Acute effect of sildenafil is maintained in pulmonary arterial hypertension patients chronically treated with bosentan.

abstract：:To investigate the combination of high-sensitivity C-reactive protein (hs-CRP) and Low-density lipoprotein (LDL)-C as the targets for statin treatment in patients with acute coronary syndrome (ACS). This single-center, prospective, randomized study was performed in 400 patients treated with atorvastatin 40 mg/day for ...

journal_title：International heart journal

authors： Fang M,Qian Q,Zhao Z,Zhu L,Su J,Li X

更新日期：2018-03-30 00:00:00

abstract：:Vaccines are commonly used as a preventive medicine for infectious diseases worldwide, however, clinical trials on an amyloid beta vaccine for Alzheimer's disease represents a new concept in the field of vaccinations. Several recent studies indicate the potential of therapeutic vaccines as well as classical vaccines a...

journal_title：International heart journal

authors： Nakagami H,Koriyama H,Morishita R

更新日期：2014-01-01 00:00:00

abstract：:We report the case of a 79-year-old man with acute myocardial infarction caused by left main trunk lesion, who experienced cardiogenic shock during percutaneous coronary intervention (PCI). To reverse the cardiogenic shock, we initiated veno-arterial extra corporeal membrane oxygenation (VA-ECMO) without an intra-aort...

journal_title：International heart journal

authors： Kaneko D,Takahashi M,Fukutomi M,Funayama H,Kario K

更新日期：2019-09-27 00:00:00

abstract：:The mechanism underlying thrombosis in atrial fibrillation (AF) is not yet clearly understood. The apelin/APJ axis parallel and counter-regulate with the angiotensin system. The present study hypothesizes that apelin/APJ axis exert its anti-thrombus effect in normal left atrial tissue and is disrupted by up-regulated ...

journal_title：International heart journal

authors： Cheng H,Chen Y,Li X,Chen F,Zhao J,Hu J,Shan A,Qiao S,Wei Z,He G,Xu B

更新日期：2019-01-25 00:00:00

abstract：:The aim of the present study was to determine if there is any association between white coat hypertension (WCH) and body mass index. The study was performed in two phases. In the first phase, we studied consecutive underweight patients, while in the second phase, age-matched consecutive normal weight, overweight, and ...

journal_title：International heart journal

authors： Helvaci MR,Kaya H,Yalcin A,Kuvandik G

更新日期：2007-09-01 00:00:00

abstract：:We experienced a 33-year-old patient with D-looped transposition of the great arteries (D-TGA) and a history of Senning operation who was referred to our institute with cardiogenic shock and subsequently underwent urgent paracorporeal ventricular assist device (VAD) implantation, which was a first in Japan, that was e...

journal_title：International heart journal

authors： Nakamura M,Imamura T,Kuwahara H,Nakagaito M,Yokoyama S,Doi T,Fukahara K,Yoshimura N,Kinugawa K

更新日期：2020-05-30 00:00:00

abstract：:This study aimed to evaluate the clinical characteristics and surgical treatment of bicuspid aortic valve (BAV) infective endocarditis (IE) compared with tricuspid aortic valve (TAV) IE in China.The relevant pre-, intra- and post-operative materials of all IE patients undergoing cardiac surgery in our center between J...

journal_title：International heart journal

authors： Chen J,Lu S,Hu K,Yang Z,Pan S,Hong T,Wang C

更新日期：2017-04-06 00:00:00

abstract：:Comparison of the prognostic value of red cell distribution width (RDW) and N-terminal pro B-type natriuretic peptide (NT-proBNP) for short-term clinical outcomes in acute heart failure (AHF) patients has not been fully investigated.A total of 128 patients with AHF were enrolled and followed for 3 months. Primary endp...

journal_title：International heart journal

authors： He W,Jia J,Chen J,Qin S,Tao H,Kong Q,Xue Q,Zhang D

更新日期：2014-01-01 00:00:00

abstract：:Several recent studies have suggested that arterial stiffness parameters such as peripheral pulse pressure (PPP), central blood pressure (CBP), and pulse wave velocity (PWV) are more accurate markers than brachial blood pressure for prediction of cardiovascular (CV) events. However, it remains unknown which arterial s...

journal_title：International heart journal

authors： Ishisone T,Koeda Y,Tanaka F,Sato K,Nagano M,Nakamura M

更新日期：2013-01-01 00:00:00

abstract：:Myocardial infarction (MI) is one of the major causes of death worldwide, and the therapeutic strategies of MI are still limited. In this study, we investigated the function of miR-665 in MI. In the present study, an ischemia/reperfusion (I/R) rat model and a hypoxia/reoxygenation (H/R)-induced H9c2 cell model were su...

journal_title：International heart journal

authors： Liu C,Tang M,Zhang X,Li J,Cao G

更新日期：2020-03-28 00:00:00

abstract：:The significance of pulse pressure (PP) and mean blood pressure (MBP) for blood pressure (BP) control is unclear. The aim of this study was to examine the relationship between PP and MBP and BP control. We obtained home BP measurements for 117 patients aged 40-75 years with either office systolic BP (SBP) >or= 140 mmH...

journal_title：International heart journal

authors： Yoshitomi Y,Nagakura C,Miyauchi A

更新日期：2005-07-01 00:00:00

abstract：:We present a 16-year-old male patient with hypoplastic left heart syndrome who developed protein-losing enteropathy (PLE) and plastic bronchitis (PB) after a Fontan operation. He received medical therapies, including albumin infusion, unfractionated heparin, and high-dose anti-aldosterone therapy but could not obtain ...

journal_title：International heart journal

authors： Okada S,Muneuchi J,Nagatomo Y,Nonaka K,Iida C,Shirouzu H,Matsuoka R,Watanabe M,Joo K

更新日期：2018-07-31 00:00:00

abstract：:Bleeding complications following percutaneous coronary interventions (PCI) have been closely associated with morbidity and mortality. Although radial arteries have been widely used in current PCI, including primary PCI, transfemoral PCI remains necessary for complex PCI. The purpose of this study was to compare the in...

journal_title：International heart journal

authors： Yamamoto S,Sakakura K,Taniguchi Y,Yamamoto K,Wada H,Momomura SI,Fujita H

更新日期：2018-05-30 00:00:00

abstract：:A 61-year-old man with prior anteroseptal myocardial infarction (ejection fraction: 40%) presented with recurrent episodes of palpitations. Twelve-lead ECG during palpitations showed an incessant ventricular tachycardia (VT1) with right bundle branch block (RBBB) morphology and inferior axis. Electrophysiologic study ...

journal_title：International heart journal

authors： Ashino S,Watanabe I,Kofune M,Okumura Y,Kawauchi K,Yamada T,Okubo K,Hashimoto K,Shindo A,Sugimura H,Nakai T,Saito S,Hirayama A

更新日期：2008-01-01 00:00:00

abstract：:Our previous study showed that pravastatin prevents ischemia and reperfusion-induced lethal ventricular fibrillation in rats. This study explored whether pravastatin decreases myocardial infarct size and this effect is associated with endothelial nitric oxide synthase (eNOS) expression in myocardium. Rats were treated...

journal_title：International heart journal

authors： Li H,Wang C,Sun J,Liu C,Li N,Chen J

更新日期：2018-01-01 00:00:00

abstract：:Mechanical heart valve replacement (MHVR) entails lifetime oral anticoagulation to eliminate thrombosis. However, adverse events may still occur despite proper anticoagulation therapy. In this study, we investigated whether D-dimer can predict the clinical events in post-MHVR patients during oral anticoagulation thera...

journal_title：International heart journal

authors： Zhang L,Long Y,Xiao H,Yang J,Liu X,Zhang Z

更新日期：2019-05-30 00:00:00

abstract：:Five patients who had had previous cardiac operations underwent minimally invasive beating heart mitral valve operations via a right minithoracotomy between November 2006 and February 2009. The mean age was 64 ± 10 years and 4 were female. Under general anesthesia with single-lumen ventilation, cardiopulmonary bypass ...

journal_title：International heart journal

authors： Kitamura T,Stuklis RG,Edwards J

更新日期：2011-01-01 00:00:00

abstract：:There have been very few studies on serum biomarkers associated with hypertension in disaster situations. We assessed biomarkers associated with disaster-related hypertension (DRH) due to the Great East Japan Earthquake of March 2011.We collected blood samples from members of the Japan Self Defense Forces (JSDF) (n = ...

journal_title：International heart journal

authors： Shiraishi Y,Kujiraoka T,Hakuno D,Masaki N,Tokuno S,Adachi T

更新日期：2016-01-01 00:00:00

abstract：:The metabolism of branched-chain amino acids (BCAAs) is reported to change in heart failure (HF) and correlate with cardiac function. However, the effect of BCAAs on HF remains controversial. We investigate the prognostic value of the plasma BCAA level in nonischemic dilated cardiomyopathy (NIDCM).This study enrolled ...

journal_title：International heart journal

authors： Kimura Y,Okumura T,Kazama S,Shibata N,Oishi H,Arao Y,Kuwayama T,Kato H,Yamaguchi S,Hiraiwa H,Kondo T,Morimoto R,Murohara T

更新日期：2020-07-30 00:00:00

abstract：:Acute aortic dissection (AAD) is a life-threatening cardiovascular disease with high mortality. Hypertension is a well known risk factor of AAD. There have been previous reports about the association between circadian variation of blood pressure (BP) and cardiovascular events. However, little is known about the associ...

journal_title：International heart journal

authors： Seguchi M,Wada H,Sakakura K,Nakagawa T,Ibe T,Ikeda N,Sugawara Y,Ako J,Momomura S

更新日期：2015-05-13 00:00:00

abstract：:Myocardial infarction (MI) occurs when the heart muscle is severely damaged due to a decrease in blood flow from the coronary arteries. During recovery from an MI, cardiac fibroblasts become activated and produce extracellular matrices, contributing to the wound healing process in the damaged heart. Inappropriate acti...

journal_title：International heart journal

authors： Wake M,Takeda N,Isagawa T,Sato T,Nakagama Y,Morioka MS,Hirota Y,Asagiri M,Maemura K,Manabe I,Tanabe K,Komuro I

更新日期：2019-07-27 00:00:00

abstract：:This study tested the therapeutic impact of double-loading dose (i.e., 600 mg) versus standard-loading dose (i.e., 300 mg) of clopidogrel on ST-segment-elevation-myocardial-infarction (STEMI) patients undergoing primary-coronary-intervention (PCI).Between January 2005 and December 2013, a total of 1461 STEMI patients ...

journal_title：International heart journal

authors： Tong MS,Sung PH,Liu CF,Chen KH,Chung SY,Chua S,Chen CJ,Lee WC,Chai HT,Yip HK,Chang HW

更新日期：2017-10-21 00:00:00

abstract：:The aims of this study were to quantify the geometrical differences in left ventricular (LV) dyssynchrony in patients with heart failure (HF) using cine-tagged MRI, and to investigate the relationship between dyssynchrony and major adverse cardiac events (MACE) in HF.In 67 patients with HF [mean LV ejection fraction (...

journal_title：International heart journal

authors： Nagao M,Yamasaki Y,Yonezawa M,Kamitani T,Kawanami S,Mukai Y,Higo T,Yabuuchi H,Sunagawa K,Honda H

更新日期：2014-01-01 00:00:00

abstract：:Transradial percutaneous coronary intervention (PCI), which is less invasive than transfemoral PCI, may facilitate early rehabilitation of patients with acute myocardial infarction (AMI). The aim of our study was to investigate whether transradial PCI is associated with a shorter coronary care unit (CCU) stay in very ...

journal_title：International heart journal

authors： Jinnouchi H,Sakakura K,Wada H,Kubo N,Sugawara Y,Nakamura T,Funayama H,Ako J,Momomura S

更新日期：2012-01-01 00:00:00

abstract：:Intraaortic balloon pumping (IABP) is a useful therapy for refractory heart failure. However, the safe duration of this therapy and possible complications due to long-term IABP support remain unclear. In this study, we reviewed retrospectively patients requiring the long-term use of IABP, defined here as 10 days or mo...

journal_title：International heart journal

authors： Oshima K,Morishita Y,Hinohara H,Kadoi Y,Hayashi Y,Tajima Y,Kunimoto F

更新日期：2005-11-01 00:00:00

abstract：:Percutaneous balloon mitral valvoplasty (PBMV) has become the treatment of choice for severe pliable rheumatic mitral stenosis. The multi-track system is a recent variation of the double-balloon technique and is easier owing to the use of a monorail balloon and a simple, single-guidewire approach. In the present study...

journal_title：International heart journal

authors： Sakr SA,Ramadan MM,Osama M

更新日期：2013-01-01 00:00:00

abstract：:Exhaled acetone concentration is one of the expected compounds to be a breath biomarker in heart failure. However, it has not been clarified how exhaled acetone concentration changes in clinical course of heart failure.To investigate whether exhaled acetone concentration changes after treatment in acute decompensated ...

journal_title：International heart journal

authors： Yokokawa T,Sato T,Suzuki S,Oikawa M,Yoshihisa A,Kobayashi A,Yamaki T,Kunii H,Nakazato K,Suzuki H,Saitoh SI,Ishida T,Shimouchi A,Takeishi Y

更新日期：2018-07-31 00:00:00

abstract：:The aim of this study was to conduct a longitudinal follow-up on age-related changes in 24-hour total heart beats (THBs) and total premature beats and their correlations in healthy elderly subjects. In 15 healthy elderly subjects (mean age, 70.0 +/- 4.1, age range at 1st recording, 64 to 80 years, 10 females, 5 males)...

journal_title：International heart journal

authors： Tasaki H,Serita T,Ueyama C,Kitano K,Seto S,Yano K,Camm AJ

更新日期：2006-07-01 00:00:00

abstract：:Changes in the expression levels of several genes have been described in aortic aneurysm specimens, however, the spectrum of diverse molecular alterations remains to be elucidated. We attempted to identify key molecules that modulate the pathogenesis of aortic aneurysm, using a complimentary DNA microarray carrying ap...

journal_title：International heart journal

authors： Taketani T,Imai Y,Morota T,Maemura K,Morita H,Hayashi D,Yamazaki T,Nagai R,Takamoto S

更新日期：2005-03-01 00:00:00

abstract：:Medical treatment for asymptomatic carotid artery stenosis (ACAS) has advanced recently. The outcomes of medical treatment and surgical treatment were evaluated to clarify the optimal treatment for ACAS.Patients with ACAS of ≥ 50% luminal narrowing underwent serial follow-up carotid artery ultrasonography for one year...

journal_title：International heart journal

authors： Sato K,Fujiyoshi K,Hoshi K,Noda C,Yamaoka-Tojo M,Ako J,Kumabe T

更新日期：2016-01-01 00:00:00