Abstract：
:The Thomsen-Friedenreich cryptantigen (TCA) is located on the surface of all red cells, but is concealed by a layer of neuraminic acid. When bacteria that produce neuraminidase disrupt this coating, the TCA can be exposed and activated. If blood products containing antibody to the TCA are subsequently administered, haemolysis can result. While the relationship between TCA and necrotising enterocolitis (NEC) is well described, the incidence of TCA activation in other forms of sepsis in surgical neonates is not known. In a prospective study, 117 patients admitted to the Surgical Neonatal Nursery were examined for evidence of TCA activation. Of the 117 babies, 69 were clinically non-septic and only 1 had weak TCA activation (1.4%). Forty-eight were clinically or bacteriologically septic; 8 of these demonstrated TCA activation (17%), 3 of whom died. Forty of the septic group showed no evidence of TCA activation although 27 grew organisms on culture; 17 in this group died. Two of the TCA-activated babies received unwashed red cells, and both haemolysed; 4 TCA-activated babies received washed red cells and none haemolysed. Although 1 of the well babies in this study demonstrated TCA activation, we would not recommend routine TCA testing on clinically well babies. We would, however, recommend routine testing in all clinically septic infants, as 17% showed signs of TCA activation in this study. We would also suggest the adoption of a selective transfusion policy in TCA-activated patients to avoid the risk of haemolysis. This may help to reduce unnecessary morbidity and mortality in a high-risk group of neonates.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Grant HW,Hadley GP,Adhikari M,Fernandes-Costa Fdoi
10.1007/s003830050488subject
Has Abstractpub_date
1998-12-01 00:00:00pages
204-7issue
3eissn
0179-0358issn
1437-9813journal_volume
14pub_type
杂志文章abstract：BACKGROUND:The role of thymectomy in the treatment of juvenile myasthenia gravis (JMG) is poorly defined. The objective of this systematic review was to evaluate the effect of thymectomy on survival, disease severity, and peri-operative complications for patients with JMG. METHODS:A search of MEDLINE, EMBASE, and the ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-017-4086-3
更新日期：2017-06-01 00:00:00
abstract：:Pullthrough procedures for Hirschsprung diseases typically have favorable results. However, some children experience long-term postoperative complications comprising stooling disorders, such as intermittent enterocolitis, severe stool retention, intestinal obstruction, as well as incontinence. Reoperative Hirschsprung...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-016-4045-4
更新日期：2017-04-01 00:00:00
abstract：:We present three cases of abdominal and abdomino-thoracic extra-lobar pulmonary sequestrations detected by antenatal ultrasound (US) over a 12-month period. In addition, we briefly refer to a case previously described. A cystic mass was demonstrated in the left upper abdomen of the fetus in all four cases, with two ex...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00183739
更新日期：1996-03-01 00:00:00
abstract：:This study describes a subset of patients with posterior urethral valves (PUV) who presented late in childhood. The objective was to identify factors that lead to back-pressure effects on the upper tracts, which persist in spite of adequate valve ablation in some patients, and seek factors that may preserve the upper ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050384
更新日期：1998-09-01 00:00:00
abstract：PURPOSE:The purpose of this study was to test the susceptibility of human hepatoblastoma and neuroblastoma cells to photodynamic diagnostics (PDD) and photodynamic therapy (PDT) using 5-aminolevulinic acid (5-ALA) as a photosensitizer. METHODS:Cell cultures of human hepatoblastoma (HuH6) and neuroblastoma (MHH-NB-11) ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-008-2275-9
更新日期：2008-12-01 00:00:00
abstract：:Around the 30th week of gestation, patients with gastroschisis (GS) develop chronic inflammatory reactions on the serosal surface of the eventrated loops of intestine that lead to severe hyperfibrinogenemia and hypercoagulability, particularly if they are born prematurely. This result was found on comparison of coagul...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00183729
更新日期：1996-03-01 00:00:00
abstract：:A new instrument for suction rectal biopsy in infants suspected of having Hirschsprung's disease is described that can be completely dismantled, physically cleaned, lubricated, and heat-sterilised. These attributes are new and are absolutely critical today. The instrument has been used in 60 patients (ca. 180 biopsies...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01194812
更新日期：1997-01-01 00:00:00
abstract：:Surgical repair of acquired tracheo-esophageal fistula may result in tracheal stenosis or esophageal stricture. We used fistula with esophageal cuff as flap to repair the tracheal defect. Esophageal repair was performed by rotating ends through 90° in opposite direction. This technique offers excellent repair in a sin...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3498-6
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:Variation exists in the diagnostic testing for gastroesophageal reflux (GER) in infants and in the application of surgical therapy. There has been an increase in antireflux surgery (ARS) since the development of laparoscopy but the outcomes in high-risk infants is unclear. This study examines the results of ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4281-x
更新日期：2018-07-01 00:00:00
abstract：:Infected intra-abdominal cystic lymphangiomas are very rare. We report a case of a purulent mesenteric cyst, histologically a cystic lymphangioma, w which developed in a 1-year-old girl who presented with marked abdominal distension and high fever. Magnetic resonance imaging revealed that the huge cystic lesion occupi...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00174584
更新日期：1996-12-01 00:00:00
abstract：PURPOSE:Since 1999, complete primary repair of exstrophy has represented a valid alternative in the treatment of exstrophy patients, offering one- stage reconstruction for all components of this malformation in newborns. The vast majority of cases are currently approached within 48/72 h of life, and risk of vascular in...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-010-2745-8
更新日期：2011-04-01 00:00:00
abstract：:Congenital pyloric atresia (CPA) is a very rare condition that was first described by Calder in 1749. Commonly, CPA occurs as an isolated lesion, which has an excellent prognosis, but it can also be seen in association with other malformations, which can have a negative impact on the final outcome. The medical records...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1903-0
更新日期：2007-06-01 00:00:00
abstract：:A total of 235 children, aged between 7 months and 15 years had bronchoscopy on suspicion of foreign body aspiration. The histories of these patients were studied to examine the diagnostic value of symptoms, signs, and chest x-rays, and rate of negative bronchoscopy. The sensitivity of choking and coughing was high (8...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-003-0965-x
更新日期：2003-08-01 00:00:00
abstract：:The occurrence of a coexisting congenital diaphragmatic hernia (CDH) and esophageal atresia (EA) with distal tracheoesophageal fistula is extremely rare and is considered highly lethal. Only 19 cases of CDH with EA have been reported in the world literature to date. This is a very challenging clinical problem, and the...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s003830050448
更新日期：1998-11-01 00:00:00
abstract：PURPOSE:Thoracoscopic repair can be safely performed in most types of congenital esophageal atresia (EA), including in patients with long gap EA or very low birth weight. Accordingly, we performed single- or multistage thoracoscopic repair for various EA types. We aimed to report our therapeutic strategy for thoracosco...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-019-04541-x
更新日期：2019-10-01 00:00:00
abstract：:A case of isolated Caroli's disease in a 2-year-old female presented as an exophytic cystic mass of the liver. A palpable mass below the right costal margin and displacement of the right colon were the main points of clinical presentation. Preoperatively, sonographic signs of intraluminal vascular tracts were identifi...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050281
更新日期：1998-03-01 00:00:00
abstract：INTRODUCTION:Hepatoportoenterostomy (HPE) with the Kasai procedure is the treatment of choice for biliary atresia (BA) as the initial surgery. However, the appropriate level of dissection level of the fibrous cone (FC) of the porta hepatis (PH) is frequently unclear, and the procedure sometimes results in unsuccessful ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3799-4
更新日期：2015-12-01 00:00:00
abstract：:Pyloric atresia (PA) is an uncommon anomaly that may be associated with many other congenital anomalies, the commonest of which is junctional epidermolysis bullosa (JEB). Most of the cases of PA associated with JEB (Herlitz syndrome) reported have been fatal. A case of PA associated with JEB, malrotation, and a high a...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050572
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:The aim of this study is to identify the risk factors for esophageal anastomotic stricture (EAS) and/or anastomotic leakage (EAL) after primary repair of esophageal atresia with tracheoesophageal fistula (EA/TEF) in infants. METHODS:A retrospective chart review of 52 patients with congenital EA/TEF between Jan...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-3931-0
更新日期：2016-09-01 00:00:00
abstract：:Non-operative management of gastroschisis also known as plastic closure (PC) has been described as an alternative to conventional primary operative closure (POC) or staged silo closure (SSC). The aim of this study was to compare these techniques in neonates with gastroschisis. A retrospective review of neonates with g...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-008-2153-5
更新日期：2008-07-01 00:00:00
abstract：:Rhabdoid tumour of the kidney is not common. Presentation of such a lethal tumour along with blunt abdominal trauma is even rarer. We report such a case of Rhabdoid tumour of kidney which presented as renal trauma, and discuss the diagnostic difficulties and rapidly fatal outcome. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003839900290
更新日期：2000-01-01 00:00:00
abstract：:Measurement of testicular volume is a more readily available method of estimating spermatogenesis in adolescence. Traditionally, testicular volumes have been measured with different type of orchidometers or calipers. The most widely used orchidometer is the Prader orchidometer introduced in 1966. This type of orchidom...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1470-1
更新日期：2005-07-01 00:00:00
abstract：PURPOSE:The aim of the German Network for Congenital Uro-REctal malformations (CURE-Net) is to collect data of affected patients with anorectal malformation (ARM) to investigate molecular causes, clinical implications and psychosocial outcome. The current issue was to examine the transition to adulthood in adults with ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-012-3120-8
更新日期：2012-08-01 00:00:00
abstract：:Inflammatory pseudotumors (IPT) are uncommon mass lesions arising most typically in the lungs of young adults. These tumors are so named because of the difficulty in distinguishing them preoperatively from malignant lesions. IPT are characterized histologically by localized fibrous proliferations with infiltration by ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s003830000518
更新日期：2001-09-01 00:00:00
abstract：:Premature male ischiopagus tetrapus twins weighing 2.2 kg were born unexpectedly. They required initial ventilation for respiratory distress syndrome and an emergency laparotomy for intestinal obstruction at 10 days of age. At 8 months of age, formal separation was carried out. Primary skin closure was possible withou...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01372144
更新日期：1997-04-01 00:00:00
abstract：PURPOSE:Pediatric patients with intestinal failure need long-term parenteral nutrition (PN), but this nutritional support causes liver dysfunction, such as intestinal failure-associated liver disease (IFALD). Several studies have shown that the lipid emulsion produced by soybean oil (SO) is associated with the occurren...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-017-4190-4
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:Adhesive small bowel obstruction (ASBO) is one of the most important cause of postoperative morbidity in children who underwent abdominal surgery. Laparoscopic management for ASBO in pediatric patients has been reported. However, its safety and efficacy has not been evaluated in details. The aim of this study i...
journal_title：Pediatric surgery international
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00383-017-4186-0
更新日期：2018-02-01 00:00:00
abstract：PURPOSE:Bicycling is a well-liked sporting activity in which many children participate, and bicycle accidents are one of the most common causes of abdominal injuries in children. We evaluated the characteristics and outcomes of abdominal injuries due to bicycle accidents in children. PATIENTS AND METHODS:This study wa...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-013-3279-7
更新日期：2013-05-01 00:00:00
abstract：:Allgrove syndrome is a rare genetic disorder typically manifested by alacrima, achalasia, and adrenal insufficiency, and is one of the rare causes of achalasia in infants. While the gold standard for achalasia treatment in adults is an esophageal myotomy with fundoplication, a standard treatment for infantile achalasi...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-014-3493-y
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:Fetal extraperitoneal rectal perforation (FERP) is an extremely rare entity. The objective of this report is to review the available literature on this condition and to add our experience with four additional cases managed at our institution. METHODS:A literature search was performed for journal articles addre...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-019-04514-0
更新日期：2019-09-01 00:00:00
