Abstract:
:Despite hypertrophic pyloric stenosis (HPS) being one of the most frequently treated pediatric surgical conditions, its etiology remains incompletely understood. We review the diagnosis and treatment of this condition with an emphasis on the evolution of surgical techniques that led to laparoscopic pyloromyotomy, the most frequently performed technique for HPS today. In addition, we review key developments in the understanding of HPS etiology and treatment, including the postulated etiology of work-induced hypertrophy of the pylorus, its association with prokinetic macrolide antibiotics, and the emerging role of atropine sulfate as a medical treatment for HPS or a rescue treatment for incomplete myotomy.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
El-Gohary Y,Abdelhafeez A,Paton E,Gosain A,Murphy AJdoi
10.1007/s00383-017-4196-ysubject
Has Abstractpub_date
2018-01-01 00:00:00pages
21-27issue
1eissn
0179-0358issn
1437-9813pii
10.1007/s00383-017-4196-yjournal_volume
34pub_type
历史文章,杂志文章,评审abstract:PURPOSE:The pathophysiology of Hirschsprung's disease (HSCR) is not entirely understood. There is no clear explanation for the occurrence of the spastic or tonically contracted aganglionic segment of bowel. Kv11.1 (hERG) channels play a critical role in the regulation of the resting membrane potential as well as affect...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3807-8
更新日期:2016-01-01 00:00:00
abstract::A new instrument for suction rectal biopsy in infants suspected of having Hirschsprung's disease is described that can be completely dismantled, physically cleaned, lubricated, and heat-sterilised. These attributes are new and are absolutely critical today. The instrument has been used in 60 patients (ca. 180 biopsies...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF01194812
更新日期:1997-01-01 00:00:00
abstract::Rhabdoid tumour of the kidney is not common. Presentation of such a lethal tumour along with blunt abdominal trauma is even rarer. We report such a case of Rhabdoid tumour of kidney which presented as renal trauma, and discuss the diagnostic difficulties and rapidly fatal outcome. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003839900290
更新日期:2000-01-01 00:00:00
abstract::Aim was to describe the challenges faced in the management of bilateral multicystic kidney disease (MCKD). A case of antenatally detected bilateral polycystic disease was referred at 28 weeks of gestation. The patient was advised to continue pregnancy till term and be in regular follow-up. Postnatally, the male baby p...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-007-1962-2
更新日期:2007-08-01 00:00:00
abstract::Numerous case reports in the literature have suggested a causal link between beta-haemolytic streptococcal infection and delayed-onset right-sided diaphragmatic hernia/eventration in the perinatal age group. We report a child with antenatally documented right diaphragmatic eventration 4 weeks before birth who subseque...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:
更新日期:1997-03-21 00:00:00
abstract:BACKGROUND:Subclinical varicocele is a relative rare condition. The aim of this study is to identify the role of bioflavonoids in the management of subclinical varicocele. MATERIALS AND METHODS:We analyzed the medical charts of patients treated for subclinical varicocele with bioflavonoids between 1999 and 2004; inclu...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-010-2574-9
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:The objective of this study was to characterize the clinical course and outcomes of children with pancreatic pseudocysts that were initially treated non-operatively or with percutaneous drainage. METHODS:A retrospective review of children with pancreatic pseudocysts over a 12-year period was completed. Categor...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3236-x
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:Biliary atresia (BA) is characterized by progressive inflammation of the biliary system. This inflammation persists and causes liver fibrosis, although jaundice disappears after Kasai portoenterostomy (KP). We aimed to confirm whether the oral administration of eicosapentaenoic acid (EPA) suppresses liver fibro...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4313-6
更新日期:2018-10-01 00:00:00
abstract::Laparoscopy enables surgeons to approach the surgical conditions from a new perspective. Laparoscopic surgery has revolutionized the treatment of choledochal cysts (CDC). Yet, this new technique requires objective evaluations. We have examined the controversies about the CDC dissection, distal common bile duct ligatio...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-013-3266-z
更新日期:2013-04-01 00:00:00
abstract:PURPOSE:Sacrococcygeal teratoma (SCT) is the most common congenital neoplasm in neonates. We wished to assess the long-term functional outcome of children undergoing SCT resection. METHODS:Records of neonates diagnosed with SCT from two surgeons' practices, and operated on between 1970 and 2006, were retrospectively r...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2322-1
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:Laparoscopic Kasai portoenterostomy was reported to be a safe and feasible procedure in infant with biliary atresia. We aimed to investigate the long-term results after laparoscopic portoenterostomy as such data in the literature are lacking. METHODS:Sixteen infants underwent laparoscopic Kasai portoenterostom...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3172-9
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVES:This study reviews the results of our previously described modification of the minimally invasive (Nuss) procedure for correction of pectus excavatum. It utilizes a subxyphoid incision with central fixation to maximize safe bar passage and minimize bar displacement. METHODS:Consecutive patients corrected wi...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-017-4195-z
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Applicants in the NRMP for pediatric surgery have little objective data available regarding factors predicting successful matching. We analyzed data from applicants at our institution to attempt to identify parameters correlated with three outcomes: successfully matching, or attaining either a top ten or t...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-2912-6
更新日期:2011-11-01 00:00:00
abstract::Surgical repair of acquired tracheo-esophageal fistula may result in tracheal stenosis or esophageal stricture. We used fistula with esophageal cuff as flap to repair the tracheal defect. Esophageal repair was performed by rotating ends through 90° in opposite direction. This technique offers excellent repair in a sin...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3498-6
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:To investigate the safety and efficacy of mucous fistula refeeding (MFR) in low-birth-weight infants. METHODS:Between December 2006 and December 2018, medical records of low-birth-weight infants who underwent small bowel enterostomy formation in the neonatal period and subsequent stoma closure at our instituti...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-019-04533-x
更新日期:2019-10-01 00:00:00
abstract::Recently, most studies reported magnesium as a N-methyl-D-aspartate receptor antagonist and its analgesic and perioperative anaesthetic effects have been discussed with central desensitization pathway. We investigated the effects of caudal ropivacaine plus magnesium and compared with ropivacaine alone on postoperative...
journal_title:Pediatric surgery international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00383-006-1779-4
更新日期:2007-02-01 00:00:00
abstract::We examined immunohistochemically the expression and localisation of synapse-associated proteins, syntaxin (SNT) and synaptotagmin (STG) in the entire resected specimens of colon obtained at the time of pull-through operation from 15 patients with Hirschsprung's disease (HD) and 6 age-matched controls. Both antibodies...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050408
更新日期:1998-10-01 00:00:00
abstract::Transanal one-stage endorectal pull-through (TOSEPT) has been presented as the most recent progression in treatment of Hirschsprung's disease (HD), which may be able to replace various previous techniques. This prospective study was designed to compare the efficacy and probable complications of the commonly used open ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2186-9
更新日期:2008-08-01 00:00:00
abstract::Endoscopic management is the accepted form of treatment for posterior urethral valves (PUV). The Nd:YAG laser has been in clinical use for many decades, but has been used only sporadically for ablating PUV. In this study, PUV were diagnosed by micturating cystourethrogram (MCU). In the 9-month period beginning March 1...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050018
更新日期:2000-01-01 00:00:00
abstract::Esophageal hiatal hernias (EHH) are probably caused by congenital, traumatic, or iatrogenic factors, although the etiology remains unknown. EHHs may develop after abdominal wall closure for omphalocele or gastroschisis due to the increased intra-abdominal pressure, however, there have been few reports in the literatur...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050352
更新日期:1998-07-01 00:00:00
abstract::Beckwith-Wiedemann Syndrome (BWS) is associated with somatic overgrowth and a high risk for embryonal tumors, including hepatoblastoma, a highly malignant liver tumor of childhood. Focal nodular hyperplasia (FNH), on the other hand, is a benign tumor of the liver that is uncommon in childhood. Herein we describe a cas...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1469-7
更新日期:2005-09-01 00:00:00
abstract::Reflux nephropathy (RN) is recognized as a major cause of end-stage renal failure in children and young adults. Inhibition of nitric oxide (NO) exacerbates and enhanced production ameliorates tubulointerstitial fibrosis (TIF) in experimental obstructive uropathy. NO is synthesised by NO synthase (NOS), three distinct ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0858-4
更新日期:2002-10-01 00:00:00
abstract:UNLABELLED:Anorectal malformation (ARM) is a group of significant birth defects with geographic variation in incidence, individual phenotypes and regional geographic subtypes occurring in approximately 1:5,000 live births. Anorectal atresia with gross terminal colonic distension in the presence of an absent anal canal ...
journal_title:Pediatric surgery international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00383-013-3346-0
更新日期:2013-12-01 00:00:00
abstract::Polyps in gastrointestinal tract are mostly benign and result from hamartomas or lymphoid hyperplasia of submucosa. They usually occur as isolated lesions in children and are referred to as juvenile polyps. Multiple polyps with inherited origin are called polyposis and can be seen as a part of the syndrome. The polyps...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-020-04621-3
更新日期:2020-04-01 00:00:00
abstract:AIM:Prepubertal testicular tumors are rare in children. We aim to present clinical and histological features of prepubertal testicular tumors through the analysis of the long-term experiences of a single medical center of China. MATERIALS AND METHODS:A total of 67 children (≤ 14 years) treated for testicular tumor at ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4366-6
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:The aim of this study was to determine if there is a difference between complications for totally implantable central venous catheters (ports) and tunnelled external central venous catheters (external CVCs) that result in early removal of the central venous catheter (CVC) in children and adolescents with acute ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3213-4
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:The Nuss procedure is a minimally invasive procedure for the correction of pectus excavatum. It involves insertion of a substernal metal bar. A feared complication of any implantation procedure is infection, which often requires removal of the implanted device. This report describes the authors' experience with...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3145-z
更新日期:2012-09-01 00:00:00
abstract::The purpose of this report was to analyze the patients requiring preoperative extracorporeal membrane oxygenation (ECMO) as the most critical group of patients with congenital diaphragmatic hernia (CDH) and to identify any special features. Over the past 11 years, out of 72 neonates with CDH admitted before 24 h of ag...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050428
更新日期:1998-11-01 00:00:00
abstract:AIM:Although liver abscess (LA) is prevalent worldwide, especially in developing countries, there is a paucity of data regarding the protocol for management of LA in children. The aim of this study was to analyze the outcome of a protocol-based management of pediatric LA from a single institution. MATERIALS AND METHOD...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-4009-8
更新日期:2017-02-01 00:00:00
abstract:INTRODUCTION:Objectively evaluating the lack of bowel control (fecal incontinence) continues to be a challenge. Many have attempted to measure the severity of fecal incontinence and to evaluate its impact on the quality of life by developing standardized scoring systems. Some of these systems have been validated but no...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-016-3909-y
更新日期:2016-08-01 00:00:00