Abstract:
:Catheter ablation has been established to be an effective therapy for drug-refractory paroxysmal AF and is recommended as the treatment of choice for many patients, including those with a permanent pacemaker (PM). However, the clinical efficacy of catheter ablation of paroxysmal AF in patients with a permanent PM for atrioventricular block (AVB) is not clear. Twenty-nine patients with a permanent PM for AVB (AVB + PM group), and 145 age- and gender-matched control patients (on a 1:5 basis) without AVB and without a permanent PM (no-AVB + no-PM group), were included in this study. Atrial fibrillation (AF) recurrence was defined as the occurrence of confirmed atrial tachyarrhythmia lasting more than 30 seconds beyond 3 months after catheter ablation in the absence of any antiarrhythmic treatment. During a mean follow-up period of 14.2 ± 8.6 months (range, 3-30 months), 54 patients (31.0%) developed recurrence of AF. The recurrence rate was higher in the AVB + PM group than in the no-AVB + no-PM group (48.3% versus 27.6%, P = 0.005). Cox regression analysis with adjustment for age, valvular heart disease, AVB and a PM together, left atrial (LA) diameter and PV isolation identified LA diameter (hazard ratio 1.054, 95% confidence interval 1.001-1.110, P = 0.047) and AVB and a PM together (hazard ratio 2.095, 95% confidence interval 1.109-3.960, P = 0.023) as two independent predictors of recurrence of AF. Patients with a permanent PM for AVB were at an increased risk of recurrence of AF after catheter ablation.
journal_name
Int Heart Jjournal_title
International heart journalauthors
Wu JT,Dong JZ,Wang SL,Chu YJ,Wang LX,Yang CKdoi
10.1536/ihj.14-099subject
Has Abstractpub_date
2014-01-01 00:00:00pages
489-93issue
6eissn
1349-2365issn
1349-3299pii
DN/JST.JSTAGE/ihj/14-099journal_volume
55pub_type
杂志文章abstract::Hyperglycemia is an established risk factor of coronary artery disease (CAD). However, hyperglycemia with preserved pancreatic β cell function induces hyperinsulinemia to correct the glucose profile and may even result in reactive hypoglycemia (RH), which induces an inflammatory response. In this study, the incidence ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.17-245
更新日期:2018-07-31 00:00:00
abstract::Hypertrophic cardiomyopathy (HCM) has various morphological and clinical features. A decade has passed since the previous survey of the epidemiological and clinical characteristics of Japanese HCM patients. The Aichi Hypertrophic Cardiomyopathy (AHC) Registry is based on a prospective multicenter observational study o...
journal_title:International heart journal
pub_type: 杂志文章,多中心研究
doi:10.1536/ihj.14-418
更新日期:2015-01-01 00:00:00
abstract::An increase of pulmonary artery pressure in patients with pulmonary hypertension (PH) results in right ventricular failure and ultimately death. High-mobility group box 1 (HMGB1), a nuclear protein, acts as a pro-inflammatory cytokine by activating receptor for advanced glycation end-products (RAGE) in the extracellul...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.15-188
更新日期:2016-01-01 00:00:00
abstract::The objective of the present prospective multicenter case-control study was to investigate the long-term clinical outcome (5 years) of primary stenting compared to primary percutaneous transluminal coronary angioplasty (PTCA) without stenting (POBA) in patients with acute myocardial infarction at 7 cardiovascular cent...
journal_title:International heart journal
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1536/ihj.47.47
更新日期:2006-01-01 00:00:00
abstract::Epicardial adipose tissue (EAT) is presumed to play an important role in the development of coronary artery disease (CAD). The purpose of our study was to examine the influence of EAT volume measured by cardiac CT on the severity and presence of CAD. A total of 209 subjects (114 normal subjects and 95 patients with CA...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.13-303
更新日期:2014-01-01 00:00:00
abstract::The relationship between mild-to-moderate renal dysfunction and cardiac diastolic dysfunction and cardiac events in patients with nonischemic dilated cardiomyopathy (NDCM) has not been fully elucidated. The aim of this study was to investigate the relationship between renal and cardiac function, as well as clinical ou...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.52.366
更新日期:2011-01-01 00:00:00
abstract::Everolimus (EVL), one of the mammalian targets of rapamycin, is a next generation immunosuppressant that may have accessory anti-proliferative effects in heart transplant (HTx) recipients. However, little is known about the clinical relationship between EVL and regression of cardiac hypertrophy. A total of 42 HTx reci...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.15-320
更新日期:2016-01-01 00:00:00
abstract::This study aimed to evaluate whether the heart is the target organ of endogenous atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in patients with heart failure (HF) with reduced ejection fraction (HFrEF).We measured the plasma levels of cyclic guanosine monophosphate (cGMP), which is a second mess...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-379
更新日期:2020-01-31 00:00:00
abstract::To assess the potential advantages of minimally invasive surgery using a single femoral venous drainage method versus femoral venous and superior vena cava or jugular venous drainage method during repeat tricuspid valve surgery.From January 2010 to December 2016, 50 repeat tricuspid valve procedures were performed usi...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.17-169
更新日期:2018-05-30 00:00:00
abstract::The aim of the present study was to determine whether symptoms of atrial fibrillation (AF) differ between patients with and without subsequent permanent AF. Sixty-four patients (68 +/- 10 years old, 45 males) were recruited. AF follow-up was started at the age of 61 +/- 10 years and accomplished in a median period of ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.51.242
更新日期:2010-07-01 00:00:00
abstract::Music therapy (MT) has been used in geriatric nursing hospitals, but there has been no extensive research into whether it actually has beneficial effects on elderly patients with cerebrovascular disease (CVD) and dementia. We investigated the effects of MT on the autonomic nervous system and plasma cytokine and catech...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.50.95
更新日期:2009-01-01 00:00:00
abstract::Uninterrupted anticoagulation therapy during atrial fibrillation (AF) ablation minimizes the risk of periprocedural thromboembolic events. Although the use of direct oral anticoagulants (DOACs) has rapidly developed in patients undergoing AF ablation, no antidote is available for factor Xa inhibitors. We sought to inv...
journal_title:International heart journal
pub_type: 临床试验,杂志文章
doi:10.1536/ihj.19-143
更新日期:2019-11-30 00:00:00
abstract::A 19 year-old woman who underwent corrective surgery for an atrial septal defect (ASD) and ventricular septal defect (VSD) 12 years previously presented with pulmonary hypertension. Cardiac catheterization showed a fistula between the right subclavian artery and vena jugularis interna. In this case, a rare example of ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.46.551
更新日期:2005-05-01 00:00:00
abstract::Supraventricular tachycardia (SVT) was observed in a 13-year-old male patient with complex clinical features that included univentricular heart with single atrium, pulmonary atresia, and polysplenia syndrome. During electrophysiologic study, atrial burst stimuli reproducibly induced and terminated the SVT, while the o...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.48.253
更新日期:2007-03-01 00:00:00
abstract::High sensitive C-reactive protein (hs-CRP) levels are associated with short- and long-term mortality in patients with acute coronary syndrome (ACS). We investigated whether baseline hs-CRP levels are associated with burden of coronary atherosclerosis assessed by SYNTAX score (SXScore).We enrolled 321 patients with ACS...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.14-299
更新日期:2015-01-01 00:00:00
abstract::The aim of this study was to investigate the effect on mortality of torsemide and a combination of loop diuretics (furosemide + torsemide) in contemporary practice in patients with chronic heart failure (HF).We investigated patients with HF in the Heart Failure Center of Fuwai Hospital from 2009 to 2013 who were disch...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.17-522
更新日期:2018-07-31 00:00:00
abstract::The clinical scenario, which is based on systolic blood pressure (SBP) upon admission, is useful for classifying and determining initial treatment for acute heart failure (HF). However, the prognostic significance of SBP following the initial treatment is unclear.The Japanese Heart Failure Syndrome with Preserved Ejec...
journal_title:International heart journal
pub_type: 杂志文章,多中心研究
doi:10.1536/ihj.18-699
更新日期:2019-07-27 00:00:00
abstract::Heart failure (HF) is a disease with high morbidity and mortality. In patients with HF, decreased cardiac output and blood redistribution results in decreased intestinal perfusion and destruction of intestinal barrier. Microorganisms and endotoxins can migrate into the blood circulation, aggravating systemic inflammat...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-372
更新日期:2020-03-28 00:00:00
abstract::The aim of the present study was to determine if there is any association between white coat hypertension (WCH) and body mass index. The study was performed in two phases. In the first phase, we studied consecutive underweight patients, while in the second phase, age-matched consecutive normal weight, overweight, and ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.48.605
更新日期:2007-09-01 00:00:00
abstract::Although atrial ischemic damage is an atrial fibrillation (AF) risk factor, the impact of atrial branches' occlusion on AF development after acute myocardial infarction (AMI) is unclear. Therefore, this study's purpose was to identify predictors of new-onset AF with regard to atrial branches' occlusion. We retrospecti...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-713
更新日期:2019-11-30 00:00:00
abstract::Various surgical techniques have been proposed for treating aortic arch aneurysm (AAA); however, the optimal treatment has not been well defined. This study introduces a new aortic arch inclusion technique with frozen elephant trunk (FET) for AAA treatment.A retrospective analysis was performed among 22 patients for A...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-069
更新日期:2020-11-28 00:00:00
abstract::Apelin was proved to attenuate cardiac interstitial fibrosis. However, the association between apelin level and myocardial fibrosis in patients with hypertrophic cardiomyopathy (HCM) is still unclear.This study aims to determine whether apelin is associated with myocardial fibrosis in HCM and investigate the predictiv...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-598
更新日期:2019-05-30 00:00:00
abstract::The factors responsible for the ST-T wave alternans (STTA) and associated arrhythmias during acute ischemia have not been clarified.In acutely ischemic porcine myocardium, we recorded transmural unipolar and bipolar electrocardiograms and mid-myocardial extracellular K(+) ([K(+)]e) from the center of the ischemic zone...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.15-337
更新日期:2016-05-25 00:00:00
abstract::Vaccines are commonly used as a preventive medicine for infectious diseases worldwide, however, clinical trials on an amyloid beta vaccine for Alzheimer's disease represents a new concept in the field of vaccinations. Several recent studies indicate the potential of therapeutic vaccines as well as classical vaccines a...
journal_title:International heart journal
pub_type: 杂志文章,评审
doi:10.1536/ihj.13-383
更新日期:2014-01-01 00:00:00
abstract::Adaptive servo-ventilation (ASV) is a recently-developed non-invasive therapy that improves the clinical course of heart failure (HF) patients. However, the precise hemodynamic response and predictors of ASV therapy remain uncertain. Overall, 69 patients with New York Heart Association HF class II-IV underwent 10-minu...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.16-489
更新日期:2017-08-03 00:00:00
abstract::This study tested the hypothesis that activated toll-like receptor-4 (TLR-4) is closely related to combined major adverse clinical outcomes (MACO) [defined as advanced Killip score (> or = 3), overt congestive heart failure (CHF) (New York Heart Association functional class > or = 2) or 30-day death] in patients with ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.49.1
更新日期:2008-01-01 00:00:00
abstract::The purpose of this study was to examine the relation between adiponectin levels and subclinical carotid atherosclerosis in patients undergoing coronary artery bypass grafting (CABG). Serum concentrations of adiponectin and carotid intima/media thickness (IMT) were measured in 84 consecutive patients who underwent CAB...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.47.855
更新日期:2006-11-01 00:00:00
abstract::The metabolism of branched-chain amino acids (BCAAs) is reported to change in heart failure (HF) and correlate with cardiac function. However, the effect of BCAAs on HF remains controversial. We investigate the prognostic value of the plasma BCAA level in nonischemic dilated cardiomyopathy (NIDCM).This study enrolled ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-010
更新日期:2020-07-30 00:00:00
abstract::Acute aortic dissection (AAD) is a life-threatening cardiovascular disease with high mortality. Hypertension is a well known risk factor of AAD. There have been previous reports about the association between circadian variation of blood pressure (BP) and cardiovascular events. However, little is known about the associ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.14-328
更新日期:2015-05-13 00:00:00
abstract::DNA damage in the peripheral blood leukocytes (PBL) of patients with coronary artery disease (CAD) was investigated using the sensitive alkaline single cell gel electrophoresis (SCGE)/comet assay.This case-control study consisted of CAD patients (n = 200; mean age, 59.04 ± 0.75 years) undergoing treatment at local hos...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.16-190
更新日期:2017-04-06 00:00:00