Social cognition and quality of life in schizophrenia.

abstract：:The serotonin and dopamine neurotransmitter systems are candidate pathways in the development of schizophrenia because of the assumed causal relationship with the observed symptoms as well as effective targeting of the corresponding receptors by antipsychotic drugs. However, genetic association studies have systematic...

journal_title：Schizophrenia research

authors： Domínguez E,Loza MI,Padín F,Gesteira A,Paz E,Páramo M,Brenlla J,Pumar E,Iglesias F,Cibeira A,Castro M,Caruncho H,Carracedo A,Costas J

更新日期：2007-02-01 00:00:00

abstract：:Although the seasonal patterns of admissions of affective disorder have been extensively studied, less attention has been given to the seasonal admission patterns of schizophrenia. The traditional method of aggregating the data over a study period, rather than analysing by year of admission may obscure potentially rel...

journal_title：Schizophrenia research

authors： Clarke M,Moran P,Keogh F,Morris M,Kinsella A,Walsh D,Larkin C,O'Callaghan E

更新日期：1998-11-30 00:00:00

abstract：:Three-channel actometry was used to study neuroleptic-induced akathisia (NIA), a common and often serious disorder in association of traditional neuroleptic therapy. The aim was to explore the diagnostic possibilities of actometry in NIA and to examine in detail the motor phenomenology of the disorder in detail. The a...

journal_title：Schizophrenia research

authors： Tuisku K,Lauerma H,Holi M,Markkula J,Rimon R

更新日期：1999-11-30 00:00:00

abstract：INTRODUCTION:EEG power in the delta, theta and beta1 bands has been shown to be positively correlated with negative symptoms in first episode psychotic patients. The present study investigates this correlation in an "at risk mental state for psychosis" (ARMS) with the aim to improve prediction of transition to psychosi...

journal_title：Schizophrenia research

authors： Zimmermann R,Gschwandtner U,Wilhelm FH,Pflueger MO,Riecher-Rössler A,Fuhr P

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Proton magnetic resonance spectroscopy (1H-MRS) studies of schizophrenia suggest an effect of the disease or of antipsychotic medications on brain N-acetyl aspartate (NAA), a marker of neuronal viability. We studied in the rat the effect of antipsychotic drugs on NAA in several brain regions where NAA reduct...

journal_title：Schizophrenia research

authors： Bustillo J,Wolff C,Myers-y-Gutierrez A,Dettmer TS,Cooper TB,Allan A,Lauriello J,Valenzuela CF

更新日期：2004-01-01 00:00:00

abstract：:Schizophrenia is associated with premature mortality and a high rate of sudden, unexpected deaths. Autopsy data are scant, and in studies using death certificates or root cause assessments, a majority of sudden deaths remained unexplained. In the community, post-mortem data indicate that the most common cause of sudde...

journal_title：Schizophrenia research

authors： Ifteni P,Correll CU,Burtea V,Kane JM,Manu P

更新日期：2014-05-01 00:00:00

abstract：:Research suggests that social stress exposure influences illness presentation and course among youth at clinical high-risk (CHR) for psychosis, though less is known about the extent to which self-reported perceptions of social stress relate to the severity of positive symptoms. Importantly, despite the notion that you...

journal_title：Schizophrenia research

authors： Millman ZB,Pitts SC,Thompson E,Kline ER,Demro C,Weintraub MJ,DeVylder JE,Mittal VA,Reeves GM,Schiffman J

更新日期：2018-02-01 00:00:00

abstract：:The glutamatergic dysfunction hypothesis of schizophrenia implicates the genes involved in glutamatergic transmission as strong candidates for schizophrenia-susceptibility. Recent linkage and association studies have identified the glutamate receptor, ionotropic, delta 1 gene GRID1 on 10q22 as a strong candidate for s...

journal_title：Schizophrenia research

authors： Guo SZ,Huang K,Shi YY,Tang W,Zhou J,Feng GY,Zhu SM,Liu HJ,Chen Y,Sun XD,He L

更新日期：2007-07-01 00:00:00

abstract：:Previous research demonstrates that people with schizophrenia have abnormally 'restricted' visual scanpaths to face and facial expression stimuli, which appear to be diagnostically specific to schizophrenia [Schizophr. Res. 55 (2002) 159; Biol. Psychiatry 52 (2002) 338]. This study examined the familial transmission o...

journal_title：Schizophrenia research

authors： Loughland CM,Williams LM,Harris AW

更新日期：2004-03-01 00:00:00

abstract：:A role for immune processes in the pathogenesis of schizophrenia has been suggested by genetic and epidemiological studies, as well as cross-sectional studies on blood and brain samples. However, results are heterogeneous, which is likely caused by low samples sizes, insufficient control of confounders that influence ...

journal_title：Schizophrenia research

authors： van Mierlo HC,Schot A,Boks MPM,de Witte LD

更新日期：2020-03-01 00:00:00

abstract：:Attention Deficit/Hyperactivity Disorder (ADHD) is the most common psychiatric disorder in childhood. It is unclear whether ADHD increases the risk of non-affective psychotic disorder (NAPD). The study included a matched cohort, drawn from all born in Sweden 1987-1991 (n = 548,852). ADHD was defined as ICD diagnosis a...

journal_title：Schizophrenia research

authors： Björkenstam E,Pierce M,Björkenstam C,Dalman C,Kosidou K

更新日期：2020-04-01 00:00:00

abstract：:Non-compliance problems may rise to 50% among patients undergoing neuroleptic treatment. There are no direct measures available to predict compliance, if previous non-compliance is not taken into account. Attitudes towards neuroleptic treatment and insight into psychotic symptoms may vary during the course of the trea...

journal_title：Schizophrenia research

authors： Kampman O,Lehtinen K,Lassila V,Leinonen E,Poutanen O,Koivisto A

更新日期：2000-10-27 00:00:00

abstract：BACKGROUND:Higher liability to psychosis is associated with low self-esteem and increased sensitivity to social stress. Recently, we reported a positive relation between liability to psychosis and affective and psychotic responses to social stress. This study investigated how self-esteem moderates paranoia, peak subjec...

journal_title：Schizophrenia research

authors： Jongeneel A,Pot-Kolder R,Counotte J,van der Gaag M,Veling W

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The Positive and Negative Syndrome Scale (PANSS) total score is widely used to assess antipsychotic efficacy, however schizophrenia is a multi-dimensional disorder. We conducted a 5-factor analysis for evaluating the efficacy of iloperidone vs. placebo across these different domains in the treatment of schiz...

journal_title：Schizophrenia research

authors： Citrome L,Meng X,Hochfeld M

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Recovery is the ultimate goal of psychosis treatment. Basic self-disturbances (BSDs) are non-psychotic phenomena associated with clinical outcome, present in prodromal, psychotic and residual phases of psychotic disorders. AIM:To investigate the relationship between BSDs and recovery seven years after first...

journal_title：Schizophrenia research

authors： Svendsen IH,Øie MG,Møller P,Nelson B,Haug E,Melle I

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Family studies have suggested that schizophrenia and bipolar disorders share some susceptibility factors. Schizotypal personality disorder (SPD) may be an intermediate phenotype common both to schizophrenia and bipolar disorders. We explored the familiality of schizotypal dimensions by comparing the magnitud...

journal_title：Schizophrenia research

authors： Schürhoff F,Laguerre A,Szöke A,Méary A,Leboyer M

更新日期：2005-12-15 00:00:00

abstract：:Mismatch negativity (MMN) and P3a are auditory event-related potential (ERP) components that show robust deficits in schizophrenia (SZ) patients and exhibit qualities of endophenotypes, including substantial heritability, test-retest reliability, and trait-like stability. These measures also fulfill criteria for use a...

journal_title：Schizophrenia research

authors： Light GA,Swerdlow NR,Thomas ML,Calkins ME,Green MF,Greenwood TA,Gur RE,Gur RC,Lazzeroni LC,Nuechterlein KH,Pela M,Radant AD,Seidman LJ,Sharp RF,Siever LJ,Silverman JM,Sprock J,Stone WS,Sugar CA,Tsuang DW,Tsuang MT

更新日期：2015-04-01 00:00:00

abstract：:The immune hypothesis of schizophrenia has gained significant popularity in recent years in schizophrenia research. Evidence suggests that the peripheral immune system communicates with central nervous system and the effect propagates through microglial and lymphocyte crosstalk, especially during neuro-inflammation. A...

journal_title：Schizophrenia research

authors： Varun CN,Venkataswamy MM,Ravikumar R,Nagaraju R,Debnath M,Varambally S,Venkatasubramanian G,Ravi V

更新日期：2019-10-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNAs that mainly function as negative regulators of gene expression (Lai, 2002) and have been shown to be involved in schizophrenia etiology through genetic and expression studies (Burmistrova et al., 2007; Hansen et al., 2007a; Perkins et al., 2007; Beveridge et al., 2010; Kim ...

journal_title：Schizophrenia research

authors： Kim AH,Parker EK,Williamson V,McMichael GO,Fanous AH,Vladimirov VI

更新日期：2012-10-01 00:00:00

abstract：:The finding of pyramidal cell disarray in the hippocampus of patients with schizophrenia has been disputed by several groups. Conflicting results have been attributed to differences in the subtype of patients used, staining method, the side of the hippocampus studied and the way cellular disarray has been measured. In...

journal_title：Schizophrenia research

authors： Casanova MF,Rothberg B

更新日期：2002-05-01 00:00:00

abstract：:In 1990 a satellite session of the American College of Neuropsychopharmacology (ACNP) Annual Meeting was held that focused on the question of whether progressive changes in brain structure occur in schizophrenia and this session raised considerable controversy. Eighteen years later, on December 12, 2008, after much da...

journal_title：Schizophrenia research

authors： Borgwardt SJ,Dickey C,Hulshoff Pol H,Whitford TJ,DeLisi LE

更新日期：2009-07-01 00:00:00

abstract：:Nondeclarative memory (NDM) has subtypes associated with different brain regions; learning of a probabilistic classification task is impaired by striatal damage and learning of a gambling task is impaired by ventromedial prefrontocortical damage. Typical and atypical antipsychotic medications differentially affect imm...

journal_title：Schizophrenia research

authors： Beninger RJ,Wasserman J,Zanibbi K,Charbonneau D,Mangels J,Beninger BV

更新日期：2003-06-01 00:00:00

abstract：:To clarify the molecular mechanism of phencyclidine (PCP)-induced schizophreniform psychosis in humans and of behavioral abnormalities in experimental animals, we used differential screening of a cDNA library from the cerebral cortex of rats treated with PCP. We identified a PCP-induced cDNA clone as the gene encoding...

journal_title：Schizophrenia research

authors： Shimizu E,Shirasawa H,Kodama K,Kuroyanagi H,Shirasawa T,Sato T,Simizu B

更新日期：1997-06-20 00:00:00

abstract：:Recent research conducted in high-income countries suggests psychotic experiences are common in the general population, but evidence from low- and middle-income countries (LMIC) remains limited. Sri Lanka is a LMIC affected by three decades of civil conflict and, in 2004, a devastating tsunami. This study aimed to inv...

journal_title：Schizophrenia research

authors： Keraite A,Sumathipala A,Siriwardhana C,Morgan C,Reininghaus U

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Research participants must have adequate consent-related abilities to provide informed consent at the time of study enrollment. We sought to determine if research participants with schizophrenia maintain adequate consent-related abilities during a longitudinal study. If participants lose abilities during a tr...

journal_title：Schizophrenia research

authors： Stroup TS,Appelbaum PS,Gu H,Hays S,Swartz MS,Keefe RS,Kim SY,Manschreck TC,Boshes RA,McEvoy JP,Lieberman JA

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Neuropsychological impairment is common in schizophrenia and psychotic bipolar disorder. It has been hypothesized that the pathways leading to impairment differ between disorders. Cognitive impairment in schizophrenia is believed to result largely from atypical neurodevelopment, whereas bipolar disorder is i...

journal_title：Schizophrenia research

authors： Menkes MW,Armstrong K,Blackford JU,Heckers S,Woodward ND

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Widespread white matter abnormalities and alterations in glutamate levels have been reported in patients with schizophrenia. We hypothesized that alterations in white matter integrity and glutamate levels in individuals at clinical high risk (CHR) for psychosis are associated with the subsequent developmen...

journal_title：Schizophrenia research

authors： León-Ortiz P,Reyes-Madrigal F,Kochunov P,Gómez-Cruz G,Moncada-Habib T,Malacara M,Mora-Durán R,Rowland LM,de la Fuente-Sandoval C

更新日期：2020-06-25 00:00:00

abstract：OBJECTIVE:The comorbidity of schizophrenia and substance abuse is well documented and is remarkable for its prevalence and poor prognosis. While the etiology for this association is unknown, one possible mechanism relates to traumatic early life experiences, which have been shown to predispose individuals to both psych...

journal_title：Schizophrenia research

authors： Scheller-Gilkey G,Moynes K,Cooper I,Kant C,Miller AH

更新日期：2004-08-01 00:00:00

abstract：:This study was a preliminary open clinical trial aimed at exploring the hypothesis that estrogen may provide protection against schizophrenia in women. Eleven women with acute psychotic symptoms, as scored on the BPRS, SAPS and SANS, had 0.02 mg estradiol added to neuroleptic treatment for eight weeks. Their response ...

journal_title：Schizophrenia research

authors： Kulkarni J,de Castella A,Smith D,Taffe J,Keks N,Copolov D

更新日期：1996-07-05 00:00:00

abstract：OBJECTIVE:Many rating scales have been in use to evaluate various symptomatic domains, and eventually there are too many scales to be selected and widely utilized in busy real-world settings. Relevant, quick, and user-friendly assessment scales are needed to facilitate measurement-based treatment of schizophrenia. MET...

journal_title：Schizophrenia research

authors： Suzuki T,Uchida H,Nomura K,Takeuchi H,Nakajima S,Tanabe A,Yagi G,Watanabe K,Kashima H

更新日期：2008-12-01 00:00:00