当前位置： SCI文献检索 > SCHIZOPHRENIA RESEARCH期刊下所有文献 > EEG spectral power and negative symptoms in at-risk individuals predict transition to psychosis.

EEG spectral power and negative symptoms in at-risk individuals predict transition to psychosis.

Abstract：

INTRODUCTION:EEG power in the delta, theta and beta1 bands has been shown to be positively correlated with negative symptoms in first episode psychotic patients. The present study investigates this correlation in an "at risk mental state for psychosis" (ARMS) with the aim to improve prediction of transition to psychosis. METHODS:Thirteen ARMS patients with later transition to psychosis (ARMS-T) and fifteen without (follow-up period of at least 4 years) (ARMS-NT) were investigated using spectral resting EEG data (of 8 electrodes over the fronto-central scalp area placed according to the 10-20 system) and summary score of the Scale for the Assessment of Negative Symptoms (SANS). Linear regressions were used to evaluate the correlation of SANS and EEG power in seven bands (delta, theta, alpha1, alpha2, beta1, beta2, beta3) in both ARMS groups and logistic regressions were used to predict transition to psychosis. Potentially confounding factors were controlled. RESULTS:ARMS-T and ARMS-NT showed differential correlations of EEG power and SANS in delta, theta, and beta1 bands (p<.05): ARMS-T showed positive and ARMS-NT negative correlations. Logistic regressions showed that neither SANS score nor EEG spectral power alone predicted transition to psychosis. However, SANS score in combination with power in the delta, theta, beta1, and beta2 bands, respectively, predicted transition significantly (p<.03). CONCLUSIONS:ARMS-T and ARMS-NT show differential correlations of SANS summary score and EEG power in delta, theta, and beta bands. Prediction of transition to psychosis is possible using combined information from a negative symptom scale and EEG spectral data.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Zimmermann R,Gschwandtner U,Wilhelm FH,Pflueger MO,Riecher-Rössler A,Fuhr P

doi

10.1016/j.schres.2010.08.031

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

208-16

issue

2-3

eissn

0920-9964

issn

1573-2509

pii

S0920-9964(10)01502-1

journal_volume

123

pub_type

杂志文章

相关文献

SCHIZOPHRENIA RESEARCH文献大全
  • A dimensional comparison between delusional disorder, schizophrenia and schizoaffective disorder.

    abstract：INTRODUCTION:Since the early description of paranoia, the nosology of delusional disorder has always been controversial. The old idea of unitary psychosis has now gained some renewed value from the dimensional continuum model of psychotic symptoms. AIMS:1. To study the psychopathological dimensions of the psychosis sp...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2015.10.039

    authors： Muñoz-Negro JE,Ibanez-Casas I,de Portugal E,Ochoa S,Dolz M,Haro JM,Ruiz-Veguilla M,de Dios Luna Del Castillo J,Cervilla JA

    更新日期：2015-12-01 00:00:00

  • Childhood trauma as a risk factor for the onset of subclinical psychotic experiences: Exploring the mediating effect of stress sensitivity in a cross-sectional epidemiological community study.

    abstract：:Childhood trauma is a risk factor for the onset of schizophrenic psychosis. Because the psychosis phenotype can be described as a continuum with varying levels of severity and persistence, childhood trauma might likewise increase the risk for psychotic experiences below the diagnostic threshold. But the impact of stre...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2016.02.006

    authors： Rössler W,Ajdacic-Gross V,Rodgers S,Haker H,Müller M

    更新日期：2016-04-01 00:00:00

  • Trajectories of the course of schizophrenia: from progressive deterioration to amelioration over three decades.

    abstract：BACKGROUND:The extent of heterogeneity in the long-term course of schizophrenia is unclear. AIMS:To examine the course of schizophrenia in a population-based cohort. METHODS:This study included all Israeli individuals born in 1970-1988, of North African or European origin (N=2290), entered in the National Psychiatric...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2010.10.026

    authors： Levine SZ,Lurie I,Kohn R,Levav I

    更新日期：2011-03-01 00:00:00

  • Using self-determination theory to understand motivation deficits in schizophrenia: the 'why' of motivated behavior.

    abstract：:Self-determination theory (SDT) provides a model for understanding motivation deficits in schizophrenia, and recent research has focused on problems with intrinsic motivation. However, SDT emphasizes that motivated behavior results from three different factors: intrinsic motivators (facilitated by needs for autonomy, ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2014.04.027

    authors： Gard DE,Sanchez AH,Starr J,Cooper S,Fisher M,Rowlands A,Vinogradov S

    更新日期：2014-07-01 00:00:00

  • Cytokines in cerebrospinal fluid of patients with schizophrenia spectrum disorders: New data and an updated meta-analysis.

    abstract：:Few studies have been conducted examining cytokines in cerebrospinal fluid of patients compared to healthy volunteers. The goals of this study were: 1) to report original data detailing cytokine levels in the cerebrospinal fluid (CSF) of 10 patients with a schizophrenia spectrum disorder (SSD) diagnosis and 10 healthy...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.schres.2018.07.019

    authors： Gallego JA,Blanco EA,Husain-Krautter S,Madeline Fagen E,Moreno-Merino P,Del Ojo-Jiménez JA,Ahmed A,Rothstein TL,Lencz T,Malhotra AK

    更新日期：2018-12-01 00:00:00

  • Assessing intellectual functioning in persons with schizophrenia spectrum disorders using a seven subtest short form of the WAIS-R.

    abstract：:The purpose of this study was to examine the concurrent validity of a Wechsler Adult Intelligence Scale-Revised (WAIS-R) seven subtest short form. Researchers have shown that the IQ scores estimated by this short form correlate highly with full-form IQ scores in several patient populations. We compared the full WAIS-R...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/s0920-9964(97)00134-5

    authors： Iverson GL,Guirguis M,Green P

    更新日期：1998-03-10 00:00:00

  • Exposure to conflict and disaster: A national survey on the prevalence of psychotic experiences in Sri Lanka.

    abstract：:Recent research conducted in high-income countries suggests psychotic experiences are common in the general population, but evidence from low- and middle-income countries (LMIC) remains limited. Sri Lanka is a LMIC affected by three decades of civil conflict and, in 2004, a devastating tsunami. This study aimed to inv...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2016.01.026

    authors： Keraite A,Sumathipala A,Siriwardhana C,Morgan C,Reininghaus U

    更新日期：2016-03-01 00:00:00

  • Autoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feeling.

    abstract：:Autoimmunity, gastrointestinal (GI) disorders and schizophrenia have been associated with one another for a long time. This paper reviews these connections and provides a context by which multiple risk factors for schizophrenia may be related. Epidemiological studies strongly link schizophrenia with autoimmune disorde...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,评审

    doi：10.1016/j.schres.2014.06.027

    authors： Severance EG,Yolken RH,Eaton WW

    更新日期：2016-09-01 00:00:00

  • A role for endothelial NMDA receptors in the pathophysiology of schizophrenia.

    abstract：:Numerous genetic and postmortem studies link N-methyl-d-aspartate receptor (NMDAR) dysfunction with schizophrenia, forming the basis of the popular glutamate hypothesis. Neuronal NMDAR abnormalities are consistently reported from both basic and clinical experiments, however, non-neuronal cells also contain NMDARs, and...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2020.10.004

    authors： Intson K,Geissah S,McCullumsmith RE,Ramsey AJ

    更新日期：2020-11-11 00:00:00

  • Increased interleukin-2 serum levels were associated with psychopathological symptoms and cognitive deficits in treatment-resistant schizophrenia.

    abstract：:Accumulating evidence showed that interleukin-2 (IL-2) may be involved in the pathophysiology of schizophrenia. Increased IL-2 levels have been found in the serum of schizophrenia patients with mixed results. In the present study, we assessed serum IL-2 levels in a large group of 160 schizophrenia patients compared to...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2015.10.038

    authors： Tan Y,Li Y,Tan S,Wang Z,Yang FD,Cao B,Zunta-Soares GB,Soares JC,Zhang XY

    更新日期：2015-12-01 00:00:00

  • Insight in early psychosis: a 1-year follow-up.

    abstract：:Insight was investigated in 180 individuals consecutively admitted to a comprehensive early psychosis treatment program. Insight was assessed on admission and after 3, 6 and 12 months. Insight improved significantly over 12 months, and was negatively correlated with both positive and negative symptoms, and positively ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/S0920-9964(03)00047-1

    authors： Mintz AR,Addington J,Addington D

    更新日期：2004-04-01 00:00:00

  • Cognitive and brain function in schizotypal personality disorder.

    abstract：:Schizotypal personality disorder, a diagnosis defined partially in terms of a genetic relatedness to schizophrenia, has begun to receive extensive investigative study. While the exact etiologic relationship between schizotypal personality disorder and schizophrenia remains to be determined, three models have been cons...

    journal_title：Schizophrenia research

    pub_type：

    doi：10.1016/s0920-9964(01)00363-2

    authors： Siever LJ,Koenigsberg HW,Harvey P,Mitropoulou V,Laruelle M,Abi-Dargham A,Goodman M,Buchsbaum M

    更新日期：2002-03-01 00:00:00

  • Pronounced prefronto-temporal cortical thinning in schizophrenia: Neuroanatomical correlate of suicidal behavior?

    abstract：:Schizophrenia is characterized by increased mortality for which suicidality is the decisive factor. An analysis of cortical thickness and folding to further elucidate neuroanatomical correlates of suicidality in schizophrenia has not yet been performed. We searched for relevant brain regions with such differences betw...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2016.08.010

    authors： Besteher B,Wagner G,Koch K,Schachtzabel C,Reichenbach JR,Schlösser R,Sauer H,Schultz CC

    更新日期：2016-10-01 00:00:00

  • The effect of zonisamide on antipsychotic-associated weight gain in patients with schizophrenia: a randomized, double-blind, placebo-controlled clinical trial.

    abstract：BACKGROUND:Many patients with schizophrenia suffer from metabolic symptoms and weight gain in which predispose them to obesity, diabetes, and cardiovascular problems. This trial examines the efficacy and safety of zonisamide on weight and body mass index in patients with schizophrenia being administered with atypical a...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.schres.2013.03.021

    authors： Ghanizadeh A,Nikseresht MS,Sahraian A

    更新日期：2013-06-01 00:00:00

  • Family load estimates of schizophrenia and associated risk factors in a nation-wide population study of former child and adolescent patients up to forty years of age.

    abstract：OBJECTIVES:This nation-wide register-based study investigates the family load of schizophrenia (SZ) across three generations in affected families compared to control families. Furthermore the study compares the family load in case vs. control families considering the age of onset of the disorder in the cases. In additi...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2012.05.014

    authors： Helenius D,Munk-Jørgensen P,Steinhausen HC

    更新日期：2012-08-01 00:00:00

  • Antipsychotic drug use in pregnancy: A multinational study from ten countries.

    abstract：AIM:To compare the prevalence and trends of antipsychotic drug use during pregnancy between countries across four continents. METHODS:Individually linked health data in Denmark (2000-2012), Finland (2005-2014), Iceland (2004-2017), Norway (2005-2015), Sweden (2006-2015), Germany (2006-2015), Australia (New South Wales...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2020.03.048

    authors： Reutfors J,Cesta CE,Cohen JM,Bateman BT,Brauer R,Einarsdóttir K,Engeland A,Furu K,Gissler M,Havard A,Hernandez-Diaz S,Huybrechts KF,Karlstad Ø,Leinonen MK,Li J,Man KKC,Pazzagli L,Schaffer A,Schink T,Wang Z,Yu Y,

    更新日期：2020-06-01 00:00:00

  • Verbal memory impairment in healthy siblings of patients with schizophrenia.

    abstract：:Cognitive deficits have been recognized as a core feature of schizophrenia (SZ) and are present in most patients. Verbal memory (VM), working memory (WM), and executive function (EF) are domains commonly impaired in patients with SZ. These latter domains have been related to the genetic risk of the disorder characteri...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2013.08.019

    authors： Massuda R,Bücker J,Czepielewski LS,Narvaez JC,Pedrini M,Santos BT,Teixeira AS,Souza AL,Vasconcelos-Moreno MP,Vianna-Sulzbach M,Goi PD,Belmonte-de-Abreu P,Gama CS

    更新日期：2013-11-01 00:00:00

  • Who needs antipsychotic medication in the earliest stages of psychosis? A reconsideration of benefits, risks, neurobiology and ethics in the era of early intervention.

    abstract：:In recent years, early intervention services have attempted to identify people with a first episode of psychosis as early as possible, reducing the duration of untreated psychosis and changing the timing of delivery of interventions. The logic of early intervention is based partly on accessing people in a more treatme...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,评审

    doi：10.1016/j.schres.2010.02.1071

    authors： Francey SM,Nelson B,Thompson A,Parker AG,Kerr M,Macneil C,Fraser R,Hughes F,Crisp K,Harrigan S,Wood SJ,Berk M,McGorry PD

    更新日期：2010-06-01 00:00:00

  • Factor structure of the Brief Negative Symptom Scale.

    abstract：:The current study examined the factor structure of the Brief Negative Symptom Scale (BNSS), a next-generation negative symptom rating instrument developed in response to the NIMH-sponsored Consensus Development Conference on Negative Symptoms. Participants included 146 individuals with a DSM-IV diagnosis of schizophre...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2012.09.007

    authors： Strauss GP,Hong LE,Gold JM,Buchanan RW,McMahon RP,Keller WR,Fischer BA,Catalano LT,Culbreth AJ,Carpenter WT,Kirkpatrick B

    更新日期：2012-12-01 00:00:00

  • California Verbal Learning Test-II performance in schizophrenia as a function of ascertainment strategy: comparing the first and second phases of the Consortium on the Genetics of Schizophrenia (COGS).

    abstract：:The first phase of the Consortium on the Genetics of Schizophrenia (COGS-1) showed performance deficits in learning and memory on the California Verbal Learning Test, Second Edition (CVLT-II) in individuals with schizophrenia (SZ), compared to healthy comparison subjects (HCS). A question is whether the COGS-1 study, ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.schres.2014.10.029

    authors： Stone WS,Mesholam-Gately RI,Braff DL,Calkins ME,Freedman R,Green MF,Greenwood TA,Gur RE,Gur RC,Lazzeroni LC,Light GA,Nuechterlein KH,Olincy A,Radant AD,Siever LJ,Silverman JM,Sprock J,Sugar CA,Swerdlow NR,Tsuang DW

    更新日期：2015-04-01 00:00:00

  • Characterizing trajectories of cognitive functioning in older adults with schizophrenia: does method matter?

    abstract：BACKGROUND:Heterogeneity in clinical outcomes may be caused by factors working at multiple levels, e.g., between groups, between subjects, or within subjects over time. A more nuanced assessment of differences in variation among schizophrenia patients and between patients and healthy comparison subjects can clarify eti...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2012.10.033

    authors： Thompson WK,Savla GN,Vahia IV,Depp CA,O'Hara R,Jeste DV,Palmer BW

    更新日期：2013-01-01 00:00:00

  • Deficient prepulse inhibition in schizophrenia detected by the multi-site COGS.

    abstract：BACKGROUND:Startle inhibition by weak prepulses (PPI) is studied to understand the biology of information processing in schizophrenia patients and healthy comparison subjects (HCS). The Consortium on the Genetics of Schizophrenia (COGS) identified associations between PPI and single nucleotide polymorphisms in schizoph...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.schres.2013.12.004

    authors： Swerdlow NR,Light GA,Sprock J,Calkins ME,Green MF,Greenwood TA,Gur RE,Gur RC,Lazzeroni LC,Nuechterlein KH,Radant AD,Ray A,Seidman LJ,Siever LJ,Silverman JM,Stone WS,Sugar CA,Tsuang DW,Tsuang MT,Turetsky BI,Braff D

    更新日期：2014-02-01 00:00:00

  • Subcortical dysfunction in schizophrenia: a comparison with Parkinson's disease and Huntington's disease.

    abstract：:Neuropsychological performance in 20 chronic schizophrenic patients was contrasted to 25 Parkinson's disease, 12 Huntington's disease patients and 26 normal controls on measures shown to be sensitive to subcortical dysfunction. Some overlap was observed in the performance of the schizophrenic and basal ganglia groups ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/0920-9964(95)00069-0

    authors： Hanes KR,Andrewes DG,Pantelis C,Chiu E

    更新日期：1996-05-01 00:00:00

  • Do we need oxytocin to treat schizophrenia? A randomized clinical trial.

    abstract：BACKGROUND:Schizophrenia is a disabling complex mental disorder and despite all available treatment, many patients unfortunately remain partial- or non-responders. A large body of research has shown that oxytocin is an important prosocial peptide and there is initial evidence that the central oxytocin system is altered...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.schres.2016.02.011

    authors： Dagani J,Sisti D,Abelli M,Di Paolo L,Pini S,Raimondi S,Rocchi MB,Saviotti FM,Scocco P,Totaro S,Balestrieri M,de Girolamo G

    更新日期：2016-04-01 00:00:00

  • Impaired facilitation of self-control cognition by glucose in patients with schizophrenia: a randomized controlled study.

    abstract：OBJECTIVE:Studies in healthy individuals show that exerting self-control consumes cognitive resources, which reduces subsequent self-control performance. Restoring the availability of blood glucose eliminates this impairment. Patients with schizophrenia are found to have self-regulatory dysfunctions. This study aims to...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.schres.2014.03.010

    authors： Leung CM,Stone WS,Lee EH,Seidman LJ,Chen EY

    更新日期：2014-06-01 00:00:00

  • Self-esteem moderates affective and psychotic responses to social stress in psychosis: A virtual reality study.

    abstract：BACKGROUND:Higher liability to psychosis is associated with low self-esteem and increased sensitivity to social stress. Recently, we reported a positive relation between liability to psychosis and affective and psychotic responses to social stress. This study investigated how self-esteem moderates paranoia, peak subjec...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2018.06.042

    authors： Jongeneel A,Pot-Kolder R,Counotte J,van der Gaag M,Veling W

    更新日期：2018-12-01 00:00:00

  • The InterSePT scale for suicidal thinking reliability and validity.

    abstract：BACKGROUND:The InterSePT Scale for Suicidal Thinking (ISST) is a 12-item instrument for the assessment of current suicidal ideation in patients with schizophrenia and schizoaffective disorders. We report the psychometric characteristics of this new scale based on two studies. METHOD:In Study 1, 22 inpatients with schi...

    journal_title：Schizophrenia research

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/s0920-9964(02)00335-3

    authors： Lindenmayer JP,Czobor P,Alphs L,Nathan AM,Anand R,Islam Z,Chou JC,InterSePT Study Group.

    更新日期：2003-09-01 00:00:00

  • Negative symptoms in bipolar disorder and schizophrenia: A psychometric evaluation of the brief negative symptom scale across diagnostic categories.

    abstract：:Past studies have demonstrated that the Brief Negative Symptom Scale (BNSS) has excellent psychometric properties in patients with schizophrenia. In the current study, we extended this literature by examining psychometric properties of the BNSS in outpatients diagnosed with bipolar disorder (n=46), outpatients with sc...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2015.12.014

    authors： Strauss GP,Vertinski M,Vogel SJ,Ringdahl EN,Allen DN

    更新日期：2016-02-01 00:00:00

  • Low-frequency EEG oscillations associated with information processing in schizophrenia.

    abstract：:Numerous studies have described attenuated event-related potential (ERP) component amplitudes in schizophrenia (e.g., P300, Mismatch Negativity (MMN), Error Negativity/Error-Related Negativity (Ne/ERN)). Functional magnetic resonance imaging (fMRI) studies have typically shown decreased recruitment of diverse brain ar...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2009.09.036

    authors： Bates AT,Kiehl KA,Laurens KR,Liddle PF

    更新日期：2009-12-01 00:00:00

  • Failure to replicate the association between NRG1 and schizophrenia using Japanese large sample.

    abstract：:Systematic linkage disequilibrium (LD) mapping of 8p12-21 in the Icelandic population identified neuregulin 1 (NRG1) as a prime candidate gene for schizophrenia. However, results of replication studies have been inconsistent, and no large sample analyses have been reported. Therefore, we designed this study with the a...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2008.01.010

    authors： Ikeda M,Takahashi N,Saito S,Aleksic B,Watanabe Y,Nunokawa A,Yamanouchi Y,Kitajima T,Kinoshita Y,Kishi T,Kawashima K,Hashimoto R,Ujike H,Inada T,Someya T,Takeda M,Ozaki N,Iwata N

    更新日期：2008-04-01 00:00:00