Long-term exercise-training improves QT dispersion in the metabolic syndrome.

Abstract:

:Increased QT dispersion (QTd) is a marker of myocardial electrical instability and predicts ventricular arrhythmias and sudden cardiac death. Exercise training (ET) has been shown to reduce both QTd and cardiovascular mortality in various populations. Patients with metabolic syndrome (MS) have been shown to have increased QTd. The effect of ET on QTd in MS patients however is unknown. We sought to assess the effect of a long-term (> or = 6 months) ET program on QTd parameters in MS patients with and without coronary heart disease (CHD). Fifteen CHD and 31 non-CHD patients with MS (mean age, 64 +/- 7 and 57 +/- 9 years, respectively) were identified at entry into identical ET programs. MS was defined using modified National Cholesterol Education Program criteria. A control group consisted of 8 MS patients with CHD (mean age, 65 +/- 6 years). Ventricular repolarization (QT dispersion = QTd, standard deviation of QT = SDQT, relative dispersion of QT = RDQT, QT corrected dispersion = QTcd), metabolic and exercise parameters were measured before and after ET. Program duration was over 9 months (312 +/- 100 versus 284 +/- 101 days in CHD and non-CHD cohorts, P = NS). QTd decreased in both ET groups (QTd pre versus post = 66 versus 56 ms in CHD group, P < 0.01; 58 versus 51 ms in non-CHD group, P < or = 0.01). Other ventricular repolarization parameters also improved significantly in both MS groups following ET, but remained unchanged in the control group. A long-term ET program improves QTd in patients with MS with and without CHD.

journal_name

Int Heart J

authors

Guiraud T,Gayda M,Curnier D,Juneau M,Talajic M,Fortier A,Nigam A

doi

10.1536/ihj.51.41

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

41-6

issue

1

eissn

1349-2365

issn

1349-3299

pii

JST.JSTAGE/ihj/51.41

journal_volume

51

pub_type

杂志文章
  • Can we obtain a noninvasive and continuous estimation of cardiac output? Comparison between three noninvasive methods.

    abstract::Cardiac output (CO) is often desirable for assessing the hemodynamic condition of a patient, especially in critically ill cardiac patients. Various noninvasive methods are available for this purpose. Inert gas rebreathing (IGR) and 2D-Doppler echocardiography methods have been validated. Based on the relationship betw...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.54.395

    authors: Raissuni Z,Zores F,Henriet O,Dallest S,Roul G

    更新日期:2013-01-01 00:00:00

  • Exercise Preconditioning Protects against Acute Cardiac Injury Induced by Lipopolysaccharide Through General Control Nonderepressible 2 Kinase.

    abstract::Exercise preconditioning may protect against cardiac injury induced by lipopolysaccharide (LPS), but the mechanism is unresolved. The aim of this study is to explore whether the general control nonderepressible 2 (GCN2) kinase gene is associated with the protective effect of exercise preconditioning. Eight-week-old ma...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.19-307

    authors: Sun ZG,Lu G,Zhao LL,Zhang LZ,Li A,Jing J,Xu X

    更新日期:2020-01-31 00:00:00

  • Efficacy of catheter ablation for atrial fibrillation in patients with a permanent pacemaker for atrioventricular block.

    abstract::Catheter ablation has been established to be an effective therapy for drug-refractory paroxysmal AF and is recommended as the treatment of choice for many patients, including those with a permanent pacemaker (PM). However, the clinical efficacy of catheter ablation of paroxysmal AF in patients with a permanent PM for ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.14-099

    authors: Wu JT,Dong JZ,Wang SL,Chu YJ,Wang LX,Yang CK

    更新日期:2014-01-01 00:00:00

  • Year-long antihypertensive therapy with candesartan completely prevents development of cardiovascular organ injuries in spontaneously hypertensive rats.

    abstract::Most previous studies have examined the effects of antihypertensive drugs in hypertensive animals for only a few months, and little information has been provided as to the protective effects of lifetime antihypertensive medication against cardiovascular organ injury. In this study, spontaneously hypertensive rats (SHR...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.51.359

    authors: Ishimitsu T,Honda T,Ohno E,Furukata S,Sudo Y,Nakano N,Takahashi T,Ono H,Matsuoka H

    更新日期:2010-01-01 00:00:00

  • Single Femoral Venous Drainage Versus Both Vena Cava Drainage in Isolated Repeat Tricuspid Valve Surgery.

    abstract::To assess the potential advantages of minimally invasive surgery using a single femoral venous drainage method versus femoral venous and superior vena cava or jugular venous drainage method during repeat tricuspid valve surgery.From January 2010 to December 2016, 50 repeat tricuspid valve procedures were performed usi...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.17-169

    authors: Peng R,Shi H,Ba J,Wang C

    更新日期:2018-05-30 00:00:00

  • Sex Differences in Clinical Characteristics and 2-Year Prognosis of Patients with Heart Failure Grouped by Left Ventricular Ejection Fraction Status.

    abstract::After the new left ventricular ejection fraction (LVEF) classification criteria emerged, many studies have focused on the differences between heart failure (HF) with reduced EF (HFrEF), HF with midrange EF (HFmrEF), and HF with preserved EF (HFpEF). However, the lack of consensus on sex-related differences in prognosi...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.20-321

    authors: Wang C,Zhou Y,Zhong R,Bao Y,Li Z,Tian J

    更新日期:2020-11-28 00:00:00

  • A New Aortic Arch Inclusion Technique with Frozen Elephant Trunk for Aortic Arch Aneurysm Treatment.

    abstract::Various surgical techniques have been proposed for treating aortic arch aneurysm (AAA); however, the optimal treatment has not been well defined. This study introduces a new aortic arch inclusion technique with frozen elephant trunk (FET) for AAA treatment.A retrospective analysis was performed among 22 patients for A...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.20-069

    authors: Zhu C,Piao H,Wang Y,Li B,Zhang Y,Xu J,Wang T,Zhu Z,Xu R,Li D,Liu K

    更新日期:2020-11-28 00:00:00

  • Induction of c-fos mRNA expression by pure pressure overload in cultured cardiac myocytes.

    abstract::Mechanical stress by pressure overload due to hypertension or valvular heart disease such as aortic valve stenosis induces cardiac hypertrophy. It has been well established that the mechanical stretch of cardiac myocytes in vitro induces hypertrophic responses such as the expression of immediate early response genes i...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.48.359

    authors: Sakai H,Urasawa K,Oyama N,Kaneta S,Saito T,Kitabatake A,Tsutsui H

    更新日期:2007-05-01 00:00:00

  • A case of atrioventricular nodal reentrant tachycardia with atresia of the coronary sinus ostium.

    abstract::We report a case of atrioventricular nodal reentrant tachycardia coexistent with atresia of the coronary sinus ostium. Radiofrequency current application between the supposed coronary sinus ostium and the tricuspid valve was effective at eliminating the tachycardia. A coronary venogram obtained by left coronary arteri...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.46.899

    authors: Okuyama Y,Oka T,Mizuno H,Sakai T,Hirayama A,Kodama K

    更新日期:2005-09-01 00:00:00

  • Cell Cycle Perturbation Induces Collagen Production in Fibroblasts.

    abstract::Myocardial infarction (MI) occurs when the heart muscle is severely damaged due to a decrease in blood flow from the coronary arteries. During recovery from an MI, cardiac fibroblasts become activated and produce extracellular matrices, contributing to the wound healing process in the damaged heart. Inappropriate acti...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.18-710

    authors: Wake M,Takeda N,Isagawa T,Sato T,Nakagama Y,Morioka MS,Hirota Y,Asagiri M,Maemura K,Manabe I,Tanabe K,Komuro I

    更新日期:2019-07-27 00:00:00

  • Relation of Systolic Blood Pressure on the Following Day with Post-Discharge Mortality in Hospitalized Heart Failure Patients with Preserved Ejection Fraction.

    abstract::The clinical scenario, which is based on systolic blood pressure (SBP) upon admission, is useful for classifying and determining initial treatment for acute heart failure (HF). However, the prognostic significance of SBP following the initial treatment is unclear.The Japanese Heart Failure Syndrome with Preserved Ejec...

    journal_title:International heart journal

    pub_type: 杂志文章,多中心研究

    doi:10.1536/ihj.18-699

    authors: Sato Y,Yoshihisa A,Oikawa M,Nagai T,Yoshikawa T,Saito Y,Yamamoto K,Takeishi Y,Anzai T

    更新日期:2019-07-27 00:00:00

  • D-Dimer to Predict the Clinical Outcomes in Patients with Mechanical Heart Valve Replacement During Oral Anticoagulation Therapy.

    abstract::Mechanical heart valve replacement (MHVR) entails lifetime oral anticoagulation to eliminate thrombosis. However, adverse events may still occur despite proper anticoagulation therapy. In this study, we investigated whether D-dimer can predict the clinical events in post-MHVR patients during oral anticoagulation thera...

    journal_title:International heart journal

    pub_type: 临床试验,杂志文章

    doi:10.1536/ihj.18-237

    authors: Zhang L,Long Y,Xiao H,Yang J,Liu X,Zhang Z

    更新日期:2019-05-30 00:00:00

  • Relationship between sleep-disordered breathing level and acute onset time of congestive heart failure.

    abstract::Sleep-disordered breathing (SDB) is frequently observed in patients with congestive heart failure. Recent studies have shown that SDB negatively affects the onset of congestive heart failure; however, no studies have addressed the relationship between the level of SDB and the onset time of acute dyspnea. We hypothesiz...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.49.471

    authors: Yoneyama K,Osada N,Shimozato T,Ishibashi Y,Hayashi A,Takahashi E,Kida K,Suzuki K,Tamura M,Inoue K,Akashi YJ,Omiya K,Miyake F,Izawa KP,Watanabe S

    更新日期:2008-07-01 00:00:00

  • Assessment of transthyretin combined with mini nutritional assessment on admission provides useful prognostic information in patients with acute decompensated heart failure.

    abstract::Decreased Transthyretin (TTR) can be observed in heart failure patients with malnutrition evaluated by the Mini Nutritional Assessment (MNA). This study investigated whether a combination of different nutritional assessment methods would be useful for assessing prognosis in patients with acute decompensated heart fail...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.14-255

    authors: Suzuki N,Kida K,Suzuki K,Harada T,Akashi YJ

    更新日期:2015-01-01 00:00:00

  • Congenital solitary kidney with renovascular hypertension diagnosed by means of captopril-enhanced renography and magnetic resonance angiography.

    abstract::A 24 year-old woman had a congenital solitary kidney with renovascular hypertension due to fibromuscular dysplasia. She had been treated as having essential hypertension until she developed preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome at 28 weeks of gestation. Plasma reni...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.46.347

    authors: Hayashida M,Watanabe N,Imamura H,Kumazaki S,Kitabayashi H,Takahashi W,Uchikawa S,Yazaki Y,Kubo K

    更新日期:2005-03-01 00:00:00

  • Usefulness and Safety of a Novel Modification of the Retrograde Approach for the Long Tortuous Chronic Total Occlusion of Coronary Arteries.

    abstract::The aim of this study was to evaluate the feasibility and efficacy of the Guidezilla guide extension catheter in a reverse controlled antegrade and retrograde subintimal tracking (CART) technique for chronic total occlusion (CTO) recanalization.We retrospectively collected 80 CTO cases using reverse CART technology fr...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.16-337

    authors: Huang Z,Zhang B,Chai W,Ma D,Liao H,Zhong Z,Wang F,Lin J

    更新日期:2017-05-31 00:00:00

  • Exogenous Hydrogen Sulfide Postconditioning Protects Isolated Rat Hearts From Ischemia/Reperfusion Injury Through Sirt1/PGC-1α Signaling Pathway.

    abstract::Sirt1 is a highly conserved nicotinamide adenine dinucleotide (NAD(+)) dependent histone deacetylase which plays an important role in heart diseases. Studies performed with Sirt1 activators indicated that it protects cells from ischemia/ reperfusion (I/R) injury. The protective effects of H2S against I/R injury also h...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.15-506

    authors: Hu MZ,Zhou B,Mao HY,Sheng Q,Du B,Chen JL,Pang QF,Ji Y

    更新日期:2016-07-27 00:00:00

  • Renoprotective effect of vasopressin v2 receptor antagonist tolvaptan in Dahl rats with end-stage heart failure.

    abstract::Tolvaptan is a highly selective and orally effective arginine vasopressin V2 receptor antagonist, and is potentially useful for the treatment of heart failure (HF) patients. However, the renoprotective effect of long-term tolvaptan therapy and its underlying mechanisms remain unknown. We evaluated the effects of chron...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.54.98

    authors: Ishikawa M,Kobayashi N,Sugiyama F,Onoda S,Ishimitsu T

    更新日期:2013-01-01 00:00:00

  • Mechanism of pressure-overload right ventricular hypertrophy in infant rabbits.

    abstract::Although pressure-overload right ventricular hypertrophy is a long-term risk in some congenital heart diseases such as tetralogy of Fallot, how it develops is unclear. The aim of this study was to investigate the mechanism of development of this right ventricular heart failure.Pulmonary artery banding in 10-day-old ra...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.52.56

    authors: Minegishi S,Kitahori K,Murakami A,Ono M

    更新日期:2011-01-01 00:00:00

  • Taurine Protects Primary Neonatal Cardiomyocytes Against Apoptosis Induced by Hydrogen Peroxide.

    abstract::The aim of this study was to investigate the effects of taurine (Tau) on primary cultured neonatal myocardial cells treated with hydrogen peroxide (H2O2) and the underlying mechanism. Primary cardiac myocytes from neonatal Wistar rats were pre-incubated with Tau, and its effects on cell viability and expression of CaM...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.16-372

    authors: Wang J,Qi C,Liu L,Zhao L,Cui W,Tian Y,Liu B,Li J

    更新日期:2018-01-27 00:00:00

  • Diagnostic Accuracy of Three Different Protocols for 3.0T Coronary Magnetic Resonance Angiography.

    abstract::The usefulness of coronary magnetic resonance angiography (cMRA) has been reported, although the difference in the diagnostic accuracy of different protocols has not been established.We compared conventional coronary angiography (CAG) and cMRA, conducted within 6 months in 24 consecutive patients between September 201...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.15-436

    authors: Namba Y,Fuke S,Kashihara Y,Tanaka M,Yumoto A,Saito H,Sato T

    更新日期:2016-09-28 00:00:00

  • Errata: Polysaccharides from Enteromorpha Prolifera Ameliorate Acute Myocardial Infarction in Vitro and in Vivo via Up-Regulating HIF-1α.

    abstract::An error appeared in the article entitled "Polysaccharides from Enteromorpha Prolifera Ameliorate Acute Myocardial Infarction in Vitro and in Vivo via Up-Regulating HIF-1α" by Zongqiu Wang, Zhihua Zhang, Jing Zhao, Chunming Yong, and Yongjun Mao (Vol. 60, No. 4, 964-973, 2019).The second affiliation of the authors on ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.60-5_Erratum

    authors: Wang Z,Zhang Z,Zhao J,Yong C,Mao Y

    更新日期:2019-01-01 00:00:00

  • Effect of balance training on walking speed and cardiac events in elderly patients with ischemic heart disease.

    abstract::The purpose of this study was to clarify the effect of standing balance training on walking speed (short-term outcome) and cardiac events (long-term outcome) in elderly ischemic heart disease (IHD) patients. This was a retrospective cohort study. Ninety-two elderly (≥ 65 years) IHD patients who underwent an inpatient ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.14-017

    authors: Yamamoto S,Matsunaga A,Wang G,Hoshi K,Kamiya K,Noda C,Kimura M,Yamaoka-Tojo M,Masuda T

    更新日期:2014-01-01 00:00:00

  • Skeletal Muscle Abnormalities in Heart Failure.

    abstract::Exercise capacity is lowered in patients with heart failure, which limits their daily activities and also reduces their quality of life. Furthermore, lowered exercise capacity has been well demonstrated to be closely related to the severity and prognosis of heart failure. Skeletal muscle abnormalities including abnorm...

    journal_title:International heart journal

    pub_type: 杂志文章,评审

    doi:10.1536/ihj.15-108

    authors: Kinugawa S,Takada S,Matsushima S,Okita K,Tsutsui H

    更新日期:2015-01-01 00:00:00

  • Efficacy and safety of controlled-release isosorbide-5-mononitrate in Japanese patients with stable effort angina pectoris.

    abstract::A new controlled-release isosorbide-5-mononitrate (CR-ISMN) preparation has been developed to meet the requirement for a low nitrate concentration interval in order to avoid nitrate tolerance. We conducted a randomized, double-blind, placebo-controlled study in 31 Japanese patients with stable effort angina pectoris t...

    journal_title:International heart journal

    pub_type: 杂志文章,随机对照试验

    doi:10.1536/ihj.47.695

    authors: Shimada K,Sunayama S,Nakazato K,Satoh H,Kusama Y,Kawakubo K,Daida H

    更新日期:2006-09-01 00:00:00

  • Effects of Statins and Xuezhikang on the Expression of Secretory Phospholipase A2, Group IIA in Rat Vascular Smooth Muscle Cells.

    abstract::Atherosclerosis is a multifactorial vascular disease characterized by formation of inflammatory lesions. Secretory phospholipase A2, group IIA (sPLA2-IIA) is involved in this process and plays a critical role. However, the exact role of sPLA2-IIA in cardiovascular inflammation is more complicated and remains unclear. ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.16-163

    authors: Xie Q,Zhang D

    更新日期:2017-02-07 00:00:00

  • Efficacy of intrathoracic impedance and remote monitoring in patients with an implantable device after the 2011 great East Japan earthquake.

    abstract::Several studies have revealed that stress after catastrophic disasters can trigger cardiovascular events, however, little is known about its association with the occurrence of heart failure in past earthquakes. The objective of the present study was to determine whether the Great East Japan Earthquake on March 11, 201...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.13-215

    authors: Suzuki H,Yamada S,Kamiyama Y,Takeishi Y

    更新日期:2014-01-01 00:00:00

  • Inverse relationship between adiponectin levels and subclinical carotid atherosclerosis in patients undergoing coronary artery bypass grafting.

    abstract::The purpose of this study was to examine the relation between adiponectin levels and subclinical carotid atherosclerosis in patients undergoing coronary artery bypass grafting (CABG). Serum concentrations of adiponectin and carotid intima/media thickness (IMT) were measured in 84 consecutive patients who underwent CAB...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.47.855

    authors: Kiris I,Tekin I,Yesildag A,Vural H,Oyar O,Sirin B,Okutan H,Ibrisim E

    更新日期:2006-11-01 00:00:00

  • C-reactive protein is related to impaired oxygenation in patients with acute aortic dissection.

    abstract::Impaired oxygenation sometimes occurs in patients with acute aortic dissection, however, the mechanism has not been fully investigated. We hypothesized that impaired oxygenation is related to inflammation secondary due to aortic dissection. Patients with acute aortic dissection who had received 14 days of conservative...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.46.795

    authors: Komukai K,Shibata T,Mochizuki S

    更新日期:2005-09-01 00:00:00

  • Prevalence of white coat hypertension in underweight and overweight subjects.

    abstract::The aim of the present study was to determine if there is any association between white coat hypertension (WCH) and body mass index. The study was performed in two phases. In the first phase, we studied consecutive underweight patients, while in the second phase, age-matched consecutive normal weight, overweight, and ...

    journal_title:International heart journal

    pub_type: 杂志文章

    doi:10.1536/ihj.48.605

    authors: Helvaci MR,Kaya H,Yalcin A,Kuvandik G

    更新日期:2007-09-01 00:00:00