Serum CA-125 in the evaluation of benign adnexal cysts.

Abstract:

:Because serum CA-125 concentrations are increased in women with endometriosis, our objective was to determine whether CA-125 levels could be used to differentiate endometriotic from nonendometriotic benign cysts. During a 2-year period, all women who had an endometrioma (n = 33) or a nonendometriotic cyst (n = 27) that was greater than or equal to 4 cm were included. Serum CA-125 levels were measured by an immunoradiometric assay, and the mean concentrations in women with an endometriotic cyst increased as the diameter of the cyst increased. The mean CA-125 concentrations in women with cysts greater than or equal to 4 cm were 53 +/- 2 U/ml in 19 women with an endometriotic cyst, 11 +/- 1 U/ml in 20 women with a nonendometriotic cyst, and 15 +/- 1 U/ml in 7 women with a nonendometriotic cyst and endometriosis. In the fluid of 10 endometriomas, the mean CA-125 concentration was 290 +/- 94 X 10(3) U/ml (range 10 to 900 X 10(3) U/ml). With cysts diameters greater than or equal to 4 cm, 19 of 19 women with endometriotic cysts, zero of seven women with nonendometriotic cysts and endometriosis, and zero of 20 women with nonendometriotic cysts had CA-125 concentrations greater than or equal to 20 U/ml (99% upper normal limit). We conclude that serum CA-125 determinations offer an excellent method to differentiate endometriotic from nonendometriotic benign cysts.

journal_name

Am J Obstet Gynecol

authors

Pittaway DE,Fayez JA,Douglas JW

doi

10.1016/s0002-9378(87)80237-5

subject

Has Abstract

pub_date

1987-12-01 00:00:00

pages

1426-8

issue

6

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(87)80237-5

journal_volume

157

pub_type

杂志文章
  • Plasma estrogens in euthyroid and thyrotoxic women.

    abstract::Plasma levels of estrogen were measured daily by radioimmunoassay for 28 consecutive days in 12 healthy euthyroid women and 15 thyrotoxic women (10 with hypomenorrhea and 5 with amenorrhea) before commencement of therapy (except in one case) in an effort to increase understanding of the relationship between the thyroi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(75)90732-2

    authors: Akande EO

    更新日期:1975-08-01 00:00:00

  • Ultrasonic ratio of fetal thoracic to abdominal circumference: an association with fetal pulmonary hypoplasia.

    abstract::Real time ultrasound was used in pregnant women who were considered to be at risk for development of pulmonary hypoplasia (n = 26). The population consisted of women who had either premature rupture of membranes (n = 16) or oligohydramnios (n = 10). The ratio calculated by comparing the fetal thoracic circumference to...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(87)80046-7

    authors: Johnson A,Callan NA,Bhutani VK,Colmorgen GH,Weiner S,Bolognese RJ

    更新日期:1987-09-01 00:00:00

  • Fetal growth retardation as a complication of pregnancy in patients with neurofibromatosis.

    abstract::Neurofibromatosis adversely affects reproductive performance. Fetal growth retardation as a complication of pregnancy in patients with neurofibromatosis had not been widely documented. The present cases suggest that pregnant patients with neurofibromatosis may have an increased risk for growth-retarded babies. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(87)80167-9

    authors: Blickstein I,Lancet M

    更新日期:1987-08-01 00:00:00

  • Prenatal sex determination by fluorescent staining of the cervical smear for the presence of a Y chromosome: an evaluation.

    abstract::If the parents do not want to take the 50% chance that a male fetus will be involved with an x-linked disease, it is desirable to predict fetal sex early enough to safely terminate pregnancy. Slides obtained from midcervical smears of 20 consecutive patients at different stages of gestation were stained with .5% aque...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(73)90541-3

    authors: Goldstein AI,Lukesh RC,Ketchum M

    更新日期:1973-03-15 00:00:00

  • Gap junction currents in cultured muscle cells from human myometrium.

    abstract:OBJECTIVE:The electrophysiologic properties of gap junctions between human myometrial smooth muscle cells were studied. STUDY DESIGN:Double whole-cell patch clamp recordings were made on pairs of cells from primary cultures of myometrial cells from women undergoing cesarean section. Macroscopic gap junction currents w...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(98)70443-0

    authors: Miyoshi H,Boyle MB,MacKay LB,Garfield RE

    更新日期:1998-03-01 00:00:00

  • A model for the antiphospholipid antibody syndrome: monoclonal antiphosphatidylserine antibody induces intrauterine growth restriction in mice.

    abstract:OBJECTIVE:Antiphospholipid antibodies are associated with clinical intrauterine growth restriction. In this study we investigated whether immunoglobulin M monoclonal antibodies against phosphatidylserine or cardiolipin or cross-reactive with both phospholipids would induce intrauterine growth restriction in an experime...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(96)70453-2

    authors: Vogt E,Ng AK,Rote NS

    更新日期:1996-02-01 00:00:00

  • Medication effects on midtrimester maternal serum screening.

    abstract:OBJECTIVE:To determine whether medication classes are associated with alterations in concentrations of Quad screen analytes or the screen-positive rate. STUDY DESIGN:We conducted a retrospective cohort study of women with singleton gestations who received prenatal care and had a Quad screen performed in the University...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2009.07.013

    authors: Pekarek DM,Chapman VR,Neely CL,Ramsey PS,Biggio JR

    更新日期:2009-12-01 00:00:00

  • Prognostic factors and complication rates for cervical cerclage: a review of 482 cases.

    abstract::Charts from 482 singleton pregnancies undergoing cerclage placement in patients over a 6-year period were reviewed. Cervical dilatation at time of surgery, number of previous spontaneous losses, and gestational age at placement were key determinants of outcome. The most frequent complication, premature rupture of the ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(91)90283-w

    authors: Treadwell MC,Bronsteen RA,Bottoms SF

    更新日期:1991-09-01 00:00:00

  • Maternal oxygen transport variables during the third trimester of normal pregnancy.

    abstract:OBJECTIVE:The aim of this study was to measure and calculate oxygen transport variables in uncomplicated term pregnancies. STUDY DESIGN:Ten normotensive primiparous women between 36 and 38 weeks' gestation underwent pulmonary and radial arterial catheterization as part of a larger study. Seven women had studies repeat...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(99)70223-1

    authors: Hankins GD,Clark SL,Uckan E,Van Hook JW

    更新日期:1999-02-01 00:00:00

  • Cesarean scar pregnancy: noninvasive and effective treatment with high-intensity focused ultrasound.

    abstract:OBJECTIVE:The aim of this preliminary study was to investigate whether ultrasound-guided high-intensity focused ultrasound (HIFU) can play a role in treating cesarean scar pregnancy (CSP). STUDY DESIGN:Between November 2011 and December 2012, 16 patients with CSP were treated with ultrasound-guided HIFU ablation. Succ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.ajog.2014.04.024

    authors: Xiao J,Zhang S,Wang F,Wang Y,Shi Z,Zhou X,Zhou J,Huang J

    更新日期:2014-10-01 00:00:00

  • Clinical experience reported by candidates for the American Board of Obstetrics and Gynecology 1995 and 1997 oral examinations.

    abstract:OBJECTIVE:The purpose of this study was to report the clinical experience collated from the 1995 and 1997 case list summary sheets of United States and Canadian active candidates who were completing the American Board of Obstetrics and Gynecology oral examination for the first time. STUDY DESIGN:Data from the case lis...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2001.119181

    authors: Chez RA,Droegemueller W,Gant NF Jr,O'sullivan MJ

    更新日期:2001-12-01 00:00:00

  • Synergistic effect of relaxin and progesterone on cyclic adenosine 3',5'-monophosphate levels in the rat uterus.

    abstract::Cyclic adenosine 3',5'-monophosphate is known to modulate smooth muscle contractility. Because both relaxin and progesterone have been demonstrated to affect myometrial cyclic adenosine monophosphate activity, we questioned whether the previously observed synergism of these two hormones in inhibiting uterine contracti...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(88)90564-9

    authors: Grazi RV,Goldsmith LT,Schmidt CL,Von Hagen S,Weiss G

    更新日期:1988-12-01 00:00:00

  • Low-dose aspirin in the prevention of preeclampsia and fetal growth retardation: rationale, mechanisms, and clinical trials.

    abstract::Preeclampsia is characterized by a functional imbalance between vascular prostacyclin and thromboxane A2 production. On the basis of the hypothesis that preeclampsia is at least partially caused by an increase in thromboxane A2, some studies attempted to correct this pathologic condition by pharmacologic manipulation ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-9378(12)90917-5

    authors: Dekker GA,Sibai BM

    更新日期:1993-01-01 00:00:00

  • Effects of recombinant human relaxin on pregnant rat uterine artery and myometrium in vitro.

    abstract:OBJECTIVE:The purpose of this study was to evaluate the effects of recombinant human relaxin on the uterine artery and myometrial contractility in pregnant rats. STUDY DESIGN:Uterine artery and myometrial rings from mid and term pregnant rats were used. Relaxin effect was studied on phenylephrine-induced contraction i...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2003.454

    authors: Longo M,Jain V,Vedernikov YP,Garfield RE,Saade GR

    更新日期:2003-06-01 00:00:00

  • The neuropeptide histidyl proline diketopiperazine throughout human pregnancy: an inverse correlation with amniotic fluid prolactin.

    abstract::Histidyl proline diketopiperazine values have been established in human amniotic fluid (n = 81) and maternal serum (n = 36) throughout gestation (10 to 42 weeks). Newborn cord serum (n = 10) and first-voided fetal urine (n = 10) levels were also documented. These measurements reveal increasing amniotic fluid levels wi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)90998-m

    authors: Wolf GC,Hilton CW,Prasad C,Miller JM Jr,Thorneycroft IH

    更新日期:1990-03-01 00:00:00

  • Type and screen: a safe and effective preoperative blood ordering policy with emphasis on its use in obstetrics and gynecology.

    abstract::In September, 1979, the Transfusion Committee at the University of Texas Medical Branch in Galveston implemented a preoperative blood ordering policy of type and screen (TS) for selected surgical procedures. During the first year in which this policy was in force, 2,301 TS requests were received, most of them for pati...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90762-1

    authors: Patten E,Alperin JB

    更新日期:1982-03-01 00:00:00

  • Cervicoisthmic cerclage: transabdominal vs transvaginal approach.

    abstract:OBJECTIVE:We sought to compare the outcomes of cervicoisthmic (CI) cerclage using traditional transabdominal (TA) approach vs the lesser used transvaginal (TV) approach. STUDY DESIGN:We conducted a retrospective cohort study of women who underwent placement of a CI cerclage. RESULTS:Before CI placement, the abdominal...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2009.03.020

    authors: Witt MU,Joy SD,Clark J,Herring A,Bowes WA,Thorp JM

    更新日期:2009-07-01 00:00:00

  • A vasodepressor substance of the human placenta.

    abstract::The authors of this article have been able to isolate from the human placenta large amounts of a vasodepressor substance able to cause relaxation of the duodenum, and decrease blood pressure in rats. The vasoactive substance was obtained only by extraction with dichloroacetic acid, hydrochloric acid, and with methyle...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(69)90290-7

    authors: Ryan WL,Coronel DM,Johnson RJ

    更新日期:1969-12-15 00:00:00

  • Transdermal estrogen reduces vascular resistance and serum cholesterol in postmenopausal women.

    abstract:OBJECTIVE:Our aim was to compare the effects of transdermal versus oral estrogens on vascular resistance index, mean arterial pressure, serum lipid concentrations, norepinephrine, and left ventricular structure. STUDY DESIGN:Ten postmenopausal women received transdermal estradiol (0.05 mg/d) plus cyclic oral progester...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2001.112104

    authors: West SG,Hinderliter AL,Wells EC,Girdler SS,Light KC

    更新日期:2001-04-01 00:00:00

  • The maternal health clinic: an initiative for cardiovascular risk identification in women with pregnancy-related complications.

    abstract:OBJECTIVE:Women who develop certain common pregnancy complications have a greater chance of developing cardiovascular disease (CVD) later in life. However, most health care providers do not provide postpartum cardiovascular risk counselling or follow-up. The Maternal Health Clinic was established to address this gap in...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2013.12.001

    authors: Cusimano MC,Pudwell J,Roddy M,Cho CK,Smith GN

    更新日期:2014-05-01 00:00:00

  • Long-term outcome of MR-guided focused ultrasound treatment and laparoscopic myomectomy for symptomatic uterine fibroid tumors.

    abstract:BACKGROUND:Fibroid tumors are the most common benign tumors in women of reproductive age. Treatment is usually indicated for those who are symptomatic, with different techniques being used. OBJECTIVE:The purpose of this study was to compare the long-term outcome of laparoscopic myomectomy with magnetic resonance-guide...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2018.09.002

    authors: Mohr-Sasson A,Machtinger R,Mashiach R,Nir O,Inbar Y,Maliyanker N,Goldenberg M,Rabinovici J

    更新日期:2018-10-01 00:00:00

  • Placental histology in fetuses between 18 and 23 weeks' gestation with abnormal karyotype.

    abstract::Placentas from karyotypically abnormal fetuses (18 to 23 weeks' gestation) were analyzed prospectively at the light microscopic level. Group I consisted of 14 control placentas. Group II consisted of 14 placentas from fetuses with an abnormal karyotype. Secondary and tertiary stem villi counts, small muscular artery c...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)90704-b

    authors: Kuhlmann RS,Werner AL,Abramowicz J,Warsof SL,Arrington J,Levy DL

    更新日期:1990-10-01 00:00:00

  • Pregnancy hemoperitoneum and placenta percreta in a patient with previous pelvic irradiation and ovarian failure.

    abstract::Placenta percreta in a patient with previous pelvic irradiation has never been described. Reported is a case of placenta percreta with hemoperitoneum associated with a second-trimester incomplete abortion in a patient with previous pelvic irradiation and ovarian failure. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)90018-3

    authors: Pridjian G,Rich NE,Montag AG

    更新日期:1990-05-01 00:00:00

  • Circulatory effects of magnesium sulfate in normotensive and renal hypertensive pregnant sheep.

    abstract::We have studied the effects of magnesium sulfate (MgSO4) administration in chronically instrumented normotensive and hypertensive pregnant sheep. Animals of 90 to 144 days' gestation were divided in two groups; those with normotensive arterial pressure and those in which renovascular hypertension had been produced. Ou...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(77)90255-1

    authors: Dandavino A,Woods JR Jr,Murayama K,Brinkman CR 3rd,Assali NS

    更新日期:1977-04-01 00:00:00

  • Evidence-based surgery for cesarean delivery.

    abstract:OBJECTIVE:The purpose of this study was to provide evidenced-based guidance for surgical decisions during cesarean delivery. STUDY DESIGN:We performed MEDLINE, PubMed, EMBASE, and COCHRANE searches with the terms cesarean section, cesarean delivery, cesarean, pregnancy, randomized trials, and each technical aspect of ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ajog.2005.03.063

    authors: Berghella V,Baxter JK,Chauhan SP

    更新日期:2005-11-01 00:00:00

  • Transabdominal amnioinfusion in oligohydramnios at term before induction of labor with intact membranes: a randomized clinical trial.

    abstract:OBJECTIVE:Our purpose was to determine the effectiveness of transabdominal amnioinfusion before induction of labor in reducing the incidence of fetal distress in pregnancies with oligohydramnios at term. STUDY DESIGN:Between June 1991 and September 1994 primiparous women with ultrasonographic evidence of oligohydramni...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-9378(96)70163-1

    authors: Vergani P,Ceruti P,Strobelt N,Locatelli A,D'Oria P,Mariani S

    更新日期:1996-08-01 00:00:00

  • Estrogen increases inducible nitric oxide synthase gene expression.

    abstract:OBJECTIVE:The goal of this study was to determine whether estrogen increases the expression of the inducible nitric oxide synthase gene. STUDY DESIGN:An inducible nitric oxide synthase fusion gene was created with its promoter and the reporter gene, luciferase. COS cells were transfected transiently with the fusion ge...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2003.350

    authors: Walsh LS,Ollendorff A,Mershon JL

    更新日期:2003-05-01 00:00:00

  • Nitrous oxide amniodistention compared with fluid amniodistention reduces operation time while inducing no changes in fetal acid-base status in a sheep model for endoscopic fetal surgery.

    abstract:OBJECTIVE:Our purpose was to evaluate in a sheep model for endoscopic fetal surgery the impact of nitrous oxide-gas amniodistention compared with fluid amniodistention on duration of surgery, hemorrhagic events, and fetomaternal acid-base status. STUDY DESIGN:Pregnant ewes (n = 16) at 92 to 104 days of gestation (term...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2002.120482

    authors: Gratacós E,Wu J,Devlieger R,Bonati F,Lerut T,Vanamo K,Deprest JA

    更新日期:2002-03-01 00:00:00

  • Exercise in pregnancy. II. Fetal responses.

    abstract::Healthy pregnant women underwent a mild exercise study to evaluate the effects of this amount of work on their fetuses. The results indicated that there were no direct correlations between exercise and fetal body or breathing movements at this particular work intensity (2.33 m). We found a relationship between the mat...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(83)90003-0

    authors: Platt LD,Artal R,Semel J,Sipos L,Kammula RK

    更新日期:1983-11-01 00:00:00

  • The California octuplets and the duties of reproductive endocrinologists.

    abstract::The recent birth of octuplets unleashed a firestorm of publicity, casting a harsh light on the mother and her presumed inadequacies as a parent. It also raised questions about the role of reproductive endocrinologists. Herein we consider 3 aspects of this question: should reproductive endocrinologists consider the eco...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2009.04.053

    authors: Minkoff H,Ecker J

    更新日期:2009-07-01 00:00:00