Abstract：
PURPOSE:Biliary atresia (BA) is characterized by progressive inflammation of the biliary system. This inflammation persists and causes liver fibrosis, although jaundice disappears after Kasai portoenterostomy (KP). We aimed to confirm whether the oral administration of eicosapentaenoic acid (EPA) suppresses liver fibrosis in postoperative patients with BA. METHODS:We reviewed patients who underwent laparoscopic KP (lapKP) between January 2014 and September 2017. From December 2016, 30 mg/kg/day of EPA was orally administered to patients who opted to take medicine (EPA group). Patients who did not receive EPA were assigned to the non-EPA group. Mac-2 binding protein sugar chain modified isomer (M2BPGi) and hyaluronic acid (HA) levels were compared between the two groups in patients showing disappearance of jaundice at 6 months after the first lapKP. RESULTS:Seventeen patients in the non-EPA group and 11 in the EPA group were enrolled. At 6 months after the first lapKP, 10 patients in the non-EPA group and six in the EPA group were without jaundice. M2BPGi and HA levels were significantly lower in the EPA group. CONCLUSIONS:Liver fibrosis was suppressed in patients without jaundice 6 months after lapKP, who were administered EPA. We believe that periductular inflammation was alleviated by EPA supplementation.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Sumida W,Uchida H,Tainaka T,Shirota C,Hinoki A,Kato T,Yokota K,Oshima K,Shirotuki R,Chiba K,Tanaka Ydoi
10.1007/s00383-018-4313-6subject
Has Abstractpub_date
2018-10-01 00:00:00pages
1059-1063issue
10eissn
0179-0358issn
1437-9813pii
10.1007/s00383-018-4313-6journal_volume
34pub_type
杂志文章abstract：PURPOSE:We evaluated the effectiveness of prophylactic mesenteric lymphatic ligation in preventing iatrogenic chylous fistulae in abdominal neuroblastoma surgery. METHOD:All patients who underwent resection of abdominal neuroblastoma between years 2002 and 2013 were included. A change in surgical strategy commenced fr...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3581-z
更新日期：2014-10-01 00:00:00
abstract：:A 45,X/46,Xidic(Y)(q11.2) mosaicism was found in a 4-year-old boy. The clinical appearance was characterized by bilateral cryptorchidism, penoscrotal hypospadias, short penis, and coarctation of the aorta. The latter is the only abnormality also seen in Turner syndrome. A biopsy of the gonads revealed normal prepubert...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050731
更新日期：2000-01-01 00:00:00
abstract：AIM:Although liver abscess (LA) is prevalent worldwide, especially in developing countries, there is a paucity of data regarding the protocol for management of LA in children. The aim of this study was to analyze the outcome of a protocol-based management of pediatric LA from a single institution. MATERIALS AND METHOD...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-4009-8
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:To describe the association of anorectal malformation (ARM) and spinal dysraphism (SD) in terms of impact on the management of SD and embryogenetic implications. METHODS:Patients with SD associated with (A) or without (B) ARM were included. The two groups were further divided into operated on (A1/B1) or not (A...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-017-4104-5
更新日期：2017-08-01 00:00:00
abstract：:Premature male ischiopagus tetrapus twins weighing 2.2 kg were born unexpectedly. They required initial ventilation for respiratory distress syndrome and an emergency laparotomy for intestinal obstruction at 10 days of age. At 8 months of age, formal separation was carried out. Primary skin closure was possible withou...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01372144
更新日期：1997-04-01 00:00:00
abstract：PURPOSE:The aim of the present study was to review the complications and growth after proctocolectomy and ileal J-pouch anal anastomosis (IPAA) in pediatric ulcerative colitis (UC) patients receiving prolonged steroid therapy. PATIENTS AND METHODS:We experienced 209 patients with UC who received IPAA between September...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-010-2577-6
更新日期：2010-04-01 00:00:00
abstract：PURPOSE:With the widespread use of the obstetrical ultrasound, identification of a fetal suprarenal mass has become more common. Most of these masses prove to be congenital neuroblastomas (CNB), but the diagnosis is often confused with other benign lesions and the postnatal management remains to be controversial. METH...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2531-7
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:Intestinal perforation (IP) is a fatal complication in extremely low birth weight infants (ELBWI). We started administrating enteral miconazole (MCZ) to ELBWI in 2002. Since then, the incidence of IP has significantly decreased. The aim of this study was to elucidate the prophylactic effect of MCZ for the treat...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-3946-6
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:For a definitive diagnosis of congenital solitary kidney, renal scintigraphy is suggested as being the gold standard of ruling out ectopic functioning renal tissue, possibly missed by ultrasound. The aim of our study was to test ultrasonography precision in comparison with renal scintigraphy on a larger coho...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-019-04478-1
更新日期：2019-06-01 00:00:00
abstract：:Nonoperative management is acceptable treatment for minor pancreatic injuries. However, management of major pancreatic duct injury in children remains controversial. We present our experience in treating isolated pancreatic duct injury. We describe the cases of three male patients treated for complete pancreatic duct ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3570-2
更新日期：2014-09-01 00:00:00
abstract：:This review gives an overview of the disease spectrum of congenital diaphragmatic hernia (CDH). Etiological factors, prenatal predictors of survival, new treatment strategies and long-term morbidity are described. Early recognition of problems and improvement of treatment strategies in CDH patients may increase surviv...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-009-2425-8
更新日期：2009-09-01 00:00:00
abstract：:Various options are available for the surgical treatment of meconium ileus (MI). This paper examines the use of resection and primary anastomosis as the favoured option for the treatment of complicated meconium ileus. This was a retrospective study. All patients (13 children) with MI treated with primary resection and...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-2020-9
更新日期：2007-11-01 00:00:00
abstract：BACKGROUND:Pediatric surgeons and patient organisations agree that fewer centers for anorectal malformations with larger patient numbers are essential to reach better treatment. The European Union transacts a political process which aims to realize such centers of expertise for a multitude of rare diseases. All the cen...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3752-6
更新日期：2015-08-01 00:00:00
abstract：:Retrocaval ureter is a relatively rare anomaly that usually manifests in the third or fourth decades. Symptoms are due to ureteric obstruction, either extrinsic by the abnormal inferior vena cava (IVC), or intrinsic ureteric hypoplasia. Surgery is needed for symptomatic cases and involves transection and relocation of...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-003-1038-x
更新日期：2004-02-01 00:00:00
abstract：INTRODUCTION:Hepatoportoenterostomy (HPE) with the Kasai procedure is the treatment of choice for biliary atresia (BA) as the initial surgery. However, the appropriate level of dissection level of the fibrous cone (FC) of the porta hepatis (PH) is frequently unclear, and the procedure sometimes results in unsuccessful ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3799-4
更新日期：2015-12-01 00:00:00
abstract：:Hirschsprung's disease (HD) in Down's syndrome (DS) patients is stated to have a worse outcome than HD alone. In our study we reviewed the immediate and long-term outcomes of these children and questioned whether DS should influence the operative management. Data were collected on all children with HD (including total...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1617-0
更新日期：2006-02-01 00:00:00
abstract：INTRODUCTION:This review aims to (1) assess the breadth of pediatric orthopaedic research in low- and middle-income countries (LMICs) and (2) determine the impact of academic collaboration (an LMIC and a non-LMIC investigator) in published LMIC research. METHODS:Pediatric orthopaedic clinical studies conducted in LMIC...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-018-4412-4
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:Radiologically inserted gastrojejunal tubes (RGJ) and surgical jejunostomy (SJ) are established modes of jejunal feeding. The aim of the study is to review nutritional outcomes, complications and the practical consideration to enable patients and carers to make informed choice. METHODS:Retrospective review of ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4303-8
更新日期：2018-09-01 00:00:00
abstract：:We present the results of a 6-year review of appendicitis. In the event of diagnostic doubt, a policy of active observation was instituted. This review endorses the validity of such a policy, indicating that it does not expose patients to increased morbidity. Data were collected prospectively over a 6-year period on 1...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000483
更新日期：2001-03-01 00:00:00
abstract：:To categorize variant persistent müllerian-duct derivatives (MDD) in males and determine their related clinical presentations for further management, five male patients with retained MDDs from abnormal müllerian remnants were studied. They comprised one patient with persistent müllerian-duct syndrome, one with transve...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0718-2
更新日期：2002-09-01 00:00:00
abstract：:The aim of this study was to determine the effects of a synthetic serine protease inhibitor, gabexate mesilate (GM), in rats with ischemia-reperfusion (I-R) damage due to unilateral testicular torsion. Thirty male Sprague-Dawley rats were separated into three groups, each containing ten rats. A sham operation was perf...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1667-y
更新日期：2006-05-01 00:00:00
abstract：:Minimally invasive surgery (MIS) for cancer patients has become widely accepted in general surgery, however, it has not completely replaced the standard open operative procedures in pediatric oncology. The aim of this study was to evaluate the host relationship following MIS in a murine model of retroperitoneal neurob...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050271
更新日期：1998-03-01 00:00:00
abstract：:An infant with a large-bowel obstruction due to Salmonella B enterocolitis is presented. The clinical and radiologic findings were suggestive of Hirschsprung's disease with total colonic aganglionosis. Due to further deterioration, an ileostomy was performed. Pathologic examination disclosed ganglia in the colon. At l...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003839900332
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Cervicovaginal atresia is a rare Mullerian anomaly. The management of cervicovaginal atresia has evolved from historical recommendations of hysterectomy to various reconstructive procedures more recently. The latter carries a risk of significant morbidity and unknown fertility. We present our experience in t...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3550-6
更新日期：2014-10-01 00:00:00
abstract：:Nine babies with pure oesophageal atresia were treated in our institution in the years 1979-1996. All received a feeding gastrostomy as their initial operation. After initiation of gastrostomy feeds seven (78%) developed gastric complications, including two posterior gastric perforations (one fatal). We propose that t...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050640
更新日期：1999-01-01 00:00:00
abstract：AIM:To share our experience in ovary-sparing surgery for teratomas in children. PATIENTS AND METHODS:The medical records of nine patients (mean age of 11.2 years, r 6-15 years) who had undergone ovary-sparing surgery for teratoma were analyzed retrospectively. Mean duration for follow-up was 29.5 months (r 15-75 month...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-012-3228-x
更新日期：2013-03-01 00:00:00
abstract：:A new instrument for suction rectal biopsy in infants suspected of having Hirschsprung's disease is described that can be completely dismantled, physically cleaned, lubricated, and heat-sterilised. These attributes are new and are absolutely critical today. The instrument has been used in 60 patients (ca. 180 biopsies...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01194812
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVE:Several procedures have been described for repair of distal hypospadias. However, these are not without any complications. Corpus spongiosum advancement is a new technique employed in our patients for distal hypospadias repair with excellent clinical outcome and no post-operative complications. PATIENTS AND ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-013-3292-x
更新日期：2013-06-01 00:00:00
abstract：:Glicentin, the main component of enteroglucagon, has trophic effects on intestinal mucosa. It may also have an inhibitory effect on extraintestinal invasion of enteric bacteria. We have established an in vitro bioassay system for determining the effects of recombinant human glicentin on bacterial internalization by co...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1895-9
更新日期：2007-06-01 00:00:00
abstract：PURPOSE:Surgery of the inguinal canal is very common in infancy. Occasionally, injury of the bladder may occur with severe consequences. The aim of this paper was to warn young surgeons of this serious complication. METHODS:During the last 2 years, we observed four cases of bladder injury following surgery on inguinal...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-010-2707-1
更新日期：2010-12-01 00:00:00
