Prostaglandin F2alpha inhibits SERCA2 gene transcription through an induction of Egr-1 in cultured neonatal rat cardiac myocytes.

abstract：:Infective endocarditis (IE) caused by Serratia liquefaciens has been reported in only 2 adults. We experienced the first pediatric (neonatal) case of IE caused by S. liquefaciens, with mitral valve vegetation 4 days after a palliative heart surgery. This report underscores the importance of treating for both gram-posi...

journal_title：International heart journal

authors： Momose T,Masutani S,Oshima A,Kawasaki H,Tanaka R,Iwamoto Y,Ishido H,Senzaki H

更新日期：2018-11-28 00:00:00

abstract：:We present a 16-year-old male patient with hypoplastic left heart syndrome who developed protein-losing enteropathy (PLE) and plastic bronchitis (PB) after a Fontan operation. He received medical therapies, including albumin infusion, unfractionated heparin, and high-dose anti-aldosterone therapy but could not obtain ...

journal_title：International heart journal

authors： Okada S,Muneuchi J,Nagatomo Y,Nonaka K,Iida C,Shirouzu H,Matsuoka R,Watanabe M,Joo K

更新日期：2018-07-31 00:00:00

abstract：OBJECTIVE:To follow-up and estimate cardiac function in 11 heart failure patients with moderate to severe mitral regurgitation who underwent cardiac resynchronization therapy (CRT) and to compare echocardiography to the rebreathing method (indirect Fick method) which were used for estimation. DESIGN:Prospective, obser...

journal_title：International heart journal

authors： Dong L,Wang JA,Yang Q,He H,Sun Y,Chen DD

更新日期：2007-01-01 00:00:00

abstract：:This study tested the hypothesis that activated toll-like receptor-4 (TLR-4) is closely related to combined major adverse clinical outcomes (MACO) [defined as advanced Killip score (> or = 3), overt congestive heart failure (CHF) (New York Heart Association functional class > or = 2) or 30-day death] in patients with ...

journal_title：International heart journal

authors： Sheu JJ,Chang LT,Chiang CH,Youssef AA,Wu CJ,Lee FY,Yip HK

更新日期：2008-01-01 00:00:00

abstract：:To investigate parameters which were related with long-term mortality in patients hospitalized for acute heart failure (AHF).A total of 287 patients with AHF presenting to the First Affiliated Hospital of Nanjing Medical University were enrolled into the registry from April 2012 to January 2015. The primary endpoint w...

journal_title：International heart journal

authors： Jin M,Wei S,Gao R,Wang K,Xu X,Yao W,Zhang H,Zhou Y,Xu D,Zhou F,Li X

更新日期：2017-05-31 00:00:00

abstract：:Marfan syndrome (MFS) is an inherited connective tissue disorder mainly caused by the fibrillin-1 mutation. Deficient fibrillin-1 is thought to result in the failed sequestration of transforming growth factor β (TGFβ) and subsequent activation of the TGFβ signaling pathway, suggesting that the circulating TGFβ level m...

journal_title：International heart journal

authors： Ogawa N,Imai Y,Nishimura H,Kato M,Takeda N,Nawata K,Taketani T,Morota T,Takamoto S,Nagai R,Hirata Y

更新日期：2013-01-01 00:00:00

abstract：:Most previous studies have examined the effects of antihypertensive drugs in hypertensive animals for only a few months, and little information has been provided as to the protective effects of lifetime antihypertensive medication against cardiovascular organ injury. In this study, spontaneously hypertensive rats (SHR...

journal_title：International heart journal

authors： Ishimitsu T,Honda T,Ohno E,Furukata S,Sudo Y,Nakano N,Takahashi T,Ono H,Matsuoka H

更新日期：2010-01-01 00:00:00

abstract：:Sirt1 is a highly conserved nicotinamide adenine dinucleotide (NAD(+)) dependent histone deacetylase which plays an important role in heart diseases. Studies performed with Sirt1 activators indicated that it protects cells from ischemia/ reperfusion (I/R) injury. The protective effects of H2S against I/R injury also h...

journal_title：International heart journal

authors： Hu MZ,Zhou B,Mao HY,Sheng Q,Du B,Chen JL,Pang QF,Ji Y

更新日期：2016-07-27 00:00:00

abstract：:Several studies have reported that the left ventricular (LV) lead implant success rate ranges between 88.0% and 92.4%. Coronary venous anatomy differs among patients thus, necessitating multiple types of leads. To date, the implant success rate among Japanese patients utilizing a pre-specified family LV leads (includi...

journal_title：International heart journal

authors： Ando K,Kanda S,Miura F,Ashikaga K,Ehara N,Sakai Y,Furukawa T,Yoshimura H,Adachi K

更新日期：2018-09-26 00:00:00

abstract：:The significance of pulse pressure (PP) and mean blood pressure (MBP) for blood pressure (BP) control is unclear. The aim of this study was to examine the relationship between PP and MBP and BP control. We obtained home BP measurements for 117 patients aged 40-75 years with either office systolic BP (SBP) >or= 140 mmH...

journal_title：International heart journal

authors： Yoshitomi Y,Nagakura C,Miyauchi A

更新日期：2005-07-01 00:00:00

abstract：:Exhaled acetone concentration is one of the expected compounds to be a breath biomarker in heart failure. However, it has not been clarified how exhaled acetone concentration changes in clinical course of heart failure.To investigate whether exhaled acetone concentration changes after treatment in acute decompensated ...

journal_title：International heart journal

authors： Yokokawa T,Sato T,Suzuki S,Oikawa M,Yoshihisa A,Kobayashi A,Yamaki T,Kunii H,Nakazato K,Suzuki H,Saitoh SI,Ishida T,Shimouchi A,Takeishi Y

更新日期：2018-07-31 00:00:00

abstract：:Although pressure-overload right ventricular hypertrophy is a long-term risk in some congenital heart diseases such as tetralogy of Fallot, how it develops is unclear. The aim of this study was to investigate the mechanism of development of this right ventricular heart failure.Pulmonary artery banding in 10-day-old ra...

journal_title：International heart journal

authors： Minegishi S,Kitahori K,Murakami A,Ono M

更新日期：2011-01-01 00:00:00

abstract：:The objective of the present prospective multicenter case-control study was to investigate the long-term clinical outcome (5 years) of primary stenting compared to primary percutaneous transluminal coronary angioplasty (PTCA) without stenting (POBA) in patients with acute myocardial infarction at 7 cardiovascular cent...

journal_title：International heart journal

authors： Sasao H,Tsuchihashi K,Nagao K,Miyamoto K,Murakami H,Doi A,Shimoshige S,Hasegawa K,Kyuma M,Noda R,Shimamoto K

更新日期：2006-01-01 00:00:00

abstract：:Elderly people represent the fastest growing portion of cardiovascular patients. We aimed to analyze the clinical presentation, risk factors, co-morbidities, complications, and mortality in patients 90 years or more who underwent coronary angiography and intervention.We retrospectively studied 108 (0.25% of 43,385) co...

journal_title：International heart journal

authors： Gayed M,Yadak N,Qamhia W,Daralammouri Y,Ohlow MA

更新日期：2017-04-06 00:00:00

abstract：:Uninterrupted anticoagulation therapy during atrial fibrillation (AF) ablation minimizes the risk of periprocedural thromboembolic events. Although the use of direct oral anticoagulants (DOACs) has rapidly developed in patients undergoing AF ablation, no antidote is available for factor Xa inhibitors. We sought to inv...

journal_title：International heart journal

authors： Aoyama D,Miyazaki S,Hasegawa K,Kaseno K,Ishikawa E,Mukai M,Miyahara K,Aiki T,Matsui A,Yamaguchi J,Shiomi Y,Tama N,Ikeda H,Fukuoka Y,Morishita T,Ishida K,Uzui H,Tada H

更新日期：2019-11-30 00:00:00

abstract：:Despite its clinical relevance, a subclass of acute decompensated heart failure (ADHF) with elevated blood pressure, known as hypertensive ADHF (HT-ADHF), has been less intensively evaluated. This study aimed to characterize the prognostic nature and pathophysiology of HT-ADHF. A total of 509 consecutive patients with...

journal_title：International heart journal

authors： Hiki M,Iwata H,Takasu K,Nojiri S,Ishikawa G,Chikata Y,C Mattson P,Kasai T,Miyazaki T,Inoue K,Fujiwara Y,Sumiyoshi M,Kinugawa K,Daida H

更新日期：2020-03-28 00:00:00

abstract：:The efficacy of heart failure (HF) management programs is compromised by the challenge of early identification of patients at imminent risk. Segmental multifrequency bioelectrical impedance analysis can generate an "edema index" (EI) as a surrogate for the body fluid status. In this study, we tested whether integratio...

journal_title：International heart journal

authors： Liu MH,Wang CH,Huang YY,Tung TH,Lee CM,Yang NI,Wang JS,Kuo LT,Cherng WJ

更新日期：2012-01-01 00:00:00

abstract：:Apelin was proved to attenuate cardiac interstitial fibrosis. However, the association between apelin level and myocardial fibrosis in patients with hypertrophic cardiomyopathy (HCM) is still unclear.This study aims to determine whether apelin is associated with myocardial fibrosis in HCM and investigate the predictiv...

journal_title：International heart journal

authors： Zhou Y,Yuan J,Wang Y,Qiao S

更新日期：2019-05-30 00:00:00

abstract：:Changes in the expression levels of several genes have been described in aortic aneurysm specimens, however, the spectrum of diverse molecular alterations remains to be elucidated. We attempted to identify key molecules that modulate the pathogenesis of aortic aneurysm, using a complimentary DNA microarray carrying ap...

journal_title：International heart journal

authors： Taketani T,Imai Y,Morota T,Maemura K,Morita H,Hayashi D,Yamazaki T,Nagai R,Takamoto S

更新日期：2005-03-01 00:00:00

abstract：:Coronary collateral circulation (CCC) plays a crucial role in myocardial blood supply, especially for ischemic myocardium. Previous study has shown that neuregulin-1 is a prominent angiogenic factor in diabetic cardiomyopathy, whereas the relationship between neuregulin-1 and CCC has not been investigated. Thus, we ai...

journal_title：International heart journal

authors： Huang M,Zheng J,Chen Z,You C,Huang Q

更新日期：2020-01-31 00:00:00

abstract：:Ablation catheters with multiple electrodes are effective for the creation of linear atrial lesions but are associated with an increased risk of coagulum formation. In an animal study, we used a novel 9Fr deflectable ablation catheter with two saline/foam electrode pocket covered with 20 mm tubing. Each pocket contain...

journal_title：International heart journal

authors： Watanabe I,Min N,Okumura Y,Kofune M,Ashino S,Ohkubo K,Nakai T,Kunimoto S,Kasamaki Y,Hirayama A

更新日期：2009-05-01 00:00:00

abstract：:Prognosis of patients with heart failure (HF) remains unclear in Japan and should be determined in a prospective fashion. A prospective cohort of The Shinken Database comprised details on all of the new patients, including both inpatients and outpatients, who visited The Cardiovascular Institute Hospital in 2004-2005....

journal_title：International heart journal

authors： Goda A,Yamashita T,Suzuki S,Ohtsuka T,Uejima T,Oikawa Y,Yajima J,Koike A,Nagashima K,Kirigaya H,Sagara K,Ogasawara K,Isobe M,Sawada H,Aizawa T

更新日期：2009-09-01 00:00:00

abstract：:Adaptive servo-ventilation (ASV) is a recently-developed non-invasive therapy that improves the clinical course of heart failure (HF) patients. However, the precise hemodynamic response and predictors of ASV therapy remain uncertain. Overall, 69 patients with New York Heart Association HF class II-IV underwent 10-minu...

journal_title：International heart journal

authors： Imamura T,Kinugawa K

更新日期：2017-08-03 00:00:00

abstract：:Previous studies reporting that statin increases coronary artery calcium (CAC) were conducted exclusively on patients with statin as a prevention, regardless of the presence or absence of dyslipidemia. The impact of sex on CAC has not been fully evaluated. We aimed to determine the association of dyslipidemia and sex ...

journal_title：International heart journal

authors： Asami M,Yamaji K,Aoki J,Tanimoto S,Watanabe M,Horiuchi Y,Furui K,Kato N,Hara K,Tanabe K

更新日期：2017-10-21 00:00:00

abstract：:A prospective observational study was conducted to evaluate the predictive value of interleukin-18 (IL-18) for major adverse cardiovascular events (MACEs) in hemodialysis patients. A total of 85 participants (45 hemodialysis patients and 40 healthy volunteers) with a mean age of 56.3 years were enrolled in this study....

journal_title：International heart journal

authors： Wang S,Chen F,Yang S,Shi J

更新日期：2018-07-31 00:00:00

abstract：:The long-term prognosis for up to 20 years of patients who have undergone percutaneous transvenous mitral commissurotomy (PTMC) for mitral stenosis (MS) is unknown.We examined 77 of 93 patients (83%) with MS and who underwent PTMC from 1989 to 2002 at our institute, as well as the occurrence of either one of the follo...

journal_title：International heart journal

authors： Kubota N,Ozaki K,Hoyano M,Nishida K,Takano T,Okubo T,Kimura S,Yanagawa T,Kashimura T,Minamino T

更新日期：2020-11-28 00:00:00

abstract：:An aorto-cutaneous fistula is a rare complication that occurs after aortic surgery. Due to its rarity, postoperative complications are not normally highlighted in most standard teaching. We report here a case of aorto-cutaneous fistula after surgical treatment of a Stanford type A aortic dissection (AD) in a 67-year-o...

journal_title：International heart journal

authors： Zhao C,Zhu Z,Zheng X,Liu K

更新日期：2018-01-27 00:00:00

abstract：:Multivessel disease (MVD) is an independent risk factor for poor prognosis in acute myocardial infarction patients. Although several global risk scoring systems (RSS) are in use in clinical practice, there is no dedicated RSS for MVD in ST-segment elevation myocardial infarction (STEMI). The primary objective of this ...

journal_title：International heart journal

authors： Ryu KS,Bae JW,Jeong MH,Cho MC,Ryu KH,and other Korea Acute Myocardial Infarction Registry Investigators.

更新日期：2019-05-30 00:00:00

abstract：:Atherosclerosis is a multifactorial vascular disease characterized by formation of inflammatory lesions. Secretory phospholipase A2, group IIA (sPLA2-IIA) is involved in this process and plays a critical role. However, the exact role of sPLA2-IIA in cardiovascular inflammation is more complicated and remains unclear. ...

journal_title：International heart journal

authors： Xie Q,Zhang D

更新日期：2017-02-07 00:00:00

abstract：:The progression of heart failure with reduced ejection fraction is promoted by sympathovagal imbalance. Baroreflex activation therapy (BAT) by the electrical stimulation of baroreceptors at the carotid sinus significantly improved exercise capacity and NT-proBNP levels in a randomized trial; however, no significant di...

journal_title：International heart journal

authors： Halbach M,Fritz T,Madershahian N,Pfister R,Reuter H

更新日期：2017-12-12 00:00:00