Abstract:
:Aim was to describe the challenges faced in the management of bilateral multicystic kidney disease (MCKD). A case of antenatally detected bilateral polycystic disease was referred at 28 weeks of gestation. The patient was advised to continue pregnancy till term and be in regular follow-up. Postnatally, the male baby passed urine in normal stream and was diagnosed as bilateral multicystic kidney disease on ultrasonography. He developed symptoms of renal failure. The baby was operated with right pyeloplasty and left pyelostomy, as the left ureter was atretic. The histopathology was consistent with bilateral multicystic kidney disease. Postoperatively, the baby was stable with intermittent episodes of metabolic acidosis that were managed medically and with peritoneal dialysis. Autologous stem cells were injected at the age of 1 year into the aorta at the level of the renal arteries clamping the aorta below. Repeat biopsy at time of stem cell injection showed 5/10 glomeruli showing global sclerosis on right side and 5/15 glomeruli showing global sclerosis on left side. The only improvement seen was in decreased doses of medicines to keep the child metabolically stable. The baby kept struggling but succumbed at the age of 17 months and 15 days. Post mortem bilateral renal biopsies demonstrated presence of primitive renal tubules and blastemal cells that were not demonstrated earlier. Survival for few months in bilateral multicystic kidney disease is thus possible with adequate treatment, the novel use of stem cells in these cases may prove beneficial in future though it is too early to comment further.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Sharma S,Gupta DK,Kumar L,Dinda AK,Bagga A,Mohanty Sdoi
10.1007/s00383-007-1962-2subject
Has Abstractpub_date
2007-08-01 00:00:00pages
801-6issue
8eissn
0179-0358issn
1437-9813journal_volume
23pub_type
杂志文章,评审abstract:PURPOSE:The aim of this study was to determine if the placement of prophylactic drains influences the incidence of postoperative adverse events in neonates. METHODS:Neonatal patients undergoing laparotomy between April 2000 and December 2007 were prospectively assigned to aggressive peritoneal cavity lavage, without t...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-2905-5
更新日期:2011-09-01 00:00:00
abstract::Juvenile papillomatosis (JP) is a rare benign, proliferative breast tumor in children. We observed a 9-year-old girl with a large soft-tissue mass at the lower outer quadrant of the left breast. Ultrasonography showed an ill-defined, inhomogeneous mass with numerous small, hypoechoic areas. The tumor was completely ex...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000462
更新日期:2001-03-01 00:00:00
abstract:PURPOSE:To evaluate the role of bone marrow-derived mononuclear cells (BMC) in rat bile duct ligation (BDL) model. METHODS:Wistar rats were categorized into four Groups A-D. Normal liver biopsy was taken from Group A. BDL model was created in Groups B and C (15 each). Normal saline and BMC were injected through portal...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-013-3314-8
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:Several procedures have been described for repair of distal hypospadias. However, these are not without any complications. Corpus spongiosum advancement is a new technique employed in our patients for distal hypospadias repair with excellent clinical outcome and no post-operative complications. PATIENTS AND ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-013-3292-x
更新日期:2013-06-01 00:00:00
abstract::Thyroglossal duct cyst (TGDC) disease, one of the most common developmental neck lesion in the pediatric population, often presents as infected neck mass. The authors reviewed their experience in the management of inflamed TGDC cases, in order to suggest the most efficient approach of these patients regarding the idea...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1562-y
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:We evaluated the effectiveness of prophylactic mesenteric lymphatic ligation in preventing iatrogenic chylous fistulae in abdominal neuroblastoma surgery. METHOD:All patients who underwent resection of abdominal neuroblastoma between years 2002 and 2013 were included. A change in surgical strategy commenced fr...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3581-z
更新日期:2014-10-01 00:00:00
abstract::A neonate with a constellation of unusual congenital deformities associated with pulmonary agenesis is reported. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050603
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:Rats are common intruders into human settlements. Apart from their role as disease vectors, they can also cause bite injuries. We describe the clinical course of a series of children with rat bites, and characterise the injures. METHODS:A retrospective review of hospital records of children admitted for rat bi...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04799-6
更新日期:2021-01-21 00:00:00
abstract::Phylloides tumor is an uncommon breast tumor in children. Only a few cases have been reported in the literature. A case of borderline phylloides tumor in an 11-year-old girl is described. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050623
更新日期:1999-07-01 00:00:00
abstract::At bilateral orchiopexy bilateral biopsies may be indicated to determine fertility potential. It is currently unknown if the serum inhibin B levels at time of orchiopexy reflect the testicular status of the bilaterally cryptorchid child. The aim of this study was to relate the results of inhibin B and FSH measurements...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1839-9
更新日期:2007-02-01 00:00:00
abstract:PURPOSE:With the widespread use of the obstetrical ultrasound, identification of a fetal suprarenal mass has become more common. Most of these masses prove to be congenital neuroblastomas (CNB), but the diagnosis is often confused with other benign lesions and the postnatal management remains to be controversial. METH...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2531-7
更新日期:2010-03-01 00:00:00
abstract::"Variants of Hirschsprung's disease" are conditions that clinically resemble Hirschsprung's disease (HD), despite the presence of ganglion cells in rectal suction biopsies. The diagnosis and management of these patients can be challenging. Specific histological, immunohistochemical and electron microscopic investigati...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-013-3351-3
更新日期:2013-09-01 00:00:00
abstract::Desmoplastic small round cell tumour (DSRCT) is an extremely rare neoplasm. Adolescent males and young adults are most frequently affected. It is highly malignant, with only 29% of patients surviving up to 3 years. This paper documents two cases, one of which, at 4 years old, is the second youngest case documented. Ca...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1401-1
更新日期:2005-04-01 00:00:00
abstract::A 31-year-old man who died of metastatic adenocarcinoma of the sigmoid colon had undergone bilateral ureterosigmoidostomy for exstrophy of the bladder 20 years earlier. The patient never underwent a colonoscopy. Neoplastic transformation at the ureterosigmoid anastomosis must be considered as a possible severe complic...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050458
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:For esophagus tissue engineering, isolation and proliferation of esophageal epithelial cells (EEC) is a pre-requisite for scaffold seeding to create constructs. The aim of this study was to sort EEC expressing cytokeratin markers and their proliferative subpopulations; also, to investigate the viability of di...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2512-x
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:Tracheoesophageal fistula (TEF) is a bellwether for a country's ability to care for sick newborns. We aim to review the existing literature from low- and middle-income countries in regard to management of those newborns and the possible approaches to improve their outcomes. METHODS:A review of the existing Eng...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-020-04639-7
更新日期:2020-05-01 00:00:00
abstract::A review of 100 consecutive cases of congenital diaphragmatic hernia (CDH) treated at our institute focusing on the efficacy of protocolized management (PM) was conducted. Of the 100 cases, 14 who became symptomatic more than 24 h after birth, and seven with fatal anomalies (four cardiac and three chromosomal) were ex...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1759-8
更新日期:2006-11-01 00:00:00
abstract:PURPOSE:To report the authors' experience in the management of perforated choledochal cyst with bile peritonitis (PCC) in children. METHODS:Medical records of all children undergoing surgery for PCC at our hospital from May, 2005 to January, 2013 were reviewed. RESULTS:Twenty seven patients were identified, with a me...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3461-6
更新日期:2014-03-01 00:00:00
abstract::The purpose of this study is to evaluate the efficacy of intraoperative radiation therapy (IORT) and the problem of securing the IORT field in advanced pediatric neuroblastoma. Between 1996 and 2005, 12 children received IORT for advanced pediatric neuroblastoma patients. Electron beam energies ranged from 10 to 12 Me...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2065-9
更新日期:2007-12-01 00:00:00
abstract::A retrospective study of all cases (n = 21) of congenital lobar emphysema (CLE) treated at the Royal Hospital, Muscat, from September 1988 to August 1999 was performed. The presentation, diagnosis, treatment, and outcome are reviewed. All 21 patients were nonwhite. Thirteen had left-upper-lobe, 7 right-middle-lobe, an...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000506
更新日期:2001-03-01 00:00:00
abstract::Rhabdomyosarcoma (RMS) is the most common soft tissue tumour in children. This is the first time a facial RMS metastatic to the pancreas is reported. The patient was a 3-year-old boy with a symptomatic solitary pancreatic metastasis of a primary facial RMS, with already one relapse in a submental lymph node. Since thi...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2539-z
更新日期:2010-03-01 00:00:00
abstract::Eighty-three gastric transpositions for oesophageal replacement were carried out over the 15-year period 1981-1995. The vast majority of patients underwent the replacement procedure for oesophageal atresia (OA) (56), 35 following failed or abandoned attempts at primary anastomosis, and 21 for isolated atresia. Caustic...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00178420
更新日期:1996-04-01 00:00:00
abstract:PURPOSE:Although Rex shunt is an effective treatment for extrahepatic portal venous obstruction (EHPVO), 4-20% children develop rebleeding postoperatively. This study was used to evaluate the surgical treatment of rebleeding after Rex shunt in our center. METHOD:From June 2008 to Jan 2017, 12 of 122 children with EHPV...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4246-0
更新日期:2018-05-01 00:00:00
abstract::The Thomsen-Friedenreich cryptantigen (TCA) is located on the surface of all red cells, but is concealed by a layer of neuraminic acid. When bacteria that produce neuraminidase disrupt this coating, the TCA can be exposed and activated. If blood products containing antibody to the TCA are subsequently administered, ha...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050488
更新日期:1998-12-01 00:00:00
abstract:PURPOSE:We have retrospectively evaluated all patients who underwent endoscopic puncture (EP) of ureterocele over the last 26 years with special reference to the need in the second intervention and disease-free status. METHODS:78 (69%) of the 112 patients following EP and completed follow-up were included. 51 (65%) we...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4258-9
更新日期:2018-05-01 00:00:00
abstract::We reviewed our clinical experience of using a computer-powered right angle linear cutter (CPRALC) for Collis-Nissen fundoplication (CNF) in three children with gastroesophageal reflux (GER) or failed Nissen associated with short esophagus. Case 1 was a 13-month-old female with persistent GER after type-C esophageal a...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2455-2
更新日期:2009-11-01 00:00:00
abstract::Non-accidental trauma (NAT) represents a significant cause of morbidity and mortality in the pediatric population. The management of these patients often involves many care providers including the surgeon. Victims of NAT often present with multiple injuries and as such should be treated as trauma patients with complet...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-015-3688-x
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:Chronological age has not always been an accurate predictor of gut motility in newborns. We hypothesized that the enteric plexus is immature at birth. We studied whole-mount preparations of the myenteric plexus in pigs from mid-point of gestation to adulthood. METHODS:Distal large bowel whole-mount preparation...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2265-y
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Pediatric patients with medically refractory ulcerative colitis (UC) often undergo an initial subtotal colectomy end ileostomy (STC-I). The role of fecal diversion in the subsequent completion proctectomy/ileal-pouch anal anastomosis (CP-IPAA) remains controversial. METHODS:A multi-institutional retrospecti...
journal_title:Pediatric surgery international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00383-019-04440-1
更新日期:2019-04-01 00:00:00
abstract::The introduction of posterior sagittal anorectoplasty (PSARP) by deVries and Peña in the early 80s has impacted to the treatment of patients with anorectal malformations (ARM). It gained great recognition worldwide in a very short time, and since then, surgeons dealing with the treatment of this complex malformation c...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-020-04629-9
更新日期:2020-04-01 00:00:00