microRNA-99a Reduces Lipopolysaccharide-Induced Oxidative Injury by Activating Notch Pathway in H9c2 Cells.

abstract：:Vaccines are commonly used as a preventive medicine for infectious diseases worldwide, however, clinical trials on an amyloid beta vaccine for Alzheimer's disease represents a new concept in the field of vaccinations. Several recent studies indicate the potential of therapeutic vaccines as well as classical vaccines a...

journal_title：International heart journal

authors： Nakagami H,Koriyama H,Morishita R

更新日期：2014-01-01 00:00:00

abstract：:Heart failure (HF) is a disease with high morbidity and mortality. In patients with HF, decreased cardiac output and blood redistribution results in decreased intestinal perfusion and destruction of intestinal barrier. Microorganisms and endotoxins can migrate into the blood circulation, aggravating systemic inflammat...

journal_title：International heart journal

authors： Jin B,Ji F,Zuo A,Liu H,Qi L,He Y,Wang Q,Zhao P

更新日期：2020-03-28 00:00:00

abstract：:This study tested the therapeutic impact of double-loading dose (i.e., 600 mg) versus standard-loading dose (i.e., 300 mg) of clopidogrel on ST-segment-elevation-myocardial-infarction (STEMI) patients undergoing primary-coronary-intervention (PCI).Between January 2005 and December 2013, a total of 1461 STEMI patients ...

journal_title：International heart journal

authors： Tong MS,Sung PH,Liu CF,Chen KH,Chung SY,Chua S,Chen CJ,Lee WC,Chai HT,Yip HK,Chang HW

更新日期：2017-10-21 00:00:00

abstract：:Implantation of a paclitaxel- or sirolimus-eluting stent (SES) may be associated with endothelial dysfunction. In the present study, we compared coronary endothelial function after zotarolimus-eluting stent (ZES) implantation to that after SES implantation. Patients who had one stent implantation for a single lesion i...

journal_title：International heart journal

authors： Shin DI,Seung KB,Kim PJ,Chang K,Choi JK,Jeon DS,Kim MJ,Lee MY,Chung WS

更新日期：2008-11-01 00:00:00

abstract：:The association between endothelial function, evaluated using flow-mediated dilatation (FMD), and the severity of coronary artery disease remains to be elucidated.A total of 245 consecutive patients with stable angina were prospectively enrolled. FMD was evaluated in the brachial artery before percutaneous coronary in...

journal_title：International heart journal

authors： Nemoto T,Minami Y,Yamaoka-Tojo M,Sato T,Muramatsu Y,Kakizaki R,Fujiyoshi K,Hashimoto T,Meguro K,Shimohama T,Tojo T,Ako J

更新日期：2019-05-30 00:00:00

abstract：:Activation of mineralocorticoid receptor (MR) is shown in resistant hypertension including diabetes mellitus. Although protein kinase C (PKC) signaling is involved in the pathogenesis of diabetic complications, an association between PKC and MR is not known. Activation of PKCα and PKCβ by TPA (12-O-Tetradecanoylphorbo...

journal_title：International heart journal

authors： Hayashi T,Shibata H,Kurihara I,Yokota K,Mitsuishi Y,Ohashi K,Murai-Takeda A,Jo R,Ohyama T,Sakamoto M,Tojo K,Tajima N,Utsunomiya K,Itoh H

更新日期：2017-10-21 00:00:00

abstract：:Catheter ablation has been established to be an effective therapy for drug-refractory paroxysmal AF and is recommended as the treatment of choice for many patients, including those with a permanent pacemaker (PM). However, the clinical efficacy of catheter ablation of paroxysmal AF in patients with a permanent PM for ...

journal_title：International heart journal

authors： Wu JT,Dong JZ,Wang SL,Chu YJ,Wang LX,Yang CK

更新日期：2014-01-01 00:00:00

abstract：:The long-term prognosis for up to 20 years of patients who have undergone percutaneous transvenous mitral commissurotomy (PTMC) for mitral stenosis (MS) is unknown.We examined 77 of 93 patients (83%) with MS and who underwent PTMC from 1989 to 2002 at our institute, as well as the occurrence of either one of the follo...

journal_title：International heart journal

authors： Kubota N,Ozaki K,Hoyano M,Nishida K,Takano T,Okubo T,Kimura S,Yanagawa T,Kashimura T,Minamino T

更新日期：2020-11-28 00:00:00

abstract：:An aorto-cutaneous fistula is a rare complication that occurs after aortic surgery. Due to its rarity, postoperative complications are not normally highlighted in most standard teaching. We report here a case of aorto-cutaneous fistula after surgical treatment of a Stanford type A aortic dissection (AD) in a 67-year-o...

journal_title：International heart journal

authors： Zhao C,Zhu Z,Zheng X,Liu K

更新日期：2018-01-27 00:00:00

abstract：:Ablation catheters with multiple electrodes are effective for the creation of linear atrial lesions but are associated with an increased risk of coagulum formation. In an animal study, we used a novel 9Fr deflectable ablation catheter with two saline/foam electrode pocket covered with 20 mm tubing. Each pocket contain...

journal_title：International heart journal

authors： Watanabe I,Min N,Okumura Y,Kofune M,Ashino S,Ohkubo K,Nakai T,Kunimoto S,Kasamaki Y,Hirayama A

更新日期：2009-05-01 00:00:00

abstract：:Decreased Transthyretin (TTR) can be observed in heart failure patients with malnutrition evaluated by the Mini Nutritional Assessment (MNA). This study investigated whether a combination of different nutritional assessment methods would be useful for assessing prognosis in patients with acute decompensated heart fail...

journal_title：International heart journal

authors： Suzuki N,Kida K,Suzuki K,Harada T,Akashi YJ

更新日期：2015-01-01 00:00:00

abstract：:Percutaneous coronary interventions to the proximal left anterior descending artery (pLAD)-acute myocardial infarction (AMI) are still challenging, especially in the ostial pLAD. Clinical outcomes of the ostial pLAD-AMI were not well investigated. The aim of the present study was to compare clinical outcomes of the os...

journal_title：International heart journal

authors： Yamamoto K,Sakakura K,Akashi N,Watanabe Y,Noguchi M,Taniguchi Y,Wada H,Momomura SI,Fujita H

更新日期：2019-01-25 00:00:00

abstract：:Everolimus (EVL), one of the mammalian targets of rapamycin, is a next generation immunosuppressant that may have accessory anti-proliferative effects in heart transplant (HTx) recipients. However, little is known about the clinical relationship between EVL and regression of cardiac hypertrophy. A total of 42 HTx reci...

journal_title：International heart journal

authors： Imamura T,Kinugawa K,Nitta D,Kinoshita O,Nawata K,Ono M

更新日期：2016-01-01 00:00:00

abstract：:Atherosclerosis is a multifactorial vascular disease characterized by formation of inflammatory lesions. Secretory phospholipase A2, group IIA (sPLA2-IIA) is involved in this process and plays a critical role. However, the exact role of sPLA2-IIA in cardiovascular inflammation is more complicated and remains unclear. ...

journal_title：International heart journal

authors： Xie Q,Zhang D

更新日期：2017-02-07 00:00:00

abstract：:Proinflammatory cytokine responses might occur in elderly individuals with cardiovascular (CV) disease, cerebro-vascular (CVA) disease, and/or pulmonary disease (PD). Spiritual activation is an important coping mechanism, since psychiatric depression is an important risk factor for these individuals. Thirty-three very...

journal_title：International heart journal

authors： Kurita A,Takase B,Shinagawa N,Kodani E,Okada K,Iwahara S,Kusama Y,Atarashi H

更新日期：2011-01-01 00:00:00

abstract：:A 52-year-old woman with intermittent complete atrioventricular (AV) block detected on exercise was admitted to the hospital. Echocardiography revealed lesions on the right ventricular side of the interventricular septum and free wall of the basal inferolateral area. Gadolinium-enhanced cardiovascular magnetic resonan...

journal_title：International heart journal

authors： Fujimoto R,Asano T,Maezawa H,Shimojima H,Tsujiuchi M,Hori Y,Ebato M,Suzuki H

更新日期：2018-11-28 00:00:00

abstract：:Uninterrupted anticoagulation therapy during atrial fibrillation (AF) ablation minimizes the risk of periprocedural thromboembolic events. Although the use of direct oral anticoagulants (DOACs) has rapidly developed in patients undergoing AF ablation, no antidote is available for factor Xa inhibitors. We sought to inv...

journal_title：International heart journal

authors： Aoyama D,Miyazaki S,Hasegawa K,Kaseno K,Ishikawa E,Mukai M,Miyahara K,Aiki T,Matsui A,Yamaguchi J,Shiomi Y,Tama N,Ikeda H,Fukuoka Y,Morishita T,Ishida K,Uzui H,Tada H

更新日期：2019-11-30 00:00:00

abstract：:Sleep-disordered breathing (SDB) is frequently observed in patients with congestive heart failure. Recent studies have shown that SDB negatively affects the onset of congestive heart failure; however, no studies have addressed the relationship between the level of SDB and the onset time of acute dyspnea. We hypothesiz...

journal_title：International heart journal

authors： Yoneyama K,Osada N,Shimozato T,Ishibashi Y,Hayashi A,Takahashi E,Kida K,Suzuki K,Tamura M,Inoue K,Akashi YJ,Omiya K,Miyake F,Izawa KP,Watanabe S

更新日期：2008-07-01 00:00:00

abstract：:A 14 year-old boy developed infective endocarditis of the mitral valve caused by Methicillin-sensitive Staphylococcus aureus and became comatose. Isolated basilar artery dissection was initially observed on the 3rd day by magnetic resonance imaging (MRI), ie, it did not exist on day 1. He underwent successful urgent m...

journal_title：International heart journal

authors： Kawano A,Masutani S,Inui A,Honma H,Igarashi T,Tsuneoka H,Sakamoto W,Sakurai Y,Dembo T,Imanaka K

更新日期：2021-01-16 00:00:00

abstract：:Most previous studies have examined the effects of antihypertensive drugs in hypertensive animals for only a few months, and little information has been provided as to the protective effects of lifetime antihypertensive medication against cardiovascular organ injury. In this study, spontaneously hypertensive rats (SHR...

journal_title：International heart journal

authors： Ishimitsu T,Honda T,Ohno E,Furukata S,Sudo Y,Nakano N,Takahashi T,Ono H,Matsuoka H

更新日期：2010-01-01 00:00:00

abstract：:High plasma HDL-cholesterol (HDL-c) is a well-established protective factor in coronary artery disease (CAD). One of its potential protective mechanisms is the inhibition of the cytokine-induced upregulation of expression of cellular adhesion molecules (CAMs). High sCAM levels were found to be associated with low HDL-...

journal_title：International heart journal

authors： Stanojević NB,Ivanović ZJ,Djurovic S,Kalimanovska VS,Spasić S,Ostrić DK,Memon L

更新日期：2005-07-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling leading to right ventricular hypertrophy (RVH) and failure. Peroxisome proliferator-activated receptor γ (PPARγ), a member of nuclear receptors, has been proved to ameliorate PAH. However, its effect on PAH-induced right ventricula...

journal_title：International heart journal

authors： Xu Y,Gu Q,Liu N,Yan Y,Yang X,Hao Y,Qu C

更新日期：2017-12-12 00:00:00

abstract：:Tenascin-C (TNC) is involved in aortic disease pathophysiology. This study aims to evaluate TNC's value for predicting in-hospital death in acute aortic dissection (AD).We prospectively enrolled consecutive patients with suspected acute AD within 48 hours from symptom onset. Serum TNC and C-reactive protein (CRP) leve...

journal_title：International heart journal

authors： Guo T,Zhou X,Zhu A,Peng W,Zhong Y,Chai X

更新日期：2019-07-27 00:00:00

abstract：:The aim of this study was to investigate the effects of taurine (Tau) on primary cultured neonatal myocardial cells treated with hydrogen peroxide (H2O2) and the underlying mechanism. Primary cardiac myocytes from neonatal Wistar rats were pre-incubated with Tau, and its effects on cell viability and expression of CaM...

journal_title：International heart journal

authors： Wang J,Qi C,Liu L,Zhao L,Cui W,Tian Y,Liu B,Li J

更新日期：2018-01-27 00:00:00

abstract：:This study aimed to evaluate the potential associations of intermediate monocytes (CD14(++)CD16(+)) with myocardial remodelling in ST segment elevation myocardial infarction (STEMI) patients with diabetes.A total of 67 STEMI patients with diabetes were enrolled. The control group consisted of 65 STEMI patients without...

journal_title：International heart journal

authors： Lu W,Zhang Z,Fu C,Ma G

更新日期：2015-01-01 00:00:00

abstract：:Although calcium channel blockers (CCB) are expected to improve the augmentation index (AI) in CKD patients, the potential effect of benidipine on AI has been poorly studied.The present study aimed to compare the effect of benidipine and amlodipine in the treatment of CKD patients as measured through AI and urinary al...

journal_title：International heart journal

authors： Takayama T,Yoda S,Yajima Y,Kasamaki Y,Kunimoto S,Kanai T,Hirayama A

更新日期：2016-01-01 00:00:00

abstract：:The literature on malignant cardiac tumors is relatively limited because they are rare, especially among the Chinese population. We analyzed 14 patients diagnosed with malignant cardiac tumors in Fuwai Hospital and present the results of surgical treatments on the tumors. The mean age at tumor diagnosis was 47 years i...

journal_title：International heart journal

authors： Guo GR,Wang X,Yang J,Chen L,Song JP,Wang LQ

更新日期：2019-07-27 00:00:00

abstract：:Hyperglycemia is an established risk factor of coronary artery disease (CAD). However, hyperglycemia with preserved pancreatic β cell function induces hyperinsulinemia to correct the glucose profile and may even result in reactive hypoglycemia (RH), which induces an inflammatory response. In this study, the incidence ...

journal_title：International heart journal

authors： Murata M,Adachi H,Oshima S,Kurabayashi M

更新日期：2018-07-31 00:00:00

abstract：:Music therapy (MT) has been used in geriatric nursing hospitals, but there has been no extensive research into whether it actually has beneficial effects on elderly patients with cerebrovascular disease (CVD) and dementia. We investigated the effects of MT on the autonomic nervous system and plasma cytokine and catech...

journal_title：International heart journal

authors： Okada K,Kurita A,Takase B,Otsuka T,Kodani E,Kusama Y,Atarashi H,Mizuno K

更新日期：2009-01-01 00:00:00

abstract：:The natural history of asymptomatic individuals with a Brugada-type electrocardiogram (ECG) is still controversial. In this study, we evaluated ventricular fibrillation (VF) inducibility in Brugada-type ECG patients and compared it with other risk factors to clarify the significance of these data on their prognosis. T...

journal_title：International heart journal

authors： Imaki R,Niwano S,Fukaya H,Sasaki S,Yuge M,Hirasawa S,Sato D,Sasaki T,Moriguchi M,Izumi T

更新日期：2006-03-01 00:00:00