Effect of early versus late in-hospital initiation of statin therapy on the clinical outcomes of patients with acute coronary syndrome.

abstract：:Coronary heart disease (CHD) is recognized as a lifestyle-related disease and is the second leading cause of death in Japan. However, the cardiac risk factor profile of young patients with CHD has not been clarified in suburban areas of Japan. Our study aimed to determine metabolic and lifestyle risk factors in young ...

journal_title：International heart journal

authors： Azegami M,Hongo M,Yanagisawa S,Yamazaki A,Sakaguchi K,Yazaki Y,Imamura H

更新日期：2006-05-01 00:00:00

abstract：:Proinflammatory cytokine responses might occur in elderly individuals with cardiovascular (CV) disease, cerebro-vascular (CVA) disease, and/or pulmonary disease (PD). Spiritual activation is an important coping mechanism, since psychiatric depression is an important risk factor for these individuals. Thirty-three very...

journal_title：International heart journal

authors： Kurita A,Takase B,Shinagawa N,Kodani E,Okada K,Iwahara S,Kusama Y,Atarashi H

更新日期：2011-01-01 00:00:00

abstract：:The aim of the present study was to determine whether symptoms of atrial fibrillation (AF) differ between patients with and without subsequent permanent AF. Sixty-four patients (68 +/- 10 years old, 45 males) were recruited. AF follow-up was started at the age of 61 +/- 10 years and accomplished in a median period of ...

journal_title：International heart journal

authors： Kawara T,Narumi J,Hirao K,Kasuya K,Kawabata M,Tojo N,Isobe M,Matsuura M

更新日期：2010-07-01 00:00:00

abstract：:Impaired oxygenation sometimes occurs in patients with acute aortic dissection, however, the mechanism has not been fully investigated. We hypothesized that impaired oxygenation is related to inflammation secondary due to aortic dissection. Patients with acute aortic dissection who had received 14 days of conservative...

journal_title：International heart journal

authors： Komukai K,Shibata T,Mochizuki S

更新日期：2005-09-01 00:00:00

abstract：:Several studies have revealed that stress after catastrophic disasters can trigger cardiovascular events, however, little is known about its association with the occurrence of heart failure in past earthquakes. The objective of the present study was to determine whether the Great East Japan Earthquake on March 11, 201...

journal_title：International heart journal

authors： Suzuki H,Yamada S,Kamiyama Y,Takeishi Y

更新日期：2014-01-01 00:00:00

abstract：:To investigate parameters which were related with long-term mortality in patients hospitalized for acute heart failure (AHF).A total of 287 patients with AHF presenting to the First Affiliated Hospital of Nanjing Medical University were enrolled into the registry from April 2012 to January 2015. The primary endpoint w...

journal_title：International heart journal

authors： Jin M,Wei S,Gao R,Wang K,Xu X,Yao W,Zhang H,Zhou Y,Xu D,Zhou F,Li X

更新日期：2017-05-31 00:00:00

abstract：:Our previous study showed that pravastatin prevents ischemia and reperfusion-induced lethal ventricular fibrillation in rats. This study explored whether pravastatin decreases myocardial infarct size and this effect is associated with endothelial nitric oxide synthase (eNOS) expression in myocardium. Rats were treated...

journal_title：International heart journal

authors： Li H,Wang C,Sun J,Liu C,Li N,Chen J

更新日期：2018-01-01 00:00:00

abstract：:The long-term prognosis for up to 20 years of patients who have undergone percutaneous transvenous mitral commissurotomy (PTMC) for mitral stenosis (MS) is unknown.We examined 77 of 93 patients (83%) with MS and who underwent PTMC from 1989 to 2002 at our institute, as well as the occurrence of either one of the follo...

journal_title：International heart journal

authors： Kubota N,Ozaki K,Hoyano M,Nishida K,Takano T,Okubo T,Kimura S,Yanagawa T,Kashimura T,Minamino T

更新日期：2020-11-28 00:00:00

abstract：:Uninterrupted anticoagulation therapy during atrial fibrillation (AF) ablation minimizes the risk of periprocedural thromboembolic events. Although the use of direct oral anticoagulants (DOACs) has rapidly developed in patients undergoing AF ablation, no antidote is available for factor Xa inhibitors. We sought to inv...

journal_title：International heart journal

authors： Aoyama D,Miyazaki S,Hasegawa K,Kaseno K,Ishikawa E,Mukai M,Miyahara K,Aiki T,Matsui A,Yamaguchi J,Shiomi Y,Tama N,Ikeda H,Fukuoka Y,Morishita T,Ishida K,Uzui H,Tada H

更新日期：2019-11-30 00:00:00

abstract：:Tenascin-C (TNC) is involved in aortic disease pathophysiology. This study aims to evaluate TNC's value for predicting in-hospital death in acute aortic dissection (AD).We prospectively enrolled consecutive patients with suspected acute AD within 48 hours from symptom onset. Serum TNC and C-reactive protein (CRP) leve...

journal_title：International heart journal

authors： Guo T,Zhou X,Zhu A,Peng W,Zhong Y,Chai X

更新日期：2019-07-27 00:00:00

abstract：:Percutaneous coronary intervention for the treatment of a severe calcified lesion is still one of the most technically challenging areas of interventional cardiology. Calcified lesions are a cause of stent underexpansion, which significantly increases the subsequent risks of in-stent restenosis and thrombosis, even wh...

journal_title：International heart journal

authors： Otsuka Y,Koyama T,Imoto Y,Katsuki Y,Kawahara M,Nakamura K,Kodama S,Noguchi H,Iwasaki K

更新日期：2017-12-12 00:00:00

abstract：:To investigate the combination of high-sensitivity C-reactive protein (hs-CRP) and Low-density lipoprotein (LDL)-C as the targets for statin treatment in patients with acute coronary syndrome (ACS). This single-center, prospective, randomized study was performed in 400 patients treated with atorvastatin 40 mg/day for ...

journal_title：International heart journal

authors： Fang M,Qian Q,Zhao Z,Zhu L,Su J,Li X

更新日期：2018-03-30 00:00:00

abstract：:The purpose of this study was to examine the relation between adiponectin levels and subclinical carotid atherosclerosis in patients undergoing coronary artery bypass grafting (CABG). Serum concentrations of adiponectin and carotid intima/media thickness (IMT) were measured in 84 consecutive patients who underwent CAB...

journal_title：International heart journal

authors： Kiris I,Tekin I,Yesildag A,Vural H,Oyar O,Sirin B,Okutan H,Ibrisim E

更新日期：2006-11-01 00:00:00

abstract：:Sirt1 is a highly conserved nicotinamide adenine dinucleotide (NAD(+)) dependent histone deacetylase which plays an important role in heart diseases. Studies performed with Sirt1 activators indicated that it protects cells from ischemia/ reperfusion (I/R) injury. The protective effects of H2S against I/R injury also h...

journal_title：International heart journal

authors： Hu MZ,Zhou B,Mao HY,Sheng Q,Du B,Chen JL,Pang QF,Ji Y

更新日期：2016-07-27 00:00:00

abstract：:Mechanical heart valve replacement (MHVR) entails lifetime oral anticoagulation to eliminate thrombosis. However, adverse events may still occur despite proper anticoagulation therapy. In this study, we investigated whether D-dimer can predict the clinical events in post-MHVR patients during oral anticoagulation thera...

journal_title：International heart journal

authors： Zhang L,Long Y,Xiao H,Yang J,Liu X,Zhang Z

更新日期：2019-05-30 00:00:00

abstract：:Flexible, in vivo maneuverable electrophysiology mapping techniques are not available in rat models. A novel cardiac stereotactic electrophysiology epicardial mapping system (CREAMS) allows for various measurements, including: (1) recording unipolar electrograms at multiple sites; (2) positioning of mapped sites and p...

journal_title：International heart journal

authors： Fan B,Wang H,Wu T,Li Y,Lin Z,Li M,Li Q,Zhang W,Zheng Q

更新日期：2019-03-20 00:00:00

abstract：:Plaque erosion (PE) is a significant substrate of acute coronary thrombosis. An improved ability to distinguish plaque phenotype in vivo among patients with ST-segment elevation myocardial infarction (STEMI) is of considerable interest because of the potential to formulate tailored treatment. This study assessed the p...

journal_title：International heart journal

authors： Dong H,Hu S,Sun R,Wang C,Dai J,Pan W,Xing L,Liu X,Wu J,Liu J,Jia H,Yu B

更新日期：2019-09-27 00:00:00

abstract：:Since diabetes mellitus (DM) is the most common cause of heart failure (HF), it is critically important to clarify whether incretin hormones including glucagon-like peptide-1 (GLP-1), which play an important role in blood glucose control, mediate cardioprotection. There are many lines of basic research evidence indica...

journal_title：International heart journal

authors： Takahashi A,Ihara M,Yamazaki S,Asanuma H,Asakura M,Kitakaze M

更新日期：2015-01-01 00:00:00

abstract：:Heart failure (HF) is a disease with high morbidity and mortality. In patients with HF, decreased cardiac output and blood redistribution results in decreased intestinal perfusion and destruction of intestinal barrier. Microorganisms and endotoxins can migrate into the blood circulation, aggravating systemic inflammat...

journal_title：International heart journal

authors： Jin B,Ji F,Zuo A,Liu H,Qi L,He Y,Wang Q,Zhao P

更新日期：2020-03-28 00:00:00

abstract：:The aim of this study was to investigate whether electrical stimulation of skeletal muscles could represent a rehabilitation alternative for patients with chronic heart failure (CHF). Thirty patients with CHF and NYHA class II-III were randomly assigned to a rehabilitation program using either electrical stimulation o...

journal_title：International heart journal

authors： Dobsák P,Nováková M,Fiser B,Siegelová J,Balcárková P,Spinarová L,Vítovec J,Minami N,Nagasaka M,Kohzuki M,Yambe T,Imachi K,Nitta S,Eicher JC,Wolf JE

更新日期：2006-05-01 00:00:00

abstract：:Prostaglandin F(2alpha) (PGF(2alpha)) stimulates hypertrophic growth of neonatal rat cardiac myocytes, a feature of which includes downregulation of the Ca(2+)-ATPase (SERCA2), a major Ca(2+) transport protein in SR. The molecular mechanisms by which PGF(2alpha) inhibits SERCA2 gene expression remain unknown. We deter...

journal_title：International heart journal

authors： Hara S,Arai M,Tomaru K,Doi H,Koitabashi N,Iso T,Watanabe A,Tanaka T,Maeno T,Suga T,Yokoyama T,Kurabayashi M

更新日期：2008-05-01 00:00:00

abstract：:Acute coronary syndrome (ACS) can develop in patients with mildly to moderately stenotic lesions. However, the angiographic characteristics of lesions in patients who will later develop ACS have not been systematically investigated. For this reason, we examined the earlier angiographic findings of such patients in a r...

journal_title：International heart journal

authors： Yamaya S,Morino Y,Taguchi Y,Ninomiya R,Ishida M,Fusazaki T,Itoh T,Kimura T

更新日期：2020-05-30 00:00:00

abstract：:Left ventricular outflow tract obstruction (LVOTO) is commonly observed in patients with hypertrophic cardiomyopathy (HCM) or left ventricular hypertrophy (LVH). While some patients develop LVOTO at rest, it can also be provoked by physical exertion, and hence termed latent LVOTO (L-LVOTO). Recent reports demonstrated...

journal_title：International heart journal

authors： Semba H,Sawada H,Uejima T,Takeda N,Soma K,Abe H,Yamashita T,Nagai R

更新日期：2012-01-01 00:00:00

abstract：:In this study, we aim to investigate the association of serum uric acid (SUA) with the prevalence of premature ventricular contraction (PVC). The relationship between SUA and the prevalence of PVC in 98,965 subjects (79,034 male subjects, mean age: 51.9 ± 12.6 years old) in the Kailuan cohort study (n = 101,510, age r...

journal_title：International heart journal

authors： Chen Y,Wu S,Li W,Wang B,Lv H,Yang X,Khalid BW,Yin X,Xia Y

更新日期：2018-11-28 00:00:00

abstract：:This study aimed to evaluate the potential associations of intermediate monocytes (CD14(++)CD16(+)) with myocardial remodelling in ST segment elevation myocardial infarction (STEMI) patients with diabetes.A total of 67 STEMI patients with diabetes were enrolled. The control group consisted of 65 STEMI patients without...

journal_title：International heart journal

authors： Lu W,Zhang Z,Fu C,Ma G

更新日期：2015-01-01 00:00:00

abstract：:The 5-hydroxytryptamine2A receptor antagonist sarpogrelate hydrochloride exerts its effect not only by inhibition of platelet aggregation, but also by some pleiotropic effects. We have reported that a low serum lipoprotein lipase (LPL) mass level reflects insulin resistance and may be a risk factor for atherosclerotic...

journal_title：International heart journal

authors： Nagayama D,Ohira M,Saiki A,Shirai K,Tatsuno I

更新日期：2014-01-01 00:00:00

abstract：:Increased QT dispersion (QTd) is a marker of myocardial electrical instability and predicts ventricular arrhythmias and sudden cardiac death. Exercise training (ET) has been shown to reduce both QTd and cardiovascular mortality in various populations. Patients with metabolic syndrome (MS) have been shown to have incre...

journal_title：International heart journal

authors： Guiraud T,Gayda M,Curnier D,Juneau M,Talajic M,Fortier A,Nigam A

更新日期：2010-01-01 00:00:00

abstract：:Worsening of mitral regurgitation (MR) is sometimes observed after closure of an atrial septal defect (ASD). However, since the mechanism of this deterioration remains unclear, the aim of our study was to investigate the effect of left (LV) and right ventricular (RV) geometry on MR after transcatheter closure of ASD.W...

journal_title：International heart journal

authors： Hiraishi M,Tanaka H,Motoji Y,Sawa T,Tsuji T,Miyoshi T,Imanishi J,Kaneko A,Matsumoto K,Shinke T,Hirata K

更新日期：2015-01-01 00:00:00

abstract：:This study tested the therapeutic impact of double-loading dose (i.e., 600 mg) versus standard-loading dose (i.e., 300 mg) of clopidogrel on ST-segment-elevation-myocardial-infarction (STEMI) patients undergoing primary-coronary-intervention (PCI).Between January 2005 and December 2013, a total of 1461 STEMI patients ...

journal_title：International heart journal

authors： Tong MS,Sung PH,Liu CF,Chen KH,Chung SY,Chua S,Chen CJ,Lee WC,Chai HT,Yip HK,Chang HW

更新日期：2017-10-21 00:00:00

abstract：:The aim of this study was to investigate the effects of taurine (Tau) on primary cultured neonatal myocardial cells treated with hydrogen peroxide (H2O2) and the underlying mechanism. Primary cardiac myocytes from neonatal Wistar rats were pre-incubated with Tau, and its effects on cell viability and expression of CaM...

journal_title：International heart journal

authors： Wang J,Qi C,Liu L,Zhao L,Cui W,Tian Y,Liu B,Li J

更新日期：2018-01-27 00:00:00