Abstract：
:The intrinsic innervation of the developing gut has long been a subject of investigation, but little is known regarding that of the embryonic cloaca. The cloaca, like the rest of the gastrointestinal tract, is intrinsically innervated by the enteric nervous system. Nitrergic neurons and fibres make up a large part of this system, thus, their distribution provides us with a useful insight into its development. Cloacal and colorectal tissue specimens were removed from chick embryos at embryonic days 11 (E11), E15 and E19. NADPH-diaphorase (NADPH-d) histochemistry was carried out using whole mount tissue preparations. Ganglia density, the number of NADPH-d-positive cells per ganglia in the myenteric plexus and cell size were calculated and statistical analysis was performed to compare both regions of the gut (P<0.001). There were significant differences in the ganglia density in the cloaca compared to the colorectum at E11 (P<0.05) and E15 (P<0.01), with the colorectum having a much denser network. In both the cloaca and the colorectum, ganglia density significantly decreased with age (P<0.001), while significant differences were observed in the number of NADPH-d-positive cells per ganglia in both regions through development. Total cell size was similar in both the cloaca and colorectum at each stage and increased in both regions through development, predominantly due to an increase in the cytoplasm. Results reveal striking differences in innervation between the chick embryo cloaca and colorectum. The sparse network of innervation evident within the cloaca in contrast to the dense network within the colorectum emphasizes the individuality of both regions. These results highlight the need for a further in-depth analysis of the enteric nervous system's development within the embryonic cloaca.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
O'Donnell AM,Bannigan J,Puri Pdoi
10.1007/s00383-005-1590-7subject
Has Abstractpub_date
2006-01-01 00:00:00pages
90-4issue
1eissn
0179-0358issn
1437-9813journal_volume
22pub_type
杂志文章abstract：PURPOSE:Bicycling is a well-liked sporting activity in which many children participate, and bicycle accidents are one of the most common causes of abdominal injuries in children. We evaluated the characteristics and outcomes of abdominal injuries due to bicycle accidents in children. PATIENTS AND METHODS:This study wa...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-013-3279-7
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:Gastrostomy tube placement is one of the most commonly performed pediatric surgical procedures and discharge is possible as early as the first postoperative day with early initiation of feeds postoperatively. We examined a national database to determine hospital length of stay (LOS) after elective laparoscopic ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-019-04472-7
更新日期：2019-06-01 00:00:00
abstract：:We report a rare case of massive haematochezia due to hookworm infestation that required two laparotomies before the cause of bleeding could be diagnosed. The need to consider this parasite as a possible cause of gut bleeding in endemic countries is stressed, as early recognition may avoid unnecessary investigations a...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00497827
更新日期：1996-06-01 00:00:00
abstract：PURPOSE:The purpose of this study was to test the susceptibility of human hepatoblastoma and neuroblastoma cells to photodynamic diagnostics (PDD) and photodynamic therapy (PDT) using 5-aminolevulinic acid (5-ALA) as a photosensitizer. METHODS:Cell cultures of human hepatoblastoma (HuH6) and neuroblastoma (MHH-NB-11) ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-008-2275-9
更新日期：2008-12-01 00:00:00
abstract：:Umbilical hernias occur frequently in children but complications are very rare and thus surgery is not routinely indicated. In this literature review, we report 19 cases of spontaneous evisceration of abdominal contents through umbilical hernias. Precipitating causes included umbilical ulceration or sepsis, crying, re...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-012-3076-8
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:Fetal extraperitoneal rectal perforation (FERP) is an extremely rare entity. The objective of this report is to review the available literature on this condition and to add our experience with four additional cases managed at our institution. METHODS:A literature search was performed for journal articles addre...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-019-04514-0
更新日期：2019-09-01 00:00:00
abstract：INTRODUCTION:An experimental study was conducted to investigate the effects of erythropoietin on the acute phase of esophageal burn damage induced by sodium hydroxide. MATERIALS AND METHODS:A standard esophageal alkaline burn was produced by the application of 10% sodium hydroxide to the distal esophagus in an in vivo...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2480-1
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND/PURPOSE:To determine the frequency and characteristics of suspected cow's milk protein allergy (CMPA) in infants with gastroschisis and response to change in milk. METHODS:A retrospective cohort study of 111 consecutive infants with gastroschisis. RESULTS:64 episodes suggesting non-IgE-mediated CMPA occurr...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3664-5
更新日期：2015-03-01 00:00:00
abstract：:The most popular techniques for repairing large diaphragmatic defects involve the use of synthetic patches. We present an alternative approach using living tissue. We reviewed our cases of congenital diaphragmatic hernia (CDH) diagnosed within the first 24 h of life from 1991 to 2003. Toldt's fascia (TF) flap was used...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1267-7
更新日期：2005-01-01 00:00:00
abstract：:A retrospective study of all cases (n = 21) of congenital lobar emphysema (CLE) treated at the Royal Hospital, Muscat, from September 1988 to August 1999 was performed. The presentation, diagnosis, treatment, and outcome are reviewed. All 21 patients were nonwhite. Thirteen had left-upper-lobe, 7 right-middle-lobe, an...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000506
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVES:This study reviews the results of our previously described modification of the minimally invasive (Nuss) procedure for correction of pectus excavatum. It utilizes a subxyphoid incision with central fixation to maximize safe bar passage and minimize bar displacement. METHODS:Consecutive patients corrected wi...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-017-4195-z
更新日期：2018-01-01 00:00:00
abstract：:Interposing vascularized flaps between urethra and skin sutures is recommended in hypospadias surgery to decrease the rate of urethrocutaneous fistula. For this purpose nine patients with failed results after at least one hypospadias surgery and with insufficient foreskin were included in the study. Tubularized incise...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-003-0989-2
更新日期：2003-11-01 00:00:00
abstract：:Glicentin, the main component of enteroglucagon, has trophic effects on intestinal mucosa. It may also have an inhibitory effect on extraintestinal invasion of enteric bacteria. We have established an in vitro bioassay system for determining the effects of recombinant human glicentin on bacterial internalization by co...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1895-9
更新日期：2007-06-01 00:00:00
abstract：:To determine the long-term outcome of congenital cystic adenomatoid malformation (CCAM), the records of all patients with CCAM treated in three Hungarian paediatric surgical centers between 1977 and 1996 were reviewed. Patients were followed for up to 20 years following diagnosis and treatment. In 20 patients CCAM was...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050593
更新日期：1999-07-01 00:00:00
abstract：INTRODUCTION:Applicants in the NRMP for pediatric surgery have little objective data available regarding factors predicting successful matching. We analyzed data from applicants at our institution to attempt to identify parameters correlated with three outcomes: successfully matching, or attaining either a top ten or t...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2912-6
更新日期：2011-11-01 00:00:00
abstract：:Parathyroid carcinoma is unusual and its intrathyroidal variant is extremely rare. Therefore, few cases have been reported to describe a case of parathyroid carcinoma located inside the thyroid gland. The case corresponds to a 14-year-old girl who came to the office with a severe osteoarticular disease, depression, ca...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2904-6
更新日期：2011-12-01 00:00:00
abstract：:This study deals with the advancement process of neuroblastoma through clinical observations and circulating tumor cell exploration. Clinical feature, tumor biology, and circulating tumor cell detected by the previously described polymerase chain reaction (PCR) method were analyzed in 31 patients with advanced neurobl...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1503-9
更新日期：2005-11-01 00:00:00
abstract：INTRODUCTION:Recent advances in laparoscopic surgery as well as increasing experience with these techniques have led to the selection of laparoscopic surgery for hemi/partial nephroureterectomy in children with a non/poorly functioning moiety in a duplex kidney. There is very little data on the long term follow-up of s...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2883-7
更新日期：2011-07-01 00:00:00
abstract：PURPOSE:With the widespread use of the obstetrical ultrasound, identification of a fetal suprarenal mass has become more common. Most of these masses prove to be congenital neuroblastomas (CNB), but the diagnosis is often confused with other benign lesions and the postnatal management remains to be controversial. METH...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2531-7
更新日期：2010-03-01 00:00:00
abstract：:Congenital pouch colon, a variant of anorectal malformation, is a rare anomaly with a high incidence in North India and although the anatomy and diagnostic features have been well described, the surgical treatment continues to be challenging. This report describes the complications following a less preferred but often...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1623-2
更新日期：2006-05-01 00:00:00
abstract：:Congenital pyloric atresia (CPA) is a very rare condition that was first described by Calder in 1749. Commonly, CPA occurs as an isolated lesion, which has an excellent prognosis, but it can also be seen in association with other malformations, which can have a negative impact on the final outcome. The medical records...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1903-0
更新日期：2007-06-01 00:00:00
abstract：PURPOSE:To study the effects of frenulotomy on nipple pain, latch and the success in exclusive breastfeeding (EBF) at 3-month follow-up. METHODS:A prospective cross-sectional study of 328 mother-infant pairs with both tongue-tie and breastfeeding problems was performed. Nipple pain and latch were evaluated using numer...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-3952-8
更新日期：2016-10-01 00:00:00
abstract：AIM:To share our experience in ovary-sparing surgery for teratomas in children. PATIENTS AND METHODS:The medical records of nine patients (mean age of 11.2 years, r 6-15 years) who had undergone ovary-sparing surgery for teratoma were analyzed retrospectively. Mean duration for follow-up was 29.5 months (r 15-75 month...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-012-3228-x
更新日期：2013-03-01 00:00:00
abstract：PURPOSE:The loss of normal anatomic barriers in neonates with congenital diaphragmatic hernia (CDH) can predispose children to gastroesophageal reflux (GER). In an attempt to improve post-operative feeding, we have added a modified anterior fundoplication to restore natural gastric and esophageal positioning. METHODS:...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2411-1
更新日期：2009-08-01 00:00:00
abstract：:With widespread use of antenatal ultrasound, an increasing number of urinary-tract lesions are being detected, and the clinician is called upon to make management decisions. Parenchymal lesions of the kidney pose a special challenge because of the associated risk of the occurrence of malignancy. A case of an antenatal...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0833-0
更新日期：2003-04-01 00:00:00
abstract：PURPOSE:We have retrospectively evaluated all patients who underwent endoscopic puncture (EP) of ureterocele over the last 26 years with special reference to the need in the second intervention and disease-free status. METHODS:78 (69%) of the 112 patients following EP and completed follow-up were included. 51 (65%) we...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4258-9
更新日期：2018-05-01 00:00:00
abstract：:An infant developed massive lower gastrointestinal haemorrhage secondary to necrotising enterocolitis after cardiac surgery. The haemorrhage was only controlled following a colectomy. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050613
更新日期：1999-07-01 00:00:00
abstract：:Congenital arteriovenous fistulas are a rare cause of neck mass in children, but should be considered in the differential diagnosis of paediatric patients presenting with pulsatile neck masses even when there is no history of trauma. Balloon embolisation is the treatment of choice because of the high risk of surgical ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2918-0
更新日期：2011-12-01 00:00:00
abstract：:A total of four patients with communicating bronchopulmonary foregut malformation were treated surgically at Kobe Children's Hospital between 1993 and 2004. Of these, three patients displayed congenital tracheobronchial stenosis and developed life-threatening respiratory distress soon after birth. In each case, anomal...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1520-8
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND/AIM:Esophageal dilatation, gastroesophageal reflux, and intestinal obstruction have been demonstrated in CDH survivors. Abnormal esophageal and intestinal innervations were recently found in rats and babies with this disease. Our aim was to further characterize these malformations in embryos and fetal rats e...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-010-2788-x
更新日期：2011-02-01 00:00:00
