Mechanism of pressure-overload right ventricular hypertrophy in infant rabbits.

abstract：:Sirt1 is a highly conserved nicotinamide adenine dinucleotide (NAD(+)) dependent histone deacetylase which plays an important role in heart diseases. Studies performed with Sirt1 activators indicated that it protects cells from ischemia/ reperfusion (I/R) injury. The protective effects of H2S against I/R injury also h...

journal_title：International heart journal

authors： Hu MZ,Zhou B,Mao HY,Sheng Q,Du B,Chen JL,Pang QF,Ji Y

更新日期：2016-07-27 00:00:00

abstract：:The usefulness of coronary magnetic resonance angiography (cMRA) has been reported, although the difference in the diagnostic accuracy of different protocols has not been established.We compared conventional coronary angiography (CAG) and cMRA, conducted within 6 months in 24 consecutive patients between September 201...

journal_title：International heart journal

authors： Namba Y,Fuke S,Kashihara Y,Tanaka M,Yumoto A,Saito H,Sato T

更新日期：2016-09-28 00:00:00

abstract：:Electrocardiography (ECG) is used to screen for pulmonary hypertension (PH). However, it is unclear which parameters of ECG are the most useful for screening.ECG parameters related to right ventricular hypertrophy criteria were examined in 145 ECGs of subjects who were suspected to have PH and underwent right heart ca...

journal_title：International heart journal

authors： Miura M,Ikeda S,Yoshida T,Yamagata Y,Nakata T,Koga S,Koide Y,Kawano H,Maemura K

更新日期：2018-01-27 00:00:00

abstract：:Adaptive servo-ventilation (ASV) is a recently-developed non-invasive therapy that improves the clinical course of heart failure (HF) patients. However, the precise hemodynamic response and predictors of ASV therapy remain uncertain. Overall, 69 patients with New York Heart Association HF class II-IV underwent 10-minu...

journal_title：International heart journal

authors： Imamura T,Kinugawa K

更新日期：2017-08-03 00:00:00

abstract：:Mitral and aortic valve regurgitation is commonly found in osteogenesis imperfecta (OI) patients, however, little is known about the myocardial involvement in this disorder. An 82-year-old man with OI developed heart failure and was admitted to our hospital. Echocardiogram revealed severe mitral regurgitation without ...

journal_title：International heart journal

authors： Soma K,Abe H,Takeda N,Shintani Y,Takazawa Y,Kojima T,Fujiu K,Semba H,Yamashita H,Hirata Y,Fukayama M,Nagai R

更新日期：2012-01-01 00:00:00

abstract：:Prevalent atrial fibrillation (AF) in patients with hypertrophic cardiomyopathy (HCM) represents an important issue with regard to stroke events caused by embolization and is associated with high mortality. Increased epicardial adipose tissue (EAT), which shows high metabolic activity, can locally influence the activi...

journal_title：International heart journal

authors： Muhib S,Fujino T,Sato N,Hasebe N

更新日期：2013-01-01 00:00:00

abstract：:The current study aimed to identify risk factors for atrial fibrillation (AF) detected during routine medical checkups of male workers in Japan. A nested case-control study was conducted using retrospective data from January 1998 to December 2006 collected at a hospital in Ishikawa Prefecture. Cases were those first d...

journal_title：International heart journal

authors： Minami M,Kobayashi Y,Toyokawa S,Inoue K,Takeshita Y

更新日期：2009-07-01 00:00:00

abstract：:microRNA-99a (miR-99a) is recently recognized as a key regulator in various cancers and cardiovascular diseases. In the present study, we sought to investigate the effects of miR-99a in rat cardiomyocyte H9c2 cells against oxidative injury induced by lipopolysaccharide (LPS).MTT assay, reactive oxygen species (ROS) as...

journal_title：International heart journal

authors： Jing R,Zhou Z,Kuang F,Huang L,Li C

更新日期：2017-05-31 00:00:00

abstract：:Renal injury is an important factor for worsening outcome in acute decompensated heart failure (ADHF). An 81-year-old woman was admitted due to ADHF with dyspnea and mild peripheral edema. The patient was managed with intravenous administration of atrial natriuretic peptide (ANP) at a dose of 0.0125 μg/kg/minute, whic...

journal_title：International heart journal

authors： Kamiya M,Sato N,Akiya M,Okazaki H,Takahashi Y,Mizuno K

更新日期：2013-01-01 00:00:00

abstract：:The objective of the present prospective multicenter case-control study was to investigate the long-term clinical outcome (5 years) of primary stenting compared to primary percutaneous transluminal coronary angioplasty (PTCA) without stenting (POBA) in patients with acute myocardial infarction at 7 cardiovascular cent...

journal_title：International heart journal

authors： Sasao H,Tsuchihashi K,Nagao K,Miyamoto K,Murakami H,Doi A,Shimoshige S,Hasegawa K,Kyuma M,Noda R,Shimamoto K

更新日期：2006-01-01 00:00:00

abstract：:In this study, we aim to investigate the association of serum uric acid (SUA) with the prevalence of premature ventricular contraction (PVC). The relationship between SUA and the prevalence of PVC in 98,965 subjects (79,034 male subjects, mean age: 51.9 ± 12.6 years old) in the Kailuan cohort study (n = 101,510, age r...

journal_title：International heart journal

authors： Chen Y,Wu S,Li W,Wang B,Lv H,Yang X,Khalid BW,Yin X,Xia Y

更新日期：2018-11-28 00:00:00

abstract：:This study tested the hypothesis that activated toll-like receptor-4 (TLR-4) is closely related to combined major adverse clinical outcomes (MACO) [defined as advanced Killip score (> or = 3), overt congestive heart failure (CHF) (New York Heart Association functional class > or = 2) or 30-day death] in patients with ...

journal_title：International heart journal

authors： Sheu JJ,Chang LT,Chiang CH,Youssef AA,Wu CJ,Lee FY,Yip HK

更新日期：2008-01-01 00:00:00

abstract：:The aim of this study was to evaluate the feasibility and efficacy of the Guidezilla guide extension catheter in a reverse controlled antegrade and retrograde subintimal tracking (CART) technique for chronic total occlusion (CTO) recanalization.We retrospectively collected 80 CTO cases using reverse CART technology fr...

journal_title：International heart journal

authors： Huang Z,Zhang B,Chai W,Ma D,Liao H,Zhong Z,Wang F,Lin J

更新日期：2017-05-31 00:00:00

abstract：:Bleeding complications following percutaneous coronary interventions (PCI) have been closely associated with morbidity and mortality. Although radial arteries have been widely used in current PCI, including primary PCI, transfemoral PCI remains necessary for complex PCI. The purpose of this study was to compare the in...

journal_title：International heart journal

authors： Yamamoto S,Sakakura K,Taniguchi Y,Yamamoto K,Wada H,Momomura SI,Fujita H

更新日期：2018-05-30 00:00:00

abstract：:Low-density lipoprotein (LDL) particles are known to be atherogenic agents in coronary artery diseases. They adjust to other electronegative forms and can be the subject for the enhancement of inflammatory events in vessel subendothelial spaces. The LDL uptake is related to the membrane scavenger receptors, including ...

journal_title：International heart journal

authors： Li Y,Rao Y,Zhu H,Jiang B,Zhu M

更新日期：2020-01-01 00:00:00

abstract：:We experienced a 33-year-old patient with D-looped transposition of the great arteries (D-TGA) and a history of Senning operation who was referred to our institute with cardiogenic shock and subsequently underwent urgent paracorporeal ventricular assist device (VAD) implantation, which was a first in Japan, that was e...

journal_title：International heart journal

authors： Nakamura M,Imamura T,Kuwahara H,Nakagaito M,Yokoyama S,Doi T,Fukahara K,Yoshimura N,Kinugawa K

更新日期：2020-05-30 00:00:00

abstract：:Prognosis of patients with heart failure (HF) remains unclear in Japan and should be determined in a prospective fashion. A prospective cohort of The Shinken Database comprised details on all of the new patients, including both inpatients and outpatients, who visited The Cardiovascular Institute Hospital in 2004-2005....

journal_title：International heart journal

authors： Goda A,Yamashita T,Suzuki S,Ohtsuka T,Uejima T,Oikawa Y,Yajima J,Koike A,Nagashima K,Kirigaya H,Sagara K,Ogasawara K,Isobe M,Sawada H,Aizawa T

更新日期：2009-09-01 00:00:00

abstract：:The aim of the present study was to determine if prednisone, a glucocorticoid, added to conventional treatment for patients with decompensated congestive heart failure (DCHF) refractory to the conventional care, results in significant relief of congestive symptoms and improvement of clinical status. Diuretic-based str...

journal_title：International heart journal

authors： Zhang H,Liu C,Ji Z,Liu G,Zhao Q,Ao YG,Wang L,Deng B,Zhen Y,Tian L,Ji L,Liu K

更新日期：2008-09-01 00:00:00

abstract：:Since diabetes mellitus (DM) is the most common cause of heart failure (HF), it is critically important to clarify whether incretin hormones including glucagon-like peptide-1 (GLP-1), which play an important role in blood glucose control, mediate cardioprotection. There are many lines of basic research evidence indica...

journal_title：International heart journal

authors： Takahashi A,Ihara M,Yamazaki S,Asanuma H,Asakura M,Kitakaze M

更新日期：2015-01-01 00:00:00

abstract：:Despite wide interindividual variability in response to clopidogrel, platelet P2Y(12) ADP receptor inhibition in Japanese patients has not been fully studied using specific methodology. This study compared platelet P2Y(12) ADP receptor inhibition during treatment with clopidogrel versus clopidogrel plus cilostazol in ...

journal_title：International heart journal

authors： Fu Q,Yokoyama N,Takada K,Ishikawa S,Isshiki T

更新日期：2010-01-01 00:00:00

abstract：:Myocardial infarction (MI) occurs when the heart muscle is severely damaged due to a decrease in blood flow from the coronary arteries. During recovery from an MI, cardiac fibroblasts become activated and produce extracellular matrices, contributing to the wound healing process in the damaged heart. Inappropriate acti...

journal_title：International heart journal

authors： Wake M,Takeda N,Isagawa T,Sato T,Nakagama Y,Morioka MS,Hirota Y,Asagiri M,Maemura K,Manabe I,Tanabe K,Komuro I

更新日期：2019-07-27 00:00:00

abstract：:The chronic use of bosentan has been reported to reduce the plasma concentration of sildenafil. However, it remains unclear how sildenafil exerts the effect at reduced concentrations in pulmonary arterial hypertension (PAH) patients chronically treated with bosentan.We examined the hemodynamic effects of sildenafil (5...

journal_title：International heart journal

authors： Hatano M,Yao A,Kinugawa K,Hirata Y,Nagai R

更新日期：2011-01-01 00:00:00

abstract：:Our previous study showed that pravastatin prevents ischemia and reperfusion-induced lethal ventricular fibrillation in rats. This study explored whether pravastatin decreases myocardial infarct size and this effect is associated with endothelial nitric oxide synthase (eNOS) expression in myocardium. Rats were treated...

journal_title：International heart journal

authors： Li H,Wang C,Sun J,Liu C,Li N,Chen J

更新日期：2018-01-01 00:00:00

abstract：:Intraaortic balloon pumping (IABP) is a useful therapy for refractory heart failure. However, the safe duration of this therapy and possible complications due to long-term IABP support remain unclear. In this study, we reviewed retrospectively patients requiring the long-term use of IABP, defined here as 10 days or mo...

journal_title：International heart journal

authors： Oshima K,Morishita Y,Hinohara H,Kadoi Y,Hayashi Y,Tajima Y,Kunimoto F

更新日期：2005-11-01 00:00:00

abstract：:Catheter ablation has been established to be an effective therapy for drug-refractory paroxysmal AF and is recommended as the treatment of choice for many patients, including those with a permanent pacemaker (PM). However, the clinical efficacy of catheter ablation of paroxysmal AF in patients with a permanent PM for ...

journal_title：International heart journal

authors： Wu JT,Dong JZ,Wang SL,Chu YJ,Wang LX,Yang CK

更新日期：2014-01-01 00:00:00

abstract：:DNA damage in the peripheral blood leukocytes (PBL) of patients with coronary artery disease (CAD) was investigated using the sensitive alkaline single cell gel electrophoresis (SCGE)/comet assay.This case-control study consisted of CAD patients (n = 200; mean age, 59.04 ± 0.75 years) undergoing treatment at local hos...

journal_title：International heart journal

authors： Bhat MA,Gandhi G

更新日期：2017-04-06 00:00:00

abstract：:Several studies have revealed that stress after catastrophic disasters can trigger cardiovascular events, however, little is known about its association with the occurrence of heart failure in past earthquakes. The objective of the present study was to determine whether the Great East Japan Earthquake on March 11, 201...

journal_title：International heart journal

authors： Suzuki H,Yamada S,Kamiyama Y,Takeishi Y

更新日期：2014-01-01 00:00:00

abstract：:Many published studies have evaluated the association between the 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) polymorphism and the risk of congenital heart disease (CHD); however, the specific conclusion is still controversial.To get a more accurate conclusion, we used a meta-analysis to evaluat...

journal_title：International heart journal

authors： Liu PF,Ding B,Zhang JY,Mei XF,Li F,Wu P,Mei CH,Zhou YF,Chen T

更新日期：2020-05-30 00:00:00

abstract：:Several recent studies have suggested that arterial stiffness parameters such as peripheral pulse pressure (PPP), central blood pressure (CBP), and pulse wave velocity (PWV) are more accurate markers than brachial blood pressure for prediction of cardiovascular (CV) events. However, it remains unknown which arterial s...

journal_title：International heart journal

authors： Ishisone T,Koeda Y,Tanaka F,Sato K,Nagano M,Nakamura M

更新日期：2013-01-01 00:00:00

abstract：:Tenascin-C (TNC) is involved in aortic disease pathophysiology. This study aims to evaluate TNC's value for predicting in-hospital death in acute aortic dissection (AD).We prospectively enrolled consecutive patients with suspected acute AD within 48 hours from symptom onset. Serum TNC and C-reactive protein (CRP) leve...

journal_title：International heart journal

authors： Guo T,Zhou X,Zhu A,Peng W,Zhong Y,Chai X

更新日期：2019-07-27 00:00:00