Novel rating scales for schizophrenia - Targeted Inventory on Problems in Schizophrenia (TIP-Sz) and Functional Assessment for Comprehensive Treatment of Schizophrenia (FACT-Sz).

abstract：:Schizophrenia is characterized by increased mortality for which suicidality is the decisive factor. An analysis of cortical thickness and folding to further elucidate neuroanatomical correlates of suicidality in schizophrenia has not yet been performed. We searched for relevant brain regions with such differences betw...

journal_title：Schizophrenia research

authors： Besteher B,Wagner G,Koch K,Schachtzabel C,Reichenbach JR,Schlösser R,Sauer H,Schultz CC

更新日期：2016-10-01 00:00:00

abstract：:Structural abnormalities in the lateral prefrontal cortex (LPFC) are well-documented in schizophrenia and recent evidence suggests that these abnormalities relate to functional outcome. Cognitive control mechanisms, reliant on the LPFC, are impaired in schizophrenia and predict functional outcome, thus impaired cognit...

journal_title：Schizophrenia research

authors： Tully LM,Lincoln SH,Liyanage-Don N,Hooker CI

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:Emotion perception (EP) is impaired in schizophrenia, is stable across clinical state, resistant to antipsychotic treatment and linked to symptom severity. Given its pervasive nature, there is a need to quantitatively examine whether this dysfunction impacts functional outcomes. We used a meta-analytic str...

journal_title：Schizophrenia research

authors： Irani F,Seligman S,Kamath V,Kohler C,Gur RC

更新日期：2012-05-01 00:00:00

abstract：:Stigma may undermine the well-being of young people at risk of psychosis. We therefore measured self-labeling, stigma variables and well-being at baseline and again one year later among 77 at-risk participants. An increase in self-labeling during this period predicted heightened stigma stress after one year and a decr...

journal_title：Schizophrenia research

authors： Rüsch N,Müller M,Heekeren K,Theodoridou A,Metzler S,Dvorsky D,Corrigan PW,Walitza S,Rössler W

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Individuals with schizophrenia tend to have low levels of physical activity (PA) which contributes to high rates of physical comorbidities. Valid and reliable methods of assessing PA are essential for advancing health research. Ten years after initial validation of the Short-Form International Physical Activ...

journal_title：Schizophrenia research

authors： Duncan MJ,Arbour-Nicitopoulos K,Subramanieapillai M,Remington G,Faulkner G

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Cognitive Remediation (CR) is an evidence based treatment targeting cognitive and functional difficulties in people with psychosis. Despite the large number of effectiveness studies, only limited evidence exists for the active ingredients of this therapy. This study begins to fill this gap by exploring the r...

journal_title：Schizophrenia research

authors： Cella M,Wykes T

更新日期：2019-01-01 00:00:00

abstract：:The current study investigated whether a previously reported beneficial effect of methadone maintenance therapy (MMT) on antiretroviral adherence is also present in relation to antipsychotic treatment for schizophrenia. Administrative data were linked over a 17-year period for 1996 people who were dually diagnosed wit...

journal_title：Schizophrenia research

authors： Rezansoff SN,Moniruzzaman A,Somers JM

更新日期：2019-08-01 00:00:00

abstract：:The glutamatergic dysfunction hypothesis of schizophrenia implicates the genes involved in glutamatergic transmission as strong candidates for schizophrenia-susceptibility. Recent linkage and association studies have identified the glutamate receptor, ionotropic, delta 1 gene GRID1 on 10q22 as a strong candidate for s...

journal_title：Schizophrenia research

authors： Guo SZ,Huang K,Shi YY,Tang W,Zhou J,Feng GY,Zhu SM,Liu HJ,Chen Y,Sun XD,He L

更新日期：2007-07-01 00:00:00

abstract：:Social anhedonia is an important feature of schizophrenia and it is a promising indicator of schizotypy. Although social anhedonia is defined as an affective construct (less pleasure derived from social encounters), little is known about the emotional responsivity and expressivity of individuals with high levels of so...

journal_title：Schizophrenia research

authors： Leung WW,Couture SM,Blanchard JJ,Lin S,Llerena K

更新日期：2010-12-01 00:00:00

abstract：:A motivation is a telling hallmark of negative symptomatology in schizophrenia, and it impacts nearly every facet of behavior, including inclination to attempt the difficult cognitive tasks involved in cognitive remediation therapy. Experiences of external reward, reinforcement, and hedonic anticipatory enjoyment are ...

journal_title：Schizophrenia research

authors： Choi J,Medalia A

更新日期：2010-05-01 00:00:00

abstract：:Three-channel actometry was used to study neuroleptic-induced akathisia (NIA), a common and often serious disorder in association of traditional neuroleptic therapy. The aim was to explore the diagnostic possibilities of actometry in NIA and to examine in detail the motor phenomenology of the disorder in detail. The a...

journal_title：Schizophrenia research

authors： Tuisku K,Lauerma H,Holi M,Markkula J,Rimon R

更新日期：1999-11-30 00:00:00

abstract：:The performance of chronic schizophrenic probands (n=21), their first-degree schizotypal (22) and non-schizotypal (19) relatives, and normal controls (24), was measured in two associative learning paradigms, latent inhibition and the Kamin blocking effect. These paradigms assess the effects on learning of initial expo...

journal_title：Schizophrenia research

authors： Martins Serra A,Jones SH,Toone B,Gray JA

更新日期：2001-03-30 00:00:00

abstract：:By employing a novel semi-parametric extrapolation method, the life expectancies after the first hospitalization for schizophrenia and the associated lifetime healthcare expenditures were both estimated. Based on the linkage between the National Health Insurance Research Database and the National Mortality Registry of...

journal_title：Schizophrenia research

authors： Lêng CH,Chou MH,Lin SH,Yang YK,Wang JD

更新日期：2016-03-01 00:00:00

abstract：:In recent years, early intervention services have attempted to identify people with a first episode of psychosis as early as possible, reducing the duration of untreated psychosis and changing the timing of delivery of interventions. The logic of early intervention is based partly on accessing people in a more treatme...

journal_title：Schizophrenia research

authors： Francey SM,Nelson B,Thompson A,Parker AG,Kerr M,Macneil C,Fraser R,Hughes F,Crisp K,Harrigan S,Wood SJ,Berk M,McGorry PD

更新日期：2010-06-01 00:00:00

abstract：:The rubber-hand illusion (RHI), an illusion in which tactile sensations are referred to a synthetic alien limb, is enhanced in schizophrenia patients. Somatosensory evoked responses of the illusion were compared between schizophrenia patients and normal control subjects. Schizophrenia patients had significant alterati...

journal_title：Schizophrenia research

authors： Peled A,Pressman A,Geva AB,Modai I

更新日期：2003-11-15 00:00:00

abstract：:Haloperidol and reduced haloperidol plasma concentrations were measured in twelve schizophrenic patients upon cessation of haloperidol decanoate (HLD) treatment. Each patient received HLD 100 mg every 4 weeks for five injections. After the fifth injection, HLD was discontinued. Haloperidol and reduced haloperidol plas...

journal_title：Schizophrenia research

authors： Chang WH,Lin SK,Juang DJ,Chen LC,Yang CH,Hu WH,Chien CP,Lam YW,Jann MW

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:We aimed to examine the association between illicit substance use and age at onset in psychotic disorders in an Australian cohort. METHODS:Retrospectively acquired information on substance use during the year prior to illness onset was collected from 1642 participants enrolled in the Australian National 201...

journal_title：Schizophrenia research

authors： Stefanis NC,Dragovic M,Power BD,Jablensky A,Castle D,Morgan VA

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Appropriate expression of emotions and correct perception of emotional expression in others are important social skills which may be impaired in schizophrenia and contribute to poor social adjustment. We examined the relationship between expression of emotions as measured by affective flattening and other ne...

journal_title：Schizophrenia research

authors： Silver H,Shlomo N

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:A false sense of reality is a characteristic of schizophrenia spectrum disorders (SSD). Reality confusion may also emanate from posterior orbitofrontal cortex (OFC) lesions, as evident in confabulations that patients act upon and disorientation. This confusion can be measured by repeated runs of a continuous...

journal_title：Schizophrenia research

authors： Thézé R,Manuel AL,Pedrazzini E,Chantraine F,Patru MC,Nahum L,Guggisberg AG,Schnider A

更新日期：2019-02-01 00:00:00

abstract：:Social dysfunction is a hallmark of schizophrenia. Social isolation may increase individuals' risk for psychotic symptom exacerbation and relapse. Monitoring and timely detection of shifts in social functioning are hampered by the limitations of traditional clinic-based assessment strategies. Ubiquitous mobile technol...

journal_title：Schizophrenia research

authors： Buck B,Scherer E,Brian R,Wang R,Wang W,Campbell A,Choudhury T,Hauser M,Kane JM,Ben-Zeev D

更新日期：2019-06-01 00:00:00

abstract：:Various theories have been proposed to account for poor insight in schizophrenia. This study examined the relationships between insight, mood, schizophrenic symptoms and cognitive functioning. The relationship between longitudinal changes in insight and changes in symptoms and mood was also investigated. One-hundred p...

journal_title：Schizophrenia research

authors： Carroll A,Fattah S,Clyde Z,Coffey I,Owens DG,Johnstone EC

更新日期：1999-02-15 00:00:00

abstract：:CACNA1C (12p13.3) has been implicated as a susceptibility gene for schizophrenia by several replicated genome wide association studies. While these results have been consistent among studies in European populations, the findings in East Asian populations have varied. To test whether CACNA1C is a risk gene for schizoph...

journal_title：Schizophrenia research

authors： Zheng F,Zhang Y,Xie W,Li W,Jin C,Mi W,Wang F,Ma W,Ma C,Yang Y,Du B,Li K,Liu C,Wang L,Lu T,Zhang H,Wang Y,Lu L,Lv L,Zhang D,Yue W

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The presence of a psychosis continuum is suggested by studies showing that schizophrenia and non-clinical psychotic symptoms in the general population share the same risk factors. However, to our knowledge no large-scale studies have been conducted which examine the specificity of these risk factors in the g...

journal_title：Schizophrenia research

authors： Breetvelt EJ,Boks MP,Numans ME,Selten JP,Sommer IE,Grobbee DE,Kahn RS,Geerlings MI

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Altered motor behavior has consistently been reported in medication-naive adult patients with schizophrenia and first episode psychosis and adults at clinical high risk for psychosis (CHR). This study is the first to evaluate the prevalence of abnormal involuntary movements in a community sample of children ...

journal_title：Schizophrenia research

authors： Kindler J,Schultze-Lutter F,Michel C,Martz-Irngartinger A,Linder C,Schmidt SJ,Stegmayer K,Schimmelmann BG,Walther S

更新日期：2016-07-01 00:00:00

abstract：:An earlier age at onset of schizophrenia in men as opposed to women, has been widely reported, but hitherto, insufficient account has been taken of parameters that might confound this finding. Furthermore, few explanatory models have accounted for the differences in shape of the age-at-onset distributions in males and...

journal_title：Schizophrenia research

authors： Castle D,Sham P,Murray R

更新日期：1998-10-09 00:00:00

abstract：BACKGROUND:Advanced paternal age (APA) is associated with increased risk for schizophrenia, but its effect on treatment response has not been longitudinally studied. METHODS:Association of parental ages at the time of the child's birth with age of onset, initial symptom severity and treatment response (to placebo and ...

journal_title：Schizophrenia research

authors： Opler M,Malaspina D,Gopal S,Nuamah I,Savitz AJ,Singh J,Hough D

更新日期：2013-12-01 00:00:00

abstract：:Schizophrenia and affective disorders are relatively common neuropsychiatric diseases with a complex genetic etiology. A multigenic inheritance with variable influence of unknown environmental factors may be involved. Family studies have demonstrated the existence of both phenotypes in the same kindreds, and in certai...

journal_title：Schizophrenia research

authors： Wildenauer DB,Schwab SG,Maier W,Detera-Wadleigh SD

更新日期：1999-09-29 00:00:00

abstract：:Deficits in emotion perception are common in people with schizophrenia and current research has focused on improving these deficits. In our previous research, we demonstrated that directing attention to salient facial features via attention shaping can improve these deficits among inpatients. In this study, we examine...

journal_title：Schizophrenia research

authors： Combs DR,Chapman D,Waguspack J,Basso MR,Penn DL

更新日期：2011-04-01 00:00:00

abstract：:The objective of this study was to evaluate the efficacy, safety and tolerability of brexpiprazole versus placebo in adults with acute schizophrenia. This was a 6-week, multicenter, placebo-controlled double-blind phase 3 study. Patients with acute schizophrenia were randomized to brexpiprazole 1, 2 or 4 mg, or placeb...

journal_title：Schizophrenia research

authors： Kane JM,Skuban A,Ouyang J,Hobart M,Pfister S,McQuade RD,Nyilas M,Carson WH,Sanchez R,Eriksson H

更新日期：2015-05-01 00:00:00

abstract：:Schizophrenic delusions are important target symptoms for treatment. This study aims to identify predictors of delusion formation. Two samples of schizophrenic patients (total n = 131) are examined prospectively every second week during a period of 6 months. In one sample (n = 60) delusion formation (n = 27; 45%) is c...

journal_title：Schizophrenia research

authors： Jørgensen P

更新日期：1998-06-22 00:00:00