Abstract:
:Minimally invasive surgery (MIS) for cancer patients has become widely accepted in general surgery, however, it has not completely replaced the standard open operative procedures in pediatric oncology. The aim of this study was to evaluate the host relationship following MIS in a murine model of retroperitoneal neuroblastoma (NB) Immature, 5- to 7-week-old male A/J mice weighing 18-23 g were inoculated with either C1300 or TBJ NB in the left retroperitoneal space. At 4 days (early stage) or 11 days (late stage) following tumor inoculation, the animals underwent a laparotomy or pneumoperitoneum with carbon dioxide under general inhalational anesthesia. Animal survival, tumor growth, and postoperative changes in body weight were observed. In the model of subcutaneous TBJ NB, distant metastases following the laparotomy or MIS technique were also evaluated. Each surgical group had a sample size > or = 12, and data were statistically analyzed by ANOVA and the chi-square test where appropriate. P < 0.05 was considered to be significant. There were no significant differences in animal survival, tumor growth, or distant metastases among surgical groups in any combination of type and stage of tumor. The only salutary influence of MIS was seen in a model of early-stage NB, where the decrease in body weight on postoperative day 7 was preserved when compared to post-laparotomy weight loss. We conclude that when compared to conventional laparotomy, the MIS access technique does not influence the outcome in a model of retroperitoneal murine NB.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Iwanaka T,Arya G,Ziegler MMdoi
10.1007/s003830050271subject
Has Abstractpub_date
1998-03-01 00:00:00pages
149-53issue
2-3eissn
0179-0358issn
1437-9813journal_volume
13pub_type
杂志文章abstract::The aim of this study is to evaluate the safety and efficacy of the redo transanal endorectal pull-through (TEPT) for patients with persistent symptoms after pull-through for Hirschsprung's disease (HD). Seven children were included in the study, their ages ranged from 2.5 to 6 years (four males and three females). Th...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1837-y
更新日期:2007-02-01 00:00:00
abstract:INTRODUCTION:Management of oesophageal atresia (OA) and trachea-oesophageal fistula (TOF) in babies of low birth weight is challenging especially when associated with other anomalies. Birth weight of <1500 g has previously formed part of a classification system designed to predict outcome, alongside the cardiac status ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3851-4
更新日期:2016-06-01 00:00:00
abstract::A case of retrocecal appendicitis is described in a 6-year-old male child who presented with thigh abscess. The presence of a positive psoas stretch test, feculent discharge, an enteric growth on bacteriological examination, and intraabdominal fluid collection on abdominal ultrasound provided clues to the presence of ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1356-7
更新日期:2005-04-01 00:00:00
abstract::Pseudoexstrophy is a rare variant of the exstrophy/epispadias complex, comprised of the musculoskeletal defects of classic exstrophy but with an intact bladder and urethra. We present a case of a neonate with left-sided gastroschisis and pseudoexstrophy, the first reported combination of these two anomalies. The anoma...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1217-4
更新日期:2004-07-01 00:00:00
abstract::Fetal lambs with diaphragmatic herniae (CDH) created surgically at 73 days' gestation were subjected to three different forms of intrauterine correction: silastic patch correction of the diaphragmatic defect plus an abdominal patch at 101 days gestation; an intrathoracic "silo" at 101 days; and a tracheal "plug" obstr...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00626057
更新日期:1996-10-01 00:00:00
abstract:UNLABELLED:Vascular trauma is uncommon in children but may be complex. Arterial injury in children presents a challenge to the surgeon and may have long-term implications. Children have major advantage of a rich-collateral circulation but are still growing and developing. Decisions about when to operate remain an issue...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-011-3033-y
更新日期:2012-04-01 00:00:00
abstract::The introduction of posterior sagittal anorectoplasty (PSARP) by deVries and Peña in the early 80s has impacted to the treatment of patients with anorectal malformations (ARM). It gained great recognition worldwide in a very short time, and since then, surgeons dealing with the treatment of this complex malformation c...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-020-04629-9
更新日期:2020-04-01 00:00:00
abstract::In a retrospective study, intraoperative photos and video documentations of 884 children demonstrate that inguinal hernias and their recurrences are aspects of a full spectrum, which ranges from fully closed internal inguinal rings (IIR) and small openings to all-the way-down-into-the-scrotum open processus; 92% of th...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-007-2018-3
更新日期:2007-12-01 00:00:00
abstract::Eight children with Morgagni hernia were operated between January 2000 and May 2005. Medical records of the patients were evaluated retrospectively. Ages of the patients were between 3.5 months and 9 years. The diaphragmatic defect was on the right in all patients except one. One patient had bilateral diapragmatic her...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1750-4
更新日期:2006-10-01 00:00:00
abstract::Liver transplantation (LT) for malignancy has had disappointing long-term results due to tumour recurrence. Ex-vivo dissection and auto-transplantation have had poor results when the tumor was obstructing bile ducts. Advances in liver surgery have made extensive liver resection safer, but cases of "unresectable" tumou...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000531
更新日期:2001-07-01 00:00:00
abstract::Retrocaval ureter is a relatively rare anomaly that usually manifests in the third or fourth decades. Symptoms are due to ureteric obstruction, either extrinsic by the abnormal inferior vena cava (IVC), or intrinsic ureteric hypoplasia. Surgery is needed for symptomatic cases and involves transection and relocation of...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-003-1038-x
更新日期:2004-02-01 00:00:00
abstract:PURPOSE:Laparoscopic-assisted anorectoplasty (LAARP) is a minimally invasive procedure in which the levator ani muscle is left to potentially improve postoperative fecal continence. This study aimed to retrospectively evaluate postoperative complications and long-term outcomes of fecal continence after LAARP and compar...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-018-4323-4
更新日期:2018-10-01 00:00:00
abstract::Interstitial cells of Cajal (ICCs) have been reported to play the role of a pacemaker in regulating bowel motility. The relationship between neurons and ICCs, however, remains unclear. Hirschsprung's disease (HD) is an ideal model for investigating this relationship. The operated specimens obtained from 6 short and 3 ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0931-z
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:Pediatric surgeons and patient organisations agree that fewer centers for anorectal malformations with larger patient numbers are essential to reach better treatment. The European Union transacts a political process which aims to realize such centers of expertise for a multitude of rare diseases. All the cen...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-015-3752-6
更新日期:2015-08-01 00:00:00
abstract::Polyorchidism is defined as the presence of more than two testes. We report the case of a 3-year-old boy and review the embryology and surgical management of the condition. ...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050247
更新日期:1998-01-01 00:00:00
abstract::The purpose of this report was to analyze the patients requiring preoperative extracorporeal membrane oxygenation (ECMO) as the most critical group of patients with congenital diaphragmatic hernia (CDH) and to identify any special features. Over the past 11 years, out of 72 neonates with CDH admitted before 24 h of ag...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830050428
更新日期:1998-11-01 00:00:00
abstract::We report a rare case of massive haematochezia due to hookworm infestation that required two laparotomies before the cause of bleeding could be diagnosed. The need to consider this parasite as a possible cause of gut bleeding in endemic countries is stressed, as early recognition may avoid unnecessary investigations a...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00497827
更新日期:1996-06-01 00:00:00
abstract::Children with pyometrocolpos due to distal vaginal atresia may present as acutely ill, with severe obstructive uropathy and septicemia. In such patients the clinical course is markedly improved by urgent drainage of the infected cystic mass, and a temporary drainage procedure is required to allow local findings of inf...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-004-1323-3
更新日期:2005-03-01 00:00:00
abstract::Around the 30th week of gestation, patients with gastroschisis (GS) develop chronic inflammatory reactions on the serosal surface of the eventrated loops of intestine that lead to severe hyperfibrinogenemia and hypercoagulability, particularly if they are born prematurely. This result was found on comparison of coagul...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/BF00183729
更新日期:1996-03-01 00:00:00
abstract:INTRODUCTION:We assessed the impact of intestinal transplantation on Japanese pediatric patients with intestinal failure with data from the Japanese intestinal transplant registry. METHODS:Standardized forms were sent to all known intestinal transplantation programs, requesting information on transplants performed bet...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-013-3392-7
更新日期:2013-10-01 00:00:00
abstract::The aim of this study was to determine the effects of a synthetic serine protease inhibitor, gabexate mesilate (GM), in rats with ischemia-reperfusion (I-R) damage due to unilateral testicular torsion. Thirty male Sprague-Dawley rats were separated into three groups, each containing ten rats. A sham operation was perf...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1667-y
更新日期:2006-05-01 00:00:00
abstract::To determine the incidence of cystic fibrosis (CF) in neonates with intestinal obstruction (NIO) secondary to meconium ileus (MI), jejunoileal atresia (JA), meconium plug syndrome (MPS), volvulus (V), and meconium peritonitis (MP) and analyze the correlation of ultrasonographic (US) signs with CF in NIO with a prenata...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-002-0781-8
更新日期:2003-04-01 00:00:00
abstract:UNLABELLED:Necrotizing enterocolitis (NEC) is a serious condition with a high morbidity and mortality commonly affecting premature babies. Data for the impact of the long-term disease burden in developing countries are limited although poor long-term outcome of surgically managed patients has been shown in terms of inc...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-010-2583-8
更新日期:2010-04-01 00:00:00
abstract:INTRODUCTION:No protocol exists for prophylaxis or therapeutic management of peripherally inserted central catheter (PICC) related deep venous thrombosis (DVT) in children. Currently, very few patients are provided prophylaxis for DVT. In this study, we analyzed our current practice of PICC placement to identify the fr...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-013-3259-y
更新日期:2013-05-01 00:00:00
abstract::Hepatogastric fistula secondary to amebic liver abscess is extremely rare. Only three pediatric cases have been reported in the English literature. Percutaneous drainage of abscess along with parenteral metronidazole can prevent the need for extensive surgical intervention. Timely intervention is usually followed by c...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-006-1743-3
更新日期:2006-10-01 00:00:00
abstract::Juvenile papillomatosis (JP) is a rare benign, proliferative breast tumor in children. We observed a 9-year-old girl with a large soft-tissue mass at the lower outer quadrant of the left breast. Ultrasonography showed an ill-defined, inhomogeneous mass with numerous small, hypoechoic areas. The tumor was completely ex...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s003830000462
更新日期:2001-03-01 00:00:00
abstract::In neonates requiring operation for necrotizing enterocolitis (NEC), the complications due to enterostomy (ES) and the need for another operation to restore continuity have prompted several surgeons to employ primary anastomosis (PA) after resection as the operative strategy of choice. Our objective was to compare pri...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-017-4126-z
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:Tracheoesophageal fistula (TEF) is a bellwether for a country's ability to care for sick newborns. We aim to review the existing literature from low- and middle-income countries in regard to management of those newborns and the possible approaches to improve their outcomes. METHODS:A review of the existing Eng...
journal_title:Pediatric surgery international
pub_type: 杂志文章,评审
doi:10.1007/s00383-020-04639-7
更新日期:2020-05-01 00:00:00
abstract::Congenital diaphragmatic hernia (CDH) is accompanied by pulmonary hypoplasia and pulmonary hypertension. Fetal lung growth is dependent on the secretion of lung liquid, which normally is absorbed at partus. The ion channel NKCC-1 is involved in this secretory process, but has recently also been reported to be implicat...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-008-2209-6
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:Partial hepatectomy (PH) can be an inevitable surgical therapy in some conditions, such as hepatic malignancies, trauma or partial liver transplantation. Its capacity for regeneration distinguishes the liver from other essential organs. Regeneration is a complex process involving growth factors, cytokines, tran...
journal_title:Pediatric surgery international
pub_type: 杂志文章
doi:10.1007/s00383-009-2529-1
更新日期:2010-02-01 00:00:00