Attenuation of alpha1 collagen production with antisense ribonucleic acid in cultured hypertrophic scar fibroblasts.

abstract：:We report a case of an 17-year-old male with a drug reaction in the spectrum of Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), triggered by carbamazepine, who was succesfully treated with the combination of dexamethasone, cyclosporine, and etanercept. This triple therapy halted and prevented skin epi...

journal_title：Journal of cutaneous medicine and surgery

authors： Coulombe J,Belzile E,Duhamel A,Rault P,Buteau C,DeBruycker JJ,Bussières JF

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Diphenylcyclopropenone (DPCP) immunotherapy for viral warts has been used for many years, but no studies have analyzed the treatment effects of DPCP alone, without the use of conventional therapy before immunotherapy. OBJECTIVES:We evaluated clinical efficacy of DPCP monotherapy compared to cryotherapy and ...

journal_title：Journal of cutaneous medicine and surgery

authors： Park JY,Park BW,Cho EB,Park EJ,Kim KH,Kim KJ

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Sjögren syndrome (SS) is a chronic autoimmune inflammatory disease that involves primarily the exocrine glands, resulting in their functional impairment. SS typically presents as dry eyes (xerophthalmia) and dry mouth (xerostomia). This process can manifest either as the independent phenomenon of primary SS ...

journal_title：Journal of cutaneous medicine and surgery

authors： Kittridge A,Routhouska SB,Korman NJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Pemphigus vegetans is a rare variant of pemphigus vulgaris, comprising 1 to 2% of all pemphigus cases. Exposures to oral agents such as captopril and penicillamine and, less commonly, physical or chemical factors have been implicated in the development of pemphigus. METHODS:We report a 42-year-old white mal...

journal_title：Journal of cutaneous medicine and surgery

authors： Ngo JT,Trotter MJ,Robertson LH

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Dermoscopy has been shown to be a promising method to facilitate the diagnosis of lichen planus (LP) outside of China. OBJECTIVE:To investigate the spectrum of dermoscopic patterns in Chinese LP patients. METHODS:The clinical data and dermoscopic patterns of nine LP cases with a total of 43 lesions were ev...

journal_title：Journal of cutaneous medicine and surgery

authors： Tan C,Min ZS,Xue Y,Zhu WY

更新日期：2014-01-01 00:00:00

abstract：:Oral glucocorticoids are commonly used across every field of medicine; however, discontinuing them in patients can be challenging. The risk of acute adrenal crises secondary to glucocorticoid withdrawal can be fatal and arises from chronic suppression of the adrenal glands. Identifying risk factors for adrenal suppres...

journal_title：Journal of cutaneous medicine and surgery

authors： Nicholas MN,Li SK,Dytoc M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Dermatofibrosarcoma protuberans with fibrosarcomatous differentiation (DFSP-FS) is a rare variant of DFSP with a more aggressive clinical course, characterized by higher rates of local recurrence, metastasis, and death. METHODS:We conducted a clinicopathologic review of all DFSP-FS cases that occurred in Al...

journal_title：Journal of cutaneous medicine and surgery

authors： Kuzel P,Mahmood MN,Metelitsa AI,Salopek TG

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Darier's disease is an autosomal dominant genodermatosis typified by hyperkeratotic papules and plaques in a predominately seborrheic distribution. The vesiculo-bullous variant of Darier's disease is rare. Several previously reported cases have demonstrated clinical and microscopic features resembling famili...

journal_title：Journal of cutaneous medicine and surgery

authors： Klimas N,West C,Tarbox M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Alefacept (Amevive) is a fully human LFA-3/IgG1 fusion protein with a dual mechanism of action inhibiting T-cell activation and selectively reducing memory T cells. Alefacept is currently approved as a 12-week course of weekly 15 mg intramuscular (IM) injections for the treatment of adults with moderate to s...

journal_title：Journal of cutaneous medicine and surgery

authors： Moul DK,Routhouska SB,Korman NJ

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:The classification of many pigmented lesions is not well defined, and an association with melanoma has not been established. OBJECTIVE:To better define the spectrum of pigmented lesions (excluding common and dysplastic nevi) and explore links to melanoma. METHODS:Retrospective review of patients with total...

journal_title：Journal of cutaneous medicine and surgery

authors： Menon K,Dusza SW,Marghoob AA,Halpern AC,Nehal KS

更新日期：2006-03-01 00:00:00

abstract：:Acne is a disease of the pilosebaceous units and these are mainly under hormonal control. In female patients, hormonal therapy is a unique opportunity for the treatment of acne. Several combined oral contraceptives (COCs), cyproterone acetate, spironolactone, flutamide, and others, have been tried for the control of a...

journal_title：Journal of cutaneous medicine and surgery

authors： Poulin Y

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:In 1995, a Rosacea Awareness Program (RAP) was initiated in Canada to make available educational resources for physicians and rosacea patients. Material is in French or English, and is accessible though physician offices and by toll-free telephone. Information was communicated to the public via noncommercial...

journal_title：Journal of cutaneous medicine and surgery

authors： Shear NH,Levine C

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:PASI is an inadequate outcome measure for the assessment of psoriasis treatments. No currently used endpoints provide a benefit: risk assessment of treatment taking into consideration all available efficacy and safety data. OBJECTIVE:To propose a new outcome measure called "safe psoriasis control" (SPC), wh...

journal_title：Journal of cutaneous medicine and surgery

authors： Papp KA,Henninger E

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Laser epilation is now used widely as a clinical alternative to electrolysis for the removal of unwanted hair. All of the laser systems presently being used produce a reliable temporary hair loss by inducing telogen. Most of the published studies use follow-up periods of 6 months or less after the last treat...

journal_title：Journal of cutaneous medicine and surgery

authors： Laughlin SA,Dudley DK

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Plantar warts are typically resistant to treatment. In recent years, treatments have included administration of intralesional tuberculin; measles, mumps, rubella vaccine; and Candida albicans antigen immunotherapy. To the best of our knowledge, there are no reports of intralesional vitamin D administration f...

journal_title：Journal of cutaneous medicine and surgery

authors： Aktaş H,Ergin C,Demir B,Ekiz Ö

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Schnitzler syndrome (SS) is a rare autoinflammatory disorder characterized by a recurrent urticarial rash and a monoclonal immunoglobulin M gammopathy, as well as 2 of the following minor criteria: recurrent fever (>38°C), objective signs of abnormal bone remodeling, elevated C-reactive protein level or leuk...

journal_title：Journal of cutaneous medicine and surgery

authors： Urbanski M,Holfeld K,Milne A,Abbas M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Crohn disease of the vulva is a rare disease that is difficult to diagnose. There are limited reports describing treatment of this condition. OBJECTIVE:To describe the diagnosis and treatment of a 16-year-old girl with Crohn disease of the vulva, without onset of intestinal symptoms. METHODS:Crohn disease ...

journal_title：Journal of cutaneous medicine and surgery

authors： Zhang AJ,Zhan SH,Chang H,Gao YQ,Li YQ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Paget's disease is an extremely rare condition of the male breast that presents as an eczematous change of the nipple and areola. It is almost always associated with an underlying intraductal carcinoma. OBJECTIVE:A case of Paget's disease of the male breast with extension into adnexal structures is reported...

journal_title：Journal of cutaneous medicine and surgery

authors： Hayes R,Cummings B,Miller RA,Guha AK

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Indoor tanning (IT) in fitness facilities encourages a misleading positive relationship between tanning and health. While IT in Canadian fitness facilities has been studied, American literature regarding this topic is lacking. OBJECTIVES:The objective of this study is to evaluate availability, cost, reporte...

journal_title：Journal of cutaneous medicine and surgery

authors： Huang CM,Kirchhof MG

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Cutaneous T-cell lymphoma is a rare subtype of posttransplantation lymphoproliferative disease, with only 29 cases reported in the literature to date, the majority of which are post-renal transplantation. Only a few were reported after pancreas, heart, and bone marrow transplantation. There have been no repo...

journal_title：Journal of cutaneous medicine and surgery

authors： Al Ajroush N,Rafique Sheikh K,Kadry R,Almutawa A,Alfadley A

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Ear keloids continue to be a therapeutic challenge. OBJECTIVE:To evaluate the clinical success of a modified "oyster splint technique." METHODS:Ten patients with an ear keloid agreed to receive the compression therapy. After surgical removal, a compressive device made of acrylic resin was applied on top of...

journal_title：Journal of cutaneous medicine and surgery

authors： Hassel JC,Löser C,Koenen W,Kreuter A,Hassel AJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Epidermolysis bullosa acquisita (EBA) is a chronic subepidermal blistering disease that is frequently resistant to therapy. OBJECTIVE:A 58-year-old man who had a one-year history of a bullous eruption involving the hands, forearms, trunk, scalp, and oral mucosa. Histopathology revealed a subepidermal bulla,...

journal_title：Journal of cutaneous medicine and surgery

authors： Hughes AP,Callen JP

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Pustular psoriasis is an uncommon form of psoriasis that often affects areas of the hands and feet. It typically manifests as small pustules that develop within erythematous areas of the palms and soles. Infliximab, a tumor necrosis factor inhibitor, can be used to treat pustular psoriasis. Infliximab can al...

journal_title：Journal of cutaneous medicine and surgery

authors： English PL,Vender R

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:In addition to corticosteroids, there are increasing numbers of anti-inflammatory agents that specifically target bioactive lipids generated from arachidonic acid. Knowledge of the diverse mechanisms of action of these different bioactive lipids holds promise in the therapy of a wide spectrum of cutaneous an...

journal_title：Journal of cutaneous medicine and surgery

authors： Smith KJ,Skelton H

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Onychomycosis is a persistent fungal nail infection that is notoriously hard to treat. Approximately 20% to 25% of patients with onychomycosis do not respond to treatment, and 10% to 53% of patients relapse. As such, successful treatment is imperative for long-term disease management. OBJECTIVE:To identify ...

journal_title：Journal of cutaneous medicine and surgery

authors： Gupta AK,Cernea M,Foley KA

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Genital herpes is a very common sexually transmitted disease. Safe and effective therapies are needed for patients with frequent recurrences. OBJECTIVE:The aim of our study was to determine the efficacy and safety of famciclovir for suppression of herpes simplex virus (HSV) infection in patients with histor...

journal_title：Journal of cutaneous medicine and surgery

authors： Tyring SK,Diaz-Mitoma F,Shafran SD,Locke LA,Sacks SL,Young CL

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Vemurafenib is an oral BRAF inhibitor recently approved for the treatment of metastatic melanoma. Patients treated with this medication have been reported to have the occurrence of squamous cell carcinoma (SCC) and/or actinic keratosis (AK). OBJECTIVE:We report the case of a patient treated with vemurafenib...

journal_title：Journal of cutaneous medicine and surgery

authors： Mays R,Curry J,Kim K,Tsai K,Arora A,Khan F,Ramirez-Fort M,Ciurea A

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To better understand cutaneous photosensitivity reactions, a review of its etiologic factors, clinical characteristics, pathogenesis, and treatment modalities was undertaken. METHODS:Articles discussing the above aspects of phototoxic and photoallergic reactions were used to demonstrate what is currently kno...

journal_title：Journal of cutaneous medicine and surgery

authors： Lankerani L,Baron ED

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:The development of knowledge concerning the role of sun exposure in causing skin cancer has been a gradual one. OBJECTIVE:This article reviews the article by Urbach who used manikin coated with an ultraviolet dosimeter to see exactly where on the head and neck the exposure was greatest. CONCLUSION:Urbach s...

journal_title：Journal of cutaneous medicine and surgery

authors： Jackson R

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:In 1997, it was reported that a PTEN gene deletion, a common genetic mutation in Cowden's disease (CD), was identified in a patient with Bannayan-Riley-Ruvacalba (BRR), suggesting that the two diseases were allelic. However, the clinical overlap between the two diseases has largely remained unclear. OBJECTI...

journal_title：Journal of cutaneous medicine and surgery

authors： Blum RR,Rahimizadeh A,Kardon N,Lebwohl M,Wei H

更新日期：2001-05-01 00:00:00