Induction of c-fos mRNA expression by pure pressure overload in cultured cardiac myocytes.

abstract：:Our previous study showed that pravastatin prevents ischemia and reperfusion-induced lethal ventricular fibrillation in rats. This study explored whether pravastatin decreases myocardial infarct size and this effect is associated with endothelial nitric oxide synthase (eNOS) expression in myocardium. Rats were treated...

journal_title：International heart journal

authors： Li H,Wang C,Sun J,Liu C,Li N,Chen J

更新日期：2018-01-01 00:00:00

abstract：:While physiological levels of nitric oxide (NO) protect the endothelium and have vasodilatory effects, excessive NO has adverse effects on the cardiovascular system. Recently, new NO-releasing pharmacodynamic hybrids of angiotensin II (Ang II) type 1 (AT1) receptor blockers (ARBs) have been developed.We analyzed wheth...

journal_title：International heart journal

authors： Yahiro E,Miura S,Suematsu Y,Matsuo Y,Arimura T,Kuwano T,Imaizumi S,Iwata A,Uehara Y,Saku K

更新日期：2015-01-01 00:00:00

abstract：:The aim of the present study was to determine if prednisone, a glucocorticoid, added to conventional treatment for patients with decompensated congestive heart failure (DCHF) refractory to the conventional care, results in significant relief of congestive symptoms and improvement of clinical status. Diuretic-based str...

journal_title：International heart journal

authors： Zhang H,Liu C,Ji Z,Liu G,Zhao Q,Ao YG,Wang L,Deng B,Zhen Y,Tian L,Ji L,Liu K

更新日期：2008-09-01 00:00:00

abstract：:Vagus nerve stimulation (VNS), targeting the imbalanced autonomic nervous system, is a promising therapeutic approach for chronic heart failure (HF). Moreover, calcium cycling is an important part of cardiac excitation-contraction coupling (ECC), which also participates in the antiarrhythmic effects of VNS. We hypothe...

journal_title：International heart journal

authors： Zhang Y,Chen A,Song L,Li M,Luo Z,Zhang W,Chen Y,He B

更新日期：2016-05-25 00:00:00

abstract：:Same-day discharge transradial percutaneous coronary intervention (TRI) has been reported to be safe and feasible in Western countries. However, Asia has not produced any reports related to this matter. The present study explored the safety and feasibility of patients with indications for TR coronary angiography and a...

journal_title：International heart journal

authors： Chung WJ,Fang HY,Tsai TH,Yang CH,Chen CJ,Chen SM,Cheng CI,Fang CY,Hsieh YK,Hang CL,Yip HK,Wu CJ

更新日期：2010-01-01 00:00:00

abstract：:microRNA-99a (miR-99a) is recently recognized as a key regulator in various cancers and cardiovascular diseases. In the present study, we sought to investigate the effects of miR-99a in rat cardiomyocyte H9c2 cells against oxidative injury induced by lipopolysaccharide (LPS).MTT assay, reactive oxygen species (ROS) as...

journal_title：International heart journal

authors： Jing R,Zhou Z,Kuang F,Huang L,Li C

更新日期：2017-05-31 00:00:00

abstract：:The current study aimed to identify risk factors for atrial fibrillation (AF) detected during routine medical checkups of male workers in Japan. A nested case-control study was conducted using retrospective data from January 1998 to December 2006 collected at a hospital in Ishikawa Prefecture. Cases were those first d...

journal_title：International heart journal

authors： Minami M,Kobayashi Y,Toyokawa S,Inoue K,Takeshita Y

更新日期：2009-07-01 00:00:00

abstract：:A prospective observational study was conducted to evaluate the predictive value of interleukin-18 (IL-18) for major adverse cardiovascular events (MACEs) in hemodialysis patients. A total of 85 participants (45 hemodialysis patients and 40 healthy volunteers) with a mean age of 56.3 years were enrolled in this study....

journal_title：International heart journal

authors： Wang S,Chen F,Yang S,Shi J

更新日期：2018-07-31 00:00:00

abstract：:Discrimination between atrioventricular node reentry tachycardia (AVNRT) and orthodromic reciprocating tachycardia (ORT) during an electrophysiological study is sometimes challenging. This study aimed to investigate if the difference in the local VA (ventricle-atrium) interval during ventricular entrainment pacing and...

journal_title：International heart journal

authors： He Q,Lei S,Jia FP,Gao LY,W X Zhu D

更新日期：2018-01-27 00:00:00

abstract：:Apelin was proved to attenuate cardiac interstitial fibrosis. However, the association between apelin level and myocardial fibrosis in patients with hypertrophic cardiomyopathy (HCM) is still unclear.This study aims to determine whether apelin is associated with myocardial fibrosis in HCM and investigate the predictiv...

journal_title：International heart journal

authors： Zhou Y,Yuan J,Wang Y,Qiao S

更新日期：2019-05-30 00:00:00

abstract：:In patients requiring an implantable cardioverter defibrillator (ICD), the combined use of a prior pacemaker and a subcutaneous ICD (S-ICD) could be an alternative treatment option to implantation of new leads or upgrading of pacemakers to an ICD if vascular access is limited. Here, we assessed the prevalence of S-ICD...

journal_title：International heart journal

authors： Kawabata M,Goya M,Takahashi Y,Maeda S,Yagishita A,Shirai Y,Kaneko M,Shiohira S,Hirao K

更新日期：2018-09-26 00:00:00

abstract：:This study tested the therapeutic impact of double-loading dose (i.e., 600 mg) versus standard-loading dose (i.e., 300 mg) of clopidogrel on ST-segment-elevation-myocardial-infarction (STEMI) patients undergoing primary-coronary-intervention (PCI).Between January 2005 and December 2013, a total of 1461 STEMI patients ...

journal_title：International heart journal

authors： Tong MS,Sung PH,Liu CF,Chen KH,Chung SY,Chua S,Chen CJ,Lee WC,Chai HT,Yip HK,Chang HW

更新日期：2017-10-21 00:00:00

abstract：:After the new left ventricular ejection fraction (LVEF) classification criteria emerged, many studies have focused on the differences between heart failure (HF) with reduced EF (HFrEF), HF with midrange EF (HFmrEF), and HF with preserved EF (HFpEF). However, the lack of consensus on sex-related differences in prognosi...

journal_title：International heart journal

authors： Wang C,Zhou Y,Zhong R,Bao Y,Li Z,Tian J

更新日期：2020-11-28 00:00:00

abstract：:Flexible, in vivo maneuverable electrophysiology mapping techniques are not available in rat models. A novel cardiac stereotactic electrophysiology epicardial mapping system (CREAMS) allows for various measurements, including: (1) recording unipolar electrograms at multiple sites; (2) positioning of mapped sites and p...

journal_title：International heart journal

authors： Fan B,Wang H,Wu T,Li Y,Lin Z,Li M,Li Q,Zhang W,Zheng Q

更新日期：2019-03-20 00:00:00

abstract：:A 37 year-old female who had suffered from arteritis for 20 years underwent a Bentall operation. Since severe stenosis was observed in her left main coronary artery (LMCA) the following year, a minimally invasive direct coronary artery bypass (MIDCAB) operation was performed. Unfortunately, she again complained of ang...

journal_title：International heart journal

authors： Sakai H,Oyama N,Kishimoto N,Takahashi M,Urasawa K,Tsutsui H

更新日期：2006-09-01 00:00:00

abstract：:Antihypertensive drugs have been linked to new-onset diabetes (NOD); however, the effects of these drugs on the development of NOD in elderly Taiwanese hypertensive patients have not been well determined. We examined the association between antihypertensive drug therapy and the risk of NOD in a population-based study....

journal_title：International heart journal

authors： Liou YS,Ma T,Tien L,Chien C,Chou P,Jong GP

更新日期：2008-03-01 00:00:00

abstract：:Implantation of a paclitaxel- or sirolimus-eluting stent (SES) may be associated with endothelial dysfunction. In the present study, we compared coronary endothelial function after zotarolimus-eluting stent (ZES) implantation to that after SES implantation. Patients who had one stent implantation for a single lesion i...

journal_title：International heart journal

authors： Shin DI,Seung KB,Kim PJ,Chang K,Choi JK,Jeon DS,Kim MJ,Lee MY,Chung WS

更新日期：2008-11-01 00:00:00

abstract：:Renal injury is an important factor for worsening outcome in acute decompensated heart failure (ADHF). An 81-year-old woman was admitted due to ADHF with dyspnea and mild peripheral edema. The patient was managed with intravenous administration of atrial natriuretic peptide (ANP) at a dose of 0.0125 μg/kg/minute, whic...

journal_title：International heart journal

authors： Kamiya M,Sato N,Akiya M,Okazaki H,Takahashi Y,Mizuno K

更新日期：2013-01-01 00:00:00

abstract：:Since diabetes mellitus (DM) is the most common cause of heart failure (HF), it is critically important to clarify whether incretin hormones including glucagon-like peptide-1 (GLP-1), which play an important role in blood glucose control, mediate cardioprotection. There are many lines of basic research evidence indica...

journal_title：International heart journal

authors： Takahashi A,Ihara M,Yamazaki S,Asanuma H,Asakura M,Kitakaze M

更新日期：2015-01-01 00:00:00

abstract：:Several studies have reported that the left ventricular (LV) lead implant success rate ranges between 88.0% and 92.4%. Coronary venous anatomy differs among patients thus, necessitating multiple types of leads. To date, the implant success rate among Japanese patients utilizing a pre-specified family LV leads (includi...

journal_title：International heart journal

authors： Ando K,Kanda S,Miura F,Ashikaga K,Ehara N,Sakai Y,Furukawa T,Yoshimura H,Adachi K

更新日期：2018-09-26 00:00:00

abstract：:A 68-year-old female with acute coronary syndrome was transferred to our hospital. Emergency coronary angiography showed 90% stenosis with severe calcification in the proximal right coronary artery (RCA). Intravascular ultrasound (IVUS) images were obtained and showed circumferential heavy calcification without any ev...

journal_title：International heart journal

authors： Goryo Y,Kume T,Kobayashi Y,Okamoto H,Kawamura A,Fukuhara K,Koyama T,Yamada R,Imai K,Neishi Y,Uemura S

更新日期：2017-02-07 00:00:00

abstract：:Tolvaptan is a highly selective and orally effective arginine vasopressin V2 receptor antagonist, and is potentially useful for the treatment of heart failure (HF) patients. However, the renoprotective effect of long-term tolvaptan therapy and its underlying mechanisms remain unknown. We evaluated the effects of chron...

journal_title：International heart journal

authors： Ishikawa M,Kobayashi N,Sugiyama F,Onoda S,Ishimitsu T

更新日期：2013-01-01 00:00:00

abstract：:We present a 16-year-old male patient with hypoplastic left heart syndrome who developed protein-losing enteropathy (PLE) and plastic bronchitis (PB) after a Fontan operation. He received medical therapies, including albumin infusion, unfractionated heparin, and high-dose anti-aldosterone therapy but could not obtain ...

journal_title：International heart journal

authors： Okada S,Muneuchi J,Nagatomo Y,Nonaka K,Iida C,Shirouzu H,Matsuoka R,Watanabe M,Joo K

更新日期：2018-07-31 00:00:00

abstract：:The objective of the present prospective multicenter case-control study was to investigate the long-term clinical outcome (5 years) of primary stenting compared to primary percutaneous transluminal coronary angioplasty (PTCA) without stenting (POBA) in patients with acute myocardial infarction at 7 cardiovascular cent...

journal_title：International heart journal

authors： Sasao H,Tsuchihashi K,Nagao K,Miyamoto K,Murakami H,Doi A,Shimoshige S,Hasegawa K,Kyuma M,Noda R,Shimamoto K

更新日期：2006-01-01 00:00:00

abstract：:Atherosclerosis is a multifactorial vascular disease characterized by formation of inflammatory lesions. Secretory phospholipase A2, group IIA (sPLA2-IIA) is involved in this process and plays a critical role. However, the exact role of sPLA2-IIA in cardiovascular inflammation is more complicated and remains unclear. ...

journal_title：International heart journal

authors： Xie Q,Zhang D

更新日期：2017-02-07 00:00:00

abstract：:Prevalent atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM) represents an important issue with regard to stroke events caused by embolization and is associated with high mortality. Increased epicardial adipose tissue (EAT), which shows high metabolic activity, can locally influence the activi...

journal_title：International heart journal

authors： Muhib S,Fujino T,Sato N,Hasebe N

更新日期：2013-01-01 00:00:00

abstract：:Coronary artery ectasia (CAE) is characterised by irregular, diffuse, saccular, or fusiform dilatation of the coronary arteries. Although the underlying mechanisms are not fully understood, CAE is considered to be an original form of vascular remodelling in response to atherosclerosis. However, it is not clear why som...

journal_title：International heart journal

authors： Uyarel H,Okmen E,Tartan Z,Kasikcioglu H,Dayi SU,Karabulut A,Uzunlar B,Samur H,Cam N

更新日期：2005-01-01 00:00:00

abstract：:Vaccines are commonly used as a preventive medicine for infectious diseases worldwide, however, clinical trials on an amyloid beta vaccine for Alzheimer's disease represents a new concept in the field of vaccinations. Several recent studies indicate the potential of therapeutic vaccines as well as classical vaccines a...

journal_title：International heart journal

authors： Nakagami H,Koriyama H,Morishita R

更新日期：2014-01-01 00:00:00

abstract：:High mobility group box 1 (HMGB1), which has properties similar to those of proinflammatory cytokines, is released from activated immune cells and necrotic cells. It is known that cardiopulmonary bypass (CPB) induces systemic inflammation and aortic cross-clamping induces myocardial ischemia. This study was conducted ...

journal_title：International heart journal

authors： Haque A,Kunimoto F,Narahara H,Okawa M,Hinohara H,Kurabayashi M,Saito S

更新日期：2011-01-01 00:00:00

abstract：:Steam pop and intramural charring have been reported during cooled-tip radiofrequency catheter ablation (RFCA). We studied the feasibility of temperature-controlled cooled-tip RFCA in the canine heart.An internally cooled ablation catheter was inserted into the left ventricle. A custom-made radiofrequency (RF) generat...

journal_title：International heart journal

authors： Watanabe I,Nuo M,Okumura Y,Ohkubo K,Ashino S,Kofune M,Kofune T,Nakai T,Kasamaki Y,Hirayama A

更新日期：2010-05-01 00:00:00