Abstract：
:Plasma lipoproteins constitute a complex lipid transport system. Very low-density lipoproteins transport triglycerides to peripheral tissues, whereas low-density lipoproteins are the main carriers of cholesterol. Cholesterol transport in low-density lipoprotein enters body cells by way of "low-density lipoprotein receptor pathway" but may also be taken up by macrophages by way of the "scavenger pathway." Excessive influx of cholesterol by way of the "scavenger pathway" may result in deposition of cholesterol in arterial walls and atheroma formation. In a yet incompletely known process of "reverse cholesterol transport," cholesterol is carried away from the tissues to the liver by high-density lipoproteins. The above-mentioned transport processes are regulated by a well-synchronized system that involves several enzymes and lipid transport proteins. Under normal conditions, the lipoprotein system is able to balance the flow of cholesterol and other lipids in both directions between the liver and peripheral tissues. This delicate balance may be disturbed by many factors, including contraceptive steroids. The metabolic steps influenced by administration of contraceptive steroids are summarized.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Tikkanen MJdoi
10.1016/0002-9378(90)90571-nsubject
Has Abstractpub_date
1990-07-01 00:00:00pages
296-304issue
1 Pt 2eissn
0002-9378issn
1097-6868pii
0002-9378(90)90571-Njournal_volume
163pub_type
杂志文章,评审abstract：OBJECTIVE:This study was undertaken to investigate the efficacy of nonoxynol 9 suppositories in the treatment of vaginal trichomoniasis. STUDY DESIGN:In this prospective comparison trial 46 women with documented motile trichomonads found on a wet preparation were randomly assigned to one of two treatment arms: (1) a s...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1067/mob.2000.105388
更新日期：2000-05-01 00:00:00
abstract：:To investigate the effect of medroxyprogesterone acetate therapy upon the immune response and endogenous status of patients with primary or recurrent endometrial adenocarcinoma, 8 patients were treated with progestin therapy as inpatients for 33-80 days. Patients were studied intermittently for up to 72 months. Seru...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(72)90769-7
更新日期：1972-05-15 00:00:00
abstract：OBJECTIVE:This study examined the effects of the chemopreventive agents 4-(N-hydroxyphenyl)retinamide (4-HPR) and alpha-difluoromethylornithine (DFMO) on leiomyoma growth. STUDY DESIGN:Primary cultures of human uterine leiomyomas and matched normal myometrium were established from hysterectomy specimens. After treatme...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2003.09.048
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVE:Our purpose was to test the effects of terbutaline on uterine electric and contractile responses to prostaglandin E2. STUDY DESIGN:In five late-gestation ewes, prostaglandin E2 (22.9 +/- 2.3 micrograms/min for 3 minutes) was given twice at 30-minute intervals during control. Terbutaline sulfate (2 micrograms...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(92)91864-7
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:Examine temporal alterations in vascular angiotensin II receptors (AT(1)R and AT(2)R) and determine vascular response to angiotensin II in growth-restricted offspring. STUDY DESIGN:Offspring of pregnant rats fed low-protein (6%) and control (20%) diet were compared. RESULTS:Prenatal protein restriction repr...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2012.04.010
更新日期：2012-06-01 00:00:00
abstract：:In an attempt to establish the normal ratio of pulmonary artery to aorta diameters at varying gestational ages, the pulmonary artery and aorta diameters of 316 normally grown fetuses between 14 and 39 weeks' gestational age were measured. The ratios for each fetus were derived, and regression analysis was used to eval...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(91)90466-5
更新日期：1991-10-01 00:00:00
abstract：:Although generally safe, combined oral contraceptives (COCs) are associated with risks, including an estimated 2-fold increased relative risk of cardiovascular events. For most women taking COCs for contraception, absolute cardiovascular risks are very low, and the overall risks of COCs are outweighed by the risks of ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2012.01.037
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:Our purpose was to evaluate the role of fetal ultrasonography in prenatal detection of trisomy 21. STUDY DESIGN:A retrospective study was performed on all cases of trisomy 21 diagnosed prenatally or postnatally between January 1990 and December 1993 in the Jerusalem metropolitan area. Our program of prenatal...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(98)70623-4
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:Complex oncologic surgeries, including those for endometrial cancer, increasingly have been concentrated to greater-volume centers, owing to previous research that has demonstrated associations between greater surgical volume and improved outcomes. There is a potential for concentration of care to have unwan...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2019.07.026
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine cardiovascular risk factors in women with a history of hypertensive pregnancy disorders at term (HTP) 2.5 years after pregnancy. STUDY DESIGN:In a multicenter cohort study in The Netherlands from June 2008 through November 2010, cardiovascular risk factors were comp...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ajog.2013.02.016
更新日期：2013-06-01 00:00:00
abstract：:Sixty percent of neonates with Down syndrome have hypoplasia of the middle phalanx of the fifth digit. We demonstrate this finding sonographically between 17 and 20 weeks' gestation in four of five fetuses with Down syndrome. The appearance of this abnormal phalanx as well as the abnormal curvature of the fifth digit ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(88)90517-0
更新日期：1988-07-01 00:00:00
abstract：OBJECTIVES:The purpose of our study was to establish an in vitro tissue culture system to study eicosanoid metabolism in first-trimester trophoblastic tissue. Thromboxane A2, a potent vasoconstrictor, and prostacyclin, a potent vasodilator, were analyzed to evaluate their production in early pregnancy. STUDY DESIGN:Tr...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(12)80036-6
更新日期：1992-10-01 00:00:00
abstract：:In this series of gonadoblastomas it appeared that the germ cells were the motivating force underlying either tumor proliferation or regression. The ultrastructural morphology confirmed the presence of undifferentiated gonadal cells with active steroid synthesis by the interstitial cells. The Call-Exner-like bodies wh...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(76)90359-8
更新日期：1976-06-15 00:00:00
abstract：:In order to properly stage patients with ovarian carcinoma, we are routinely removing and microscopically examining sample aortic lymph nodes in these patients, since aortic lymph node metastases may affect long-term survival. Inasmuch as benign glandular inclusions can be found in pelvic and aortic lymph nodes, we ha...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(80)90450-0
更新日期：1980-03-15 00:00:00
abstract：:Because serum CA-125 concentrations are increased in women with endometriosis, our objective was to determine whether CA-125 levels could be used to differentiate endometriotic from nonendometriotic benign cysts. During a 2-year period, all women who had an endometrioma (n = 33) or a nonendometriotic cyst (n = 27) tha...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(87)80237-5
更新日期：1987-12-01 00:00:00
abstract：:An abnormal result of an umbilical artery Doppler study reflects the presence of placental vascular pathologic mechanisms and identifies pregnancies at increased risk for perinatal mortality. Recent reviews of the clinical utility of umbilical artery Doppler study have concluded that it should not be routinely used as...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/s0002-9378(96)70365-4
更新日期：1996-01-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the risk of cumulative cervical intraepithelial neoplasia (CIN) grade 2 or 3 according to initial colposcopy and directed biopsy results among women with low-grade squamous intraepithelial lesions (LSIL) or human papillomavirus (HPV) DNA positive atypical squamous ce...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2003.461
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:Our purpose was to compare the use of the Iowa Expanded Serum Screening program (maternal serum alpha-fetoprotein, human chorionic gonadotropin, and unconjugated estriol) by obstetricians and family physicians. STUDY DESIGN:A registry was used to identify all obstetricians (160) and family physicians (404) w...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(96)70685-3
更新日期：1996-04-01 00:00:00
abstract：:In 1970 Morgan described an operation designed to meet the problem created by scarring and fibrosis resulting from previous operative procedures to the urethra and bladder neck. In the method, a 2 cm wide polypropylene (Marlex) mesh is placed as a broad hammock to elevate and support the urethrovesical junction with l...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(79)90681-1
更新日期：1979-02-01 00:00:00
abstract：BACKGROUND:Previous studies have shown a decrease in cervical cancer associated with intrauterine device use. It has been hypothesized that intrauterine device use may alter the natural history of human papillomavirus infections, preempting development of precancerous lesions of the cervix and cervical cancer, but the ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2016.11.1053
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:Our purpose was to determine the adequacy of oxygenation, particularly cranial and cardiac oxygenation, in exteriorized fetal lambs on right atrium to artery extracorporeal membrane oxygenation. STUDY DESIGN:Thirteen fetal lambs were placed on right atrium to artery extracorporeal membrane oxygenation betwee...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(96)70423-4
更新日期：1996-02-01 00:00:00
abstract：OBJECTIVE:Before parturition are there useful and valid predictors of successful or unsuccessful vaginal birth after previous cesarean birth that could be used to enhance the obstetric care of a patient and her pregnancy? STUDY DESIGN:The clinical course and outcome of all patients who attempted vaginal birth after ce...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(92)91572-r
更新日期：1992-06-01 00:00:00
abstract：OBJECTIVE:We undertook this study to systematically assess prevailing pain management regimes used at our hospital in women after cesarean delivery. STUDY DESIGN:Between August 1999 and July 2000, all women delivered by cesarean section at Parkland Hospital were assigned to 1 of 4 different pain management strategies:...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2003.10.707
更新日期：2004-05-01 00:00:00
abstract：:We studied the effect of diabetic nephropathy on the course of pregnancy, perinatal outcome, and infant development and determined the influence of pregnancy on maternal hypertension and renal function. Maternal proteinuria usually increased during pregnancy (greater than 3 gm/24 hours in 69%), and hypertension was pr...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(81)90698-0
更新日期：1981-12-01 00:00:00
abstract：:The application of the Home Ovarian Hormone Monitor to the avoidance of pregnancy by periodic abstinence has been explored. No woman had difficulty with the daily urine testing, and their results consistently identified the distinctive hormone pattern of the ovulatory cycle and the day of ovulation and correlated clos...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(11)90568-7
更新日期：1991-12-01 00:00:00
abstract：OBJECTIVE:Our purpose was to determine whether the biguanide oral antihyperglycemic agent metformin increases human placental uptake and transport of glucose to the fetal circulation. STUDY DESIGN:The human single-cotyledon model was used to compare transport of tritiated glucose in the maternal to fetal direction in ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(97)70541-6
更新日期：1997-03-01 00:00:00
abstract：OBJECTIVE:We performed a systematic review to evaluate endovaginal cervical ultrasonography as a predictor of preterm delivery. STUDY DESIGN:Selection criteria were original published English-language reports of prospective studies including women at <37 weeks' gestation with intact amniotic membranes. Parameters and ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/s0002-9378(99)70407-2
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:Carotenoids have antioxidant properties and have been associated with reduced risks of some cancers. We hypothesized that carotenoid intake may reduce the risk of diagnosed uterine leiomyoma (UL). STUDY DESIGN:We evaluated the associations between dietary carotenoids and risk of diagnosed UL in 82,512 premen...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2007.05.033
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:We sought to compare the perinatal outcomes in twin pregnancies with short cervical length (CL) with ultrasound-indicated cerclage (UIC) vs no cerclage (control). STUDY DESIGN:This was a retrospective cohort study of asymptomatic twin pregnancies with transvaginal ultrasound (TVU) CL ≤25 mm at 16-24 weeks fr...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2015.01.031
更新日期：2015-06-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to evaluate the effect of N-acetylcysteine on the activity and secretion of the matrix metalloproteinases in the decidua, amnion, and chorion and the secretion of the tissue inhibitor of matrix metalloproteinase-1. STUDY DESIGN:Samples from eight nonlaboring women were taken at ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(03)00847-0
更新日期：2003-12-01 00:00:00
