Cytogeneticity of quinalphos and methyl parathion in human peripheral lymphocytes.

abstract：:HCH isomers, endosulfan, malathion, chlorpyrifos, and methyl-parathion were monitored in human milk samples from Bhopal, Madhya Pradesh. The endosulfan concentrations were highest and exceeded the sigma-HCH, chlorpyrifos, and malathion concentrations by 3.5-, 1.5-, and 8.4-fold, respectively. Through breast milk, infa...

journal_title：Human & experimental toxicology

authors： Sanghi R,Pillai MK,Jayalekshmi TR,Nair A

更新日期：2003-02-01 00:00:00

abstract：:1. Dettol liquid (chloroxylenol 4.8%, pine oil, isopropyl alcohol), a household disinfectant, has a corrosive action on the gastrointestinal mucosa when swallowed. The incidence of upper gastrointestinal haemorrhage and gastroscopic findings following Dettol poisoning was studied in 89 patients. 2. Five patients (5.6%...

journal_title：Human & experimental toxicology

authors： Chan TY,Sung JJ,Critchley JA

更新日期：1995-01-01 00:00:00

abstract：:In this study, the effect of a combination of vitamin C, vitamin E and selenium on ethanol-induced duodenal mucosal damage in rats was investigated morphologically and biochemically. The duodenal mucosal injury was produced by oral administration of 1 mL of absolute ethanol to each rat. Animals received vitamin C (250...

journal_title：Human & experimental toxicology

authors： Koyuturk M,Bolkent S,Ozdil S,Arbak S,Yanardag R

更新日期：2004-08-01 00:00:00

abstract：:This report highlights a rare presentation of vitamin B(12) deficiency (concurrent psychotic disorder, seizures and hypertension). A 16-year-old girl presented with nervousness that had been persisting for 2 weeks. She had stopped eating and there was decreased self-care and she could not walk and sleep. Two days prio...

journal_title：Human & experimental toxicology

authors： Dogan M,Ariyuca S,Peker E,Akbayram S,Dogan ŞZ,Ozdemir O,Cesur Y

更新日期：2012-04-01 00:00:00

abstract：:Fructus Psoraleae (FP), widely used in traditional medicine, is increasingly reported to cause serious hepatotoxicity in recent years. However, the main toxic constituents responsible for hepatotoxicity and the underlying mechanisms are poorly understood. In the present study, psoralen, a main and quality-control cons...

journal_title：Human & experimental toxicology

authors： Huang J,Wang Q,Chen M,Bi Y,Shi H,Zhou K

更新日期：2020-12-15 00:00:00

abstract：BACKGROUND:The mortality rate associated with human glufosinate poisoning is high. We evaluated the usefulness of serum ammonia and sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation II (APACHE II) scores for early prediction of in-hospital mortality in glufosinate ammonium po...

journal_title：Human & experimental toxicology

authors： Lee J,Lee Y,Kim YS,Choi JG,Go TH,Kim H,Cha YS

更新日期：2019-09-01 00:00:00

abstract：:Accumulating evidence has shown that ethanol-induced iron overload plays a crucial role in the development and progression of alcoholic liver disease. We designed the present study to investigate the potential protective effect of quercetin, a naturally occurring iron-chelating antioxidant on alcoholic iron overload a...

journal_title：Human & experimental toxicology

authors： Li Y,Deng Y,Tang Y,Yu H,Gao C,Liu L,Liu L,Yao P

更新日期：2014-05-01 00:00:00

abstract：:Pesticides, including organophosphate (OP), organochlorine (OC), and carbamate (CB) compounds, are widely used in agricultural and indoor purposes. OP and CB act as acetyl cholinesterase (AChE) inhibitors that affect lots of organs such as peripheral and central nervous systems, muscles, liver, pancreas, and brain, wh...

journal_title：Human & experimental toxicology

authors： Karami-Mohajeri S,Abdollahi M

更新日期：2011-09-01 00:00:00

abstract：:This study was designed to determine the levels of prolactin, leptin, osteopontin, and follistatin in workers chronically and subacutely exposed to lead compounds. The examined population consisted of three groups. The first group was composed of 56 male workers who were chronically exposed to lead for 13.38 ± 10.38 y...

journal_title：Human & experimental toxicology

authors： Dobrakowski M,Kasperczyk A,Czuba ZP,Machoń-Grecka A,Szlacheta Z,Kasperczyk S

更新日期：2017-06-01 00:00:00

abstract：:Tissue-dependent oestrogenic and anti-oestrogenic activity of polycyclic aromatic hydrocarbons (PAHs) has been suggested. In this study, the effect of two PAH mixtures, M1 composed of all 16 priority pollutants and M2 composed of five (noted in the highest levels) compounds, on follicle-stimulating hormone receptor (F...

journal_title：Human & experimental toxicology

authors： Zajda K,Gregoraszczuk EL

更新日期：2020-03-01 00:00:00

abstract：:The purpose of this study was to characterize the zinc oxide nanoparticles (ZnO-NPs) and their bulk counterpart in suspensions and to access the impact of their acute oral toxicity at doses of 300 and 2000 mg/kg in healthy female Wistar rats. The hematological, biochemical, and urine parameters were accessed at 24 and...

journal_title：Human & experimental toxicology

authors： Srivastav AK,Kumar M,Ansari NG,Jain AK,Shankar J,Arjaria N,Jagdale P,Singh D

更新日期：2016-12-01 00:00:00

abstract：:Neutrophil functions were studied in 38 lead-exposed workers compared to 34 controls. Both groups were matched according to age, sex, drinking and smoking habits, ethnic origin and drug intake. Blood lead levels were found to be seven times higher in exposed workers than in controls. Phagocytosis assayed by chemilumin...

journal_title：Human & experimental toxicology

authors： Bergeret A,Pouget E,Tedone R,Meygret T,Cadot R,Descotes J

更新日期：1990-07-01 00:00:00

abstract：:Seafood is considered by nutritionists to be a high source of omega 3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs) which are involved in prevention of cardiovascular diseases. The aim of the present study is firstly to detect the presence of organochlorine pesticides and heavy metals in some fresh seafood of ...

journal_title：Human & experimental toxicology

authors： Al-Malki AL,Moselhy SS

更新日期：2011-10-01 00:00:00

abstract：INTRODUCTION:Poisoning from organophosphates and carbamates is a significant cause of morbidity and mortality worldwide. Concerns have been expressed over the safety and efficacy of the use of oximes such as pralidoxime (2-PAM) in patients with carbamate poisoning in general, and more so with carbaryl poisoning specifi...

journal_title：Human & experimental toxicology

authors： Mercurio-Zappala M,Hack JB,Salvador A,Hoffman RS

更新日期：2007-02-01 00:00:00

abstract：:This study was designed to evaluate the maternal toxicity and teratogenicity of fenproporex, one of the most widely-used anorectic drugs in many countries, including Brazil. Three periods of exposure were evaluated: (a) 30 days before mating; (b) from gestational day (GD) 0 to 14; and (c) 30 days before mating and dur...

journal_title：Human & experimental toxicology

authors： Moreira CQ,Faria MJ,Baroneza JE,Oliveira RJ,Moreira EG

更新日期：2005-08-01 00:00:00

abstract：:Accidental ingestion of electrical batteries occurs commonly in children. This rarely is associated with severe morbidity and mortality. Significant symptoms can arise due to leakage of alkali or heavy metals from the battery after degradation in the gastrointestinal tract. The main heavy metal of concern in electrica...

journal_title：Human & experimental toxicology

authors： Mallon PT,White JS,Thompson RL

更新日期：2004-04-01 00:00:00

abstract：:The isolated and identified triterpenoid, 1-hydroxytetratriacontane-4-one (C34H68O2), obtained from the methanolic leaf extract of Leucas aspera Linn. was explored for the first time for antisnake venom activity. The plant (L. aspera Linn.) extract significantly antagonized the spectacled cobra (Naja naja naja) venom ...

journal_title：Human & experimental toxicology

authors： Venkatesan C,Sarathi M,Balasubramanian G,Thomas J,Balachander V,Babu VS,Bilal SM,Majeed SA,Madan N,Raj NS,Vimal S,Nambi KS,Hameed AS

更新日期：2014-04-01 00:00:00

abstract：:The present study was designed to evaluate the cardioprotective potential of lycopene (LCP) against isoproterenol (ISP)-induced myocardial infarction (MI), by assessing hemodynamic, biochemical and histopathological parameters. Wistar male albino rats were orally administered with LCP (0.5, 1.0 and 1.5 mg/kg) or with ...

journal_title：Human & experimental toxicology

authors： Ojha S,Goyal S,Sharma C,Arora S,Kumari S,Arya DS

更新日期：2013-05-01 00:00:00

abstract：INTRODUCTION:Accidental toxicity by organophosphate (OP) agents may occur among farmers during spraying season due to improper use and handling. Plasma cholinesterase (ChE) activity measurement is recommended to monitor the extent of exposure to the OP agent. The aim of the current study was to measure plasma ChE activ...

journal_title：Human & experimental toxicology

authors： Pakravan N,Shokrzadeh M,Bari MA,Shadboorestan A

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Mushroom poisoning is still a significant health-care problem, with the potential to affect blood parameters. The present study analyses the effect of mushroom poisoning on complete blood cell parameters, cell ratios, and cell volume indices and the effect of the mentioned parameters on prognosis/hospital len...

journal_title：Human & experimental toxicology

authors： Doğan M,Karahan I

更新日期：2019-10-01 00:00:00

abstract：:Dimerized translationally controlled tumor protein (dTCTP) plays a role in allergic diseases. A 7-mer peptide, dimerized translationally binding protein 2 (dTBP2), binds to dTCTP and inhibits dTCTP, suggesting that the 7-mer peptide may have therapeutic potential. We assessed the safety of dTBP2 by examining its cytot...

journal_title：Human & experimental toxicology

authors： Kim M,Jin YB,Lee K,Lee YS

更新日期：2013-11-01 00:00:00

abstract：:Changes required for the explicit recognition of hormesis are outlined for both ecotoxicology and ecological risk assessment (ERA). A major research need is the extension of hormesis beyond chemical stressors to abiotic (e.g., habitat) and biotic stressors (e.g., species introductions, organism interactions). An overr...

journal_title：Human & experimental toxicology

authors： Chapman PM

更新日期：2001-10-01 00:00:00

abstract：:Sterigmatocystin (Stg), a major secondary metabolite of Aspergillus versicolor and A. nidulans, is the precursor of aflatoxin B1. In this study, male albino rats were treated with Stg-contaminated diet for 30 days, resulting in reduced levels of glutathione, ascorbic acid, and alpha-tocopherol. The activity of catalas...

journal_title：Human & experimental toxicology

authors： Sivakumar V,Thanislass J,Niranjali S,Devaraj H

更新日期：2001-08-01 00:00:00

abstract：:Morphine-6-glucuronide, the active metabolite of morphine, and to a lesser extent morphine itself are known to accumulate in patients with renal failure. A number of cases on non-lethal morphine toxicity in patients with renal impairment report high plasma concentrations of morphine-6-glucuronide, suggesting that this...

journal_title：Human & experimental toxicology

authors： Lagas JS,Wagenaar JF,Huitema AD,Hillebrand MJ,Koks CH,Gerdes VE,Brandjes DP,Beijnen JH

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Deliberate self-poisoning (DSP) is a major health problem with increasing incidence mainly among young people. OBJECTIVE:To examine the clinical and toxicological characteristics of DSP, it is compared to unintentional (non-DSP) exposures and those characteristics which might be associated with increased to...

journal_title：Human & experimental toxicology

authors： Bentur Y,Raikhlin-Eisenkraft B,Lavee M

更新日期：2004-07-01 00:00:00

abstract：:This report describes two accidents, involving snakes of the Micrurus corallinus species, where compromising respiratory function was not observed and the specific anti-elapidic serum was the single therapy used, and a third incident, probably involving Micrurus frontalis, where neostigmine was used to remedy respirat...

journal_title：Human & experimental toxicology

authors： Coelho LK,Silva E,Espositto C,Zanin M

更新日期：1992-03-01 00:00:00

abstract：:A key aim of toxicology is the prevention of adverse effects due to toxic hazards. Therefore, the dissemination of toxicology research findings must confront two important challenges: one being the lack of information on the vast majority of potentially toxic industrial chemicals and the other being the strict criteri...

journal_title：Human & experimental toxicology

authors： Grandjean P

更新日期：2015-12-01 00:00:00

abstract：:Derivatives of dehydrocrotonin (DHC; Compound I) with different anti-ulcerogenic properties but less toxicity were produced by reducing the cyclohexenone moiety of DHC with NaBH4 (Compound II), reducing the cyclohexenone and lactone moieties with LiAlH4 (Compound III) and transforming the lactone moiety into an amide ...

journal_title：Human & experimental toxicology

authors： Melo PS,Durán N,Haun M

更新日期：2002-05-01 00:00:00

abstract：:The National Toxicology Program (NTP) Technical Reports online database was reviewed to find chemicals that were reported to show clear evidence of carcinogenicity in the NTP rodent studies and for which data on human exposure could be found. Six representative compounds were selected. Three volatile compounds: ethyl ...

journal_title：Human & experimental toxicology

authors： Waddell WJ

更新日期：2003-09-01 00:00:00

abstract：:Diazinon is one of the most widely used organophosphate insecticides (OPI) in agriculture and public health programs. The aim of this study was to investigate how an OPI, diazinon, affects lipid peroxidation (LPO) and the antioxidant defense system in vitro. For this purpose, two experiments were carried out. In exper...

journal_title：Human & experimental toxicology

authors： Altuntas I,Kilinc I,Orhan H,Demirel R,Koylu H,Delibas N

更新日期：2004-01-01 00:00:00