Could adding magnesium as adjuvant to ropivacaine in caudal anaesthesia improve postoperative pain control?

Abstract:

:Recently, most studies reported magnesium as a N-methyl-D-aspartate receptor antagonist and its analgesic and perioperative anaesthetic effects have been discussed with central desensitization pathway. We investigated the effects of caudal ropivacaine plus magnesium and compared with ropivacaine alone on postoperative analgesia requirements. After hospital ethic committee's consent, 60 patients (ASA I-II, 2-10 years old) who had lower abdominal or penoscrotal surgery were enrolled in the study. After general anaesthesia induction, caudal blockage was applied. Patients were randomly assigned in two groups. Ropivacaine 0.25% was administered to Group R (n=37), ropivacaine 0.25% plus 50 mg magnesium to Group RM (n=23) in 0.5 ml kg-1 volume. Postoperative analgesia level was recorded at 15 min and 1, 2, 3, 4, 6 h by using Paediatric Objective Pain Scale (POPS) and The Children's Hospital of Eastern Ontoria Pain Scale (CHEOPS). Postoperative motor blocks were evaluated with Modified Bromage Motor Block Scale. According to demographic characteristics, there were no significant differences between the two groups (P>0.05). POPS, CHEOPS, Bromage Motor Scales, analgesia duration and adverse effects were similar in Group R and Group RM. It has been shown that addition of magnesium as an adjuvant agent to local anaesthetics for caudal analgesia has no effect on postoperative pain and analgesic need.

journal_name

Pediatr Surg Int

authors

Birbicer H,Doruk N,Cinel I,Atici S,Avlan D,Bilgin E,Oral U

doi

10.1007/s00383-006-1779-4

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

195-8

issue

2

eissn

0179-0358

issn

1437-9813

journal_volume

23

pub_type

杂志文章,随机对照试验
  • Suppression of proinflammatory cytokine production in macrophages by lansoprazole.

    abstract::Macrophages (MPs) produce increased levels of proinflammatory cytokines in Crohn's disease; these cytokines are thought to play a central role in the occurrence of the disease. Biologics are currently available for anti-cytokine therapy, but treating intestinal inflammation through direct suppression of proinflammator...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-006-1767-8

    authors: Hinoki A,Yoshimura K,Fujita K,Akita M,Ikeda R,Nagashima M,Nomura M,Satomi A

    更新日期:2006-11-01 00:00:00

  • Introduction of resection of intrahepatic bile duct stenosis-causing membrane or septum into laparoscopic choledochal cyst excision.

    abstract:PURPOSE:We previously showed that meticulous probing and resection of the intrahepatic bile duct stenosis (IHBDS)-causing membrane or septum was effective in preventing hepatolithiasis after choledochal cyst excisions in open surgeries. Then, we introduced this maneuver into laparoscopic choledochal cyst excisions in 2...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4320-7

    authors: Tanaka Y,Tainaka T,Sumida W,Hinoki A,Shirota C,Murase N,Oshima K,Shirotsuki R,Chiba K,Uchida H

    更新日期:2018-10-01 00:00:00

  • Surgical treatment of infantile achalasia: a case report and literature review.

    abstract::Allgrove syndrome is a rare genetic disorder typically manifested by alacrima, achalasia, and adrenal insufficiency, and is one of the rare causes of achalasia in infants. While the gold standard for achalasia treatment in adults is an esophageal myotomy with fundoplication, a standard treatment for infantile achalasi...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审

    doi:10.1007/s00383-014-3493-y

    authors: Li Y,Fallon SC,Helmrath MA,Gilger M,Brandt ML

    更新日期:2014-06-01 00:00:00

  • Neurosurgical management of hydrocephalus by a general surgeon in an extremely low resource setting: initial experience in North Kivu province of Eastern Democratic Republic of Congo.

    abstract:PURPOSE:Evaluate the management of hydrocephalus in pediatric patients in the Eastern Democratic Republic of Congo by a general surgeon. METHODS:Retrospective review of a single institution in the province of North Kivu. Patient charts and surgical notes were reviewed from 2003 to 2016. RESULTS:116 procedures were pe...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4238-0

    authors: Cairo SB,Agyei J,Nyavandu K,Rothstein DH,Kalisya LM

    更新日期:2018-04-01 00:00:00

  • Pyloric stenosis: an enigma more than a century after the first successful treatment.

    abstract::Despite hypertrophic pyloric stenosis (HPS) being one of the most frequently treated pediatric surgical conditions, its etiology remains incompletely understood. We review the diagnosis and treatment of this condition with an emphasis on the evolution of surgical techniques that led to laparoscopic pyloromyotomy, the ...

    journal_title:Pediatric surgery international

    pub_type: 历史文章,杂志文章,评审

    doi:10.1007/s00383-017-4196-y

    authors: El-Gohary Y,Abdelhafeez A,Paton E,Gosain A,Murphy AJ

    更新日期:2018-01-01 00:00:00

  • Surgery for ulcerative colitis in pediatric patients: functional results of 10-year follow-up with straight endorectal pull-through.

    abstract::Children and adolescents affected by ulcerative colitis (UC) frequently require colectomy because of refractory or chronic symptoms. The aim of this paper is to present our experience and 10-year follow-up results of 28 patients who underwent endorectal pull-through (ERPT) as surgical treatment for UC, with special re...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-004-1232-5

    authors: Ceriati E,Deganello F,De Peppo F,Ciprandi G,Silveri M,Marchetti P,Ravà L,Rivosecchi M

    更新日期:2004-08-01 00:00:00

  • Do infants with gastroschisis may have a high incidence of non-IgE-mediated cow's milk protein allergy?

    abstract:BACKGROUND/PURPOSE:To determine the frequency and characteristics of suspected cow's milk protein allergy (CMPA) in infants with gastroschisis and response to change in milk. METHODS:A retrospective cohort study of 111 consecutive infants with gastroschisis. RESULTS:64 episodes suggesting non-IgE-mediated CMPA occurr...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-015-3664-5

    authors: Burge D,Drewett M,Hall N

    更新日期:2015-03-01 00:00:00

  • Management of fetal extraperitoneal rectal perforation: a case series and review of the literature.

    abstract:PURPOSE:Fetal extraperitoneal rectal perforation (FERP) is an extremely rare entity. The objective of this report is to review the available literature on this condition and to add our experience with four additional cases managed at our institution. METHODS:A literature search was performed for journal articles addre...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审

    doi:10.1007/s00383-019-04514-0

    authors: Charlton R,Brisighelli G,Gabler T,Westgarth-Taylor C

    更新日期:2019-09-01 00:00:00

  • Modified PATIO repair for urethrocutaneous fistula post-hypospadias repair: operative technique and outcomes.

    abstract:BACKGROUND:To describe a modification of PATIO repair for urethrocutaneous fistula repair and evaluate its outcome. METHODS:We studied 15 boys who underwent modified PATIO repair from Jan 2010 to Sept 2015. Parameters studied included age, type of hypospadias, age at first urethroplasty, hypospadias repair technique, ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-016-3983-1

    authors: Rathod K,Loyal J,More B,Rajimwale A

    更新日期:2017-01-01 00:00:00

  • Adrenocortical tumors in childhood.

    abstract::Adrenocortical tumors (ACT) are rare in childhood. Determination of malignant potential is difficult. To assess the presentation, clinical behaviour, and histology of these tumors in our center, the records of nine patients with ACTs between 1989 and 2000 were analyzed. The age, sex, clinical presentation, investigati...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-002-0727-1

    authors: Narasimhan KL,Samujh R,Bhansali A,Marwaha RK,Chowdhary SK,Radotra BD,Rao KL

    更新日期:2003-08-01 00:00:00

  • Colchicine in experimental alkaline burns of the rat esophagus: an old drug, a new indication?

    abstract:AIM:An experimental study was performed to investigate the efficacy of colchicine in the prevention of fibrosis in the alkaline burn of the esophagus in rats. METHOD:A standard esophageal alkaline burn was produced by the application of 37.5% NaOH for a period of 90 s to the distal esophagus followed by a water rinse....

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-006-1644-5

    authors: Yukselen V,Vardar E,Yukselen O,Karaoglu AO,Yenisey C,Ozutemiz O

    更新日期:2006-04-01 00:00:00

  • Effects of gabexate mesilate on ischemia-reperfusion-induced testicular injury in rats.

    abstract::The aim of this study was to determine the effects of a synthetic serine protease inhibitor, gabexate mesilate (GM), in rats with ischemia-reperfusion (I-R) damage due to unilateral testicular torsion. Thirty male Sprague-Dawley rats were separated into three groups, each containing ten rats. A sham operation was perf...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-006-1667-y

    authors: Gezici A,Ozturk H,Buyukbayram H,Ozturk H,Okur H

    更新日期:2006-05-01 00:00:00

  • Late-onset vital complication after the Nuss procedure for pectus excavatum.

    abstract::The Nuss procedure is the most popular technique for correction of pectus excavatum recently. Life-threatening complications associated with the procedure are very rare. We report a 13-year-old boy who developed late-onset bilateral hemothorax with hypovolemic shock 5 months after the Nuss procedure. In literature rev...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-011-2936-y

    authors: Lin CW,Chen KC,Diau GY,Chu CC

    更新日期:2012-01-01 00:00:00

  • What is the optimal surgical strategy for complex perianal fistulous disease in pediatric Crohn's disease? A systematic review.

    abstract:PURPOSE:Perianal fistulous disease is present in 10-15% of children with Crohn's disease (CD) and is frequently complex and refractory to treatment, with one-third of patients having recurrent lesions. We conducted a systematic review of the literature to examine the best surgical strategy or strategies for pediatric c...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审

    doi:10.1007/s00383-017-4067-6

    authors: Kantor N,Wayne C,Nasr A

    更新日期:2017-05-01 00:00:00

  • Coagulopathy associated with Wilms' tumour: a rare complication.

    abstract::Coagulopathies associated with malignancies are not extremely rare, but are uncommonly associated with Wilms' tumour (WT). A 6-month-old female with a WT and an abnormal coagulation profile is reported. Due to the Coagulopathy and elevated D-dimers in the blood, surgery was deferred and chemotherapy was given, after w...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-002-0853-9

    authors: Singh S,Singh D,Baheti G,Karmarkar SJ

    更新日期:2003-06-01 00:00:00

  • Omental infarction: an unusual cause of acute abdomen in children.

    abstract::Acute abdomen is caused by a wide variety of etiologies, many of which require surgical intervention. Two boys were hospitalized for acute abdominal pain and low-grade fever. Physical examination revealed epigastric and right upper abdominal fullness, and laboratory studies showed elevated erythrocyte sedimentation ra...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-002-0942-9

    authors: Nagar H,Kessler A,Ben-Sira L,Klepikov I,Wiess J,Graif M

    更新日期:2003-11-01 00:00:00

  • Tunica vaginalis reinforcement flap in reoperative Snodgrass procedure.

    abstract::Interposing vascularized flaps between urethra and skin sutures is recommended in hypospadias surgery to decrease the rate of urethrocutaneous fistula. For this purpose nine patients with failed results after at least one hypospadias surgery and with insufficient foreskin were included in the study. Tubularized incise...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-003-0989-2

    authors: Gürdal M,Karaman MI,Kanberoğlu H,Kireççi S

    更新日期:2003-11-01 00:00:00

  • Is renal scintigraphy really a necessity in the routine diagnosis of congenital solitary kidney?

    abstract:BACKGROUND:For a definitive diagnosis of congenital solitary kidney, renal scintigraphy is suggested as being the gold standard of ruling out ectopic functioning renal tissue, possibly missed by ultrasound. The aim of our study was to test ultrasonography precision in comparison with renal scintigraphy on a larger coho...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-019-04478-1

    authors: Grabnar J,Rus RR

    更新日期:2019-06-01 00:00:00

  • A new instrument for suction rectal biopsy in the diagnosis of Hirschsprung's disease.

    abstract::A new instrument for suction rectal biopsy in infants suspected of having Hirschsprung's disease is described that can be completely dismantled, physically cleaned, lubricated, and heat-sterilised. These attributes are new and are absolutely critical today. The instrument has been used in 60 patients (ca. 180 biopsies...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/BF01194812

    authors: Freeman JK

    更新日期:1997-01-01 00:00:00

  • Unilateral spermatic vessel ligation in prepubertal rats decreases microvascular blood flow to ipsilateral testis postpubertally.

    abstract::High ligation of spermatic vessels (HLSV) and low ligation of spermatic vessels (LLSV) have been described in the surgical treatment of high undescended testis. Testicular capillary blood flow utilizing laser Doppler flowmetry after these maneuvers has not been studied thus far; hence, this study was designed. Thirty ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-003-1018-1

    authors: Srinivas M,Kilmartin B,Basham P,Puri P

    更新日期:2003-07-01 00:00:00

  • Near-infrared fluorescence cholangiography with indocyanine green for biliary atresia. Real-time imaging during the Kasai procedure: a pilot study.

    abstract:INTRODUCTION:Hepatoportoenterostomy (HPE) with the Kasai procedure is the treatment of choice for biliary atresia (BA) as the initial surgery. However, the appropriate level of dissection level of the fibrous cone (FC) of the porta hepatis (PH) is frequently unclear, and the procedure sometimes results in unsuccessful ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-015-3799-4

    authors: Hirayama Y,Iinuma Y,Yokoyama N,Otani T,Masui D,Komatsuzaki N,Higashidate N,Tsuruhisa S,Iida H,Nakaya K,Naito S,Nitta K,Yagi M

    更新日期:2015-12-01 00:00:00

  • Surgical jejunostomy and radiological gastro-jejunostomy tube feeding in children: risks, benefits and nutritional outcomes.

    abstract:PURPOSE:Radiologically inserted gastrojejunal tubes (RGJ) and surgical jejunostomy (SJ) are established modes of jejunal feeding. The aim of the study is to review nutritional outcomes, complications and the practical consideration to enable patients and carers to make informed choice. METHODS:Retrospective review of ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-018-4303-8

    authors: Singh RR,Eaton S,Roebuck DJ,Barnacle AM,Chippington S,Cross KMK,De Coppi P,Curry JI

    更新日期:2018-09-01 00:00:00

  • Spinal anesthesia for inguinal hernia repair in infants: a feasible and safe method even in emergency cases.

    abstract:BACKGROUND:Inguinal hernia repair is the most frequently performed surgical procedure in infants and children. Especially in premature infants, prevalence reaches up to 30% in coincidence with high rates of incarceration during the first year of life. These infants carry an increased risk of complications due to genera...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-014-3590-y

    authors: Lambertz A,Schälte G,Winter J,Röth A,Busch D,Ulmer TF,Steinau G,Neumann UP,Klink CD

    更新日期:2014-10-01 00:00:00

  • Evaluation of the intraoperative risk factors for esophageal anastomotic complications after primary repair of esophageal atresia with tracheoesophageal fistula.

    abstract:PURPOSE:The aim of this study is to identify the risk factors for esophageal anastomotic stricture (EAS) and/or anastomotic leakage (EAL) after primary repair of esophageal atresia with tracheoesophageal fistula (EA/TEF) in infants. METHODS:A retrospective chart review of 52 patients with congenital EA/TEF between Jan...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-016-3931-0

    authors: Okata Y,Maeda K,Bitoh Y,Mishima Y,Tamaki A,Morita K,Endo K,Hisamatsu C,Fukuzawa H,Yokoi A

    更新日期:2016-09-01 00:00:00

  • Postoperative decrease in plasma acyl ghrelin levels after pediatric living donor liver transplantation in association with hepatic damage due to ischemia and reperfusion injury.

    abstract:PURPOSE:Ghrelin was recently reported to promote recovery from hepatic injury. We hypothesized that it could also be associated with clinical recovery of the transplanted liver from ischemia and reperfusion injury. Our aims were to investigate perioperative ghrelin changes following pediatric living donor liver transpl...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-019-04463-8

    authors: Zenitani M,Hosoda H,Kodama T,Saka R,Takama Y,Ueno T,Tazuke Y,Kangawa K,Oue T,Okuyama H

    更新日期:2019-06-01 00:00:00

  • Life-threatening respiratory distress in a neonate with a pericardial cyst.

    abstract::Our case report details the clinical course and management of a neonate with acute life-threatening respiratory distress presenting soon after birth. She needed intubation and ventilation. A pericardial cyst was diagnosed after a CT scan and 2D echo investigation. As a temporizing procedure the fluid was tapped and th...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-003-0970-0

    authors: Upadhyaya M,Jaffer M

    更新日期:2003-11-01 00:00:00

  • Cost-effectiveness of neonatal surgery: first greeted with scepticism, now increasingly accepted.

    abstract::Mortality rates in neonatal surgery have dropped markedly, illustrating the enormous progress made. Yet, new questions have arisen. To mention one, health care budgets have tightened. It follows that the effects of medical interventions should be weighted against their costs. As evidence was particularly sparse, we se...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审

    doi:10.1007/s00383-007-2045-0

    authors: Poley MJ,Brouwer WB,Busschbach JJ,Hazebroek FW,Tibboel D,Rutten FF,Molenaar JC

    更新日期:2008-02-01 00:00:00

  • Diagnostic and therapeutic approach to multiple endocrine neoplasia type 2B in pediatric patients.

    abstract::Multiple endocrine neoplasia (MEN) 2B is a hereditary syndrome including medullary thyroid carcinoma (MTC), pheochromocytoma, gastrointestinal (GI) disorders, marfanoid facies, and multiple ganglioneuromas. MTC is the major cause of mortality, and often appears during the 1st decade of life. RET proto-oncogene mutatio...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-002-0824-1

    authors: Torre M,Martucciello G,Ceccherini I,Lerone M,Aicardi M,Gambini C,Jasonni V

    更新日期:2002-09-01 00:00:00

  • The laparoscopic spectrum of inguinal hernias and their recurrences.

    abstract::In a retrospective study, intraoperative photos and video documentations of 884 children demonstrate that inguinal hernias and their recurrences are aspects of a full spectrum, which ranges from fully closed internal inguinal rings (IIR) and small openings to all-the way-down-into-the-scrotum open processus; 92% of th...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-007-2018-3

    authors: Schier F

    更新日期:2007-12-01 00:00:00

  • Intraabdominal desmoplastic small round cell tumour.

    abstract::Desmoplastic small round cell tumour (DSRCT) is an extremely rare neoplasm. Adolescent males and young adults are most frequently affected. It is highly malignant, with only 29% of patients surviving up to 3 years. This paper documents two cases, one of which, at 4 years old, is the second youngest case documented. Ca...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章

    doi:10.1007/s00383-005-1401-1

    authors: Mingo L,Seguel F,Rollán V

    更新日期:2005-04-01 00:00:00