TGF-β affects enterocyte turnover in correlation with TGF-β receptor expression after massive small bowel resection.

abstract：:A 7-year-old girl with hypereosinophilic syndrome is described, the first such patient to present with inflammatory bowel disease. Hepatosplenomegaly, anaemia, and hypergammaglobulinaemia were also prominent features. Colonoscopy revealed a frank colitis of nonspecific histologic appearance. An elemental diet was unhe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Falade AG,Darbyshire PJ,Raafat F,Booth IW

更新日期：1991-02-01 00:00:00

abstract：OBJECTIVES:Glucagon-like peptide 2 (GLP-2) is a 33 amino acid peptide hormone released from enteroendocrine L-cells following nutrient ingestion. It has been shown to exert trophic effects on the gut. We set out to measure GLP-2 concentrations in blood in children with diarrhoea and malnutrition. METHODS:GLP-2 levels ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Besa EC,Chandwe K,Banda R,Munalula L,Kalomo L,Amadi B,Kelly P

更新日期：2020-04-01 00:00:00

abstract：:Monitoring therapy in esophageal inflammatory disorders such as eosinophilic esophagitis and reflux esophagitis often requires frequent endoscopic evaluation. We recently reported the effective use of unsedated in-office transnasal esophagoscopy that significantly decreased costs and anesthetic exposure associated wit...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hall CHT,Nguyen N,Furuta GT,Prager J,Deboer E,Deterding R,Menard-Katcher C,Capocelli KE,Kramer RE,Friedlander JA

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:Oxidative stress has been implicated in the development of nonalcoholic fatty liver disease (NAFLD) and progression to the more severe form, nonalcoholic steatohepatitis (NASH), in children. We aimed to study the clinical correlation between bilirubin, a potent endogenous antioxidant with cytoprotective prop...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Puri K,Nobili V,Melville K,Corte CD,Sartorelli MR,Lopez R,Feldstein AE,Alkhouri N

更新日期：2013-07-01 00:00:00

abstract：:Acetylcholinesterase (AChE) activity was measured in rectal suction biopsies from 392 patients investigated for Hirschsprung's disease (HD). Results in HD (2.7-23.7 RU; n = 37) were not clearly differentiated from those in patients without HD (0.6-18.0 RU; n = 355). Sample instability was shown not to be a significant...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Wells FE,Addison GM

更新日期：1986-11-01 00:00:00

abstract：:We evaluated fecal clearance of alpha 1-antitrypsin (alpha 1-AT) as a method of detecting and quantitating intestinal protein loss in patients with inflammatory bowel disease. We investigated alpha 1-AT clearance (C alpha 1-AT) in 14 patients (seven with Crohn's disease, seven with ulcerative colitis) and in 10 childr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Grill BB,Hillemeier AC,Gryboski JD

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Despite studies indicating that vitamin D intake among Swedish children does not meet the recommendation, little is known of their vitamin D status. The aim of the present study was to examine vitamin D status in preschool-age children in relation to vitamin D intake, season, body mass index, a...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Öhlund I,Silfverdal SA,Hernell O,Lind T

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Hepatic lesions have been described in Alagille syndrome (ALGS) in isolated case reports, and most of these have been reported to be hepatocellular carcinoma. OBJECTIVES:The aim of the present study was to determine the frequency, imaging, and histopathologic characteristics of hepatic lesions in children w...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Alhammad A,Kamath BM,Chami R,Ng VL,Chavhan GB

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:In the present study, we studied a cohort of patients with very early onset inflammatory bowel disease (IBD) to determine the frequency of mutations in the interleukin 10 (IL10) receptor genes as a cause of early-onset IBD. METHODS:Sanger sequencing was performed to determine the presence of IL10 and/or IL1...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Beser OF,Conde CD,Serwas NK,Cokugras FC,Kutlu T,Boztug K,Erkan T

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:In 2011, the United States Surgeon General issued a call to action to "identify and address obstacles to greater availability of safe banked donor milk for fragile infants." The purpose of the present study is to analyze patterns in donor human milk (DHM) and fortifier use in level 2, 3, and 4 neonatal facili...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Perrin MT

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate the multidimensional gastrointestinal symptoms predictors of generic health-related quality of life (HRQOL) in pediatric patients with inflammatory bowel disease from the perspectives of pediatric patients and parents. METHODS:The Pediatric Quality of Life Inventory G...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Varni JW,Shulman RJ,Self MM,Saeed SA,Patel AS,Nurko S,Neigut DA,Saps M,Franciosi JP,Denham JM,Zacur GM,Dark CV,Bendo CB,Pohl JF,Pediatric Quality of Life Inventory Gastrointestinal Symptoms Module Testing Study Consortium.

更新日期：2016-12-01 00:00:00

abstract：:Hepatic ornithine carbamoyltransferase (OCT) and alcohol dehydrogenase (ADH) activities were measured in six groups of rats: (A) fed a severe zinc-(Zn-) deficient diet (1.98 ppm) for 5 weeks; (B) pair-fed control for group (A); (C) fed a less severe Zn-deficient diet (6.10 ppm) for 5 weeks; (D) pair-fed control for gr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Indo Y,Nagata N,Higashi A,Matsuda I,Kashiwabara N,Nakashima I

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Familial defective apolipoprotein B-100, a dominantly inherited form of hypercholesterolemia caused by a single Arg3500Gln mutation, is silent in childhood but may confer a high risk of cardiovascular disease in adulthood. The objective was to determine the prevalence of familial defective apolipoprotein B-1...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Viola S,Benlian P,Morali A,Dobbelaere D,Lacaille F,Rieu D,Ginies JL,Maurage C,Meyer M,Lachaux A,Larchet M,Lenearts C,Goulet O,Sarles J,Mouterde O,Girardet JP,French-Speaking Group for Pediatric Hepatogastroenterology and

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Feeding problems are common in infants and young children. A multidisciplinary team approach contributes to better patient care. However, few quantitative data on multidisciplinary feeding assessment of children have been published. OBJECTIVES The first aim of this study was to characterize the etiology of f...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Rommel N,De Meyer AM,Feenstra L,Veereman-Wauters G

更新日期：2003-07-01 00:00:00

abstract：:Breath methane excretion is uncommon in children compared with adults. Certain intracolonic conditions, however, have been associated with enhanced methane generation. We hypothesized that encopretic and constipated children, who have abnormal colonic transit times, more likely would excrete methane than healthy child...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fiedorek SC,Pumphrey CL,Casteel HB

更新日期：1990-05-01 00:00:00

abstract：:Histologic assessment as well as information about the disaccharidase activity of the small intestinal mucosa can be useful in the management of patients with small intestinal mucosal damage. In an effort to determine whether the degree of small intestinal mucosal damage would be reflected in a corresponding reduction...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Shulman RJ,Langston C,Lifschitz CH

更新日期：1991-01-01 00:00:00

abstract：:An enzyme-linked immunosorbent assay technique was developed to determine serum antigliadin antibodies of the IgA, IgE, IgG, and IgM classes. The antibody level of each serum specimen was expressed as an index value, i.e., optical density of test serum/optical density of cutoff, where cutoff was calculated for each im...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Juto P,Fredrikzon B,Hernell O

更新日期：1985-10-01 00:00:00

abstract：:Enteric neuropathies comprise a vast and disparate array of congenital and acquired disorders of the enteric nervous system (ENS), reflecting both the complexity of its neuronal composition and the many interactions that modulate its function. Although present therapeutic strategies, largely limited to surgery and the...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Thapar N

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:The main objective of this work was to study plasma oxytocin concentration of children with psychosomatic recurrent abdominal pain and children with organic abdominal disease producing pain. Another objective was to study plasma oxytocin in children with psychosomatic recurrent pain over time and its relation...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Alfvén G

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:The probiotic Lactobacillus GG is effective in promoting a more rapid recovery of acute, watery diarrhea in children with rotavirus enteritis. Very limited information is available, however, on the potential role of such agents in non-rotaviral diarrheal episodes. Furthermore, no evidence is available concer...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Guandalini S,Pensabene L,Zikri MA,Dias JA,Casali LG,Hoekstra H,Kolacek S,Massar K,Micetic-Turk D,Papadopoulou A,de Sousa JS,Sandhu B,Szajewska H,Weizman Z

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Rotavirus A (RVA) is one of the leading causes of acute gastroenteritis worldwide; however, few studies assessed RVA genetics with community surveillance. OBJECTIVES:This study aimed to investigate clinical data, genetic diversity, and coinfection patterns of RVA infections in children from 2 to 36 months o...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Pankov RC,Gondim RNDG,Prata MMG,Medeiros PHQS,Veras HN,Santos AKS,Havt A,da Silva MFM,Fumian TM,Miagostovich MP,Leite JPG,Lima AAM

更新日期：2019-10-01 00:00:00

abstract：:Anti-tumor necrosis factor-alpha (TNF-α) blockade is so far the most effective therapy for extensive pediatric Crohn disease (CD), but loss of response is frequently encountered. We describe here the use of golimumab (Simponi) in 6 pediatric CD patients with antibody formation/loss of response to infliximab and adalim...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Merras-Salmio L,Kolho KL

更新日期：2016-09-01 00:00:00

abstract：:Few advances would contribute more to the growth and well-being of infants and children in the developing world than the making available of acceptable staple foods that are easy to grow and process, nutritionally complete enough to serve as the major weaning food, and safe without refrigeration. High-fat quality-prot...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Graham GG

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVES:The transfer of exogenous genetic material to cells within the gastrointestinal (GI) tract has many potential therapeutic applications. An attractive feature of the GI tract for gene transfer is its accessibility through the orogastric route. In this study, we evaluated the stability of recombinant adeno-ass...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Shao G,Greathouse K,Huang Q,Wang CM,Sferra TJ

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVES:There are few data on pediatric celiac disease in the United States. The aim of our study was to describe the presentation of celiac disease among children with a normal and an elevated body mass index (BMI) for age, and to study their BMI changes following a gluten-free diet (GFD). PATIENTS AND METHODS:One...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Reilly NR,Aguilar K,Hassid BG,Cheng J,Defelice AR,Kazlow P,Bhagat G,Green PH

更新日期：2011-11-01 00:00:00

abstract：:Twenty children with active ulcerative colitis were assessed before and after 8 weeks of medical therapy with 5-aminosalicylic acid (5-ASA) derivatives and corticosteroids. Local therapy was given for distal disease (seven cases); other disease was treated with oral prednisolone (1-2 mg/kg/day, maximum 40 mg). Eightee...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Beattie RM,Nicholls SW,Domizio P,Williams CB,Walker-Smith JA

更新日期：1996-05-01 00:00:00

abstract：:When conventional treatment with upright positioning and thickened feedings fails to control vomiting associated with gastroesophageal reflux (GER) of infancy, malnutrition and growth failure may result. If this occurs, fundoplication is usually recommended. In this study, 12 infants with growth failure associated wit...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ferry GD,Selby M,Pietro TJ

更新日期：1983-01-01 00:00:00

abstract：:The prolonged intestinal retention of a Watson biopsy capsule in a 12-year-old girl with chronic diarrhea is reported. Radiological investigation showed a duodenal obstruction due to superior mesenteric artery syndrome. A preliminary barium study of the upper gastrointestinal tract, before performing blind intestinal ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bonamico M,Roggini M,Pierro A,Dionisi Vici C,Bitti IM

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Earlier studies report the excessive faecal excretions of bile acids and dietary residues in cystic fibrosis (CF). However, few of these investigated large groups of patients using modern pancreatin preparations and little data exists reporting carbohydrate excretion. We therefore aimed to characterise the g...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Walters MP,Littlewood JM

更新日期：1998-09-01 00:00:00

abstract：:Most children with chronic hepatitis C are infected vertically, have a low natural seroconversion rate, and carry a lifetime risk of cirrhosis and cancer. Affected children are usually asymptomatic, and histological findings are mild with a low risk of progression, although 5% develop significant liver disease in chil...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Wirth S,Kelly D,Sokal E,Socha P,Mieli-Vergani G,Dhawan A,Lacaille F,Saint Raymond A,Olivier S,Taminiau J

更新日期：2011-02-01 00:00:00