Abstract:
PURPOSE:Pediatric patients with intestinal failure need long-term parenteral nutrition (PN), but this nutritional support causes liver dysfunction, such as intestinal failure-associated liver disease (IFALD). Several studies have shown that the lipid emulsion produced by soybean oil (SO) is associated with the occurrence of IFALD. In this study, we evaluated the effect of SO and fish oil (FO) lipid emulsion on hepatic steatosis. METHODS:Sprague-Dawley rats underwent jugular vein catheterization and were divided into three groups: sham operation with normal chow (Sham group), 80% small bowel resection (80% SBR) + TPN with SO lipid emulsion (SO group), and 80% SBR + TPN with FO lipid emulsion (FO group). All rats were euthanized and the serum biochemistry and hepatic histology analyzed. RESULTS:No significant differences in the serum liver or biliary enzymes were noted between the SO and FO groups. The pathological findings and NAFLD score in the FO group did not show steatosis and were significantly lower than in the SO group. An analysis of the fatty acids profile in the both the SO and FO groups did not indicate essential fatty acid deficiency (EFAD). CONCLUSION:FO lipid emulsion may have a protective role against steatosis of IFALD without EFAD.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Machigashira S,Kaji T,Onishi S,Yamada W,Yano K,Yamada K,Masuya R,Kawano T,Nakame K,Mukai M,Ieiri Sdoi
10.1007/s00383-017-4190-4subject
Has Abstractpub_date
2018-02-01 00:00:00pages
203-209issue
2eissn
0179-0358issn
1437-9813pii
10.1007/s00383-017-4190-4journal_volume
34pub_type
杂志文章abstract::Our purpose was to clarify factors that influence the level of depression of Japanese children with anorectal malformations (ARM). The subjects comprised 66 children with ARM, aged 0-16 years, and their mothers. Patients were divided into three groups (Group 1: aged 0-5 years, Group 2: 6-11 years, and Group 3: 12-16 y...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2077-5
更新日期:2008-03-01 00:00:00
abstract::Modern plastic and reconstructive surgery continues to significantly improve the functional and aesthetic post-burn sequelae in children. It has become a major factor in restoring mobility, aesthetic appearance, self-esteem, and quality of life. The entire spectrum of plastic reconstructive procedures should be availa...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/BF01076930
更新日期:1997-07-01 00:00:00
abstract::In a retrospective study, intraoperative photos and video documentations of 884 children demonstrate that inguinal hernias and their recurrences are aspects of a full spectrum, which ranges from fully closed internal inguinal rings (IIR) and small openings to all-the way-down-into-the-scrotum open processus; 92% of th...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2018-3
更新日期:2007-12-01 00:00:00
abstract::Our presentation of four cases demonstrates the essential features of limb-body wall complex (LBWC), representing a compound anomaly pattern in body-wall defects. The diagnosis of this entity is based on two of the three following characteristics: (1) exencephaly/encephalocele and facial clefts; (2) thoraco- and/or ab...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000497
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:The RAS association domain family protein 1 (RASSF1A) is known to be frequently inactivated by promoter hypermethylation in cancers. This study investigated the association of RASSF1A methylation with clinical outcomes in hepatoblastoma patients and whether it is correlated with the histological phenotype of he...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-013-3371-z
更新日期:2013-11-01 00:00:00
abstract::Coagulopathies associated with malignancies are not extremely rare, but are uncommonly associated with Wilms' tumour (WT). A 6-month-old female with a WT and an abnormal coagulation profile is reported. Due to the Coagulopathy and elevated D-dimers in the blood, surgery was deferred and chemotherapy was given, after w...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0853-9
更新日期:2003-06-01 00:00:00
abstract::Despite hypertrophic pyloric stenosis (HPS) being one of the most frequently treated pediatric surgical conditions, its etiology remains incompletely understood. We review the diagnosis and treatment of this condition with an emphasis on the evolution of surgical techniques that led to laparoscopic pyloromyotomy, the ...
journal_title:Pediatric surgery international
pub_type: 历史文章,杂志文章,评审
doi:10.1007/s00383-017-4196-y
更新日期:2018-01-01 00:00:00
abstract::We examined immunohistochemically the expression and localisation of synapse-associated proteins, syntaxin (SNT) and synaptotagmin (STG) in the entire resected specimens of colon obtained at the time of pull-through operation from 15 patients with Hirschsprung's disease (HD) and 6 age-matched controls. Both antibodies...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050408
更新日期:1998-10-01 00:00:00
abstract::Polyorchidism is defined as the presence of more than two testes. We report the case of a 3-year-old boy and review the embryology and surgical management of the condition. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050247
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:The aims of this study were to assess the short- and long-term complication rates after video-assisted gastrostomy (VAG), the effects of age and gender on long-term complications and the effect of duration of gastrostomy tube retention on the need for gastroraphy when the gastrostomy device was removed. METHOD...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-4001-3
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:Partial hepatectomy (PH) can be an inevitable surgical therapy in some conditions, such as hepatic malignancies, trauma or partial liver transplantation. Its capacity for regeneration distinguishes the liver from other essential organs. Regeneration is a complex process involving growth factors, cytokines, tran...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2529-1
更新日期:2010-02-01 00:00:00
abstract::We present the results of a 6-year review of appendicitis. In the event of diagnostic doubt, a policy of active observation was instituted. This review endorses the validity of such a policy, indicating that it does not expose patients to increased morbidity. Data were collected prospectively over a 6-year period on 1...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000483
更新日期:2001-03-01 00:00:00
abstract::Intestinal mucosal injury of various degrees occurs in many clinical situations and is initially evidenced by altered mucosal permeability. The latter may be assessed in animal models by determination of plasma-to-intestinal lumen clearance of specific molecules, usually chromated 51Cr EDTA. The purpose of this study ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050261
更新日期:1998-03-01 00:00:00
abstract::Recently, laparoscopic orchidopexy has been accepted as the standard procedure of management for clinically impalpable testes. However, many techniques have been described for the delivery of the mobilized testes. In this report, a new approach is described. The use of a fourth "scroto-peritoneal" port, makes complete...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050372
更新日期:1998-07-01 00:00:00
abstract:INTRODUCTION:Management of oesophageal atresia (OA) and trachea-oesophageal fistula (TOF) in babies of low birth weight is challenging especially when associated with other anomalies. Birth weight of <1500 g has previously formed part of a classification system designed to predict outcome, alongside the cardiac status ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3851-4
更新日期:2016-06-01 00:00:00
abstract::Macrophages (MPs) produce increased levels of proinflammatory cytokines in Crohn's disease; these cytokines are thought to play a central role in the occurrence of the disease. Biologics are currently available for anti-cytokine therapy, but treating intestinal inflammation through direct suppression of proinflammator...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1767-8
更新日期:2006-11-01 00:00:00
abstract::"Variants of Hirschsprung's disease" are conditions that clinically resemble Hirschsprung's disease (HD), despite the presence of ganglion cells in rectal suction biopsies. The diagnosis and management of these patients can be challenging. Specific histological, immunohistochemical and electron microscopic investigati...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-013-3351-3
更新日期:2013-09-01 00:00:00
abstract::Anorectal malformations (ARM) remain a significant birth defect with geographic variation in incidence, individual phenotypes and regional geographic subtypes. Although early studies indicated a low incidence in Black patients, there is a great paucity of knowledge as to the types, frequency and incidence of ARMs enco...
journal_title:Pediatric surgery international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00383-008-2131-y
更新日期:2008-06-01 00:00:00
abstract:PURPOSE:Congenital lung abnormalities are rare malformations increasingly detected early by prenatal ultrasound. Whether management of these frequently asymptomatic lesions should be surgical or conservative is an unresolved issue. The necessary prospective studies are limited by the absence of a widely accepted practi...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-017-4062-y
更新日期:2017-06-01 00:00:00
abstract::Pediatric germ cell tumors comprise 1-3% of all malignant pediatric tumors and are found in variable locations. We present the case of a term 3.7 kg neonate who was found to have a giant liver mass at birth, later determined to be an immature teratoma arising from the hepatoduodenal ligament. This case report and imag...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-017-4123-2
更新日期:2017-09-01 00:00:00
abstract::Africa faces a triple burden of disease; HIV, tuberculosis and malaria. Despite this, its population is expected to double over the next 45 years. There is a dire shortage of medical specialists and many countries lack suitably qualified doctors to train medical specialists. Videoconferencing offers the opportunity to...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2085-5
更新日期:2008-02-01 00:00:00
abstract:PURPOSE:We have retrospectively evaluated all patients who underwent endoscopic puncture (EP) of ureterocele over the last 26 years with special reference to the need in the second intervention and disease-free status. METHODS:78 (69%) of the 112 patients following EP and completed follow-up were included. 51 (65%) we...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4258-9
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:To study the effects of frenulotomy on nipple pain, latch and the success in exclusive breastfeeding (EBF) at 3-month follow-up. METHODS:A prospective cross-sectional study of 328 mother-infant pairs with both tongue-tie and breastfeeding problems was performed. Nipple pain and latch were evaluated using numer...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3952-8
更新日期:2016-10-01 00:00:00
abstract::Transanal one-stage endorectal pull-through (TOSEPT) has been presented as the most recent progression in treatment of Hirschsprung's disease (HD), which may be able to replace various previous techniques. This prospective study was designed to compare the efficacy and probable complications of the commonly used open ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2186-9
更新日期:2008-08-01 00:00:00
abstract::Complete transposition of the penis and scrotum, or prepenile scrotum, is an uncommon congenital malformation. Concomitant genitourinary abnormalities, often life-threatening in nature, are frequently seen, and major malformations involving other organ systems may also be present. We report a newborn in whom complete ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050650
更新日期:1999-01-01 00:00:00
abstract::A small phallus causes great concern regarding genital adequacy. A concealed penis, although of normal size, appears small either because it is buried in prepubic tissues, enclosed in scrotal tissue penis palmatus (PP), or trapped due to phimosis or a scar following circumcision or trauma. From July 1978 to January 20...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0770-y
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:Ultraviolet (UV) radiation adversely affects skin health at cellular and molecular levels. Hence, UV radiation can directly induce inflammatory responses in the dermis by inducing erythema, edema, inflammation, dermal fibroblasts alterations, and extracellular matrix modifications. METHODS:Human keratinocytes,...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4384-4
更新日期:2019-01-01 00:00:00
abstract::Meckel's diverticulum has previously been reported to be present in patients with Crohn's disease. However, the finding is typically an incidental one, and involvement of the diverticulum in the disease process is uncommon. We report a case of an adolescent with known Crohn's disease who presented with symptoms though...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-1971-1
更新日期:2008-03-01 00:00:00
abstract::Accessory hepatic tissue, unlike accessory splenic and pancreatic tissue, is rare and has a limited and almost exclusively sub diaphragmatic distribution. Fewer than ten cases of intrathoracic ectopic liver have been reported so far in the literature. This paper reports a case that caused a diagnostic dilemma. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s003830000520
更新日期:2001-07-01 00:00:00
abstract::The intrinsic innervation of the developing gut has long been a subject of investigation, but little is known regarding that of the embryonic cloaca. The cloaca, like the rest of the gastrointestinal tract, is intrinsically innervated by the enteric nervous system. Nitrergic neurons and fibres make up a large part of ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1590-7
更新日期:2006-01-01 00:00:00