Testosterone-induced effects on lipids and inflammation.

Abstract:

:Chronic pain has to be considered in all respects a debilitating disease and 10-20% of the world's adult population is affected by this disease. In the most general terms, pain is symptomatic of some form of dysfunction and (often) the resulting inflammatory processes in the body. In the study of pain, great attention has been paid to the possible involvement of gonadal hormones, especially in recent years. In particular, testosterone, the main androgen, is thought to play a beneficial, protective role in the body. Other important elements to be related to pain, inflammation, and hormones are lipids, heterogenic molecules whose altered metabolism is often accompanied by the release of interleukins, and lipid-derived proinflammatory mediators. Here we report data on interactions often not considered in chronic pain mechanisms.

journal_name

Mediators Inflamm

authors

Vodo S,Bechi N,Petroni A,Muscoli C,Aloisi AM

doi

10.1155/2013/183041

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

183041

eissn

0962-9351

issn

1466-1861

journal_volume

2013

pub_type

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