Iatrogenic prematurity due to elective termination of the uncomplicated pregnancy: a major perinatal health care problem.

Abstract:

:In a series of 1,000 newborn infants referred to a regional neonatal center, 32 iatrogenically preterm infants were identified. All had been delivered following elective termination of uncomplicated, apparently term pregnancies, without prior documentation of fetal lung maturity or ultrasonic determination of fetal biparietal diameter. Associated acute morbidity included asphyxia neonatorum in 10, respiratory distress syndrome in 24, and pneumothorax or pneumomediastinum in nine patients. One infant died. Hospital costs totaled $150,643, for a mean of $4,701 per patient. The unexpected premature births were associated with major parental grief reactions and alterations in their daily activities, Iatrogenic prematurity is a major regional health care problem which, when viewed on a national basis, may affect thousands of newborn infants and their families annually. Our data suggest the need for more accurate assessment of fetal maturity, before elective termination of pregnancy, by well-established techniques.

journal_name

Am J Obstet Gynecol

authors

Flaksman RJ,Vollman JH,Benfield DG

doi

10.1016/0002-9378(78)90717-2

subject

Has Abstract

pub_date

1978-12-15 00:00:00

pages

885-8

issue

8

eissn

0002-9378

issn

1097-6868

pii

0002-9378(78)90717-2

journal_volume

132

pub_type

杂志文章
  • Transient blood oxygen desaturation, hypercapnia, and coagulopathy after operative hysteroscopy with glycine used as the distending medium.

    abstract:OBJECTIVE:Our purpose was to report transient complications associated with operative hysteroscopy with glycine used as the distending medium. STUDY DESIGN:All the operative hysteroscopies performed over a 6-month period by a single operator were examined. The blood oxygenation and end-tidal carbon dioxide concentrati...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(94)70377-9

    authors: Goldenberg M,Zolti M,Seidman DS,Bider D,Mashiach S,Etchin A

    更新日期:1994-01-01 00:00:00

  • Cervical priming prior to dilatation and evacuation: a comparison of methods.

    abstract::Vaginal administration of prostaglandin analogues resulted in cervical changes that facilitated dilatation and evacuation in 80 patients in the late first trimester and the second trimester of pregnancy. When 0.5 mg and 1.0 mg of 15(S)-15-methyl-prostaglandin F2 alpha (15-ME-PGF2 alpha) was compared to 30 and 60 mg of...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90179-x

    authors: Lauersen NH,Den T,Iliescu C,Wilson KH,Graves ZR

    更新日期:1982-12-15 00:00:00

  • Sex differences in lung and adrenal neurosympathetic development in rabbits.

    abstract::To assess the possible mechanism for the increased incidence and severity of the respiratory distress syndrome (RDS) in male versus female infants, we studied neurosympathetic development in the lung and adrenal glands in male and female fetal and newborn rabbits. Tissue levels of catecholamines, norepinephrine (NE), ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(16)32593-5

    authors: Padbury JF,Hobel CJ,Lam RW,Fisher DA

    更新日期:1981-09-15 00:00:00

  • Danazol: endocrine pharmacology and therapeutic applications.

    abstract::The options for the medical management of endometriosis have been expanded by the introduction of the synthetic steroid, danazol. The results of large clinical studies suggest that danazol treatment produces significant improvement in the symptoms, signs, and laparoscopic findings of endometriosis. The original studie...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/0002-9378(81)90611-6

    authors: Barbieri RL,Ryan KJ

    更新日期:1981-10-15 00:00:00

  • The effect of sex steroids on the skeleton in premenopausal women.

    abstract::Whereas peak bone mass is genetically determined, the skeletal growth, maturation, and maintenance required to reach this peak may be influenced by physical activity, ovarian function, and nutrition. Estrogen deficiency at menopause leads to increased skeletal remodeling and loss of bone mass, which can result in oste...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/0002-9378(92)91400-5

    authors: Lindsay R

    更新日期:1992-06-01 00:00:00

  • Obesity levels in a national cohort of women 9 months after delivery.

    abstract:OBJECTIVE:The purpose of this study was to examine the relationship between maternal obesity that is calculated 9 months after delivery and sociodemographic variables. STUDY DESIGN:A national cohort of mothers was sampled 9 months after delivery as part of the Growing Up in Ireland Study Infant Cohort. Sociodemographi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2013.04.020

    authors: Turner MJ,Layte R

    更新日期:2013-08-01 00:00:00

  • Neuromodulatory regulation of gonadotropin-releasing hormone pulsatile discharge in women.

    abstract::The pulsatile release of gonadotropin-releasing hormone and the consequent secretion of gonadotropins are regulated by a complex interplay of steroids, neuropeptides, catecholamines, and environmental factors. Estrogen and progesterone influence the amplitude and frequency of luteinizing hormone pulsatile secretion. T...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/0002-9378(90)91436-g

    authors: Jaffe RB,Plosker S,Marshall L,Martin MC

    更新日期:1990-11-01 00:00:00

  • Diurnal glycemic profile in obese and normal weight nondiabetic pregnant women.

    abstract:OBJECTIVE:A paucity of data exists concerning the normal glycemic profile in nondiabetic pregnancies. Using a novel approach that provides continuous measurement of blood glucose, we sought to evaluate the ambulatory daily glycemic profile in the second half of pregnancy in nondiabetic women. STUDY DESIGN:Fifty-seven ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2004.06.059

    authors: Yogev Y,Ben-Haroush A,Chen R,Rosenn B,Hod M,Langer O

    更新日期:2004-09-01 00:00:00

  • Knot integrity with nonidentical and parallel sliding knots.

    abstract:OBJECTIVE:The study was performed to test the knot integrity of parallel and nonidentical sliding knots with the use of monofilament suture. STUDY DESIGN:We investigated the proportion of parallel sliding knots that become untied compared with nonidentical sliding knots in four different monofilament suture configurat...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(03)00947-5

    authors: Ivy JJ,Unger JB,Mukherjee D

    更新日期:2004-01-01 00:00:00

  • Risk factors for bacterial vaginosis during pregnancy among African American women.

    abstract:OBJECTIVE:The objective of the study was to examine risk factors for bacterial vaginosis (BV) during pregnancy among African American women. STUDY DESIGN:As part of a study of preterm birth, African American women residing in Baltimore, MD, were recruited from prenatal care sites. Women enrolled prenatally (between 22...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ajog.2007.03.085

    authors: Trabert B,Misra DP

    更新日期:2007-11-01 00:00:00

  • Blunt vs. sharp uterine expansion at lower segment cesarean section delivery: a systematic review with metaanalysis.

    abstract:OBJECTIVE:Blunt vs sharp expansion of the uterine incision at cesarean delivery has been investigated as a technique primarily to reduce intraoperative blood loss. The objective of this systematic review was to compare the effects of either intervention on maternal outcomes. STUDY DESIGN:A systematic review with metaa...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ajog.2012.10.886

    authors: Xu LL,Chau AM,Zuschmann A

    更新日期:2013-01-01 00:00:00

  • The epidemiology of threatened preterm labor: a prospective cohort study.

    abstract:OBJECTIVE:The purpose of this study was to describe the occurrence, timing, and outcomes of hospital-based diagnoses of preterm labor. STUDY DESIGN:Administrative records identified hospital admissions for preterm labor among 2534 women in an ongoing cohort study. Factors that were considered risks for prematurity wer...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2004.12.055

    authors: McPheeters ML,Miller WC,Hartmann KE,Savitz DA,Kaufman JS,Garrett JM,Thorp JM

    更新日期:2005-04-01 00:00:00

  • Outcomes of transvaginal uterosacral ligament suspension: systematic review and metaanalysis.

    abstract::This systematic review of uterosacral ligament suspension provides a metaanalysis of anatomic outcomes and a summary of subjective outcomes. A successful anatomic outcome was considered present when women had "optimal" or "satisfactory" (pelvic organ prolapse quantification system stage 0 or 1) outcomes. In the anteri...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.ajog.2009.07.052

    authors: Margulies RU,Rogers MA,Morgan DM

    更新日期:2010-02-01 00:00:00

  • Multiplexed analysis of circulating cell-free fetal nucleic acids for noninvasive prenatal diagnostic RHD testing.

    abstract:OBJECTIVE:The objective of the study was the evaluation of a novel multiplex assay to detect fetal Rh blood group D-antigen gene (RHD) loci in maternal plasma from RhD-negative, pregnant women. STUDY DESIGN:An RHD genotyping assay was designed to detect exons 4, 5, 7, and 10 and RHDΨ (pseudogene) of the RHD gene along...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2010.09.028

    authors: Tynan JA,Angkachatchai V,Ehrich M,Paladino T,van den Boom D,Oeth P

    更新日期:2011-03-01 00:00:00

  • Hexamethylmelamine chemotherapy for persistent or recurrent epithelial ovarian cancer.

    abstract::The purpose of this study was to determine the activity and toxicity of hexamethylmelamine chemotherapy in patients with persistent or recurrent epithelial ovarian cancer. Forty-nine women received hexamethylmelamine 100 to 150 mg/day for 14 days, repeated at 4-week intervals. All patients had previously received at l...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-9378(91)90287-2

    authors: Moore DH,Fowler WC Jr,Jones CP,Crumpler LS

    更新日期:1991-09-01 00:00:00

  • Antepartum chronic fetal vesicoamniotic shunts for obstructive uropathy: A report of two cases.

    abstract::Two fetuses with obstructive uropathy characterized by striking oligohydramnios and dilatation of the urinary collecting system were identified by ultrasound and treated by percutaneous insertion of a long-term vesicoamniotic silicone rubber shunt. Both fetuses were less than 16 weeks' gestation at diagnosis and less ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(83)90685-3

    authors: Manning FA,Harman CR,Lange IR,Brown R,Decter A,MacDonald N

    更新日期:1983-04-01 00:00:00

  • Cadmium levels in maternal blood, fetal cord blood, and placental tissues of pregnant women who smoke.

    abstract::Previous studies have reported that cigarette smoking is a major source of exposure to cadmium (Cd). This study was carried out to determine the degree of exposure to Cd of pregnant women who smoke and to determine the degree of exposure to Cd of pregnant women who smoke and to determine the disposition of the Cd in t...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90786-4

    authors: Kuhnert PM,Kuhnert BR,Bottoms SF,Erhard P

    更新日期:1982-04-15 00:00:00

  • Bioavailability of nafarelin in healthy volunteers.

    abstract::The bioavailability of a single dose of intranasal nafarelin was evaluated in 15 healthy female volunteers. Each subject received a 400 micrograms intranasal and a 25 micrograms intravenous dose of nafarelin separated by at least 7 days. Blood samples were obtained frequently after each dose for determination of nafar...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(92)91710-r

    authors: Chaplin MD

    更新日期:1992-02-01 00:00:00

  • Quantitative analysis of fetal pulmonary vasculature by 3-dimensional power Doppler ultrasonography in isolated congenital diaphragmatic hernia.

    abstract:OBJECTIVE:The purpose of this study was to evaluate the potential of 3-dimensional (3D) power Doppler imaging to predict neonatal outcome and pulmonary arterial hypertension (PAH) in congenital diaphragmatic hernia (CDH). STUDY DESIGN:In this prospective observational study, 3D-power Doppler ultrasonography was perfor...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2006.05.010

    authors: Ruano R,Aubry MC,Barthe B,Mitanchez D,Dumez Y,Benachi A

    更新日期:2006-12-01 00:00:00

  • Human chorionic gonadotropin, prolactin, estriol, and dehydroepiandrosterone sulfate concentrations in cord blood of premature and term newborn infants: relationship to the sex of the neonate.

    abstract::Although the composition of human chorionic gonadotropin, prolactin, estriol, and dehydroepiandrosterone sulfate in the umbilical cord blood has been studied, less information is available on the effect of fetal sex on the cord blood concentrations. We assayed these hormones in cord blood from 405 newborn infants deli...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(87)90291-2

    authors: Yuen BH,Mincey EK

    更新日期:1987-02-01 00:00:00

  • Effects of nomegestrol acetate on spontaneous and sulprostone-induced uterine contractions in pregnant cynomolgus monkeys monitored by telemetry.

    abstract:OBJECTIVE:Our purpose was to study the effects of the progestomimetic compound nomegestrol acetate on spontaneous and sulprostone-induced uterine contractility in pregnant cynomolgus monkeys. STUDY DESIGN:Intrauterine pressure was continuously monitored with use of an implanted intraamniotic catheter and a telemetric ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(98)70643-x

    authors: Carbonne B,Cabrol D,Clerget MS,Germain G

    更新日期:1998-01-01 00:00:00

  • Interferon-gamma expression is an independent prognostic factor in ovarian cancer.

    abstract:BACKGROUND:Epithelial ovarian cancer prognosis is improved by the presence of intratumoral CD3 + T cells, which are known to produce interferon-gamma. We therefore speculated that interferon-gamma expression in ovarian cancer-infiltrating T-lymphocytes might cause better prognosis. PATIENTS AND METHODS:Reverse transcr...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2004.05.007

    authors: Marth C,Fiegl H,Zeimet AG,Müller-Holzner E,Deibl M,Doppler W,Daxenbichler G

    更新日期:2004-11-01 00:00:00

  • Restructuring residency training in obstetrics and gynecology.

    abstract::This essay presents a brief review of the history advocating a restructuring of residency training to increase the flexibility of the experience. The advantages for both the general obstetrician-gynecologist and the subspecialist are reviewed. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-9378(99)70246-2

    authors: Bissonnette JM,Gabbe SG,Hammond CB,MacDonald PC,Polan ML,Roberts JM

    更新日期:1999-03-01 00:00:00

  • Diurnal and other cyclic variations in human fetal heart rate near term.

    abstract::In 10 healthy women near term, fetal heart rate, as monitored from an abdominal electrocardiogram, and its variation were analyzed over 24 hours. During the daytime, this was combined with real-time scanning for fetal breathing and movements. There was an episodic change in high and low pulse (R-R) interval variation ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90757-8

    authors: Visser GH,Goodman JD,Levine DH,Dawes GS

    更新日期:1982-03-01 00:00:00

  • Objective structured assessment of technical skills for repair of fourth-degree perineal lacerations.

    abstract:OBJECTIVE:The objective of this study was to assess the reliability and validity of an objective structured assessment of technical skills (OSATS) for repair of fourth-degree obstetric lacerations on a surgical model. STUDY DESIGN:Three blinded judges reviewed recordings of 20 junior and 20 senior obstetrics-gynecolog...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2008.07.054

    authors: Siddiqui NY,Stepp KJ,Lasch SJ,Mangel JM,Wu JM

    更新日期:2008-12-01 00:00:00

  • Embryocidal action of a bis(dichloroacetyl)-diamine: an oral abortifacient for rats.

    abstract::It is demonstrated that for rats N,N'-bis(dischloroacetyl)-1,8-octamethylenediamine (Win 18,446) is a highly efficient embryocidal N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine It was previously used to supress spermatogenesis in man and other mammals. In the initial rat studies, a fixed dosage of Win 18,446 was...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(74)90117-3

    authors: Oster G,Salgo MP,Taleporos P

    更新日期:1974-07-01 00:00:00

  • Patient-recorded domiciliary fetal monitoring.

    abstract::Domiciliary fetal monitoring via a telephone link has been in clinical use at the Royal Free Hospital for 2 years, during which time 858 traces of 134 patients who were moderately at risk have been transmitted to the hospital. All recognized abnormal heart rate patterns were detected during the study period. In seven ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)90411-y

    authors: Lindsay PC,Beveridge R,Tayob Y,Irvine LM,Vellacott ID,Giles JA,Hussain SY,O'Brien PM

    更新日期:1990-02-01 00:00:00

  • Ovine placental perfusion balance: effect of marijuana smoke.

    abstract::This study was designed to test the hypothesis that maternal marijuana smoking impairs placental oxygen transfer in late ovine pregnancy by disrupting perfusion balance between the maternal and fetal placental circulations. Placental hemodynamics were assessed in nine chronically prepared ewes 1 hour after exposure to...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(88)90569-8

    authors: Clapp JF 3rd,Keve TM,Vial C,McLaughlin MK

    更新日期:1988-12-01 00:00:00

  • Maternal and cord blood background mercury levels: a longitudinal surveillance.

    abstract::Fifty-seven prenatal patients with no known exposure to the element mercury, or any of its compounds, were observed for change in whole blood total mercury concentration from the initial prenatal clinic examination through delivery and postpartum hospitalization. On hospital admission for labor and delivery, whole blo...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90087-4

    authors: Kuntz WD,Pitkin RM,Bostrom AW,Hughes MS

    更新日期:1982-06-15 00:00:00

  • Pharmacokinetics of cefuroxime in pregnancy.

    abstract::Most pharmacokinetic studies of antibodies in pregnancy have been carried out at the time of abortion or delivery. Whether such data represent pregnancy as such is not known. The present study compares the pharmacokinetic properties of cefuroxime in seven women during pregnancy, at delivery, and after delivery. After ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(16)32526-1

    authors: Philipson A,Stiernstedt G

    更新日期:1982-04-01 00:00:00