Multiple symmetric lipomatosis.

abstract：BACKGROUND:Major advances have been made in the understanding of the pathophysiology of psoriasis. OBJECTIVES:The authors review the role of interleukin (IL) 17 in the pathogenesis of psoriasis and provide updates on approved and investigational therapies targeting IL-17 and the IL-17 receptor. METHODS:A PubMed searc...

journal_title：Journal of cutaneous medicine and surgery

authors： AbuHilal M,Walsh S,Shear N

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The self-inflicted dermatoses such as acne excorieé and neurotic excoriations are often chronic, recurring, and resistant to standard dermatologic therapies. OBJECTIVE:We present a 28-year-old woman with longstanding acne excorieé, whose acne started at age 14 years and was followed by acne excorieé at age ...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta MA,Gupta AK

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Selective cyclooxygenase (COX) 2 nonsteroidal anti-inflammatory drugs (NSAIDs) have been associated with a general lower incidence of side effects compared with nonselective NSAIDs. Postmarketing information has highlighted the need to reassess the risk evaluation for specific organs, including the skin. OB...

journal_title：Journal of cutaneous medicine and surgery

authors： Atzori L,Pinna AL,Pau M,Aste N,Zucca M,Ferreli C

更新日期：2006-01-01 00:00:00

abstract：:The Maintenance of Certification (MOC) Program administered by the Royal College of Physicians and Surgeons applies to all Fellows of the Royal College including dermatologists. It is mandatory for those who wish to maintain their fellowship in the Royal College and can be critical for maintaining licensure requiremen...

journal_title：Journal of cutaneous medicine and surgery

authors： Rich P

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Moderate to severe chronic hand dermatitis (CHD) is not well controlled by current medical strategies; however, recent studies have shown significant improvement in patients treated with up to 6 months of oral alitretinoin (9-cis-retinoic acid). The results of longer-term continuous treatment are lacking. O...

journal_title：Journal of cutaneous medicine and surgery

authors： Gulliver WP,Baker KA

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder caused by loss-of-function mutation in the NF1 gene. Segmental or mosaic NF1 (MNF) is an uncommon presentation of the NF1 result of postzygotic mutations that present with subtle localised clinical findings. OBJECTIVES:Our study's objectives were t...

journal_title：Journal of cutaneous medicine and surgery

authors： Lara-Corrales I,Moazzami M,García-Romero MT,Pope E,Parkin P,Shugar A,Kannu P

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid (BP) is an autoimmune polymorphic skin disease characterized by erythematous papules and plaques and tense bullae. A skin biopsy for direct immunofluorescence (DIF) is used to detect autoantibodies and complement proteins. OBJECTIVE:We sought to determine which location would provide the ...

journal_title：Journal of cutaneous medicine and surgery

authors： Sladden C,Kirchhof MG,Crawford RI

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Sarcoidosis is a systemic granulomatous disease of unknown etiology that affects multiple organ systems, including the pulmonary, lymphatic, skeletal, and integumentary systems. Improved understanding of the intrinsic immunology and molecular biology in sarcoidosis can be applied to the treatment of this dis...

journal_title：Journal of cutaneous medicine and surgery

authors： Garcia-Zuazaga J,Korman NJ

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:It has been demonstrated that hypertrophic scar fibroblasts (HSFs) overexpress collagen messenger ribonucleic acid (mRNA) and protein, especially alpha1 collagen. Antisense nucleic acids are effective in inhibiting harmful or uncontrolled gene expression, suggesting that antisense ribonucleic acid (RNA) can ...

journal_title：Journal of cutaneous medicine and surgery

authors： Ju-Lin X,Shao-Hai Q,Tian-Zeng L,Chao-Quan L,Hou-Dong L,Ying-Bin X,Xu-Sheng L,Bin S,Hui-Zhen L,Yong H

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:pemphigoid gestationis is an autoimmune blistering disease affecting pregnant women. Treatment often consists of topical corticosteroids, oral antihistamines, and oral prednisone followed by immunosuppressants. Refractory cases in antepartum patients present a particular therapeutic challenge as the majority...

journal_title：Journal of cutaneous medicine and surgery

authors： Doiron P,Pratt M

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Patient nonattendance is a frequent occurrence in dermatology clinics, and our responsibility regarding the follow-up of these patients remains nebulous. OBJECTIVE:This study sought to evaluate the beliefs and practices of physicians at a university-affiliated medical dermatology clinic regarding patient no...

journal_title：Journal of cutaneous medicine and surgery

authors： Nasseri E,Bertrand J,Brassard D,Fortier-Riberdy G,Marcil I

更新日期：2012-03-01 00:00:00

abstract：:Lichen planus (LP) is a chronic inflammatory disorder that most commonly affects middle-aged individuals. LP involves the skin and/or mucous membranes, including oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. Linear LP, a rare distinct variant of LP, is characterised by pruritic eruption of lichen...

journal_title：Journal of cutaneous medicine and surgery

authors： Thomas MG,Betsy A

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Dabrafenib, a novel selective small-molecule inhibitor of BRAF, has been shown to increase overall survival in patients with unresectable metastatic melanoma harboring the BRAF V600E mutation. The development of resistance has led to combination therapy with selective MEK inhibitor trametinib. Compared with ...

journal_title：Journal of cutaneous medicine and surgery

authors： Lacroix JP,Wang B

更新日期：2017-01-01 00:00:00

abstract：:Atopic dermatitis (AD) is the most common pediatric chronic inflammatory skin disease in North America, often involving complex treatment regimens and impairing the quality of life of affected children and their families. Two topical calcineurin inhibitors (TCIs) have been available for the treatment of AD in pediatri...

journal_title：Journal of cutaneous medicine and surgery

authors： Fiorillo L,Marcoux D,Ramien M

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Hypohidrotic ectodermal dysplasia (HED) is a rare multisystem disorder that typically affects hair, teeth, nails, and sweat glands in combination with abnormalities of ectodermal originated tissues. OBJECTIVE:To raise the issue of whether heightened awareness is required in the follow-up of pigmented lesion...

journal_title：Journal of cutaneous medicine and surgery

authors： Gregoriou S,Rigopoulos D,Vergou T,Korfitis C,Menegakis G,Kontochristopoulos G

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVE:To better understand cutaneous photosensitivity reactions, a review of its etiologic factors, clinical characteristics, pathogenesis, and treatment modalities was undertaken. METHODS:Articles discussing the above aspects of phototoxic and photoallergic reactions were used to demonstrate what is currently kno...

journal_title：Journal of cutaneous medicine and surgery

authors： Lankerani L,Baron ED

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Topical minoxidil solution (TMS) is widely used for androgenetic alopecia (AGA), and this is the first report of a large safety trial. OBJECTIVES:The aim of the study was to evaluate the safety profile of TMS by comparing hospitalization and death rates among subjects using TMS with controls. Cardiovascular...

journal_title：Journal of cutaneous medicine and surgery

authors： Shapiro J

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Acne affects a large proportion of the Canadian population and has psychosocial and financial consequences. OBJECTIVE:We provide cost information for treatments recommended by the Canadian acne guidelines. METHODS:Highest level recommendations were selected for 3-month usage cost. RESULTS:Three-month esti...

journal_title：Journal of cutaneous medicine and surgery

authors： Czilli T,Tan J,Knezevic S,Peters C

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The development of knowledge concerning the role of sun exposure in causing skin cancer has been a gradual one. OBJECTIVE:This article reviews the article by Urbach who used manikin coated with an ultraviolet dosimeter to see exactly where on the head and neck the exposure was greatest. CONCLUSION:Urbach s...

journal_title：Journal of cutaneous medicine and surgery

authors： Jackson R

更新日期：1999-01-01 00:00:00

abstract：:Oral glucocorticoids are commonly used across every field of medicine; however, discontinuing them in patients can be challenging. The risk of acute adrenal crises secondary to glucocorticoid withdrawal can be fatal and arises from chronic suppression of the adrenal glands. Identifying risk factors for adrenal suppres...

journal_title：Journal of cutaneous medicine and surgery

authors： Nicholas MN,Li SK,Dytoc M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Genital herpes is a very common sexually transmitted disease. Safe and effective therapies are needed for patients with frequent recurrences. OBJECTIVE:The aim of our study was to determine the efficacy and safety of famciclovir for suppression of herpes simplex virus (HSV) infection in patients with histor...

journal_title：Journal of cutaneous medicine and surgery

authors： Tyring SK,Diaz-Mitoma F,Shafran SD,Locke LA,Sacks SL,Young CL

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Whereas several literature reviews have discussed the role of excipients in drug-related reactions, no article has focused specifically on those found in oral dermatologic medications. METHODS:The Compendium of Pharmaceuticals and Specialties (CPS) was used to reference the inert ingredients found in oral d...

journal_title：Journal of cutaneous medicine and surgery

authors： Noiles K,Vender R

更新日期：2010-05-01 00:00:00

abstract：:Larva currens is the cutaneous manifestation of human infection with the geotropic helminth Strongyloides stercoralis. Strongyloidiasis is a lifelong infection unless treated. A high index of suspicion is needed to prevent chronic symptoms of strongyloidiasis (eg, larva currens, eosinophilia, abdominal discomfort) and...

journal_title：Journal of cutaneous medicine and surgery

authors： Bailey KE,Danylo A,Boggild AK

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Darier's disease is an autosomal dominant genodermatosis typified by hyperkeratotic papules and plaques in a predominately seborrheic distribution. The vesiculo-bullous variant of Darier's disease is rare. Several previously reported cases have demonstrated clinical and microscopic features resembling famili...

journal_title：Journal of cutaneous medicine and surgery

authors： Klimas N,West C,Tarbox M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Elephantiasis is a well-known condition in dermatology usually affecting the legs and external genitalia. It is characterized by chronic inflammation and obstruction of the lymphatic channels and by hypertrophy of the skin and subcutaneous tissues. The etiology is either idiopathic or caused by a variety of ...

journal_title：Journal of cutaneous medicine and surgery

authors： Hanna D,Cloutier R,Lapointe R,Desgagné A

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Squamous cell carcinoma (SCC) is the second-most common form of non-melanoma skin cancer (NMSC). OBJECTIVE:To provide guidance to Canadian health care practitioners regarding management of SCCs. METHODS:Literature searches and development of graded recommendations were carried out as discussed in the accom...

journal_title：Journal of cutaneous medicine and surgery

authors： Sapijaszko M,Zloty D,Bourcier M,Poulin Y,Janiszewski P,Ashkenas J,Canadian Non-melanoma Skin Cancer Guidelines Committee.

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Crohn disease of the vulva is a rare disease that is difficult to diagnose. There are limited reports describing treatment of this condition. OBJECTIVE:To describe the diagnosis and treatment of a 16-year-old girl with Crohn disease of the vulva, without onset of intestinal symptoms. METHODS:Crohn disease ...

journal_title：Journal of cutaneous medicine and surgery

authors： Zhang AJ,Zhan SH,Chang H,Gao YQ,Li YQ

更新日期：2015-01-01 00:00:00

abstract：:Acne is a disease of the pilosebaceous units and these are mainly under hormonal control. In female patients, hormonal therapy is a unique opportunity for the treatment of acne. Several combined oral contraceptives (COCs), cyproterone acetate, spironolactone, flutamide, and others, have been tried for the control of a...

journal_title：Journal of cutaneous medicine and surgery

authors： Poulin Y

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Vemurafenib is an oral BRAF inhibitor recently approved for the treatment of metastatic melanoma. Patients treated with this medication have been reported to have the occurrence of squamous cell carcinoma (SCC) and/or actinic keratosis (AK). OBJECTIVE:We report the case of a patient treated with vemurafenib...

journal_title：Journal of cutaneous medicine and surgery

authors： Mays R,Curry J,Kim K,Tsai K,Arora A,Khan F,Ramirez-Fort M,Ciurea A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:An eczema action plan (EAP) is an individualized tool to help caregivers and patients self-manage eczema. While novel illustrated EAPs have been developed and validated, there is limited literature examining the value of EAPs from patient and caregiver perspectives. OBJECTIVES:The objective of this study wa...

journal_title：Journal of cutaneous medicine and surgery

authors： Shelley AJ,McDonald KA,McEvoy A,Sauder M,Kanigsberg N,Zemek R,Vaillancourt R,Pouliot A,Ramien ML

更新日期：2018-11-01 00:00:00