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Safety and efficacy of mucous fistula refeeding in low-birth-weight infants with enterostomies.

Abstract：

PURPOSE:To investigate the safety and efficacy of mucous fistula refeeding (MFR) in low-birth-weight infants. METHODS:Between December 2006 and December 2018, medical records of low-birth-weight infants who underwent small bowel enterostomy formation in the neonatal period and subsequent stoma closure at our institution were retrospectively reviewed. Patients were assigned to "refeeding" (RF) and "non-refeeding" (NRF) groups, which were compared for patient characteristics and clinical outcomes. We also cultured the proximal stoma output over time in the RF group and reviewed changes in the flora to evaluate the safety of refeeding. RESULTS:In the RF group, compared with that before refeeding, there was significantly more rapid weight gain after refeeding (17.7 vs 10.6 g/day; P = 0.002). Median total time of parenteral nutrition (PN) was 25 and 87 days in the RF and NRF groups, respectively (P = 0.001). The number of patients who developed PN-associated liver disease (PNALD) was smaller in the RF group (P = 0.12). No complications of MFR were noted and no pathogenic bacteria were cultured. CONCLUSION:MFR was able to diminish the need for PN, which potentially decreased the incidence of PNALD, and was safe as there were no complications of the refeeding process.

journal_name

Pediatr Surg Int

journal_title

Pediatric surgery international

authors

Yabe K,Kouchi K,Takenouchi A,Matsuoka A,Korai T,Nakata C

doi

10.1007/s00383-019-04533-x

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

1101-1107

issue

10

eissn

0179-0358

issn

1437-9813

pii

10.1007/s00383-019-04533-x

journal_volume

35

pub_type

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