Abstract:
AIM:The aim of our study is to introduce a new objective method of perioperative evaluation of the size of diaphragmatic defect to enable comparison of results among various centres and methods used for diaphragmatic reconstruction. MATERIALS AND METHODS:Prospective observational study of neonates with congenital diaphragmatic hernia (CDH) and respiratory distress within 24 h of birth operated on from January 2009 to December 2011. Weight, length, thoracic shape and the diameters of diaphragmatic defect were measured. To determine the relative size of the defect, a defect-diaphragmatic ratio (DDR = defect area:diaphragm area × 100) was calculated. The measured and calculated data were subsequently compared between Gore-Tex patch group (GT) and primary repair group (PR). Mann-Whitney U test was used for statistical analysis. RESULTS:Forty-seven patients with CDH were admitted during study period. The overall survival rate was 79 % (37/47). Preoperative stabilization was achieved in 85 % (40/47). Survival of operated neonates was 93 % (37/40). Diaphragmatic reconstruction with Gore-Tex patch was used in 7 neonates (17 %), and primary repair in 33 (83 %). Mortality in Gore-Tex group was 29 %; mortality in primary repair group was 3 %. Data of anthropometric measurement were complete in 34 children (5 GT and 29 PR). Significant differences were found between GT group and PR group in the size of diaphragmatic defect with the transverse and sagittal diameters of defect (48.0 ± 5.7 vs. 30.1 ± 5.9, P < 0.00061; 34.0 ± 12.5 vs. 16.0 ± 7.3, P < 0.0022) and DDR (18.29 ± 4.60 vs. 5.77 ± 3.28, P < 0.0005), respectively. CONCLUSION:The value of DDR as an objective criterion of the extent of diaphragmatic defect was confirmed by the close correlation between DDR and feasibility of primary repair in the study group. This objective assessment of defect size may improve comparing various surgical techniques and results of different centres, and thus facilitates sharing experience with management of neonates with CDH.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Rygl M,Kuklova P,Zemkova D,Slaby K,Pycha K,Stranak Z,Melichar J,Snajdauf Jdoi
10.1007/s00383-012-3113-7subject
Has Abstractpub_date
2012-10-01 00:00:00pages
971-6issue
10eissn
0179-0358issn
1437-9813journal_volume
28pub_type
杂志文章abstract:PURPOSE:For International Neuroblastoma Staging System (INSS) stages III or IV neuroblastoma (intermediate or high risk), complete excision of the primary tumor is not always feasible. Most current studies on the treatment outcome of these patients have reported on the complete excision status. The aim of this study is...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2417-8
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:We investigated the relationship between the affected lobe and symptom onset in prenatally diagnosed congenital pulmonary airway malformation (CPAM). METHODS:53 CPAM patients diagnosed prenatally were reviewed retrospectively by creating 2 groups according to symptom onset. Group Sneo: (symptomatic during the ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-019-04460-x
更新日期:2019-05-01 00:00:00
abstract::Minimally invasive surgery (MIS) for cancer patients has become widely accepted in general surgery, however, it has not completely replaced the standard open operative procedures in pediatric oncology. The aim of this study was to evaluate the host relationship following MIS in a murine model of retroperitoneal neurob...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050271
更新日期:1998-03-01 00:00:00
abstract::The presacral cystic teratoma in an infant is reported. The cyst consisted solely of central nervous system tissue. This pathologic finding is extremely rare. A review of the literature reveals no previous report of a teratoma arising in this manner. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0831-2
更新日期:2002-12-01 00:00:00
abstract:INTRODUCTION:Hepatoportoenterostomy (HPE) with the Kasai procedure is the treatment of choice for biliary atresia (BA) as the initial surgery. However, the appropriate level of dissection level of the fibrous cone (FC) of the porta hepatis (PH) is frequently unclear, and the procedure sometimes results in unsuccessful ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3799-4
更新日期:2015-12-01 00:00:00
abstract::It is unknown whether noncomplicated acute appendicitis cause bacterial translocation. In this study, we aimed to test development of the bacterial translocation in the patients who were operated for acute appendicitis. In this prospective study, 10 control patients who underwent elective operations because of other r...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-1899-5
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:Retroperitoneal teratomas (RTs) are rare among germ cell tumors and predominantly occur in infants. RTs are often difficult to manage by perioperative management. In this study, we retrospectively reviewed our series of RTs. METHODS:Seventy patients with germ cell tumors were treated from 1989 to 2015 in our i...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3938-6
更新日期:2016-09-01 00:00:00
abstract:INTRODUCTION:Bladder Bowel Dysfunction (BBD) has been described in patients with Down's Syndrome (DS). Our aim was to report the incidence, demographics, presentation, complications and management of the bladder in DS patients with BBD. METHODS:A systematic review was performed using PRISMA guidelines and search terms...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04682-4
更新日期:2020-07-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2322-1
更新日期:2009-03-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0853-9
更新日期:2003-06-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-1957-z
更新日期:2008-04-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3575-x
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:Recognition of physical child abuse is imperative for ensuring children's safety. Screening tools (ST) may increase identification of physical abuse; however, the extent of their use is unknown. This study assessed use of STs for physical abuse in children's hospitals and determined attitudes regarding STs. ME...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3916-z
更新日期:2016-08-01 00:00:00
abstract::A reproducible technique was developed experimentally in pigs for construction of a 'composite bowel tube' (CBT) made up of ileal mucosa that was grafted to a mucosally denuded colonic muscle surface vascularised by the colonic mesentery. Macroscopic and microscopic studies at terminal laparotomy revealed a viable, mu...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00178430
更新日期:1996-04-01 00:00:00
abstract::This article describes five cases of congenital epulis, a rare and benign swelling in the mouth of a newborn, which is not widely known. We present five cases: four cases presented as single pedunculated nodules of the gingiva and in one case two nodules were present. Of all, 50% were located at the maxilla. Excision ...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-008-2304-8
更新日期:2009-02-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s003830000557
更新日期:2002-03-01 00:00:00
abstract:BACKGROUND:Vitamin D deficiency is associated with intestinal barrier dysfunction, which contributes to pathogenesis of acute intestinal injury in children. We aim to investigate the effects of vitamin D on intestinal injury in intestinal epithelial cells and organoids. METHODS:Lipopolysaccharide (LPS) was used to ind...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-019-04586-y
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Voltage-gated potassium ion channels have long been implicated in gastrointestinal motility. Recent studies have highlighted the role of voltage-gated channel subfamily G member 3 (KCNG3) and 4 (KCNG4) genes in the electrical functioning of interstitial cells of Cajal and PDGFRα+ cells of the mouse colon. We de...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4394-2
更新日期:2019-02-01 00:00:00
abstract::Children with pyometrocolpos due to distal vaginal atresia may present as acutely ill, with severe obstructive uropathy and septicemia. In such patients the clinical course is markedly improved by urgent drainage of the infected cystic mass, and a temporary drainage procedure is required to allow local findings of inf...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1323-3
更新日期:2005-03-01 00:00:00
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journal_title:Pediatric surgery international
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doi:10.1007/s00383-015-3664-5
更新日期:2015-03-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00383-008-2131-y
更新日期:2008-06-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050488
更新日期:1998-12-01 00:00:00
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journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04642-y
更新日期:2020-05-01 00:00:00
abstract::Interposing vascularized flaps between urethra and skin sutures is recommended in hypospadias surgery to decrease the rate of urethrocutaneous fistula. For this purpose nine patients with failed results after at least one hypospadias surgery and with insufficient foreskin were included in the study. Tubularized incise...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-0989-2
更新日期:2003-11-01 00:00:00
abstract::Recurrent or chronic abdominal pain can be a challenging problem when conventional diagnostic studies fail to identify the cause. It is estimated that up to one-third of children suffer from abdominal pain, and in this population recurrent pain can be even more challenging. Although recurrent right lower quadrant (RLQ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1632-1
更新日期:2006-03-01 00:00:00
abstract:INTRODUCTION:This review aims to (1) assess the breadth of pediatric orthopaedic research in low- and middle-income countries (LMICs) and (2) determine the impact of academic collaboration (an LMIC and a non-LMIC investigator) in published LMIC research. METHODS:Pediatric orthopaedic clinical studies conducted in LMIC...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-018-4412-4
更新日期:2019-03-01 00:00:00
abstract:INTRODUCTION:Management of oesophageal atresia (OA) and trachea-oesophageal fistula (TOF) in babies of low birth weight is challenging especially when associated with other anomalies. Birth weight of <1500 g has previously formed part of a classification system designed to predict outcome, alongside the cardiac status ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3851-4
更新日期:2016-06-01 00:00:00
abstract::Sixty-seven patients with resected Wilms' tumour>1.0 kg are reported. Surgery in this group is difficult, may result in the sacrifice of adjacent structures, and frequently upstages the patient. Mortality is related to tumour burden. Whilst there is little agreement on the therapeutic implications of failure to respon...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1678-8
更新日期:2006-05-01 00:00:00
abstract:PURPOSE:Feeding and systemic hypoxia are major stresses inducing necrotizing enterocolitis (NEC). This study aims to investigate the role of systemic hypoxia in NEC and its effect before and after feeding. METHODS:Neonatal mice were studied in three groups. Control (N = 9): breast feeding; NEC A (N = 8), gavage feedin...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3997-8
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:We evaluated the effectiveness of prophylactic mesenteric lymphatic ligation in preventing iatrogenic chylous fistulae in abdominal neuroblastoma surgery. METHOD:All patients who underwent resection of abdominal neuroblastoma between years 2002 and 2013 were included. A change in surgical strategy commenced fr...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3581-z
更新日期:2014-10-01 00:00:00