Inflammation and the peritoneal membrane: causes and impact on structure and function during peritoneal dialysis.

abstract：BACKGROUND AND AIM:Immunization with live virus vaccines may cause an immunosuppression with lymphopaenia, impaired cytokine production and defective lymphocyte response to mitogenes. These abnormalities were described in subjects vaccinated against measles. This study was performed to analyse the host immune response ...

journal_title：Mediators of inflammation

authors： Pukhalsky AL,Shmarina GV,Bliacher MS,Fedorova IM,Toptygina AP,Fisenko JJ,Alioshkin VA

更新日期：2003-08-01 00:00:00

abstract：:Chronic pain has to be considered in all respects a debilitating disease and 10-20% of the world's adult population is affected by this disease. In the most general terms, pain is symptomatic of some form of dysfunction and (often) the resulting inflammatory processes in the body. In the study of pain, great attention...

journal_title：Mediators of inflammation

authors： Vodo S,Bechi N,Petroni A,Muscoli C,Aloisi AM

更新日期：2013-01-01 00:00:00

abstract：:The effects of anti-inflammatory plant extracts, such as black tea extract (BTE) and resveratrol (RSV) could modulate cell activation leading to atherosclerosis, however there is little comparative information about how different endothelial cell types are affected by these compounds. In order to compare human endothe...

journal_title：Mediators of inflammation

authors： Lakota K,Mrak-Poljsak K,Rozman B,Sodin-Semrl S

更新日期：2009-01-01 00:00:00

abstract：:Macrophage migration inhibitory factor (MIF) has recently been forwarded as a critical regulator of inflammatory conditions, and it has been hypothesized that MIF may have a role in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD). Hence, we examined effects of MIF immunoneutralization on th...

journal_title：Mediators of inflammation

authors： Korsgren M,Källström L,Uller L,Bjerke T,Sundler F,Persson CG,Korsgren O

更新日期：2000-01-01 00:00:00

abstract：:The regulatory functions of glycosaminoglycan hyaluronan (HA) are suggested to be dependent on its molecular weight (MW). Proinflammatory and stimulatory effects are proposed mainly for the low MW HA. However, the complex response of blood phagocytes to HA of different MW is unclear. Herein, the effects of highly puri...

journal_title：Mediators of inflammation

authors： Safrankova B,Gajdova S,Kubala L

更新日期：2010-01-01 00:00:00

abstract：:Bortezomib is a proteasome inhibitor used for hematologic cancer treatment. Since it can suppress NF-κB activation, which is critical for the inflammatory process, bortezomib has been found to possess anti-inflammatory activity. In this study, we evaluated the effect of bortezomib on experimental autoimmune uveitis (E...

journal_title：Mediators of inflammation

authors： Hsu SM,Yang CH,Shen FH,Chen SH,Lin CJ,Shieh CC

更新日期：2015-01-01 00:00:00

abstract：:Epidermal growth factor (EGF) is a 53-amino acid peptide that plays an important role in regulating cell growth, survival, migration, apoptosis, proliferation, and differentiation. In addition, EGF has been established to be an effective intestinal regulator helping to protect intestinal barrier integrity, which was e...

journal_title：Mediators of inflammation

authors： Tang X,Liu H,Yang S,Li Z,Zhong J,Fang R

更新日期：2016-01-01 00:00:00

abstract：:Metabolic hormones have been associated with reproductive function modulation. Thus, the aim of this study was: (i) to characterize the immunolocalization, mRNA and protein levels of leptin (LEP), Ghrelin (GHR) and respective receptors LEPR and Ghr-R1A, throughout luteal phase; and (ii) to evaluate the role of LEP and...

journal_title：Mediators of inflammation

authors： Galvão A,Tramontano A,Rebordão MR,Amaral A,Bravo PP,Szóstek A,Skarzynski D,Mollo A,Ferreira-Dias G

更新日期：2014-01-01 00:00:00

abstract：:Behçet's disease (BD) is a multisystemic disorder of unknown etiology characterized by the "triple symptom complex" consisting of recurrent oral aphthosis, genital ulcers, and chronic relapsing bilateral uveitis. Recurrent mucocutaneous lesions are generally considered the hallmark of the disease, being the most commo...

journal_title：Mediators of inflammation

authors： Rotondo C,Lopalco G,Iannone F,Vitale A,Talarico R,Galeazzi M,Lapadula G,Cantarini L

更新日期：2015-01-01 00:00:00

abstract：:With the development of culture-independent techniques, numerous studies have demonstrated that the lower airway is not sterile in health and harbors diverse microbial communities. Furthermore, new evidence suggests that there is a distinct lower airway microbiome in those with chronic respiratory disease. To understa...

journal_title：Mediators of inflammation

authors： Lu J,Xiong L,Zhang X,Liu Z,Wang S,Zhang C,Zheng J,Wang G,Zheng R,Simpson JL,Wang F

更新日期：2017-01-01 00:00:00

abstract：:Nephrolithiasis is characterized by calcification of stones in the kidneys from an unknown cause. Animal models demonstrated the functional roles of the transient receptor potential vanilloid member 5 (TRPV5) gene in calcium renal reabsorption and hypercalciuria. Therefore, TRPV5 was suggested to be involved in calciu...

journal_title：Mediators of inflammation

authors： Khaleel A,Wu MS,Wong HS,Hsu YW,Chou YH,Chen HY

更新日期：2015-01-01 00:00:00

abstract：:Little is known about the cause and pathophysiology of middermal elastolysis (MDE). In this condition, variable inflammatory infiltrate may be present or not together with loss of elastic fibres in the middermis that spares both papillary and lower reticular dermis. MDE may be a consequence of abnormal extracellular m...

journal_title：Mediators of inflammation

authors： De Cunto G,Lamberti A,de Santi MM,Miracco C,Fimiani M,Lungarella G,Cavarra E

更新日期：2017-01-01 00:00:00

abstract：UNLABELLED:The aim of this study was to investigate the relationship between urinary eosinophil protein X (uEPX) and asthma symptoms, lung function, and other markers of eosinophilic airway inflammation in asthmatic school children. METHODS:A cross-sectional study was performed in 180 steroid dependent atopic children...

journal_title：Mediators of inflammation

authors： Nuijsink M,Hop WC,Sterk PJ,Duiverman EJ,Hiemstra PS,de Jongste JC,CATO Study Group.

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The cyclooxygenase- (COX-) 2/microsomal PGE-synthase- (mPGES-) 1/PGE-receptor- (EP-) 4 axis could play a key role in the physiopathology of abdominal aortic aneurysm (AAA) in humans. In this study, we investigated the influence of cardiovascular risk factors on the expression of the PGE2 pathway in human AAA...

journal_title：Mediators of inflammation

authors： Dilmé JF,Solà-Villà D,Bellmunt S,Romero JM,Escudero JR,Camacho M,Vila L

更新日期：2014-01-01 00:00:00

abstract：:Osteoarthritis (OA) belongs to a group of degenerative diseases. Synovial inflammation, cartilage abrasion, and subchondral sclerosis are characteristics of OA. Researchers do not fully understand the exact etiology of OA. However, matrix metalloproteinases (MMPs), which are responsible for cartilage matrix degradatio...

journal_title：Mediators of inflammation

authors： Chen YT,Hou CH,Hou SM,Liu JF

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Nonbacterial prostatitis has no established etiology. We hypothesized that proteinase-activated receptor-1 (PAR1) can play a role in prostatitis. We therefore investigated the effects of PAR1 stimulation in the context of a new model of murine nonbacterial prostatitis. METHODS:Using a hapten (ethanol-dinitr...

journal_title：Mediators of inflammation

authors： Stanton MM,Nelson LK,Benediktsson H,Hollenberg MD,Buret AG,Ceri H

更新日期：2013-01-01 00:00:00

abstract：:The observed effects after ozone exposure strongly depend on ozone concentration and exposure time. We hypothesized that depending on the O3 exposure protocol, mainly either an oxidant damage or an inflammation will determine the O3 toxicity. We compared two different ozone exposure protocols: an acute exposure (3 ppm...

journal_title：Mediators of inflammation

authors： van Hoof HJ,Zijlstra FJ,Voss HP,Garrelds IM,Dormans JA,van Bree L,Bast A

更新日期：1997-01-01 00:00:00

abstract：:The CCN family member 2 (CCN2, also known as connective tissue growth factor) may behave as a risk biomarker and a potential therapeutic target for renal disease. CCN2 participates in the regulation of inflammation and fibrosis. TGF-β is considered the main fibrogenic cytokine; however, in some pathological settings T...

journal_title：Mediators of inflammation

authors： Rodrigues-Díez R,Rayego-Mateos S,Orejudo M,Aroeira LS,Selgas R,Ortiz A,Egido J,Ruiz-Ortega M

更新日期：2015-01-01 00:00:00

abstract：:Inflammation is considered to be one of the most critical factors involved in the development of complex metabolic diseases such as type 2 diabetes, cancer, and cardiovascular disease. A few decades ago, the discovery of mitochondria-associated endoplasmic reticulum (ER) membrane (MAM) was followed by the identificati...

journal_title：Mediators of inflammation

authors： Thoudam T,Jeon JH,Ha CM,Lee IK

更新日期：2016-01-01 00:00:00

abstract：AIM:This study was undertaken in order to determine whether anti-inflammatory cytokine interleukin-10 is responsible for a previously described protection against Klebsiella infection mediated by antilipopolysaccharide antibodies. METHODS:BALB/c mice were infected intraperitoneally with a lethal challenge of Klebsiell...

journal_title：Mediators of inflammation

authors： Rukavina T,Ticac B,Vasiljev V

更新日期：2006-01-01 00:00:00

abstract：:Microscopic colitis (MC), comprising collagenous colitis (CC) and lymphocytic colitis (LC), is a common cause of chronic diarrhea. Various immune cell infiltrations in the epithelium and lamina propria are seen in MC immunopathology. We compared gene and protein expressions of different immune cell attracting chemokin...

journal_title：Mediators of inflammation

authors： Günaltay S,Kumawat AK,Nyhlin N,Bohr J,Tysk C,Hultgren O,Hultgren Hörnquist E

更新日期：2015-01-01 00:00:00

abstract：:This study was carried out to investigate whether ADM can modulate LPS-induced inflammation and apoptosis in rat Leydig cells. Leydig cells were treated with ADM before LPS-induced cytotoxicity. We determined the concentrations of ROS, MDA, GSH, LDH, and testosterone and the MMP. The mRNA levels of IL-1, IL-6, iNOS, a...

journal_title：Mediators of inflammation

authors： Zhou PH,Hu W,Zhang XB,Wang W,Zhang LJ

更新日期：2016-01-01 00:00:00

abstract：:A prominent feature of inflammatory diseases is endothelial dysfunction. Factors associated with endothelial dysfunction include proinflammatory cytokines, adhesion molecules, and matrix degrading enzymes. At the transcriptional level, they are regulated by the histone deacetylase sirtuin (SIRT) 1 via its actions on t...

journal_title：Mediators of inflammation

authors： Lappas M

更新日期：2012-01-01 00:00:00

abstract：:The aim of the present study was to compare serum levels of soluble forms of interleukin-2 receptor, CD4 and CD8, released by lymphocytes during activation of the immune system, in patients with allergic bronchial asthma, with those in healthy subjects. Significantly higher levels of soluble IL-2R and soluble CD4 were...

journal_title：Mediators of inflammation

authors： Lorenzo GD,Mansueto P,Melluso M,Morici G,Norrito F,Cigna D,Candore G,Caruso C

更新日期：1995-01-01 00:00:00

abstract：:Extracellular bacterial ribonucleases such as binase from Bacillus pumilus possess cytotoxic activity against tumor cells with a potential for clinical application. Moreover, they may induce activation of tumor-derived macrophages either into the M1-phenotype with well-documented functions in the regulation of the ant...

journal_title：Mediators of inflammation

authors： Makeeva A,Rodriguez-Montesinos J,Zelenikhin P,Nesmelov A,Preissner KT,Cabrera-Fuentes HA,Ilinskaya ON

更新日期：2017-01-01 00:00:00

abstract：:TLRs recognize a broad spectrum of microorganism molecules, triggering a variety of cellular responses. Among them, phagocytosis is a critical process for host defense. Leukotrienes (LTs), lipid mediators produced from 5-lipoxygenase (5-LO) enzyme, increase FcγR-mediated phagocytosis. Here, we evaluated the participat...

journal_title：Mediators of inflammation

authors： Pinheiro CDS,Monteiro APT,Dutra FF,Bozza MT,Peters-Golden M,Benjamim CF,Canetti C

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Platelet-activating factor (PAF) seems to be implicated in systemic lupus erythematosus (SLE) patients with associated renal diseases. AIMS:In this study, we ensured the role of PAF in SLE patients without renal complications. METHODS:Blood PAF and acetylhydrolase activity, plasma soluble phospholipase A(2...

journal_title：Mediators of inflammation

authors： Denizot Y,Liozon E,Guglielmi L,Ly K,Soria P,Loustaud V,Vidal E,Jauberteau MO

更新日期：2003-04-01 00:00:00

abstract：:Although it is now accepted that killer-cell inhibitory receptors (KIRs), which were molecularly cloned in 1995, deliver negative signals to natural killer (NK) cells regarding the recognition of target cells, it is still unclear how the expression of these receptors on lymphocytes is regulated. Therefore, we investig...

journal_title：Mediators of inflammation

authors： Kogure T,Fujinaga H,Niizawa A,Hai LX,Shimada Y,Ochiai H,Terasawa K

更新日期：1999-01-01 00:00:00

abstract：:Thiopurines are extensively used immunosuppressants for the treatment of inflammatory bowel disease (IBD). The polymorphism of thiopurine S-methyltransferase (TPMT) influences thiopurine metabolism and therapy outcome. We used a TPMT knockdown (kd) model of human Jurkat T-lymphocytes cells to study the effects of trea...

journal_title：Mediators of inflammation

authors： Misdaq M,Ziegler S,von Ahsen N,Oellerich M,Asif AR

更新日期：2015-01-01 00:00:00

abstract：:Tryptophan (trp) metabolism is an important regulatory component of gut mucosal homeostasis and the microbiome. Metabolic pathways targeting the trp can lead to a myriad of metabolites, of both host and microbial origins, some of which act as endogenous low-affinity ligands for the aryl hydrocarbon receptor (AhR), a c...

journal_title：Mediators of inflammation

authors： Puccetti M,Paolicelli G,Oikonomou V,De Luca A,Renga G,Borghi M,Pariano M,Stincardini C,Scaringi L,Giovagnoli S,Ricci M,Romani L,Zelante T

更新日期：2018-02-18 00:00:00