Abstract：
PURPOSE:For International Neuroblastoma Staging System (INSS) stages III or IV neuroblastoma (intermediate or high risk), complete excision of the primary tumor is not always feasible. Most current studies on the treatment outcome of these patients have reported on the complete excision status. The aim of this study is to review the treatment outcome after the incomplete resection. METHODS:The medical records of 37 patients that underwent incomplete resection between January 1986 and December 2005 were reviewed retrospectively. Incomplete resection was assessed by review of the operative notes and postoperative computerized tomography. Age, gender, tumor location, INSS stage, N-myc gene copy number, pre- and postoperative therapy, and treatment outcome were reviewed. The treatment outcome was evaluated according to the postoperative treatment protocol in the high-risk group. RESULTS:Intermediate-risk patients were treated with conventional chemotherapy, isotretinoin (ITT) and interleukin-2 (IL-2). High-risk patients were treated with peripheral blood stem cell transplantation (PBSCT), ITT, and IL-2 (N = 11). Before the introduction of PBSCT, the high-risk patients were also treated with the conventional chemotherapy (N = 19). Intermediate-risk patients (N = 5) currently have no evidence of disease (NED). For the high-risk patients (N = 32), 19 patients were treated with chemotherapy alone; 15 patients died of their disease while four patients currently have an NED status. Eight of 11 patients that underwent PBSCT are currently alive. CONCLUSIONS:For intermediate risk, conventional chemotherapy appears to be acceptable treatment. However, for high-risk patients, every effort should be made to control residual disease including the use of myeloablative chemotherapy, differentiating agents and immune-modulating agents.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Moon SB,Park KW,Jung SE,Youn WJdoi
10.1007/s00383-009-2417-8subject
Has Abstractpub_date
2009-09-01 00:00:00pages
789-93issue
9eissn
0179-0358issn
1437-9813journal_volume
25pub_type
杂志文章abstract：:In children with severe chronic constipation, abnormal distribution of substance P (SP) and vasoactive intestinal peptide (VIP), which represent excitatory and inhibitory nerves, respectively, has been reported. The normal distribution of these neuropeptides, however, is not well known. The aim of this study was to de...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050438
更新日期：1998-11-01 00:00:00
abstract：:Intussusception is the commonest surgical complication of Henoch-Sch onlein purpura (HSP), occurring in 1.3%-13.6% of affected children. Colo-colic intussusception is a rare occurrence in HSP, with only three other reported cases. Intussusception in HSP almost always originates in the ileum (90%) or jejunum (7%), and ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s003830050478
更新日期：1998-12-01 00:00:00
abstract：:A rare case of congenital duodenal atresia (DA) associated with a choledochal cyst (CC) is reported. At 38 weeks of gestation, a 1,610-g girl was born by cesarean section with a prenatal diagnosis of DA. After the disorder was confirmed by X-ray, she underwent a duodenoduodenostomy for a complete separation of the duo...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830100703
更新日期：2002-05-01 00:00:00
abstract：AIM:In chick embryos, administration of cadmium (Cd) induces ventral body wall defects (VBWD) similar to human omphalocele. It has been shown that failure of proper VBW formation may be due to disruption of somite development during early embryogenesis. In the VBWD chick model, Cd causes abnormal cell death in the somi...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-012-3202-7
更新日期：2013-01-01 00:00:00
abstract：PURPOSE:Although the principles of the Ladd's procedure for intestinal malrotation in children have remained unchanged since its first description, in the era of minimally invasive surgery it is controversial whether laparoscopy is advantageous over open surgery. The aim of our study was to determine whether the surgic...
journal_title：Pediatric surgery international
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00383-016-3974-2
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:To compare the effect of home intravenous (IV) versus oral antibiotic therapy on complication rates and resource utilization following appendectomy for perforated appendicitis. METHODS:This was a randomized controlled trial of patients aged 4-17 with surgically treated perforated appendicitis from January 2011...
journal_title：Pediatric surgery international
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00383-018-4343-0
更新日期：2018-12-01 00:00:00
abstract：:An infant born in the 34th week of gestation weighing 5,355 g with a massive sacrococcygeal (SC) tumor was delivered by elective cesarean section. An ultrasonographic examination showed solid and cystic components in the tumor. Resection was successfully undertaken with insertion of a Nélaton catheter into the rectum ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000451
更新日期：2001-03-01 00:00:00
abstract：:Primary omental torsion (POT), is a rare cause of acute abdomen commonly affecting obese male adults, whereas it is extremely rare in children. In this retrospective study, we present our experience regarding the management of five children with POT and discuss the diagnostic and therapeutic implications of this entit...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1961-3
更新日期：2007-09-01 00:00:00
abstract：:Measurement of testicular volume is a more readily available method of estimating spermatogenesis in adolescence. Traditionally, testicular volumes have been measured with different type of orchidometers or calipers. The most widely used orchidometer is the Prader orchidometer introduced in 1966. This type of orchidom...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1470-1
更新日期：2005-07-01 00:00:00
abstract：PURPOSE:Controversy exists as regards the best non-invasive diagnostic tool for pediatric cervical lymphadenopathy. The current work aimed to evaluate the reliability, sensitivity, specificity, and accuracy of sonoelastography in diagnosing benign and/or malignant pediatric cervical lymphadenopathy. METHODS:Prospectiv...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4301-x
更新日期：2018-08-01 00:00:00
abstract：:Thyroglossal duct cyst (TGDC) disease, one of the most common developmental neck lesion in the pediatric population, often presents as infected neck mass. The authors reviewed their experience in the management of inflamed TGDC cases, in order to suggest the most efficient approach of these patients regarding the idea...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1562-y
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:Pediatric patients with medically refractory ulcerative colitis (UC) often undergo an initial subtotal colectomy end ileostomy (STC-I). The role of fecal diversion in the subsequent completion proctectomy/ileal-pouch anal anastomosis (CP-IPAA) remains controversial. METHODS:A multi-institutional retrospecti...
journal_title：Pediatric surgery international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00383-019-04440-1
更新日期：2019-04-01 00:00:00
abstract：:The aim of this study was to determine the effects of a synthetic serine protease inhibitor, gabexate mesilate (GM), in rats with ischemia-reperfusion (I-R) damage due to unilateral testicular torsion. Thirty male Sprague-Dawley rats were separated into three groups, each containing ten rats. A sham operation was perf...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1667-y
更新日期：2006-05-01 00:00:00
abstract：BACKGROUND:Preoperative factors have been correlated with pre-incision hypotension (PIH) in children undergoing surgery, suggesting that PIH can be predicted through preoperative screening. We studied blood pressure (BP) changes in the 12 min following the induction of anesthesia to study the incidence of post-inductio...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4359-5
更新日期：2018-12-01 00:00:00
abstract：:Between 1974 and 1988, 86 newborns with perforated necrotizing enterocolitis (NEC) were treated by either laparotomy (usually involving a bowel resection and a temporary stoma) or a peritoneal drain under local anesthesia. The survival of babies in the laparotomy group was 57% versus 59% in the drained group. However,...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：:The presacral cystic teratoma in an infant is reported. The cyst consisted solely of central nervous system tissue. This pathologic finding is extremely rare. A review of the literature reveals no previous report of a teratoma arising in this manner. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0831-2
更新日期：2002-12-01 00:00:00
abstract：:Minor degrees of exomphalos have been known to be associated with vitellointestinal duct anomalies. The most frequent association is Meckel's diverticulum. It is unusual for a fistula to be communicating directly with the exomphalos sac. We report five neonates that presented with a fistula on the exomphalos sac over ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-006-1699-3
更新日期：2006-07-01 00:00:00
abstract：:Peri-catheter calcification is an unusual and previously unreported complication of central venous (CV) catheterization in infants. A 1. 9 Fr Silastic CV catheter was placed in a term infant for administration of total parenteral nutrition and antibiotics following intra-abdominal sepsis. The catheter was removed, wit...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050418
更新日期：1998-10-01 00:00:00
abstract：PURPOSE:Pediatric genitalia injury represents 0.6% of all pediatric trauma. It is crucial for providers to understand whether pediatric patients are at risk for violent mechanisms, such as rape, assault, or other abuse. Therefore, we sought to perform a large database analysis of pediatric and adolescent female genital...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-020-04736-7
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:Radiologically inserted gastrojejunal tubes (RGJ) and surgical jejunostomy (SJ) are established modes of jejunal feeding. The aim of the study is to review nutritional outcomes, complications and the practical consideration to enable patients and carers to make informed choice. METHODS:Retrospective review of ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4303-8
更新日期：2018-09-01 00:00:00
abstract：:An isolated bowel segment (IBS) is a viable loop of bowel that is completely free of its mesenteric attachments. In this study, omentoenteropexy (OEP) was performed in 5-cm-long IBS of rats in order to provide neovascularization. Thirty-two rats were divided into four groups. After OEP, mesenteric division of the IBSs...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01076940
更新日期：1997-07-01 00:00:00
abstract：PURPOSE:To perform a medical evaluation of penile necrosis causes and treatment approaches by examining patients who had penile necrosis after circumcision surgery. METHODS:A total of 24 patients with penile necrosis after circumcision surgery, who presented at various hospitals in Turkey between September 2003 and Ap...
journal_title：Pediatric surgery international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00383-020-04630-2
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Sacrococcygeal teratoma (SCT) is a rare childhood malignancy. Although overall survival is favorable, recurrent tumors are associated with poor outcomes. As most recurrences occur within 3 years of presentation, the utility of long-term surveillance is uncertain. METHODS:Patients with SCTs evaluated and man...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-017-4132-1
更新日期：2017-11-01 00:00:00
abstract：:Esophageal hiatal hernias (EHH) are probably caused by congenital, traumatic, or iatrogenic factors, although the etiology remains unknown. EHHs may develop after abdominal wall closure for omphalocele or gastroschisis due to the increased intra-abdominal pressure, however, there have been few reports in the literatur...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050352
更新日期：1998-07-01 00:00:00
abstract：PURPOSE:Enhanced recovery after surgery (ERAS) pathways are standard practice in adult specialties resulting in improved outcomes. It is unclear whether ERAS principles are applicable to Paediatric Surgery. We performed a scoping review to identify the extent to which ERAS has been used in Paediatric Surgery, the natur...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-016-3986-y
更新日期：2017-01-01 00:00:00
abstract：:Adrenocortical tumors (ACT) are rare in childhood. Determination of malignant potential is difficult. To assess the presentation, clinical behaviour, and histology of these tumors in our center, the records of nine patients with ACTs between 1989 and 2000 were analyzed. The age, sex, clinical presentation, investigati...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0727-1
更新日期：2003-08-01 00:00:00
abstract：:Atypical mycobacterial disease is common in children in Australia. Over 22 years, records were kept prospectively by the senior author. The diagnosis was confirmed in 118 patients, either by culture or by the combination of a positive skin test plus typical histology. There were 46 boys and 72 girls with a median age ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0840-1
更新日期：2002-12-01 00:00:00
abstract：:The most popular techniques for repairing large diaphragmatic defects involve the use of synthetic patches. We present an alternative approach using living tissue. We reviewed our cases of congenital diaphragmatic hernia (CDH) diagnosed within the first 24 h of life from 1991 to 2003. Toldt's fascia (TF) flap was used...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1267-7
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:The aim of this study is to identify the risk factors for esophageal anastomotic stricture (EAS) and/or anastomotic leakage (EAL) after primary repair of esophageal atresia with tracheoesophageal fistula (EA/TEF) in infants. METHODS:A retrospective chart review of 52 patients with congenital EA/TEF between Jan...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-016-3931-0
更新日期：2016-09-01 00:00:00
abstract：:Anterior sagittal anorectoplasty (ASARP) was used for the definitive correction in 107 cases of anovestibular fistula (AVF) between 1996 and 2005. These cases were subjected to three different types of treatment regimes during the same period. Majority of the cases (78) were operated in one stage where postoperatively...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-2019-2
更新日期：2007-12-01 00:00:00
