Abstract：
OBJECTIVE:This study was undertaken to investigate the efficacy of nonoxynol 9 suppositories in the treatment of vaginal trichomoniasis. STUDY DESIGN:In this prospective comparison trial 46 women with documented motile trichomonads found on a wet preparation were randomly assigned to one of two treatment arms: (1) a single oral dose of 2 g metronidazole and (2) a single 150-mg nonoxynol 9 suppository placed intravaginally for 3 consecutive nights. Cure was determined by a repeated wet preparation examination. After its first year, the study was terminated because of the poor efficacy of the nonoxynol 9 suppositories. RESULTS:Results were available for 33 patients. Three of 17 patients treated with nonoxynol 9 had negative wet preparation results at retest (17.6% cure rate). All 16 patients treated with metronidazole had negative wet preparation results (100% cure rate). All women with nonoxynol 9 failures who were evaluated after treatment with 2 g metronidazole had negative wet preparation results. CONCLUSION:Intravaginal nonoxynol 9 at the tested dose and by the tested method of delivery was not an effective cure for vaginal trichomoniasis.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
Antonelli NM,Diehl SJ,Wright JWdoi
10.1067/mob.2000.105388subject
Has Abstractpub_date
2000-05-01 00:00:00pages
1008-10issue
5eissn
0002-9378issn
1097-6868pii
S0002-9378(00)70138-4journal_volume
182pub_type
临床试验,杂志文章,随机对照试验abstract：BACKGROUND:Interest in medical malpractice and areas of medicolegal vulnerability for practicing obstetricians and gynecologists has grown substantially, and many providers report changing surgical practice out of fear of litigation. Furthermore, education on medical malpractice and risk management is lacking for obste...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2017.05.037
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to describe trends for pelvic floor disorder (PFD)-related ambulatory visits. STUDY DESIGN:Data were derived from the National Ambulatory Medical Care Survey and the National Hospital Ambulatory Care Survey. PFD-related visits were based on ICD-9 codes. We collapsed 12 survey ye...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2009.06.016
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVE:Blastocysts are advanced-stage embryos with high implantation potential; theoretically, limited numbers of blastocysts can be used for embryo transfer to achieve good pregnancy rates with low multiple pregnancy rates. Clinical outcomes of a newly implemented blastocyst transfer program were evaluated. STUDY ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2001.114851
更新日期：2001-06-01 00:00:00
abstract：:With experience, and with the use of a 30-degree forward-oblique viewing telescope, sampling from one of the vessels of the umbilical cord produced at least 0.5 ml of pure fetal blood in 97% of the cases between 14 and 24 weeks' gestation; by aspiration through a short-tipped, 27-gauge, specially constructed needle, a...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(16)32794-6
更新日期：1980-12-15 00:00:00
abstract：OBJECTIVE:Thrombin is a potent uterotonic agent that may play an important role in human parturition. FGL2 is a prothrombinase that cleaves prothrombin to thrombin. The purpose of this study was to determine FGL2 messenger RNA expression in human myometrium and to assess its relationship to the expression of EP3-6 pros...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2003.248
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:We compared metronidazole 0.75% gel (containing 37.5 mg metronidazole per dose) with ovules containing metronidazole 500 mg and nystatin 100,000 U, for intravaginal treatment of bacterial vaginosis (BV). STUDY DESIGN:In a single-blinded trial, symptomatic women with BV by both Amsel and Nugent criteria were ...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ajog.2004.06.089
更新日期：2004-12-01 00:00:00
abstract：:In order to evaluate the ovarian and adrenal contribution to peripheral plasma concentrations of total testosterone (TTe), indixes of the plasma concentrations of free testosterone (FTeI), free 17 beta-hydroxysteroid androgens (FHSI), and testosterone-binding globulin (TeBG) during the menstrual cycle, women were exam...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(76)90688-8
更新日期：1976-12-15 00:00:00
abstract：OBJECTIVE:The purpose of this study was to assess whether endometrial polyps (EMPs) represent cancer precursors. STUDY DESIGN:Age standardized incidence ratios (SIRs) of histologically verified endometrial cancers (EmCas) were estimated in women with EMPs and in women with uterine leiomyomata, which is a condition tha...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2010.03.036
更新日期：2010-09-01 00:00:00
abstract：OBJECTIVE:Our purpose was to determine the frequency and safety of the use of epidural anesthesia and the correlation between bleeding time and maternal-neonatal bleeding complications in a group of pregnant women who participated in a multicenter trial of low-dose aspirin in pregnancy. STUDY DESIGN:Data regarding typ...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/0002-9378(95)90495-6
更新日期：1995-05-01 00:00:00
abstract：:Eighteen women aged 12 to 20 years with congenital cervicovaginal atresia were treated with a new technique of surgical canalization. All are now having regular menses. Two pregnancies have been achieved, with delivery of viable neonates. Surgical correction of this anomaly during adolescence may aid in restoration of...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2000.105740
更新日期：2000-08-01 00:00:00
abstract：:Objections are made to the conclusions of Tolis and Naftolin that bromocriptine should be considered for induction of menstruation in women with normal serum prolactin. Amenorrhea with normal follicle stimulating hormone (FSH) and luteinizing hormone (LH) levels is often resolved spontaneously. Treatment with bromoc...
journal_title：American journal of obstetrics and gynecology
pub_type： 信件
doi：10.1016/0002-9378(78)90452-0
更新日期：1978-01-01 00:00:00
abstract：:This study was undertaken to evaluate the catecholamine response of the fetal rat to insulin-induced hypoglycemia in the mother. Twenty-four Sprague-Dawley rats at day 21 of gestation were used. Hypoglycemia was induced with regular insulin; then at timed intervals, the rats were anesthetized with pentobarbital. When ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(81)90317-3
更新日期：1981-02-15 00:00:00
abstract：:We have investigated the effect of 17beta-estradiol on lung surfactant production in the fetal rabbit. Pregnant rabbits were administered intramuscularly 75microgram of 17beta-estradiol per day at 25 and 26 days' gestation. Control rabbits were similarly injected with the solvent only. At 27 days' gestation the fetuse...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(79)90479-4
更新日期：1979-01-15 00:00:00
abstract：:Evidence suggests an increased risk of ovarian cancer with asbestos exposure. Ovaries and corresponding fallopian tubes were studied by analytic electron microscopy. There was 71.4% agreement between tube and ovary for presence-type of asbestos. The fallopian tube can provide useful information regarding asbestos expo...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(99)70559-4
更新日期：1999-08-01 00:00:00
abstract：OBJECTIVE:Circulating adrenomedullin is increased in pregnancy, and placental and fetal membranes participate significantly in its secretion. Recent studies have suggested a potential role for this peptide in the regulation of fetoplacental circulation and placental hormonal secretion. Because adrenomedullin acts also ...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1067/mob.2001.117189
更新日期：2001-09-01 00:00:00
abstract：BACKGROUND:The established method of screening for preeclampsia is to identify risk factors from maternal demographic characteristics and medical history; in the presence of such factors the patient is classified as high risk and in their absence as low risk. However, the performance of such an approach is poor. We dev...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2018.11.1087
更新日期：2019-02-01 00:00:00
abstract：:We studied differences in the role of genetic factors in prematurity and intrauterine growth retardation with the use of data on 312 Amish singleton live children ascertained from Amish records in Lancaster county, Pennsylvania, between 1969 and 1980. Birth and death certificates were obtained on all children, and inb...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(87)80181-3
更新日期：1987-08-01 00:00:00
abstract：OBJECTIVE:This open-label, two-period, crossover study was conducted to evaluate the effect of a single 150 mg dose of fluconazole on the pharmacokinetics of ethinyl estradiol in healthy female subjects. STUDY DESIGN:Ten subjects regularly taking Ortho-Novum 7/7/7 (Ortho Pharmaceutical, Raritan, N.J.) and 10 subjects ...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9378(98)80016-1
更新日期：1998-02-01 00:00:00
abstract：BACKGROUND:In 2017, the Dutch cervical cancer screening program had replaced the primary cytology-based screening with primary high-risk human papillomavirus-based screening, including the opportunity to participate through self-sampling. Evaluation and balancing benefit (detection of high-grade cervical intraepithelia...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2020.08.026
更新日期：2020-08-13 00:00:00
abstract：BACKGROUND:Preeclampsia (PE) affects 2-3% of all pregnancies and is a major cause of maternal and perinatal morbidity and mortality. The traditional approach to screening for PE is to use a risk-scoring system based on maternal demographic characteristics and medical history (maternal factors), but the performance of s...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2015.11.016
更新日期：2016-05-01 00:00:00
abstract：:Cholecystosonography was performed on 338 obstetric patients, and the gallbladder was successfully visualized in 93% of them. Gallbladder volume increased with duration of pregnancy. Three and one-half percent of the patients had obvious cholelithiasis, and a total of 4.2% had abnormalities. These findings suggest tha...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(82)90434-3
更新日期：1982-11-15 00:00:00
abstract：:The bioavailability of a single dose of intranasal nafarelin was evaluated in 15 healthy female volunteers. Each subject received a 400 micrograms intranasal and a 25 micrograms intravenous dose of nafarelin separated by at least 7 days. Blood samples were obtained frequently after each dose for determination of nafar...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(92)91710-r
更新日期：1992-02-01 00:00:00
abstract：OBJECTIVE:We wanted to test whether the recently described method of using the transferrin receptor system for fluorescence-activated cell-sorter enrichment of nucleated red blood cells can be used for prenatal diagnosis from maternal blood. STUDY DESIGN:Instead of the laborious, expensive fluorescence-activated cell-...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(92)91603-8
更新日期：1992-05-01 00:00:00
abstract：OBJECTIVE:This study was undertaken to study the statistical correlation between lecithin/sphingomylein (L/S) ratio, percent phosphatidylglycerol (%PG), lamellar body count (LBC), and surfactant-to-albumin ratio (TDx-FLM(II)) in amniotic fluid (AF); and derive gestational age-specific (GA) predicted risk of neonatal re...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2005.03.080
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND:Maternal satisfaction with the birth experience is multidimensional and influenced by many factors, including mode of delivery. To date, few studies have investigated maternal satisfaction outside of the immediate postpartum period. OBJECTIVE:This study investigated whether differences in satisfaction based...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.ajog.2017.04.027
更新日期：2017-09-01 00:00:00
abstract：:In a series of 1,000 newborn infants referred to a regional neonatal center, 32 iatrogenically preterm infants were identified. All had been delivered following elective termination of uncomplicated, apparently term pregnancies, without prior documentation of fetal lung maturity or ultrasonic determination of fetal bi...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(78)90717-2
更新日期：1978-12-15 00:00:00
abstract：OBJECTIVE:Our goal was to achieve a good pregnancy rate after in vitro fertilization; more than one embryo, if available, is transferred to the uterine cavity. This is a recognition of the low implantation rates of embryos from in vitro fertilization. A consequence of this can be high-order multiple implantation with o...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0002-9378(97)70197-2
更新日期：1997-08-01 00:00:00
abstract：:Nifedipine, a dihydropyridone calcium entry blocker, has been used with increasing frequency in the treatment of preterm labor. We studied 66 patients in this prospective, randomized trial to evaluate the efficacy and maternal, fetal, and neonatal outcome associated with tocolysis with nifedipine or ritodrine. Deliver...
journal_title：American journal of obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-9378(11)90679-6
更新日期：1990-07-01 00:00:00
abstract：OBJECTIVE:The recommendation to perform a perimortem cesarean delivery within 4 minutes of maternal cardiac arrest was introduced in 1986. This recommendation was based on the assumptions that cardiopulmonary resuscitation is ineffective in the third trimester because of aortocaval compression, and that fetal and perha...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.ajog.2005.02.038
更新日期：2005-06-01 00:00:00
abstract：:Previous investigations have shown that the human placenta is a complex organ with different zones, each with a unique morphology. These zonal morphologic difference have been related to a probable blood PO2 gradient operating in the intervillous space. This study describes zonal variations in the vertical plane of th...
journal_title：American journal of obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0002-9378(78)90007-8
更新日期：1978-04-01 00:00:00
