Platelet-derived growth factor receptor-tyrosine kinase inhibitor, imatinib, is effective for treating pulmonary hypertension induced by pulmonary tumor thrombotic microangiopathy.

abstract：:Worsening of mitral regurgitation (MR) is sometimes observed after closure of an atrial septal defect (ASD). However, since the mechanism of this deterioration remains unclear, the aim of our study was to investigate the effect of left (LV) and right ventricular (RV) geometry on MR after transcatheter closure of ASD.W...

journal_title：International heart journal

authors： Hiraishi M,Tanaka H,Motoji Y,Sawa T,Tsuji T,Miyoshi T,Imanishi J,Kaneko A,Matsumoto K,Shinke T,Hirata K

更新日期：2015-01-01 00:00:00

abstract：:Multivessel disease (MVD) is an independent risk factor for poor prognosis in acute myocardial infarction patients. Although several global risk scoring systems (RSS) are in use in clinical practice, there is no dedicated RSS for MVD in ST-segment elevation myocardial infarction (STEMI). The primary objective of this ...

journal_title：International heart journal

authors： Ryu KS,Bae JW,Jeong MH,Cho MC,Ryu KH,and other Korea Acute Myocardial Infarction Registry Investigators.

更新日期：2019-05-30 00:00:00

abstract：:The aim of the present study was to determine if there is any association between white coat hypertension (WCH) and body mass index. The study was performed in two phases. In the first phase, we studied consecutive underweight patients, while in the second phase, age-matched consecutive normal weight, overweight, and ...

journal_title：International heart journal

authors： Helvaci MR,Kaya H,Yalcin A,Kuvandik G

更新日期：2007-09-01 00:00:00

abstract：:Apelin was proved to attenuate cardiac interstitial fibrosis. However, the association between apelin level and myocardial fibrosis in patients with hypertrophic cardiomyopathy (HCM) is still unclear.This study aims to determine whether apelin is associated with myocardial fibrosis in HCM and investigate the predictiv...

journal_title：International heart journal

authors： Zhou Y,Yuan J,Wang Y,Qiao S

更新日期：2019-05-30 00:00:00

abstract：:Purulent pericarditis is a rare disease in the antibiotic era. The common pathogens of purulent pericarditis are gram-positive species such as Staphylococcus aureus. Streptococcus pneumoniae, Salmonella, Haemophilus, fungal pathogens/tuberculosis can also result in purulent pericarditis. We report an old male case of ...

journal_title：International heart journal

authors： Horii S,Yada H,Ito K,Osaki A,Sato A,Kimura T,Yasuda R,Toya T,Namba T,Masaki N,Adachi T

更新日期：2018-05-30 00:00:00

abstract：:We are pleased to announce that the following 4 articles have been selected for the the UEDA Heart Awards for the Year 2016.First PlaceDelivery of Imatinib-Incorporated Nanoparticles into Lungs Suppresses the Development of Monocrotaline-Induced Pulmonary Arterial HypertensionSatoshi Akagi, Kazufumi Nakamura, Daiji Mi...

journal_title：International heart journal

authors：

更新日期：2016-01-01 00:00:00

abstract：:Statins provide effective secondary prevention of cardiovascular events after acute coronary syndrome (ACS). Current guidelines recommend that statins be initiated in ACS patients before hospital discharge. In this retrospective study, we investigated the influence of early compared with late in-hospital initiation of...

journal_title：International heart journal

authors： Li YH,Wu HL,Yang YH,Tsai HS,Chao TH

更新日期：2007-11-01 00:00:00

abstract：:Changes in the expression levels of several genes have been described in aortic aneurysm specimens, however, the spectrum of diverse molecular alterations remains to be elucidated. We attempted to identify key molecules that modulate the pathogenesis of aortic aneurysm, using a complimentary DNA microarray carrying ap...

journal_title：International heart journal

authors： Taketani T,Imai Y,Morota T,Maemura K,Morita H,Hayashi D,Yamazaki T,Nagai R,Takamoto S

更新日期：2005-03-01 00:00:00

abstract：:This experimental study investigated the impact of hyperglycemic control on left ventricular (LV) function using a model of diabetes mellitus (DM) (induced by streptozocin 60 mg/kg). Sixteen adult-Sprague Dawley rats were divided into group 1 (poor hyperglycemic control, n = 8) and group 2 (good hyperglycemic control,...

journal_title：International heart journal

authors： Sung PH,Sun CK,Ko SF,Chang LT,Sheu JJ,Lee FY,Wu CJ,Chua S,Yip HK

更新日期：2009-03-01 00:00:00

abstract：:This study aimed to evaluate the clinical characteristics and surgical treatment of bicuspid aortic valve (BAV) infective endocarditis (IE) compared with tricuspid aortic valve (TAV) IE in China.The relevant pre-, intra- and post-operative materials of all IE patients undergoing cardiac surgery in our center between J...

journal_title：International heart journal

authors： Chen J,Lu S,Hu K,Yang Z,Pan S,Hong T,Wang C

更新日期：2017-04-06 00:00:00

abstract：:Left ventricular outflow tract obstruction (LVOTO) is commonly observed in patients with hypertrophic cardiomyopathy (HCM) or left ventricular hypertrophy (LVH). While some patients develop LVOTO at rest, it can also be provoked by physical exertion, and hence termed latent LVOTO (L-LVOTO). Recent reports demonstrated...

journal_title：International heart journal

authors： Semba H,Sawada H,Uejima T,Takeda N,Soma K,Abe H,Yamashita T,Nagai R

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To follow-up and estimate cardiac function in 11 heart failure patients with moderate to severe mitral regurgitation who underwent cardiac resynchronization therapy (CRT) and to compare echocardiography to the rebreathing method (indirect Fick method) which were used for estimation. DESIGN:Prospective, obser...

journal_title：International heart journal

authors： Dong L,Wang JA,Yang Q,He H,Sun Y,Chen DD

更新日期：2007-01-01 00:00:00

abstract：:While physiological levels of nitric oxide (NO) protect the endothelium and have vasodilatory effects, excessive NO has adverse effects on the cardiovascular system. Recently, new NO-releasing pharmacodynamic hybrids of angiotensin II (Ang II) type 1 (AT1) receptor blockers (ARBs) have been developed.We analyzed wheth...

journal_title：International heart journal

authors： Yahiro E,Miura S,Suematsu Y,Matsuo Y,Arimura T,Kuwano T,Imaizumi S,Iwata A,Uehara Y,Saku K

更新日期：2015-01-01 00:00:00

abstract：:A 27-year-old woman, who had received mitral valve repair for mitral regurgitation resulting from infective endocarditis, was admitted for a close examination of abnormal echocardiographic findings in the left atrium. Transthoracic echocardiography showed trivial mitral regurgitation with normal left ventricular contr...

journal_title：International heart journal

authors： Aoyagi S,Fukunaga S,Ishihara K,Egawa N,Hosokawa Y,Nakamura E

更新日期：2006-01-01 00:00:00

abstract：:To investigate parameters which were related with long-term mortality in patients hospitalized for acute heart failure (AHF).A total of 287 patients with AHF presenting to the First Affiliated Hospital of Nanjing Medical University were enrolled into the registry from April 2012 to January 2015. The primary endpoint w...

journal_title：International heart journal

authors： Jin M,Wei S,Gao R,Wang K,Xu X,Yao W,Zhang H,Zhou Y,Xu D,Zhou F,Li X

更新日期：2017-05-31 00:00:00

abstract：:Electrocardiography (ECG) is used to screen for pulmonary hypertension (PH). However, it is unclear which parameters of ECG are the most useful for screening.ECG parameters related to right ventricular hypertrophy criteria were examined in 145 ECGs of subjects who were suspected to have PH and underwent right heart ca...

journal_title：International heart journal

authors： Miura M,Ikeda S,Yoshida T,Yamagata Y,Nakata T,Koga S,Koide Y,Kawano H,Maemura K

更新日期：2018-01-27 00:00:00

abstract：:Despite its clinical relevance, a subclass of acute decompensated heart failure (ADHF) with elevated blood pressure, known as hypertensive ADHF (HT-ADHF), has been less intensively evaluated. This study aimed to characterize the prognostic nature and pathophysiology of HT-ADHF. A total of 509 consecutive patients with...

journal_title：International heart journal

authors： Hiki M,Iwata H,Takasu K,Nojiri S,Ishikawa G,Chikata Y,C Mattson P,Kasai T,Miyazaki T,Inoue K,Fujiwara Y,Sumiyoshi M,Kinugawa K,Daida H

更新日期：2020-03-28 00:00:00

abstract：:A 68-year-old female with acute coronary syndrome was transferred to our hospital. Emergency coronary angiography showed 90% stenosis with severe calcification in the proximal right coronary artery (RCA). Intravascular ultrasound (IVUS) images were obtained and showed circumferential heavy calcification without any ev...

journal_title：International heart journal

authors： Goryo Y,Kume T,Kobayashi Y,Okamoto H,Kawamura A,Fukuhara K,Koyama T,Yamada R,Imai K,Neishi Y,Uemura S

更新日期：2017-02-07 00:00:00

abstract：:Marfan syndrome (MFS) is a systemic connective tissue disorder that is caused by mutations of fibrillin-1. While MFS patients are at a high risk of periodontitis and aortic diseases, little causal information has been provided to date. To clarify the relationship, their oral condition and sinus of Valsalva (SoV) were ...

journal_title：International heart journal

authors： Suzuki J,Imai Y,Aoki M,Fujita D,Takeda N,Aoyama N,Wakayama K,Ikeda Y,Kumagai H,Akazawa H,Izumi Y,Isobe M,Komuro I,Hirata Y

更新日期：2016-07-27 00:00:00

abstract：:Sarcoidosis is a systemic granulomatous disorder whose prognosis worsens when the heart is involved, and early diagnosis is important. Endomyocardial biopsy is the most helpful diagnostic examination, but suffers from low sensitivity and low specificity. Microvolt T wave alternans (MVTWA) is utilized in noninvasive ex...

journal_title：International heart journal

authors： Matsumoto S,Hirayama Y,Saitoh H,Ino T,Miyauchi Y,Iwasaki YK,Yasutake M,Seino Y,Atarashi H,Katoh T,Mizuno K

更新日期：2009-11-01 00:00:00

abstract：:The significance of pulse pressure (PP) and mean blood pressure (MBP) for blood pressure (BP) control is unclear. The aim of this study was to examine the relationship between PP and MBP and BP control. We obtained home BP measurements for 117 patients aged 40-75 years with either office systolic BP (SBP) >or= 140 mmH...

journal_title：International heart journal

authors： Yoshitomi Y,Nagakura C,Miyauchi A

更新日期：2005-07-01 00:00:00

abstract：:Mitral and aortic valve regurgitation is commonly found in osteogenesis imperfecta (OI) patients, however, little is known about the myocardial involvement in this disorder. An 82-year-old man with OI developed heart failure and was admitted to our hospital. Echocardiogram revealed severe mitral regurgitation without ...

journal_title：International heart journal

authors： Soma K,Abe H,Takeda N,Shintani Y,Takazawa Y,Kojima T,Fujiu K,Semba H,Yamashita H,Hirata Y,Fukayama M,Nagai R

更新日期：2012-01-01 00:00:00

abstract：:Activation of mineralocorticoid receptor (MR) is shown in resistant hypertension including diabetes mellitus. Although protein kinase C (PKC) signaling is involved in the pathogenesis of diabetic complications, an association between PKC and MR is not known. Activation of PKCα and PKCβ by TPA (12-O-Tetradecanoylphorbo...

journal_title：International heart journal

authors： Hayashi T,Shibata H,Kurihara I,Yokota K,Mitsuishi Y,Ohashi K,Murai-Takeda A,Jo R,Ohyama T,Sakamoto M,Tojo K,Tajima N,Utsunomiya K,Itoh H

更新日期：2017-10-21 00:00:00

abstract：:The aim of this study was to investigate whether electrical stimulation of skeletal muscles could represent a rehabilitation alternative for patients with chronic heart failure (CHF). Thirty patients with CHF and NYHA class II-III were randomly assigned to a rehabilitation program using either electrical stimulation o...

journal_title：International heart journal

authors： Dobsák P,Nováková M,Fiser B,Siegelová J,Balcárková P,Spinarová L,Vítovec J,Minami N,Nagasaka M,Kohzuki M,Yambe T,Imachi K,Nitta S,Eicher JC,Wolf JE

更新日期：2006-05-01 00:00:00

abstract：:A prospective observational study was conducted to evaluate the predictive value of interleukin-18 (IL-18) for major adverse cardiovascular events (MACEs) in hemodialysis patients. A total of 85 participants (45 hemodialysis patients and 40 healthy volunteers) with a mean age of 56.3 years were enrolled in this study....

journal_title：International heart journal

authors： Wang S,Chen F,Yang S,Shi J

更新日期：2018-07-31 00:00:00

abstract：:Epicardial adipose tissue (EAT) is presumed to play an important role in the development of coronary artery disease (CAD). The purpose of our study was to examine the influence of EAT volume measured by cardiac CT on the severity and presence of CAD. A total of 209 subjects (114 normal subjects and 95 patients with CA...

journal_title：International heart journal

authors： Kim SH,Chung JH,Kwon BJ,Song SW,Choi WS

更新日期：2014-01-01 00:00:00

abstract：:Transradial percutaneous coronary intervention (PCI), which is less invasive than transfemoral PCI, may facilitate early rehabilitation of patients with acute myocardial infarction (AMI). The aim of our study was to investigate whether transradial PCI is associated with a shorter coronary care unit (CCU) stay in very ...

journal_title：International heart journal

authors： Jinnouchi H,Sakakura K,Wada H,Kubo N,Sugawara Y,Nakamura T,Funayama H,Ako J,Momomura S

更新日期：2012-01-01 00:00:00

abstract：:There are many published articles on the effects of the antithrombolytic function of platelet glycoprotein IIb/IIIa inhibitors (GP IIb/IIIa inhibitors) in myocardial infarction. However, few studies have explored the effects and optimal concentration of tirofibans in diminishing the extent of myocardial reperfusion in...

journal_title：International heart journal

authors： Chang ST,Chung CM,Chu CM,Yang TY,Pan KL,Hsu JT,Hsiao JF

更新日期：2015-05-13 00:00:00

abstract：:The metabolism of branched-chain amino acids (BCAAs) is reported to change in heart failure (HF) and correlate with cardiac function. However, the effect of BCAAs on HF remains controversial. We investigate the prognostic value of the plasma BCAA level in nonischemic dilated cardiomyopathy (NIDCM).This study enrolled ...

journal_title：International heart journal

authors： Kimura Y,Okumura T,Kazama S,Shibata N,Oishi H,Arao Y,Kuwayama T,Kato H,Yamaguchi S,Hiraiwa H,Kondo T,Morimoto R,Murohara T

更新日期：2020-07-30 00:00:00

abstract：:Prostaglandin F(2alpha) (PGF(2alpha)) stimulates hypertrophic growth of neonatal rat cardiac myocytes, a feature of which includes downregulation of the Ca(2+)-ATPase (SERCA2), a major Ca(2+) transport protein in SR. The molecular mechanisms by which PGF(2alpha) inhibits SERCA2 gene expression remain unknown. We deter...

journal_title：International heart journal

authors： Hara S,Arai M,Tomaru K,Doi H,Koitabashi N,Iso T,Watanabe A,Tanaka T,Maeno T,Suga T,Yokoyama T,Kurabayashi M

更新日期：2008-05-01 00:00:00