic mechanism by which the mucosal immune system maintains unresponsiveness to the myriad of antigens in the mucosal environment which might otherwise induce untoward immune responses. Recent studies have shown that it is mediated by several distinct, yet interacting mechanisms including ...

journal_title：Journal of clinical immunology

authors： Strober W,Kelsall B,Marth T

更新日期：1998-01-01 00:00:00

abstract：:Adoptive immunotherapy with in vitro expanded cytotoxic T lymphocytes specific for Epstein-Barr virus (EBV) can successfully treat post-transplant lymphoproliferative disease (PTLD). However, extension of a similar strategy to Hodgkin's disease (HD) and nasopharyngeal carcinoma (NPC) is limited by the poor immunogenic...

journal_title：Journal of clinical immunology

authors： Jurgens LA,Khanna R,Weber J,Orentas RJ

更新日期：2006-01-01 00:00:00

abstract：:Common variable immune deficiency (CVID) B cells have impaired responses to TLR7 and TLR9 agonists including poor cell proliferation, loss of cytokine production, and failure to produce IgG or IgA. We show that TLR7- or 9-activated B cells from CVID subjects with >0.5% peripheral isotype-switched CD27(+) B cells (grou...

journal_title：Journal of clinical immunology

authors： Yu JE,Zhang L,Radigan L,Sanchez-Ramon S,Cunningham-Rundles C

更新日期：2012-02-01 00:00:00

abstract：INTRODUCTION:Treating recipient mice with palifermin (recombinant human keratinocyte growth factor) prevents the development of acute, lethal, graft-versus-host disease (GVHD). This is due, at least in part, to the ability of palifermin to protect epithelial cells from injury. Using the C57BL/6-->(C57BL/6 x DBA/2)F(1)-...

journal_title：Journal of clinical immunology

authors： Ellison CA,Makar BM,Wiseman JM,Gheorghiu I,Taniguchi M,Gartner JG

更新日期：2008-09-01 00:00:00

abstract：:Activated PI3K δ syndrome (APDS) is a primary immunodeficiency caused by heterogeneous germline gain-of-function mutations which ultimately lead to the hyperactivation of the phosphoinositide-3-kinase δ (PI3K δ). PI3K δ exists as a heterodimer composed of a catalytic and a regulatory subunit. APDS type 2 is caused by ...

journal_title：Journal of clinical immunology

authors： Ramirez L,Tamayo W,Ale H

更新日期：2020-10-01 00:00:00

abstract：:The basis of the immunological unresponsiveness seen in leprosy patients is unknown. Untreated lepromatous leprosy patients display an unspecific cellular anergy which disappears with treatment, leaving an anergy specific for Mycobacterium leprae. These patients suffer from a complication, erythema nodosum leprosum, c...

journal_title：Journal of clinical immunology

authors： Mshana RN,Haregewoin A,Belehu A

更新日期：1982-04-01 00:00:00

abstract：:A molecular analysis of complement components (C3, C4, and factor B) in human saliva was performed by SDS-PAGE and immunoblotting. Complement C3 was detected as a molecule composed of a 115-kDa alpha-chain linked to a 70-kDa beta chain by disulfide bonds, and C3 levels ranged from 0.52 to 15.0 micrograms/ml (n = 15). ...

journal_title：Journal of clinical immunology

authors： Andoh A,Fujiyama Y,Kimura T,Uchihara H,Sakumoto H,Okabe H,Bamba T

更新日期：1997-09-01 00:00:00

abstract：PURPOSE:To assess the serum profile of factors involved in endothelial, T-cell, and fibroblast interplay in patients with Raynaud's phenomenon (RP) associated with nailfold vodeocapillaroscopy (NVC) scleroderma findings and/or systemic sclerosis (SSc) marker autoantibodies, recently labeled as early SSc patients. METH...

journal_title：Journal of clinical immunology

authors： Vettori S,Cuomo G,Iudici M,D'Abrosca V,Giacco V,Barra G,De Palma R,Valentini G

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:Survival of the Leishmania parasite within monocytes hinges on its ability to effectively nullify their microbicidal effector mechanisms. Accordingly, this study aimed to delineate this biological niche in patients with visceral leishmaniasis (VL). METHODS:In monocytes, the redox status, antigen presenting cap...

journal_title：Journal of clinical immunology

authors： Roy S,Mukhopadhyay D,Mukherjee S,Ghosh S,Kumar S,Sarkar K,Pal D,Bhowmik P,Mandal K,Modak D,Guha SK,Pramanik N,Goswami RP,Saha B,Chatterjee M

更新日期：2015-01-01 00:00:00

abstract：:Human papillomavirus (HPV) infects the transformation zone of the cervix and is the primary cause of cervical cancer. The infection is localized to the cervix and mucosal immunity is likely to be an important determinant for viral clearance. Previous studies of immunity to HPV have measured immune markers in the blood...

journal_title：Journal of clinical immunology

authors： Castle PE,Hildesheim A,Bowman FP,Strickler HD,Walker JL,Pustilnik T,Edwards RP,Crowley-Nowick PA

更新日期：2002-01-01 00:00:00

abstract：:Cytotoxic lymphocytes are critical in the control of HIV replication, it has been shown that perforin is the key effector of killing machinery for CTLs and NK cells, so we investigated the circulating levels of perforin in CD8+ T cells and NK cells by flow cytometry intracellular stain in Chinese HIV infected individu...

journal_title：Journal of clinical immunology

authors： Qi W,Yongjun J,Yanan W,Zining Z,Xiaoxu H,Jing L,Hong S

更新日期：2006-07-01 00:00:00

abstract：:The use of exogenous serum to provide protection against infections began more than a century ago. Over time, this concept matured and led to the preparation of concentrated immunoglobulin (IgG) products that were safe and effective when delivered subcutaneously (SC) or intramuscularly (IM) but were not ideal for intr...

journal_title：Journal of clinical immunology

authors： Torgerson TR

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:The molecular and cellular interactions between the immune system and bone tissue have been established. Sex hormone deficiency after menopause has multifunctional role by influencing growth, differentiation, and metabolism of the skeletal and the immune system. DISCUSSION:We have used nonparametric and m...

journal_title：Journal of clinical immunology

authors： Kósa JP,Balla B,Kiss J,Podani J,Takács I,Lazáry A,Nagy Z,Bácsi K,Karsai A,Speer G,Lakatos P

更新日期：2009-11-01 00:00:00

abstract：:The immune response of 56 colorectal cancer patients to a single infusion of 1 mg of radiolabeled (111In) mouse B72.3-GYK-DTPA immunoconjugate was examined using a double-antigen radiometric assay system. The incidence of antibody response was 48% to polyclonal mouse IgG, 71% to mouse B72.3, and 62% to chimeric B72.3....

journal_title：Journal of clinical immunology

authors： Khazaeli MB,Saleh MN,Liu T,Kaladas PM,Gilman SC,LoBuglio AF

更新日期：1992-03-01 00:00:00

abstract：:CFSE dye dilution analysis and [3H] thymidine incorporation were used side by side to assess proliferative responses of peripheral blood mononuclear cells (PBMCs) after vaccination of renal cell carcinoma patients (n=6) with antigen-loaded dendritic cells. Immune responses against the control antigen keyhole limpet he...

journal_title：Journal of clinical immunology

authors： Putz T,Ramoner R,Gander H,Rahm A,Bartsch G,Höltl L,Thurnher M

更新日期：2004-11-01 00:00:00

abstract：:Antibodies to certain self-antigens are detected in normal individuals as well as in patients with autoimmune diseases. Natural autoantibodies found in normal human sera are thought to act as an immune regulator, a functional controller of specific proteins, or the first-line defense against pathogenic microorganisms....

journal_title：Journal of clinical immunology

authors： Suk K,Hwang DY,Lee MS

更新日期：1999-05-01 00:00:00

abstract：PURPOSE:Complete DiGeorge syndrome (cDGS) describes a subset of patients with DiGeorge syndrome that have thymic aplasia, and thus are at risk for severe opportunistic infections. Patients with cDGS and mycobacterial infection have not previously been described. We present this case to illustrate that patients with cDG...

journal_title：Journal of clinical immunology

authors： Yin SM,Ferdman RM,Wang L,Markert ML,Tam JS

更新日期：2015-07-01 00:00:00

abstract：:Common variable immunodeficiency (CVID) is a heterogeneous group of disorders, characterized by hypogammaglobulinemia and increased susceptibility to recurrent pyogenic infections, autoimmunity, and malignancies. Twenty-five cases with CVID (18 male and 7 female) and 25 healthy volunteers were investigate in this stud...

journal_title：Journal of clinical immunology

authors： Rezaei N,Haji-Molla-Hoseini M,Aghamohammadi A,Pourfathollah AA,Moghtadaie M,Pourpak Z

更新日期：2008-01-01 00:00:00

abstract：:Hypogammaglobulinemia is a common symptom in different immunodeficiencies. It is, however, not usually associated with Epstein-Barr virus (EBV) infections. The X-linked lymphoproliferative disease (XLP) on the other hand shows immunological changes in response to the EBV. Here we report three previously healthy boys, ...

journal_title：Journal of clinical immunology

authors： Hügle B,Suchowerskyj P,Hellebrand H,Adler B,Borte M,Sack U,Overberg-Schmidt US,Strnad N,Otto J,Meindl A,Schuster V

更新日期：2004-09-01 00:00:00

abstract：:We have undertaken an immunofluorescent analysis of the immunoglobulin heavy and light chains expressed by pre-B cells from normal human fetal and adult bone marrow using purified mouse monoclonal and goat antibodies to human immunoglobulin isotypes. Our results indicate that (i) the great majority of normal pre-B cel...

journal_title：Journal of clinical immunology

authors： Kubagawa H,Gathings WE,Levitt D,Kearney JF,Cooper MD

更新日期：1982-10-01 00:00:00

abstract：:Lymphocytes expressing gammadelta T cell receptors (TCR) constitute an entire system of functionally specialized subsets that have been implicated in the regulation of immune responses, including responses to pathogens and allergens, and in tissue repair. The gammadelta TCRs share structural features with adaptive rec...

journal_title：Journal of clinical immunology

authors： Born WK,Jin N,Aydintug MK,Wands JM,French JD,Roark CL,O'Brien RL

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:This study was done to further reveal the role of the innate immune system in celiac disease. METHODS:Dendritic cells were matured from venous blood of patients with active or treated celiac disease and DQ2-DQ8-positive or negative controls. Dendritic cells were treated with a peptic-tryptic digest of gli...

journal_title：Journal of clinical immunology

authors： Rakhimova M,Esslinger B,Schulze-Krebs A,Hahn EG,Schuppan D,Dieterich W

更新日期：2009-01-01 00:00:00