Abstract:
:Non-operative management of gastroschisis also known as plastic closure (PC) has been described as an alternative to conventional primary operative closure (POC) or staged silo closure (SSC). The aim of this study was to compare these techniques in neonates with gastroschisis. A retrospective review of neonates with gastroschisis who underwent PC was undertaken. The minimum follow-up was 1 year. Premature neonates (<35 weeks) and those with intestinal atresia or multiple congenital anomalies were excluded. Frequency matching of PC cases with two control groups with either POC or SSC was performed on 1:1 ratio, based on gestational age and birth weight. Statistical analysis using univariate analysis was performed. Three groups were assembled: PC, POC and SSC (n = 33). Median follow-up was 1,198 days. Groups were comparable with regard to: time to first feed, time to full enteral feeding, frequency of vascular access related infections, ventilation time, NICU LOS (length of stay) and hospital LOS. There was no difference observed in surgical complications. Almost all neonates in the PC group developed an umbilical hernia (83.8%). Umbilical hernias were highly associated with PC compared to the other two groups P = 0.001. To date only one patient has had to have an operative repair of the umbilical hernia in the PC group. Plastic closure is safe and comparable to conventional closure techniques. However, PC is associated with the development of more umbilical hernias. The natural history of these hernias remains to be defined.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Bonnard A,Zamakhshary M,de Silva N,Gerstle JTdoi
10.1007/s00383-008-2153-5subject
Has Abstractpub_date
2008-07-01 00:00:00pages
767-71issue
7eissn
0179-0358issn
1437-9813journal_volume
24pub_type
杂志文章abstract:BACKGROUND:Intestinal adaptation in short bowel syndrome (SBS) consists of increased epithelial cells (ECs) proliferation as well as apoptosis. Angiotensin-converting enzyme (ACE) has been shown to regulate ECs apoptosis. In this study, we investigated the effect of ACE inhibition on intestinal adaptation after small b...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3075-9
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:There are many advantages of a SMOF emulsion (SMOF-lipid), such as liver-protective properties and anti-inflammatory effects. The objective of this study was to compare the clinical outcomes of SMOF-lipid with medium-chain triglycerides (MCT) /long-chain triglycerides (LCT) in infants after intestinal surger...
journal_title:Pediatric surgery international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00383-018-4422-2
更新日期:2019-03-01 00:00:00
abstract::The advances in science have resulted in the emergence of nanotechnology, which deals with the design and use of tools and devices of size 1-100 nm. The application of nanotechnologies to medicine is thus termed nanomedicine. Significant research has been focused on this new and exciting field and this review article ...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-012-3162-y
更新日期:2012-10-01 00:00:00
abstract:AIM:We assessed continence after scope-assisted anorectovaginoplasty (SARVP) for female anorectal malformation (FARM). METHODS:Five FARM cases were assessed; cases 1 and 2: cloacal malformation; case 3: urogenital sinus, and rectovestibular fistula (RF); case 4: RF, absent vagina, and sacral anomaly; case 5: covered c...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3141-3
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:Bone morphogenetic proteins (BMPs) are a group of growth factors that are implicated in intestinal growth, morphogenesis, differentiation, and homeostasis. The role of the BMP signaling cascade in stimulation of cell proliferation after massive small bowel resection is unknown. The purpose of this study was to ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3829-2
更新日期:2016-02-01 00:00:00
abstract::CHARGE association and DiGeorge syndrome (DGS) rarely occur together and only eight cases have been reported in the English literature. Two were associated with esophageal atresia (EA) and severe congenital heart anomalies. We report a third case of EA with tracheoesophageal fistula (EA-TEF) associated with coarctatio...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-008-2222-9
更新日期:2008-10-01 00:00:00
abstract::We examined immunohistochemically the expression and localisation of synapse-associated proteins, syntaxin (SNT) and synaptotagmin (STG) in the entire resected specimens of colon obtained at the time of pull-through operation from 15 patients with Hirschsprung's disease (HD) and 6 age-matched controls. Both antibodies...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050408
更新日期:1998-10-01 00:00:00
abstract::Eight children with Morgagni hernia were operated between January 2000 and May 2005. Medical records of the patients were evaluated retrospectively. Ages of the patients were between 3.5 months and 9 years. The diaphragmatic defect was on the right in all patients except one. One patient had bilateral diapragmatic her...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1750-4
更新日期:2006-10-01 00:00:00
abstract:PURPOSE:Laparoscopic-assisted anorectoplasty (LAARP) is a minimally invasive procedure in which the levator ani muscle is left to potentially improve postoperative fecal continence. This study aimed to retrospectively evaluate postoperative complications and long-term outcomes of fecal continence after LAARP and compar...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4323-4
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:Retroperitoneal teratomas (RTs) are rare among germ cell tumors and predominantly occur in infants. RTs are often difficult to manage by perioperative management. In this study, we retrospectively reviewed our series of RTs. METHODS:Seventy patients with germ cell tumors were treated from 1989 to 2015 in our i...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3938-6
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:Laparoscopic Kasai portoenterostomy was reported to be a safe and feasible procedure in infant with biliary atresia. We aimed to investigate the long-term results after laparoscopic portoenterostomy as such data in the literature are lacking. METHODS:Sixteen infants underwent laparoscopic Kasai portoenterostom...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-012-3172-9
更新日期:2012-11-01 00:00:00
abstract::Biliary atresia (BA) is a common cause of infantile cholestasis. Disease progression leads to intra hepaticfibrosis, and thus to the development of PH and EV. Our objective has been to study the relationship between procollagen-III-peptide (PIIIP) and the severity of EV in children with BA after Kasai operation. Child...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830200007
更新日期:2002-01-01 00:00:00
abstract::Accidental ingestion of corrosive substances remains a major health hazard in children. Most infants and children who ingest caustic substances present with very few symptoms or signs. Approximately 40% of caustic substance ingestions result in esophageal injury, but the optimal management of caustic esophageal burns ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1331-3
更新日期:2005-02-01 00:00:00
abstract:PURPOSE:Pediatric surgeons at our institution are often asked by families about a theoretical increased risk of severe common upper respiratory infections in children status post lung resection. No data exist on this topic. We, therefore, aimed to examine the risk of severe respiratory infection in children after pulmo...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-020-04851-5
更新日期:2021-01-10 00:00:00
abstract:PURPOSE:Chronological age has not always been an accurate predictor of gut motility in newborns. We hypothesized that the enteric plexus is immature at birth. We studied whole-mount preparations of the myenteric plexus in pigs from mid-point of gestation to adulthood. METHODS:Distal large bowel whole-mount preparation...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2265-y
更新日期:2008-12-01 00:00:00
abstract::In neonates requiring operation for necrotizing enterocolitis (NEC), the complications due to enterostomy (ES) and the need for another operation to restore continuity have prompted several surgeons to employ primary anastomosis (PA) after resection as the operative strategy of choice. Our objective was to compare pri...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-017-4126-z
更新日期:2017-11-01 00:00:00
abstract::Anterior sagittal anorectoplasty (ASARP) was used for the definitive correction in 107 cases of anovestibular fistula (AVF) between 1996 and 2005. These cases were subjected to three different types of treatment regimes during the same period. Majority of the cases (78) were operated in one stage where postoperatively...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2019-2
更新日期:2007-12-01 00:00:00
abstract::A modified technique of laparoscopic pyloromyotomy was used to treat infantile hypertrophic pyloric stenosis. Introducing a 5-mm periumbilical port for visualization, two stab wounds are made on either side laterally to directly insert 2.7-mm instruments for manipulation. From the left, the stomach is grasped - not th...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050307
更新日期:1998-04-01 00:00:00
abstract::An isolated bowel segment (IBS) is a viable loop of bowel that is completely free of its mesenteric attachments. In this study, omentoenteropexy (OEP) was performed in 5-cm-long IBS of rats in order to provide neovascularization. Thirty-two rats were divided into four groups. After OEP, mesenteric division of the IBSs...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF01076940
更新日期:1997-07-01 00:00:00
abstract:UNLABELLED:Anorectal malformation (ARM) is a group of significant birth defects with geographic variation in incidence, individual phenotypes and regional geographic subtypes occurring in approximately 1:5,000 live births. Anorectal atresia with gross terminal colonic distension in the presence of an absent anal canal ...
journal_title:Pediatric surgery international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00383-013-3346-0
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:To compare integration of bladder acellular matrix (BAM) with the bladder when seeded with mesenchymal stem cells (MSC) and when MSC are injected intravenously (IV). METHODS:MSCs were isolated from bone marrow of EPM-1 Wistar male rats. Female rats were distributed into: Group A-BAM augmentation; Group B-BAM a...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3465-2
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:To report the authors' experience in the management of perforated choledochal cyst with bile peritonitis (PCC) in children. METHODS:Medical records of all children undergoing surgery for PCC at our hospital from May, 2005 to January, 2013 were reviewed. RESULTS:Twenty seven patients were identified, with a me...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3461-6
更新日期:2014-03-01 00:00:00
abstract::Recurrent or chronic abdominal pain can be a challenging problem when conventional diagnostic studies fail to identify the cause. It is estimated that up to one-third of children suffer from abdominal pain, and in this population recurrent pain can be even more challenging. Although recurrent right lower quadrant (RLQ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-005-1632-1
更新日期:2006-03-01 00:00:00
abstract::A total of 235 children, aged between 7 months and 15 years had bronchoscopy on suspicion of foreign body aspiration. The histories of these patients were studied to examine the diagnostic value of symptoms, signs, and chest x-rays, and rate of negative bronchoscopy. The sensitivity of choking and coughing was high (8...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-0965-x
更新日期:2003-08-01 00:00:00
abstract::The factors that affect survival in patients with stage 4 neuroblastoma vary. Several prospective and retrospective studies have provided conflicting conclusions regarding the benefit of combining aggressive chemotherapy with complete surgical resection. We analyzed our experience to evaluate the effect of complete su...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1353-x
更新日期:2005-02-01 00:00:00
abstract::Surgical repair of acquired tracheo-esophageal fistula may result in tracheal stenosis or esophageal stricture. We used fistula with esophageal cuff as flap to repair the tracheal defect. Esophageal repair was performed by rotating ends through 90° in opposite direction. This technique offers excellent repair in a sin...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-014-3498-6
更新日期:2014-05-01 00:00:00
abstract::Single-system ureteral ectopia (UE) encompasses a spectrum of malformations involving the bladder trigone, ureter, and kidney. The clinical presentation is variable, and both diagnostic and therapeutic problems are common. Reduced renal function in these patients may result from primary dysplasia, obstruction, vesicou...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000414
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:To describe a modification of PATIO repair for urethrocutaneous fistula repair and evaluate its outcome. METHODS:We studied 15 boys who underwent modified PATIO repair from Jan 2010 to Sept 2015. Parameters studied included age, type of hypospadias, age at first urethroplasty, hypospadias repair technique, ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-016-3983-1
更新日期:2017-01-01 00:00:00
abstract::This report describes three children, age range 7 weeks to 5 months, who presented with obstructive jaundice secondary to gallstones. Previous Escherichia coli septicaemia and frusemide therapy were predisposing risk factors in two of the patients. All three were successfully treated with cholecystectomy and explorati...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:
更新日期:1997-02-01 00:00:00
abstract:PURPOSE:The loss of normal anatomic barriers in neonates with congenital diaphragmatic hernia (CDH) can predispose children to gastroesophageal reflux (GER). In an attempt to improve post-operative feeding, we have added a modified anterior fundoplication to restore natural gastric and esophageal positioning. METHODS:...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2411-1
更新日期:2009-08-01 00:00:00