Spiritual activation in very elderly individuals assessed as heart rate variability and plasma IL/10/IL-6 ratios.

Abstract:

:Proinflammatory cytokine responses might occur in elderly individuals with cardiovascular (CV) disease, cerebro-vascular (CVA) disease, and/or pulmonary disease (PD). Spiritual activation is an important coping mechanism, since psychiatric depression is an important risk factor for these individuals. Thirty-three very elderly individuals (87 ± 8 years) with previous CVD, CVA and/or PD participated in weekly 30 minute sermons by chaplains for over 20 months of chaplain liturgy (CL group). All underwent Holter ECG during the procedures and cardiac autonomic activities were assessed by maximum entropy analysis. Plasma IL-10 and IL-6 levels were compared with 26 age-matched (85 ± 10 years) individuals who did not participate in these activities (non-CL group). Both high frequency (HF) and pNN50 of heart rate variability (HRV) were higher in the CL group than in the non-CL group (HF, 190 ± 55 versus 92 ± 43 nu, P < 0.05; pNN50, 10.5 ± 16% versus 3.6 ± 3.8%, P < 0.05), whereas LF/HF was lower (1.4 ± 1.5 versus 2.2 ± 2.8, P < 0.05). Levels of IL-10/IL-6 were higher in the CL group (3.96 ± 5.0 versus 1.79 ± 1.6, P < 0.05). Hospitalization rates due to CVD and/or PD were lower in the CL group than in the non-CL group (4/33 versus 11/26, P < 0.05). We conclude that spiritual activation can modify proinflammatory cytokines and suppress CVD, CVA and/or PD via vagal modifications. Spiritual activation might be helpful for health in these very elderly individuals.

journal_name

Int Heart J

authors

Kurita A,Takase B,Shinagawa N,Kodani E,Okada K,Iwahara S,Kusama Y,Atarashi H

doi

10.1536/ihj.52.299

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

299-303

issue

5

eissn

1349-2365

issn

1349-3299

pii

JST.JSTAGE/ihj/52.299

journal_volume

52

pub_type

杂志文章
  • Effect of balance training on walking speed and cardiac events in elderly patients with ischemic heart disease.

    abstract::The purpose of this study was to clarify the effect of standing balance training on walking speed (short-term outcome) and cardiac events (long-term outcome) in elderly ischemic heart disease (IHD) patients. This was a retrospective cohort study. Ninety-two elderly (≥ 65 years) IHD patients who underwent an inpatient ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.14-017

    authors: Yamamoto S,Matsunaga A,Wang G,Hoshi K,Kamiya K,Noda C,Kimura M,Yamaoka-Tojo M,Masuda T

    更新日期:2014-01-01 00:00:00

  • Sex Differences in Clinical Characteristics and 2-Year Prognosis of Patients with Heart Failure Grouped by Left Ventricular Ejection Fraction Status.

    abstract::After the new left ventricular ejection fraction (LVEF) classification criteria emerged, many studies have focused on the differences between heart failure (HF) with reduced EF (HFrEF), HF with midrange EF (HFmrEF), and HF with preserved EF (HFpEF). However, the lack of consensus on sex-related differences in prognosi...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.20-321

    authors: Wang C,Zhou Y,Zhong R,Bao Y,Li Z,Tian J

    更新日期:2020-11-28 00:00:00

  • Low Consultation Rate of General Population with Atrial Fibrillation.

    abstract::In order to prevent ischemic stroke, it is important to identify and treat patients with atrial fibrillation (AF) who do not consult a doctor in a medical institution. The aim of this study was to determine the consultation rate at medical institutions for patients with AF in group medical examinations conducted in a ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.19-062

    authors: Matsumi H,Nakamura K,Eguchi E,Miyoshi T,Nakagawa K,Nishii N,Watanabe A,Ueoka A,Yoshida M,Tokunaga N,Amioka N,Yamada N,Saito D,Morita H,Ogino K,Ito H,Ibara-AF Investigators.

    更新日期:2019-11-30 00:00:00

  • A case of marked diuresis by combined dopamine and atrial natriuretic peptide administration without renal injury in acute decompensated heart failure.

    abstract::Renal injury is an important factor for worsening outcome in acute decompensated heart failure (ADHF). An 81-year-old woman was admitted due to ADHF with dyspnea and mild peripheral edema. The patient was managed with intravenous administration of atrial natriuretic peptide (ANP) at a dose of 0.0125 μg/kg/minute, whic...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.54.243

    authors: Kamiya M,Sato N,Akiya M,Okazaki H,Takahashi Y,Mizuno K

    更新日期:2013-01-01 00:00:00

  • Lack of association between low HDL-cholesterol and elevated circulating cellular adhesion molecules in normolipidemic CAD patients and healthy subjects.

    abstract::High plasma HDL-cholesterol (HDL-c) is a well-established protective factor in coronary artery disease (CAD). One of its potential protective mechanisms is the inhibition of the cytokine-induced upregulation of expression of cellular adhesion molecules (CAMs). High sCAM levels were found to be associated with low HDL-...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.46.593

    authors: Stanojević NB,Ivanović ZJ,Djurovic S,Kalimanovska VS,Spasić S,Ostrić DK,Memon L

    更新日期:2005-07-01 00:00:00

  • Paracorporeal Ventricular Assist Device Implantation in a Patient with Transposition of the Great Arteries After Senning Operation.

    abstract::We experienced a 33-year-old patient with D-looped transposition of the great arteries (D-TGA) and a history of Senning operation who was referred to our institute with cardiogenic shock and subsequently underwent urgent paracorporeal ventricular assist device (VAD) implantation, which was a first in Japan, that was e...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.19-670

    authors: Nakamura M,Imamura T,Kuwahara H,Nakagaito M,Yokoyama S,Doi T,Fukahara K,Yoshimura N,Kinugawa K

    更新日期:2020-05-30 00:00:00

  • Efficacy of intrathoracic impedance and remote monitoring in patients with an implantable device after the 2011 great East Japan earthquake.

    abstract::Several studies have revealed that stress after catastrophic disasters can trigger cardiovascular events, however, little is known about its association with the occurrence of heart failure in past earthquakes. The objective of the present study was to determine whether the Great East Japan Earthquake on March 11, 201...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.13-215

    authors: Suzuki H,Yamada S,Kamiyama Y,Takeishi Y

    更新日期:2014-01-01 00:00:00

  • Relation of Systolic Blood Pressure on the Following Day with Post-Discharge Mortality in Hospitalized Heart Failure Patients with Preserved Ejection Fraction.

    abstract::The clinical scenario, which is based on systolic blood pressure (SBP) upon admission, is useful for classifying and determining initial treatment for acute heart failure (HF). However, the prognostic significance of SBP following the initial treatment is unclear.The Japanese Heart Failure Syndrome with Preserved Ejec...

    journal_title:International heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1536/ihj.18-699

    authors: Sato Y,Yoshihisa A,Oikawa M,Nagai T,Yoshikawa T,Saito Y,Yamamoto K,Takeishi Y,Anzai T

    更新日期:2019-07-27 00:00:00

  • Exogenous Hydrogen Sulfide Postconditioning Protects Isolated Rat Hearts From Ischemia/Reperfusion Injury Through Sirt1/PGC-1α Signaling Pathway.

    abstract::Sirt1 is a highly conserved nicotinamide adenine dinucleotide (NAD(+)) dependent histone deacetylase which plays an important role in heart diseases. Studies performed with Sirt1 activators indicated that it protects cells from ischemia/ reperfusion (I/R) injury. The protective effects of H2S against I/R injury also h...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.15-506

    authors: Hu MZ,Zhou B,Mao HY,Sheng Q,Du B,Chen JL,Pang QF,Ji Y

    更新日期:2016-07-27 00:00:00

  • Plasma Levels of Receptor for Advanced Glycation End-Products and High-Mobility Group Box 1 in Patients With Pulmonary Hypertension.

    abstract::An increase of pulmonary artery pressure in patients with pulmonary hypertension (PH) results in right ventricular failure and ultimately death. High-mobility group box 1 (HMGB1), a nuclear protein, acts as a pro-inflammatory cytokine by activating receptor for advanced glycation end-products (RAGE) in the extracellul...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.15-188

    authors: Suzuki S,Nakazato K,Sugimoto K,Yoshihisa A,Yamaki T,Kunii H,Suzuki H,Saitoh S,Takeishi Y

    更新日期:2016-01-01 00:00:00

  • High Levels of Circulating MicroRNA-3667-3p Are Associated with Coronary Plaque Erosion in Patients with ST-Segment Elevation Myocardial Infarction.

    abstract::Plaque erosion (PE) is a significant substrate of acute coronary thrombosis. An improved ability to distinguish plaque phenotype in vivo among patients with ST-segment elevation myocardial infarction (STEMI) is of considerable interest because of the potential to formulate tailored treatment. This study assessed the p...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.19-014

    authors: Dong H,Hu S,Sun R,Wang C,Dai J,Pan W,Xing L,Liu X,Wu J,Liu J,Jia H,Yu B

    更新日期:2019-09-27 00:00:00

  • Involvement of Apelin/APJ Axis in Thrombogenesis in Valve Heart Disease Patients with Atrial Fibrillation.

    abstract::The mechanism underlying thrombosis in atrial fibrillation (AF) is not yet clearly understood. The apelin/APJ axis parallel and counter-regulate with the angiotensin system. The present study hypothesizes that apelin/APJ axis exert its anti-thrombus effect in normal left atrial tissue and is disrupted by up-regulated ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.18-166

    authors: Cheng H,Chen Y,Li X,Chen F,Zhao J,Hu J,Shan A,Qiao S,Wei Z,He G,Xu B

    更新日期:2019-01-25 00:00:00

  • Deeper S Wave in Lead V5 and Broader Extent of T Wave Inversions in the Precordial Leads are Clinically Useful Electrocardiographic Parameters for Predicting Pulmonary Hypertension.

    abstract::Electrocardiography (ECG) is used to screen for pulmonary hypertension (PH). However, it is unclear which parameters of ECG are the most useful for screening.ECG parameters related to right ventricular hypertrophy criteria were examined in 145 ECGs of subjects who were suspected to have PH and underwent right heart ca...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.16-647

    authors: Miura M,Ikeda S,Yoshida T,Yamagata Y,Nakata T,Koga S,Koide Y,Kawano H,Maemura K

    更新日期:2018-01-27 00:00:00

  • Clinical Characteristics and Long-Term Outcomes of Hypertrophic Cardiomyopathy.

    abstract::Hypertrophic cardiomyopathy (HCM) has various morphological and clinical features. A decade has passed since the previous survey of the epidemiological and clinical characteristics of Japanese HCM patients. The Aichi Hypertrophic Cardiomyopathy (AHC) Registry is based on a prospective multicenter observational study o...

    journal_title:International heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1536/ihj.14-418

    authors: Yoshinaga M,Yoshikawa D,Ishii H,Hirashiki A,Okumura T,Kubota A,Sakai S,Harada K,Somura F,Mizuno T,Fujiwara W,Yokoi H,Hayashi M,Ishii J,Ozaki Y,Murohara T,Yoshida Y,Amano T,Izawa H

    更新日期:2015-01-01 00:00:00

  • Rivaroxaban for Periprocedural Anticoagulation Therapy in Japanese Patients Undergoing Catheter Ablation of Paroxysmal Non-Valvular Atrial Fibrillation.

    abstract::Direct oral anticoagulants (DOACs) have been shown to be safe and effective for the prevention of stroke in nonvalvular atrial fibrillation (NVAF) patients, however, experience with peri-AF ablation management of DOACs is scarce. This study aimed to investigate the safety and feasibility of periprocedural anticoagulat...

    journal_title:International heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1536/ihj.16-147

    authors: Kawabata M,Sasaki T,Maeda S,Shirai Y,Yamauchi Y,Nitta J,Goya M,Hirao K

    更新日期:2016-12-02 00:00:00

  • Cardiac Sarcoidosis Mimicking Septal Tumor with Intermittent Complete Atrioventricular Block.

    abstract::A 52-year-old woman with intermittent complete atrioventricular (AV) block detected on exercise was admitted to the hospital. Echocardiography revealed lesions on the right ventricular side of the interventricular septum and free wall of the basal inferolateral area. Gadolinium-enhanced cardiovascular magnetic resonan...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.17-713

    authors: Fujimoto R,Asano T,Maezawa H,Shimojima H,Tsujiuchi M,Hori Y,Ebato M,Suzuki H

    更新日期:2018-11-28 00:00:00

  • Destructive Role of TMAO in T-Tubule and Excitation-Contraction Coupling in the Adult Cardiomyocytes.

    abstract::Heart failure (HF) is a disease with high morbidity and mortality. In patients with HF, decreased cardiac output and blood redistribution results in decreased intestinal perfusion and destruction of intestinal barrier. Microorganisms and endotoxins can migrate into the blood circulation, aggravating systemic inflammat...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.19-372

    authors: Jin B,Ji F,Zuo A,Liu H,Qi L,He Y,Wang Q,Zhao P

    更新日期:2020-03-28 00:00:00

  • Successful Infant Pneumonectomy with Unilateral Pulmonary Artery Occlusion Test.

    abstract::The use of unilateral pulmonary artery occlusion (UPAO) test for the preoperative evaluation of pneumonectomy was reported in adult patients. On the contrary, in infants, no strategies have yet been recommended to predict hemodynamics after pneumonectomy, nor has use of the UPAO test been reported. We describe the fir...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.16-606

    authors: Kato K,Kato T,Hayano S,Fukasawa Y,Numaguchi A,Hattori T,Saito A,Sato Y,Hayakawa M

    更新日期:2018-01-27 00:00:00

  • Correlation Between Arteriosclerosis and Periodontal Condition Assessed by Lactoferrin and α1-Antitrypsin Levels in Gingival Crevicular Fluid.

    abstract::Patients with periodontal disease exhibit exacerbated atherosclerosis, aortic stiffness, or vascular endothelial dysfunction. However, in a recent scientific statement, the American Heart Association noted that neither has periodontal disease been proven to cause atherosclerotic vascular disease nor has the treatment ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.15-218

    authors: Hayashi S,Yamada H,Fukui M,Ito HO,Sata M

    更新日期:2015-01-01 00:00:00

  • Diagnostic Accuracy of Three Different Protocols for 3.0T Coronary Magnetic Resonance Angiography.

    abstract::The usefulness of coronary magnetic resonance angiography (cMRA) has been reported, although the difference in the diagnostic accuracy of different protocols has not been established.We compared conventional coronary angiography (CAG) and cMRA, conducted within 6 months in 24 consecutive patients between September 201...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.15-436

    authors: Namba Y,Fuke S,Kashihara Y,Tanaka M,Yumoto A,Saito H,Sato T

    更新日期:2016-09-28 00:00:00

  • Mechanism of pressure-overload right ventricular hypertrophy in infant rabbits.

    abstract::Although pressure-overload right ventricular hypertrophy is a long-term risk in some congenital heart diseases such as tetralogy of Fallot, how it develops is unclear. The aim of this study was to investigate the mechanism of development of this right ventricular heart failure.Pulmonary artery banding in 10-day-old ra...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.52.56

    authors: Minegishi S,Kitahori K,Murakami A,Ono M

    更新日期:2011-01-01 00:00:00

  • Candidacy for a Subcutaneous Implantable Cardioverter Defibrillator in Patients with Cardiac Resynchronization Therapy.

    abstract::In patients requiring an implantable cardioverter defibrillator (ICD), the combined use of a prior pacemaker and a subcutaneous ICD (S-ICD) could be an alternative treatment option to implantation of new leads or upgrading of pacemakers to an ICD if vascular access is limited. Here, we assessed the prevalence of S-ICD...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.17-550

    authors: Kawabata M,Goya M,Takahashi Y,Maeda S,Yagishita A,Shirai Y,Kaneko M,Shiohira S,Hirao K

    更新日期:2018-09-26 00:00:00

  • Renoprotective effect of vasopressin v2 receptor antagonist tolvaptan in Dahl rats with end-stage heart failure.

    abstract::Tolvaptan is a highly selective and orally effective arginine vasopressin V2 receptor antagonist, and is potentially useful for the treatment of heart failure (HF) patients. However, the renoprotective effect of long-term tolvaptan therapy and its underlying mechanisms remain unknown. We evaluated the effects of chron...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.54.98

    authors: Ishikawa M,Kobayashi N,Sugiyama F,Onoda S,Ishimitsu T

    更新日期:2013-01-01 00:00:00

  • Experiences With Aggressive Cardiac Rehabilitation in Pediatric Patients Receiving Mechanical Circulatory Supports.

    abstract::Although some patients with fulminant myocarditis can be rescued owing to the improvements in mechanical circulatory support therapy, there are few reports providing evidence of cardiac rehabilitation during mechanical circulatory supports, particularly among pediatric patients. We treated two pediatric patients who u...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.16-067

    authors: Amao R,Imamura T,Sawada Y,Endo S,Ozaki S,Okamura K,Masuzawa A,Takaoka T,Hirata Y,Shindo T,Ono M,Haga N

    更新日期:2016-12-02 00:00:00

  • Improvements in Augmentation Index and Urinary Albumin Excretion With Benidipine in Hypertensive Patients With Chronic Kidney Disease.

    abstract::Although calcium channel blockers (CCB) are expected to improve the augmentation index (AI) in CKD patients, the potential effect of benidipine on AI has been poorly studied.The present study aimed to compare the effect of benidipine and amlodipine in the treatment of CKD patients as measured through AI and urinary al...

    journal_title:International heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1536/ihj.15-208

    authors: Takayama T,Yoda S,Yajima Y,Kasamaki Y,Kunimoto S,Kanai T,Hirayama A

    更新日期:2016-01-01 00:00:00

  • Basic echocardiographic features of patients with latent left ventricular outflow tract obstruction without left ventricular hypertrophy.

    abstract::Left ventricular outflow tract obstruction (LVOTO) is commonly observed in patients with hypertrophic cardiomyopathy (HCM) or left ventricular hypertrophy (LVH). While some patients develop LVOTO at rest, it can also be provoked by physical exertion, and hence termed latent LVOTO (L-LVOTO). Recent reports demonstrated...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.53.230

    authors: Semba H,Sawada H,Uejima T,Takeda N,Soma K,Abe H,Yamashita T,Nagai R

    更新日期:2012-01-01 00:00:00

  • Revascularization of malignant coronary instent restenosis resulting from Takayasu's arteritis using sirolimus-eluting stents.

    abstract::A 37 year-old female who had suffered from arteritis for 20 years underwent a Bentall operation. Since severe stenosis was observed in her left main coronary artery (LMCA) the following year, a minimally invasive direct coronary artery bypass (MIDCAB) operation was performed. Unfortunately, she again complained of ang...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.47.795

    authors: Sakai H,Oyama N,Kishimoto N,Takahashi M,Urasawa K,Tsutsui H

    更新日期:2006-09-01 00:00:00

  • Electrical stimulation of skeletal muscles. An alternative to aerobic exercise training in patients with chronic heart failure?

    abstract::The aim of this study was to investigate whether electrical stimulation of skeletal muscles could represent a rehabilitation alternative for patients with chronic heart failure (CHF). Thirty patients with CHF and NYHA class II-III were randomly assigned to a rehabilitation program using either electrical stimulation o...

    journal_title:International heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1536/ihj.47.441

    authors: Dobsák P,Nováková M,Fiser B,Siegelová J,Balcárková P,Spinarová L,Vítovec J,Minami N,Nagasaka M,Kohzuki M,Yambe T,Imachi K,Nitta S,Eicher JC,Wolf JE

    更新日期:2006-05-01 00:00:00

  • Native Myocardial T1 Mapping, Are We There Yet?

    abstract::T1 or longitudinal relaxation time is one of the very fundamental magnetic resonance imaging (MRI) time constants and a tissue characterizing parameter. Only during the last decade did it become possible to quantify T1 values of the myocardium through T1 mapping. Evolving from only region of interest analysis and long...

    journal_title:International heart journal

    pub_type: 杂志文章,评审

    doi:10.1536/ihj.16-169

    authors: Hamdy A,Kitagawa K,Ishida M,Sakuma H

    更新日期:2016-07-27 00:00:00

  • Association of Dyslipidemia and Sex With Coronary Artery Calcium Assessed by Coronary Computed Tomography Angiography.

    abstract::Previous studies reporting that statin increases coronary artery calcium (CAC) were conducted exclusively on patients with statin as a prevention, regardless of the presence or absence of dyslipidemia. The impact of sex on CAC has not been fully evaluated. We aimed to determine the association of dyslipidemia and sex ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.16-481

    authors: Asami M,Yamaji K,Aoki J,Tanimoto S,Watanabe M,Horiuchi Y,Furui K,Kato N,Hara K,Tanabe K

    更新日期:2017-10-21 00:00:00