Abstract：
:Fetal lambs with diaphragmatic herniae (CDH) created surgically at 73 days' gestation were subjected to three different forms of intrauterine correction: silastic patch correction of the diaphragmatic defect plus an abdominal patch at 101 days gestation; an intrathoracic "silo" at 101 days; and a tracheal "plug" obstruction at 101 or 129 days. At 143 days' gestation (term 145-149 days), the lambs were delivered by caesarean section and ventilated for 30 min before undergoing respiratory compliance measurements. These results were compared to those of normal lambs and animals with uncorrected herniae. The total respiratory system compliance values in those groups undergoing corrections were remarkably similar: those with any form of correction had a significant improvement (P < 0.05) compared to those with herniae and no correction (patch = 1.57 = ± 0.182 ml/cm H2O; silo = 1.53 ± 0.179; plug at 101 days = 1.66 ± 0.311; plug at 129 days = 2.00 ± 0,175; without correction = 0.62 ± 0.073). None, however, reached the values of those with normal lungs: 2.72 ± 0.223 (P < 0.05). This improvement in compliance in all corrected groups suggests that fetal tracheal obstruction is as effective as the two more invasive forms of open fetal surgery carried out in this study and, as this procedure lends itself to surgery through a small uterine incision or "minimally invasive" surgery, it may be the procedure of choice to reduce the incidence of preterm labour for those human fetuses undergoing antenatal correction of a CDH.bb.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Ford WD,Cool JC,Parsons D,Martin AJ,Kennedy JD,Lipsett J,Byard RW,Slater AJdoi
10.1007/BF00626057subject
Has Abstractpub_date
1996-10-01 00:00:00pages
524-7issue
8eissn
0179-0358issn
1437-9813journal_volume
11pub_type
杂志文章abstract：PURPOSE:Rapid assessment of volume status in children is often difficult. The purpose of this study was to evaluate the feasibility of surgeon-performed ultrasound to assess volume status in patients with hypertrophic pyloric stenosis. METHODS:Ultrasounds were performed on admission and before operation. The diameters...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-015-3798-5
更新日期：2015-12-01 00:00:00
abstract：:Aim was to describe the challenges faced in the management of bilateral multicystic kidney disease (MCKD). A case of antenatally detected bilateral polycystic disease was referred at 28 weeks of gestation. The patient was advised to continue pregnancy till term and be in regular follow-up. Postnatally, the male baby p...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-007-1962-2
更新日期：2007-08-01 00:00:00
abstract：:Fetal skin wounds heal scarlessly while adult wounds scar. Fetal wound healing occurs in a physiologically hypoxic environment whereas in adult wound healing, cells have to acutely adapt to hypoxia caused by locally impaired blood supply. We examined the expression of hypoxia-inducible factor 1 (HIF-1), a potent trans...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050735
更新日期：2000-01-01 00:00:00
abstract：:High ligation of spermatic vessels (HLSV) and low ligation of spermatic vessels (LLSV) have been described in the surgical treatment of high undescended testis. Testicular capillary blood flow utilizing laser Doppler flowmetry after these maneuvers has not been studied thus far; hence, this study was designed. Thirty ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-003-1018-1
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:There is a shortage of surgeons in Africa, and this shortage is particularly acute in paediatric surgery with most paediatric patients being cared for by general surgeons. The use of information technology to augment teaching in paediatric surgery in Africa is appealing but often unsuccessful due to the cost...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-010-2806-z
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:Cervicovaginal atresia is a rare Mullerian anomaly. The management of cervicovaginal atresia has evolved from historical recommendations of hysterectomy to various reconstructive procedures more recently. The latter carries a risk of significant morbidity and unknown fertility. We present our experience in t...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-014-3550-6
更新日期：2014-10-01 00:00:00
abstract：:Polyorchidism is defined as the presence of more than two testes. We report the case of a 3-year-old boy and review the embryology and surgical management of the condition. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050247
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:There are many advantages of a SMOF emulsion (SMOF-lipid), such as liver-protective properties and anti-inflammatory effects. The objective of this study was to compare the clinical outcomes of SMOF-lipid with medium-chain triglycerides (MCT) /long-chain triglycerides (LCT) in infants after intestinal surger...
journal_title：Pediatric surgery international
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00383-018-4422-2
更新日期：2019-03-01 00:00:00
abstract：:Primary lymphedema of the penis (PLP) is a rare disease. We report a case in a 2-year-old, uncircumcised boy where the uninvolved inner preputial skin was unfurled to cover the penile shaft. The uninvolved inner preputial skin is often elongated, and provides a suture-free cover of sufficient length for the small peni...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000487
更新日期：2001-03-01 00:00:00
abstract：:We reviewed our clinical experience of using a computer-powered right angle linear cutter (CPRALC) for Collis-Nissen fundoplication (CNF) in three children with gastroesophageal reflux (GER) or failed Nissen associated with short esophagus. Case 1 was a 13-month-old female with persistent GER after type-C esophageal a...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-009-2455-2
更新日期：2009-11-01 00:00:00
abstract：:From January 1972 to June 1993, 166 patients with posterior urethral valves (PUV) were treated in our surgical department, 59 with a milder form of PUV (upper urinary tract [UUT] complication rate 29%) and 107 with a severer form (UUT complication rate 96.3%). Only the latter group was studied for long-term (mean 9.3 ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00497807
更新日期：1996-06-01 00:00:00
abstract：:We analyzed the causes and diagnoses, the treatment, short and long-term outcome of a consecutive series of 70 pediatric polytrauma patients. From 1989 to 1996, 70 children (aged 10 months to 16 years, mean 7.4 years) presented with multiple trauma. A follow-up investigation was performed 4.2 years (mean) after the ac...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-003-0954-0
更新日期：2003-08-01 00:00:00
abstract：:Management of stage IV rhabdomyosarcoma comprises systemic chemotherapy with local control by conservative surgery and radiotherapy. Abdominal radiotherapy may lead to radiation enteritis causing such serious morbidity as malabsorption, fistulae or stricture formation. The risk increases with the dose of radiation and...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1490-x
更新日期：2005-09-01 00:00:00
abstract：:A 7-year-old female with a type I choledochal cyst underwent an exploratory laparotomy. A Roux-en-Y choledochojejunostomy was done following cyst excision. The patient was re-explored 8 days later for an anastomotic bile leak and high fever. A round-worm was found obstructing the jejunal lumen at the porta hepatis, re...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050394
更新日期：1998-09-01 00:00:00
abstract：:Repair of giant inguino-scrotal hernia (GISH) in male infants is a difficult operation, even in experienced hands. It requires an immaculate technique to avoid known complications such as tearing of the sac, injury to delicate testicular vessels and dividing of vas deferens. Moreover, a recurrence rate of 9% is noted ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-008-2145-5
更新日期：2008-06-01 00:00:00
abstract：:The first description diaphragmatic hernia appeared in 1575. In 1848, Bochdalek described congenital diaphragmatic hernia (CDH) occurring through a posterolateral defect. Successful surgical treatment of CDH in an infant was first performed in 1902, whereas the first neonate operated within 24 hours of life was report...
journal_title：Pediatric surgery international
pub_type： 历史文章,杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：PURPOSE:To review the effectiveness of the longitudinal intestinal lengthening and tailoring (LILT) and serial transverse enteroplasty (STEP) operations in a cohort of patients with short bowel syndrome (SBS). METHODS:We conducted a retrospective analysis of children with SBS treated at our institution from 2004 until...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-019-04468-3
更新日期：2019-06-01 00:00:00
abstract：:The advances in science have resulted in the emergence of nanotechnology, which deals with the design and use of tools and devices of size 1-100 nm. The application of nanotechnologies to medicine is thus termed nanomedicine. Significant research has been focused on this new and exciting field and this review article ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-012-3162-y
更新日期：2012-10-01 00:00:00
abstract：:In children with severe chronic constipation, abnormal distribution of substance P (SP) and vasoactive intestinal peptide (VIP), which represent excitatory and inhibitory nerves, respectively, has been reported. The normal distribution of these neuropeptides, however, is not well known. The aim of this study was to de...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050438
更新日期：1998-11-01 00:00:00
abstract：:Gastroschisis is traditionally managed by primary closure (PC) or delayed closure after surgical silo placement. Bedside insertion of preformed silos (PFS) and delayed closure has become more widespread, although its benefits remain unclear. To identify differences in outcome of infants managed with PFS compared with ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-2004-9
更新日期：2007-11-01 00:00:00
abstract：:The purpose of this report was to analyze the patients requiring preoperative extracorporeal membrane oxygenation (ECMO) as the most critical group of patients with congenital diaphragmatic hernia (CDH) and to identify any special features. Over the past 11 years, out of 72 neonates with CDH admitted before 24 h of ag...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050428
更新日期：1998-11-01 00:00:00
abstract：PURPOSE:Feeding and systemic hypoxia are major stresses inducing necrotizing enterocolitis (NEC). This study aims to investigate the role of systemic hypoxia in NEC and its effect before and after feeding. METHODS:Neonatal mice were studied in three groups. Control (N = 9): breast feeding; NEC A (N = 8), gavage feedin...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-3997-8
更新日期：2016-12-01 00:00:00
abstract：:With advances in neonatology, there is an increasing need for central vascular access in extremely small (<1,000 g) premature infants. Although the use of peripherally inserted central venous lines have become common practice, surgeons still frequently perform central venous line placements via cut-down in difficult a...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1474-x
更新日期：2005-09-01 00:00:00
abstract：PURPOSE:For 30 years, we have consecutively performed rectal mucosal punch biopsy to diagnose Hirschsprung's disease. The aim of this study was to evaluate the safety of our technique. METHODS:Patients with suspected Hirschsprung's disease who underwent punch biopsy, including our original "K-PUNCH" method using an S-...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-4010-2
更新日期：2017-02-01 00:00:00
abstract：:Laparoscopy enables surgeons to approach the surgical conditions from a new perspective. Laparoscopic surgery has revolutionized the treatment of choledochal cysts (CDC). Yet, this new technique requires objective evaluations. We have examined the controversies about the CDC dissection, distal common bile duct ligatio...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-013-3266-z
更新日期：2013-04-01 00:00:00
abstract：PURPOSE:Ultraviolet (UV) radiation adversely affects skin health at cellular and molecular levels. Hence, UV radiation can directly induce inflammatory responses in the dermis by inducing erythema, edema, inflammation, dermal fibroblasts alterations, and extracellular matrix modifications. METHODS:Human keratinocytes,...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4384-4
更新日期：2019-01-01 00:00:00
abstract：AIM:The aim of this study was to examine the relationship between birth weight, pulmonary artery (PA) size, and outcome in congenital diaphragmatic hernia (CDH) to establish if PA size has prognostic value. METHODS:The subjects for this study were 39 consecutive left-sided CDH patients treated at our institution accor...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-011-2899-z
更新日期：2011-08-01 00:00:00
abstract：:Juvenile papillomatosis (JP) is a rare benign, proliferative breast tumor in children. We observed a 9-year-old girl with a large soft-tissue mass at the lower outer quadrant of the left breast. Ultrasonography showed an ill-defined, inhomogeneous mass with numerous small, hypoechoic areas. The tumor was completely ex...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000462
更新日期：2001-03-01 00:00:00
abstract：AIM:An experimental study was performed to investigate the efficacy of colchicine in the prevention of fibrosis in the alkaline burn of the esophagus in rats. METHOD:A standard esophageal alkaline burn was produced by the application of 37.5% NaOH for a period of 90 s to the distal esophagus followed by a water rinse....
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1644-5
更新日期：2006-04-01 00:00:00
abstract：UNLABELLED:Anorectal malformation (ARM) is a group of significant birth defects with geographic variation in incidence, individual phenotypes and regional geographic subtypes occurring in approximately 1:5,000 live births. Anorectal atresia with gross terminal colonic distension in the presence of an absent anal canal ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00383-013-3346-0
更新日期：2013-12-01 00:00:00
