Pesticide poisonings in South Korea: findings from the National Hospital Discharge Survey 2004-2006.

abstract：:Diazinon is one of the most widely used organophosphate insecticides (OPI) in agriculture and public health programs. The aim of this study was to investigate how an OPI, diazinon, affects lipid peroxidation (LPO) and the antioxidant defense system in vitro. For this purpose, two experiments were carried out. In exper...

journal_title：Human & experimental toxicology

authors： Altuntas I,Kilinc I,Orhan H,Demirel R,Koylu H,Delibas N

更新日期：2004-01-01 00:00:00

abstract：:The phenomenon of subtoxic stimulation of organism response is not uncommon in aquatic toxicology experiments. We describe the presence of hormesis in both growth and reproduction experiments in aquatic toxicology where these responses are observed in both animals and plants and at different trophic levels of an ecosy...

journal_title：Human & experimental toxicology

authors： Bailer AJ,Oris JT

更新日期：1998-05-01 00:00:00

abstract：INTRODUCTION:Chronic obstructive pulmonary disease (COPD) due to sulfur mustard (SM), known as mustard lung, is an important late pulmonary complication of SM poisoning. Due to the possible role of systemic inflammation in mustard lung, we evaluated the serum levels of adiponectin and leptin in these patients. MATERIA...

journal_title：Human & experimental toxicology

authors： Rokni Yazdi H,Lari SM,Attaran D,Ayatollahi H,Mohsenizadeh A

更新日期：2014-06-01 00:00:00

abstract：:This report highlights a rare presentation of vitamin B(12) deficiency (concurrent psychotic disorder, seizures and hypertension). A 16-year-old girl presented with nervousness that had been persisting for 2 weeks. She had stopped eating and there was decreased self-care and she could not walk and sleep. Two days prio...

journal_title：Human & experimental toxicology

authors： Dogan M,Ariyuca S,Peker E,Akbayram S,Dogan ŞZ,Ozdemir O,Cesur Y

更新日期：2012-04-01 00:00:00

abstract：:The US Environmental Protection Agency (EPA) recently issued a Staff Paper that articulates current risk assessment practices. In section 4.1.3, EPA states, "... effects that appear to be adaptive, non-adverse, or beneficial may not be mentioned." This statement may be perceived as precluding risk assessments based on...

journal_title：Human & experimental toxicology

authors： Mundt KA

更新日期：2006-01-01 00:00:00

abstract：:4-hydroxynonenal (4-HNE) and 6-hydroxydopamine (6-OHDA)-mediated damage in dopaminergic neurons is well documented. Protective potential of steroidal hormone (17β-estradiol) has also been suggested. However, therapeutic potential of such promising hormone is hampered due to complex brain anatomy and physiology. Thus, ...

journal_title：Human & experimental toxicology

authors： Siddiqui MA,Kashyap MP,Al-Khedhairy AA,Musarrat J,Khanna VK,Yadav S,Pant AB

更新日期：2011-08-01 00:00:00

abstract：:The regulation of osteoblast proliferation is a key factor in maintaining bone mass. The enhancement of this process can be achieved by stimulating the proliferation of these cells. Mechanical stimulation is one of the important enhancing factors, but the exact cellular mechanisms of mechanical stimulation, i.e., mech...

journal_title：Human & experimental toxicology

authors： Rosenberg N

更新日期：2003-05-01 00:00:00

abstract：:Vulpinic acid, a lichen compound, has been shown to have many beneficial effects and its medicinal value increases day by day. As in atherosclerosis, endothelial damage is the basis of many diseases. The aim of this study is to investigate the effects of vulpinic acid against oxidative stress damage induced by hydroge...

journal_title：Human & experimental toxicology

authors： Sahin E,Dabagoglu Psav S,Avan I,Candan M,Sahinturk V,Koparal AT

更新日期：2019-06-01 00:00:00

abstract：:Manganese (Mn) is an essential nutrient required for proper growth and maintenance of numerous biological systems. At high levels it is known to be neurotoxic. While focused research concerning the transport of Mn across the blood-brain barrier (BBB) is on-going, the exact identity of the transporter(s) responsible is...

journal_title：Human & experimental toxicology

authors： Fitsanakis VA,Piccola G,Marreilha dos Santos AP,Aschner JL,Aschner M

更新日期：2007-04-01 00:00:00

abstract：:9-(4'-Aminophenyl)-9H-pyrido [3,4-b] indole (aminophenylnorharman, APNH) is a novel mutagenic heterocyclic amine, produced by the reaction of norharman with aniline in the presence of S9 mix. In the present study, the maternal and developmental toxicity of APNH were investigated in ICR mice administered oral doses of ...

journal_title：Human & experimental toxicology

authors： Naga T,Yoshimura S,Totsuka Y,Wakabayashi K

更新日期：2002-03-01 00:00:00

abstract：:Results obtained in long-term carcinogenicity studies with animals should be evaluated, first and foremost, by statistical comparisons of the data obtained from the treated group with that from the concurrent control group. Often the results are compared with data from so-called historical control groups in order to t...

journal_title：Human & experimental toxicology

authors： Greim H,Gelbke HP,Reuter U,Thielmann HW,Edler L

更新日期：2003-10-01 00:00:00

abstract：:This study was carried out on rodents, to explore the neurobehavioral effects of acrylonitrile (AN) administered in drinking water. Thirty, male, Sprague-Dawley rats were randomly divided into three groups: two exposure groups (50 and 200 ppm AN), and one control group (tap water without AN). Three tests, including th...

journal_title：Human & experimental toxicology

authors： Rongzhu L,Suhua W,Guangwei X,Fangan H,Ziqiang C,Fusheng J,Kacew S

更新日期：2007-03-01 00:00:00

abstract：:Occupational chronic solvent encephalopathy (CSE) is associated with a number of neurobehavioural disorders including defects of visual perception. The purpose of this study was to characterize colour vision defects in CSE patients. Colour vision was tested in bright illumination with the Farnsworth-Munsell 100-hue te...

journal_title：Human & experimental toxicology

authors： Päällysaho J,Näsänen R,Mäntyjärvi M,Kaukiainen A,Sainio M

更新日期：2007-04-01 00:00:00

abstract：:Periodontitis is a common infectious disease associated with destruction of periodontal ligaments and alveolar bones. CD4(+) T cell-mediated immune response is involved in the progression of periodontitis. Tobacco consumption increases the risk of periodontal disease. However, the impact of nicotine on the interaction...

journal_title：Human & experimental toxicology

authors： Ge X,Liu YF,Wong Y,Wu LZ,Tan L,Liu F,Wang XJ

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:The present study was designed to highlight the toxic impact of baclofen on both biochemical and histopathological aspects in rats' liver, gastric, lung, kidney, and brain tissues. METHODS:The study was performed on 30 healthy adult male albino rats divided into four groups with 5 rats in each control group,...

journal_title：Human & experimental toxicology

authors： Issa SY,Hafez EM,El-Banna AS,Abdel Rahman SM,AlMazroua MK,El-Hamd MA

更新日期：2018-04-01 00:00:00

abstract：:The present study was designed to evaluate the cardioprotective potential of lycopene (LCP) against isoproterenol (ISP)-induced myocardial infarction (MI), by assessing hemodynamic, biochemical and histopathological parameters. Wistar male albino rats were orally administered with LCP (0.5, 1.0 and 1.5 mg/kg) or with ...

journal_title：Human & experimental toxicology

authors： Ojha S,Goyal S,Sharma C,Arora S,Kumari S,Arya DS

更新日期：2013-05-01 00:00:00

abstract：:The polybrominated diphenyl ether flame retardants decabromodiphenyl ether (BDE-209) and bisphenol A (BPA) are environmental contaminants that can cross the placenta and exert toxicity in the developing fetal nervous system. Copy number variants (CNVs) play a role in a number of genetic disorders and may be implicated...

journal_title：Human & experimental toxicology

authors： Du L,Sun W,Li XM,Li XY,Liu W,Chen D

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Sulfur mustard (SM) is a chemical warfare agent that can cause serious pulmonary complications. This study was designed to determine serum highly sensitive C-reactive protein (hs-CRP) and evaluate its correlation with lung function parameters in patients with chronic obstructive pulmonary disease (COPD) due ...

journal_title：Human & experimental toxicology

authors： Attaran D,Lari SM,Khajehdaluee M,Ayatollahi H,Towhidi M,Asnaashari A,Marallu HG,Mazloomi M,Mood MB

更新日期：2009-12-01 00:00:00

abstract：:The effect of fendiline on cytosolic free Ca(2+) concentrations ([Ca(2+)](i)) and proliferation has not been explored in human oral cancer cells. This study examined whether fendiline altered Ca(2+) levels and caused cell death in OC2 human oral cancer cells. [Ca(2+)](i) and cell viability were measured using the fluo...

journal_title：Human & experimental toxicology

authors： Huang C,Huang C,Cheng J,Liu S,Chen I,Tsai J,Chou C,Tseng P,Jan C

更新日期：2009-01-01 00:00:00

abstract：:Lipid peroxidation is one of the main manifestations of oxidative damage and has been found to play an important role in the toxicity and carcinogenicity of many xenobiotics. In the present study, we investigated the possible induction of lipid peroxidation by aluminium in human foreskin fibroblast cultures by assayin...

journal_title：Human & experimental toxicology

authors： Anane R,Creppy EE

更新日期：2001-09-01 00:00:00

abstract：:Cytochrome P450 4B1 (CYP4B1) plays crucial roles in biotransforming of xenobiotics. Its predominant extrahepatic expression has been associated with certain tissue-specific toxicities. However, the expressions of CYP4B1 in various cancers and hence their potential roles in cancer development were inclusive. In this wo...

journal_title：Human & experimental toxicology

authors： Lim S,Alshagga M,Ong CE,Chieng JY,Pan Y

更新日期：2020-06-01 00:00:00

abstract：:1. Tobacco smoke contains around 4000 substances, most of which are described as toxic, and they may have an influence on the development of progeny. 2. The present studies concentrate on the measurement and calculation of indices describing the new-born's survival, rearing of pups, weight of foetuses, young animals, ...

journal_title：Human & experimental toxicology

authors： Florek E,Marszalek A,Biczysko W,Szymanowski K

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:The present work aimed to investigate the relationship between occupational exposure to airborne molds, serum aflatoxin B1 (AFB1), and liver enzymes of workers handling wheat flour. METHODS:The study included 90 bakers, 100 flour milling workers, and 100 controls with no exposure to flour dust. Workplace asp...

journal_title：Human & experimental toxicology

authors： Saad-Hussein A,Taha MM,Fadl NN,Awad AH,Mahdy-Abdallah H,Moubarz G,Aziz H,El-Shamy KA

更新日期：2016-01-01 00:00:00

abstract：:Inhalation of zinc fumes may lead to the acute respiratory distress syndrome. The mechanisms of pulmonary zinc toxicity are not yet understood. Therefore we investigated zinc-dependent depression of protein and RNA synthesis in rat and human lung cell lines. 1. After exposure to 120 or 150 micromol/l zinc, RNA synthes...

journal_title：Human & experimental toxicology

authors： Walther UI,Schulze J,Forth W

更新日期：1998-12-01 00:00:00

abstract：:Persistent organochlorine pollutants (POPs), such as polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs), dichloro diphenyl trichloroethane (DDT) and its major metabolite 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p' -DDE) have been associated with type 2 diabetes mellitus (T2DM) in rece...

journal_title：Human & experimental toxicology

authors： Rignell-Hydbom A,Rylander L,Hagmar L

更新日期：2007-05-01 00:00:00

abstract：:Benzydamine is a nonsteroidal anti-inflammatory drug, currently available as mouthwash, aerosol, dermal cream, vaginal douche preparation, pills and otic drops. Up to now no cases of poisoning due to this drug have been reported. A 6-year-old girl with an accidental poisoning with benzydamine is described. The episode...

journal_title：Human & experimental toxicology

authors： Gómez-López L,Hernández-Rodríguez J,Pou J,Nogué S

更新日期：1999-07-01 00:00:00

abstract：:The use of Lucilia sericata larvae on the healing of wounds in diabetics has been reported. However, the role of the excretion/secretion (ES) products of the larvae in treatment of diabetic wounds remains unknown. This study investigated whether application of the ES products of L. sericata on the wound surface could ...

journal_title：Human & experimental toxicology

authors： Tombulturk FK,Kasap M,Tuncdemir M,Polat E,Sirekbasan S,Kanli A,Kanigur-Sultuybek G

更新日期：2018-05-01 00:00:00

abstract：:The second-generation selective 5-HT2 receptor antagonists and reuptake inhibitors (SARIs) class antidepressants are known to have fewer cardiovascular side effects than the older ones. However, several case reports showed that trazodone, one of the second-generation SARIs, induces QT prolongation, cardiac arrhythmia,...

journal_title：Human & experimental toxicology

authors： Lee S,Lee HA,Kim SJ,Kim KS

更新日期：2016-05-01 00:00:00

abstract：:1. Four different concentrations of quinalphos and methyl parathion were tested on human peripheral lymphocytes over different time periods, for the analysis of chromosomal aberrations and sister chromatid exchanges (SCEs). 2. A significant increase in chromosomal aberrations was observed when cells were treated with ...

journal_title：Human & experimental toxicology

authors： Rupa DS,Reddy PP,Reddi OS

更新日期：1990-11-01 00:00:00

abstract：:1. This work examines the influence of age on some nephrotoxic signs of gentamicin in normal and diabetic rats (aged 1 and 24 months). 2. Gentamicin (80 mg-1 kg-1 day for 6 days, intramuscularly) produced the typical pattern of nephrotoxicity; significantly increasing the plasma concentrations of creatinine and urea, ...

journal_title：Human & experimental toxicology

authors： Ali BH,Bashir AK,Mugamer IT,Tanira MO

更新日期：1996-01-01 00:00:00