Ethics in biotechnology and biosecurity.

Abstract:

:Great advances in technology produce unique challenges. Every technology also has a dual use, which needs to be understood and managed to extract maximum benefits for mankind and the development of civilization. The achievements of physicists in the mid-20th century resulted in the nuclear technology, which gave us the destructive power of the atomic bomb as also a source of energy. Towards the later part of the 20th century, information technology empowered us with fast, easy and cheap access to information, but also led to intrusions into our privacy. Today, biotechnology is yielding life- saving and life-enhancing advances at a fast pace. But, the same tools can also give rise to fiercely destructive forces. How do we construct a security regime for biology? What have we learnt from the management of earlier technological advances? How much information should be in the public domain? Should biology, or more broadly science, be regulated? Who should regulate it? These and many other ethical questions need to be addressed.

journal_name

Indian J Med Microbiol

authors

Jameel S

doi

10.4103/0255-0857.90155

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

331-5

issue

4

eissn

0255-0857

issn

1998-3646

pii

IndianJMedMicrobiol_2011_29_4_331_90155

journal_volume

29

pub_type

杂志文章,评审
  • Detection of mutation in isoniazid-resistant Mycobacterium tuberculosis isolates from tuberculosis patients in Belarus.

    abstract::The aim of this study was to investigate the frequency, location and type of katG mutations in Mycobacterium tuberculosis strains isolated from patients in Belarus. Forty two isoniazid-resistant isolates were identified from sputum of 163 patients with active pulmonary tuberculosis. Drug susceptibility testing was det...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.40528

    authors: Bostanabad SZ,Titov LP,Bahrmand A,Nojoumi SA

    更新日期:2008-04-01 00:00:00

  • Pyopericardium due to group D streptococcus.

    abstract::Beta-hemolytic Enterococcus faecalis was isolated from the pericardial fluid obtained from a patient with pyopericardium. The patient was immunocompetent and had mild pleural effusion. He was treated with parenteral co-amoxiclav and amikacin, had underwent pericardiectomy with repeated pericardial aspiration, and reco...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.38870

    authors: Karthikeyan K,Rajesh KR,Poornima H,Bharathidasan R,Brahmadathan KN,Priyadharsini RI

    更新日期:2008-01-01 00:00:00

  • Cutaneous leishmaniasis: an emerging infection in a non-endemic area and a brief update.

    abstract::We report here the emergence of a new focus of cutaneous leishmaniasis (CL) due to Leishmania tropica (L. tropica) in the Ajmer city of Rajasthan, India, a previously non-endemic area. Between January-February 2006, 13 new indigenously acquired cases of CL were diagnosed among the patients attending the Skin and STD d...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.34774

    authors: Rastogi V,Nirwan PS

    更新日期:2007-07-01 00:00:00

  • Molecular characterisation of antimicrobial resistance in Pseudomonas aeruginosa and Acinetobacter baumannii during 2014 and 2015 collected across India.

    abstract:BACKGROUND:Surveillance of antimicrobial resistance (AMR) is of great importance. Pseudomonas aeruginosa and Acinetobacter baumannii are important pathogens and emergence of resistance in these have increased the morbidity and mortality rates. This surveillance study was initiated by the Government of India - Indian Co...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,多中心研究

    doi:10.4103/0255-0857.195376

    authors: Pragasam AK,Vijayakumar S,Bakthavatchalam YD,Kapil A,Das BK,Ray P,Gautam V,Sistla S,Parija SC,Walia K,Ohri VC,Anandan S,Veeraraghavan B

    更新日期:2016-10-01 00:00:00

  • Assessment of trends of ofloxacin resistance in Mycobacterium tuberculosis.

    abstract:PURPOSE:Ofloxacin (OFX) is one of the potent fluoroquinolone (FQ) recommended to treat MDR-TB. Over a decade, the preexposure of this drug for the treatment of other bacterial infections has resulted in acquisition of FQ resistance among Mycobacterium tuberculosis strains. Considering this possibility, a study was unde...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.83913

    authors: Verma JS,Nair D,Rawat D,Manzoor N

    更新日期:2011-07-01 00:00:00

  • Comparison of nested polymerase chain reaction and real-time polymerase chain reaction targeting 47kda gene for the diagnosis of scrub typhus.

    abstract:Introduction:Scrub typhus is a zoonotic infection caused by Orientia tsutsugamushi which is transmitted by Leptotrombidium mites. The disease manifests as a mild-to-severe illness with non-specific clinical symptoms. Rapid diagnosis and prompt treatment are essential for patient management. Both serological and molecul...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_19_170

    authors: Srinivasan S,Kalaimani S,Jude Prakash JA,Menon T

    更新日期:2019-01-01 00:00:00

  • Epidemiology and risk factors associated with NTM pulmonary and extrapulmonary infections in a high tuberculosis endemic Region.

    abstract:Introduction:Non-tuberculous mycobacteria, although identified as pathogenic to humans long time ago, are emerging as the new threat in the past two decades. Even in tuberculosis endemic country such as India, they are being isolated from the clinical specimens more often than previously. This change in trend is of con...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_20_274

    authors: Wani SR,Wattal C,Raveendran R

    更新日期:2020-04-01 00:00:00

  • Severe acute respiratory syndrome.

    abstract::Severe acute respiratory syndrome (SARS) is a form of atypical pneumonia that apparently originated in Guangdong Province of the People's Republic of China in late 2002. This first came to the world's attention in late February 2003, and has since spread worldwide. As of June 23rd 2003, the disease had been reported f...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Thomas PA

    更新日期:2003-07-01 00:00:00

  • Trichosporon asahii as an emerging etiologic agent of disseminated trichosporonosis: a case report and an update.

    abstract:PURPOSE:To report a fatal case of disseminated trichosporonosis caused by Trichosporon asahii in a patient with acute myeloblastic leukemia (AML) and to present an update on systemic trichosporonosis with special reference to India. METHODS:The diagnosis was based on repeated demonstration of budding yeast cells and a...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Chowdhary A,Ahmad S,Khan ZU,Doval DC,Randhawa HS

    更新日期:2004-01-01 00:00:00

  • Disseminated cryptococcosis in a patient with nephrotic syndrome.

    abstract::Disseminated cryptococcosis mainly occurs in patients with impaired cell mediated immunity. We present a case of disseminated cryptococcosis in a non-HIV patient with nephrotic syndrome who never received immunosuppression. Cultures of bone marrow aspirate, cerebrospinal fluid analysis and histology of skin lesions we...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.25209

    authors: Qadir F,Manzoor K,Ahmed E

    更新日期:2006-04-01 00:00:00

  • Pre-transplant cytomegalovirus immunoglobulin G antibody levels could prevent severe cytomegalovirus infections post-transplant in liver transplant recipients: Experience from a tertiary care liver centre.

    abstract:BACKGROUND:Humoral immune responses in cytomegalovirus (CMV) are not studied well. Pre-transplant CMV immunoglobulin G (IgG) antibody levels (Pre-Tx IgG) could influence the occurrence of post-transplant CMV infections. OBJECTIVE:Correlation between pre-Tx IgG and post-Tx risk of acquiring CMV infection was investigat...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_17_201

    authors: Gupta E,Pamecha V,Verma Y,Kumar N,Rastogi A,Hasnian N,Bhadoria AS

    更新日期:2017-10-01 00:00:00

  • Nanotechnology: a new frontier in virus detection in clinical practice.

    abstract::Researchers are expanding the applications of nanotechnology in the field of medicine since mid-2000. These technologies include nanoarrays, protein arrays, nanopore technology, nanoparticles as a contrivance in immunoassays and nanosensors, among others. Nanobiotechnologies are clinically applicable and possess the p...

    journal_title:Indian journal of medical microbiology

    pub_type: 社论,评审

    doi:

    authors: Abraham AM,Kannangai R,Sridharan G

    更新日期:2008-10-01 00:00:00

  • Refractory giardiasis: a molecular appraisal from a tertiary care centre in India.

    abstract:PURPOSE:The intestinal flagellate Giardia lamblia includes many genetically distinct assemblages, of which assemblage A and B, predominantly infect humans. Nitroimidazoles derivatives (metronidazole and tinidazole) and nitazoxanide are some of the therapeutic agents for treatment of giardiasis. Nevertheless, some indiv...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.142236

    authors: Yadav P,Tak V,Mirdha BR,Makharia GK

    更新日期:2014-10-01 00:00:00

  • Extended spectrum beta lactamase (ESBL) mediated resistance to third generation cephalosporins among Klebsiella pneumoniae in Chennai.

    abstract:PURPOSE:To examine the incidence of extended spectrum b lactamase (ESbL) producing strains and multidrug resistant strains of Klebsiella pneumoniae isolated from children between 0-5 years of age. METHODS:Multidrug resistance and ESbL production was studied in a total of 120 isolates of Klebsiella pneumoniae obtained ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Subha A,Ananthan S

    更新日期:2002-04-01 00:00:00

  • Review of a 7-year record of the bacteriological profile of airway secretions of children with cystic fibrosis in North India.

    abstract:Background:Cystic fibrosis (CF) is now a recognised entity in India, with prevalence rates between 1/10,000 and 1/50,000. However, no data were available with regard to the profile of respiratory pathogens in the Indian setting. Materials and Methods:The records of respiratory secretion bacterial cultures of children ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_18_424

    authors: Gautam V,Kaza P,Mathew JL,Kaur V,Sharma M,Ray P

    更新日期:2019-04-01 00:00:00

  • Unimicrobial appendicitis due to non-vaccine serotype of streptococcus pneumoniae: Implications for and management and prevention.

    abstract::The aetiology of appendicitis is usually polymicrobial. We report a rare case of appendicitis caused by Streptococcus pneumoniae as the only causative organism. The case assumes significance because it occurs in the absence of any predisposing factor for invasive pneumococcal infection, it is unimicrobial, it may lead...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Bhattacharya S,Kanungo R,Natarajan MK,Mahalakshmi VN,Srinivasan K

    更新日期:2001-04-01 00:00:00

  • Pneumococcusuria: From bench to bedside.

    abstract::The present study highlights six cases of pneumococcusuria during the time period of May 2008 to May 2010. All the patients had a co-existing predisposing factor with the isolation of Streptococcus pneumoniae in urine. Five of the six patients having signs and symptoms of urinary tract infections (UTI) were treated an...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.93056

    authors: Krishna S,Sanjeevan KV,Sudheer A,Dinesh KR,Kumar A,Karim S

    更新日期:2012-01-01 00:00:00

  • Identification of opportunistic enteric parasites among immunocompetent patients with diarrhoea from Northern India and genetic characterisation of Cryptosporidium and Microsporidia.

    abstract:PURPOSE:Enteric parasitic infestation is a major public health problem in developing countries. Parasites such as Cryptosporidium spp., Cyclospora spp., Cystoisospora spp. and Microsporidia may cause severe diarrhoea among immunocompromised patients. There is scanty data on their frequency among immunocompetent patient...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.174114

    authors: Ghoshal U,Dey A,Ranjan P,Khanduja S,Agarwal V,Ghoshal UC

    更新日期:2016-01-01 00:00:00

  • Antimicrobial susceptibility testing in India - a status survey.

    abstract::Resistance to a variety of antimicrobial agents is emerging in bacterial pathogens throughout the world. Since the accuracy of the antimicrobial susceptibility data is associated with the performance standard of the test, strict adherence to the standard procedures is essential. The Kirby-Bauer disc diffusion suscepti...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Sudha V,Prasad A,Khare S,Bhatia R

    更新日期:2001-10-01 00:00:00

  • Management of post-operative Nocardia endophthalmitis.

    abstract::Post-operative Nocardia endophthalmitis has an aggressive course and poor visual prognosis. It often masquerades as severe post-operative uveitis or toxic anterior segment syndrome due to the absence of vitreous involvement resulting in a delay in diagnosis. The poor prognosis in Nocardia endophthalmitis is due to sev...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.99506

    authors: Pradhan ZS,Jacob P,Korah S

    更新日期:2012-07-01 00:00:00

  • A case of tuberculous pericardial effusion.

    abstract::Tuberculosis accounts for up to 4% of acute pericarditis and 7% cases of cardiac tamponade. Prompt treatment can be life saving but requires accurate diagnosis. We report a case of 30-year-old male who presented with fever, chills, and dry nonproductive cough since one month. The case was diagnosed by radiological fin...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Wanjari K,Baradkar V,Mathur M,Kumar S

    更新日期:2009-01-01 00:00:00

  • Trends in antimicrobial susceptibility of Salmonella Typhi from North India (2001-2012).

    abstract:PURPOSE:Enteric fever is endemic in India with Salmonella Typhi being the major causative agent. Antibiotic therapy constitutes the mainstay of management. The present study was undertaken to find the susceptibility profile of Salmonella enterica var Typhi (S. Typhi) blood isolates in a tertiary care hospital between J...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.129799

    authors: Singhal L,Gupta PK,Kale P,Gautam V,Ray P

    更新日期:2014-04-01 00:00:00

  • Effectiveness of hand hygiene promotional program based on the WHO multimodal hand hygiene improvement strategy, in terms of compliance and decontamination efficacy in an indian tertiary level neonatal surgical intensive care unit.

    abstract:Background:The WHO Multimodal Hand Hygiene Improvement Strategy (MHHIS) has been proposed to improve the Hand Hygiene (HH) compliance of the WHO recommendations on HH.Therefore, the current study was planned in our neonatal unit with the objective of evaluating the effectiveness of a Hand Hygiene Promotional Program (H...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_20_47

    authors: Thomas AM,Kaur S,Biswal M,N Rao KL,Vig S

    更新日期:2019-10-01 00:00:00

  • Vibrionaceae from cases of acute diarrhoea and their antimicrobial sensitivity pattern - a five year prospective study.

    abstract::Over a five year period, stool samples were screened for Vibrionaceae from cases of acute diarrhoea, to study their isolation rate and their antimicrobial sensitivity pattern. All the isolates were identified by standard laboratory techniques. A total of 323 species belonging to Vibrionaceae were isolated from 4492 st...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Mathur M,De A,Saraswathi K,Varaiya A,Athalye S

    更新日期:2003-07-01 00:00:00

  • Extended spectrum -lactamases (ESBL) - an emerging threat to clinical therapeutics.

    abstract::Extended spectrum -lactamases (ESBLs) are plasmid mediated, TEM and SHV derived enzymes, first isolated in Western Europe in mid 1980s, most commonly in Klebsiella spp., followed by Escherichia coli. These enzymes are capable of hydrolyzing broad spectrum cephalosporins and monobactams but inactive against cephamycins...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Chaudhary U,Aggarwal R

    更新日期:2004-04-01 00:00:00

  • Food poisoning due to Salmonella enterica serotype weltevreden in Mangalore.

    abstract::An outbreak of food poisoning due to Salmonella enterica serotype Weltevreden ( S.weltevreden ) involving 34 students has been reported from a tertiary care hospital in Mangalore. The symptoms developed 8-10 hours, after consuming a non- vegetarian dish, probably fish, from an outside caterer. The identity of the orga...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.53211

    authors: Antony B,Dias M,Shetty AK,Rekha B

    更新日期:2009-07-01 00:00:00

  • Detection of opportunistic DNA viral infections by multiplex PCR among HIV infected individuals receiving care at a tertiary care hospital in South India.

    abstract:PURPOSE:Opportunistic viral infections cause increased morbidity and mortality among human immunodeficiency virus (HIV) infected individuals, especially those who are not on antiretroviral treatment. Early diagnosis of these opportunistic viruses will be able to reduce the risk of disease progression with appropriate i...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.53202

    authors: Sachithanandham J,Ramamurthy M,Kannangai R,Daniel HD,Abraham OC,Rupali P,Pulimood SA,Abraham AM,Sridharan G

    更新日期:2009-07-01 00:00:00

  • Occurrence of II and V staphylococcal cassette chromosome mec types among coagulase-negative staphylococci from Northeastern part of India.

    abstract:Introduction:Coagulase Negative Staphylococci, the most commonly isolated pathogen are becoming emerging threats to the community as well as to the nosocomial environment. The present study underscores the distribution of Staphylococcal cassette chromosome mec (SCCmec) types among Methicillin resistant Coagulase Negati...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_18_285

    authors: Bhowmik D,Chakraborty P,Bhowmick R,Sarkar R,Chetri S,Bhattacharjee A

    更新日期:2018-10-01 00:00:00

  • Seroprevalence, risk factors and genotype distribution for Hepatitis C infection: A study from rural hospital in Maharashtra.

    abstract:BACKGROUND AND OBJECTIVES:Hepatitis C is global health problem affecting a significant portion of the world's population. Available data in Western Maharashtra on seroprevalence, risk factors and genotype distribution are very limited. OBJECTIVES:The present study was carried out to estimate the seroprevalence, factor...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_16_96

    authors: Patil SR,Datkhile KD,Ghorpade MV,Patil SS,Kakade SV

    更新日期:2017-10-01 00:00:00

  • First case of Paragonimus westermani infection in a female patient in India.

    abstract::Paragonimiasis is a foodborne parasitic zoonosis caused by lung fluke species of the genus Paragonimus. The Paragonimus westermani is the most common human pathogen in Asian countries. In northeast India, Paragonimus heterotremus has been documented as the only human pathogen in the earlier literature. In India, P. we...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.150950

    authors: Singh TS,Hiromu S,Devi KR,Singh WA

    更新日期:2015-02-01 00:00:00