Adverse cutaneous reactions to selective cyclooxygenase 2 inhibitors: experience of an Italian drug-surveillance center.

abstract：:The Maintenance of Certification (MOC) Program administered by the Royal College of Physicians and Surgeons applies to all Fellows of the Royal College including dermatologists. It is mandatory for those who wish to maintain their fellowship in the Royal College and can be critical for maintaining licensure requiremen...

journal_title：Journal of cutaneous medicine and surgery

authors： Rich P

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Calciphylaxis is a rare syndrome of vascular calcification with subsequent cutaneous and tissue necrosis. It usually manifests as a complication of end-stage renal failure, affecting 1 to 4% of long-term dialysis patients. Very exceptionally, it can occur without chronic renal failure. OBJECTIVE:The goal of...

journal_title：Journal of cutaneous medicine and surgery

authors： Stanciu M,Gagné-Henley A,Thérien G

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Sun-induced malignancies (basal cell and squamous cell carcinomas) are common in oculocutaneous albinism, however, the incidence of malignant melanoma is a topic of controversy. OBJECTIVE:We have reviewed the literature and report a case of a woman with oculocutaneous albinism with an amelanotic melanoma of...

journal_title：Journal of cutaneous medicine and surgery

authors： Streutker CJ,McCready D,Jimbow K,From L

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Dabrafenib, a novel selective small-molecule inhibitor of BRAF, has been shown to increase overall survival in patients with unresectable metastatic melanoma harboring the BRAF V600E mutation. The development of resistance has led to combination therapy with selective MEK inhibitor trametinib. Compared with ...

journal_title：Journal of cutaneous medicine and surgery

authors： Lacroix JP,Wang B

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Molluscum contagiosum is a viral infection of the skin that is widely considered to be a self-resolving disease that can be treated with benign neglect. However, the clinical reality is that the disease can vary widely by anatomic site and by recalcitrance to treatment and remains a significant cause of morb...

journal_title：Journal of cutaneous medicine and surgery

authors： Nguyen HP,Franz E,Stiegel KR,Hsu S,Tyring SK

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Plantar warts are typically resistant to treatment. In recent years, treatments have included administration of intralesional tuberculin; measles, mumps, rubella vaccine; and Candida albicans antigen immunotherapy. To the best of our knowledge, there are no reports of intralesional vitamin D administration f...

journal_title：Journal of cutaneous medicine and surgery

authors： Aktaş H,Ergin C,Demir B,Ekiz Ö

更新日期：2016-03-01 00:00:00

abstract：:Atopic dermatitis (AD) is the most common pediatric chronic inflammatory skin disease in North America, often involving complex treatment regimens and impairing the quality of life of affected children and their families. Two topical calcineurin inhibitors (TCIs) have been available for the treatment of AD in pediatri...

journal_title：Journal of cutaneous medicine and surgery

authors： Fiorillo L,Marcoux D,Ramien M

更新日期：2019-09-01 00:00:00

abstract：:Basal cell carcinomas (BCC) are the most frequent tumours in humans and normally appear in photoexposed areas of the skin. It is widely accepted that BCCs originate at follicular stem cells and consequently are very rare in nonhairy areas. Here, we report 4 cases of vulvar BCC, 3 of which were located in a vulvar semi...

journal_title：Journal of cutaneous medicine and surgery

authors： García-de-la-Fuente MR,Santacana M,Vilardell F,Pujol RM,Gari E,Casanova JM

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Mycobacterium marinum infections have been reported for over 50 years, mostly in association with trauma in the setting of water exposure. OBJECTIVE:The differential diagnosis for nodules in a sporotrichoid distribution with simultaneous bursitis is discussed. Mycobacterium marinum treatment regimens for sk...

journal_title：Journal of cutaneous medicine and surgery

authors： Saadatmand B,Poulton JK,Kauffman CL

更新日期：1999-04-01 00:00:00

abstract：:Actinic keratosis (AK), located on sun-exposed areas of the skin, is an increasing global health burden. Multiple ablative and topical treatment options are available to manage this disease; however, topical treatment options are receiving significant interest because AK is commonly associated with areas of substantia...

journal_title：Journal of cutaneous medicine and surgery

authors： Jorizzo JL

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:In 1995, a Rosacea Awareness Program (RAP) was initiated in Canada to make available educational resources for physicians and rosacea patients. Material is in French or English, and is accessible though physician offices and by toll-free telephone. Information was communicated to the public via noncommercial...

journal_title：Journal of cutaneous medicine and surgery

authors： Shear NH,Levine C

更新日期：1999-04-01 00:00:00

abstract：:Juvenile xanthogranuloma (JXG) is a member of the non-Langerhans cell group of proliferative disorders of mononuclear phagocytes. JXG is a benign tumour of histiocytic cells. Classic JXG is divided into 2 main clinical subtypes: dome-shaped papules (<0.5 cm) and single/multiple nodules (<2.0 cm). A rare variant is ref...

journal_title：Journal of cutaneous medicine and surgery

authors： Ladha MA,Haber RM

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Elastosis perforans serpiginosa (EPS) is a rare skin disease in which abnormal elastic tissue fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis via transepithelial elimination. It is characterized by an eruption of small grouped hyperkeratotic papules in a s...

journal_title：Journal of cutaneous medicine and surgery

authors： Humphrey S,Hemmati I,Randhawa R,Crawford RI,Hong CH

更新日期：2010-01-01 00:00:00

abstract：:The intention of the Summary Notes section is to provide the practitioner and trainee with a current, concise reference source to dermatologic diseases and to serve as a form of Continuing Medical Education. Each installment will deal with a specific disease. When included, the pretest questions indicate some of the a...

journal_title：Journal of cutaneous medicine and surgery

authors： Katz AM

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:A number of inflammatory and immune diseases are associated with vascular changes. Psoriasis, as an example, is a common inflammatory skin disease with dilation of capillaries as an early histological change. In more developed psoriatic lesions there is proliferation of blood vessels and neovascularization. ...

journal_title：Journal of cutaneous medicine and surgery

authors： Dupont E,Savard PE,Jourdain C,Juneau C,Thibodeau A,Ross N,Marenus K,Maes DH,Pelletier G,Sauder DN

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:In addition to corticosteroids, there are increasing numbers of anti-inflammatory agents that specifically target bioactive lipids generated from arachidonic acid. Knowledge of the diverse mechanisms of action of these different bioactive lipids holds promise in the therapy of a wide spectrum of cutaneous an...

journal_title：Journal of cutaneous medicine and surgery

authors： Smith KJ,Skelton H

更新日期：2002-05-01 00:00:00

abstract：:Oral glucocorticoids are commonly used across every field of medicine; however, discontinuing them in patients can be challenging. The risk of acute adrenal crises secondary to glucocorticoid withdrawal can be fatal and arises from chronic suppression of the adrenal glands. Identifying risk factors for adrenal suppres...

journal_title：Journal of cutaneous medicine and surgery

authors： Nicholas MN,Li SK,Dytoc M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Hybrid skin adnexal tumors are common, and spiradenocylindroma is well described. OBJECTIVE:However, malignant transformation in this setting is infrequent, especially resemblance to lymphoepithelioma-like carcinoma of skin, which is not associated with Epstein-Barr virus. METHODS:A 65-year-old female pres...

journal_title：Journal of cutaneous medicine and surgery

authors： Chetty R,Perez-Ordonez B,Gilbert R,Pagedar NA,Waldron J,Ghazarian D

更新日期：2009-07-01 00:00:00

abstract：:Genital ulcer disease can be caused by a wide variety of sources. Most commonly, genital ulcer disease is grouped into infectious and noninfectious causes. HSV, syphilis, lymphogranuloma venereum, and chancroid represent some common infectious ulcers. Noninfectious causes on the other hand can be inflammatory, noninfl...

journal_title：Journal of cutaneous medicine and surgery

authors： Maliyar K,Mufti A,Syed M,Selk A,Dutil M,Bunce PE,Alavi A

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Schnitzler syndrome (SS) is a rare autoinflammatory disorder characterized by a recurrent urticarial rash and a monoclonal immunoglobulin M gammopathy, as well as 2 of the following minor criteria: recurrent fever (>38°C), objective signs of abnormal bone remodeling, elevated C-reactive protein level or leuk...

journal_title：Journal of cutaneous medicine and surgery

authors： Urbanski M,Holfeld K,Milne A,Abbas M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The onychodystrophies associated with Sézary syndrome (SzS) have rarely been described in the literature. We performed a retrospective analysis of SzS patients at a single institution and compared our data with previous publications. OBJECTIVES:The objectives of this study were to identify and describe the ...

journal_title：Journal of cutaneous medicine and surgery

authors： Damasco FM,Geskin LJ,Akilov OE

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Diphenylcyclopropenone (DPCP) immunotherapy for viral warts has been used for many years, but no studies have analyzed the treatment effects of DPCP alone, without the use of conventional therapy before immunotherapy. OBJECTIVES:We evaluated clinical efficacy of DPCP monotherapy compared to cryotherapy and ...

journal_title：Journal of cutaneous medicine and surgery

authors： Park JY,Park BW,Cho EB,Park EJ,Kim KH,Kim KJ

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Vemurafenib is an oral BRAF inhibitor recently approved for the treatment of metastatic melanoma. Patients treated with this medication have been reported to have the occurrence of squamous cell carcinoma (SCC) and/or actinic keratosis (AK). OBJECTIVE:We report the case of a patient treated with vemurafenib...

journal_title：Journal of cutaneous medicine and surgery

authors： Mays R,Curry J,Kim K,Tsai K,Arora A,Khan F,Ramirez-Fort M,Ciurea A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Systemic therapy for atopic dermatitis (AD) has been challenging with limited safe and efficacious long-term treatment options. In 2017, dupilumab was approved in the United States, Europe, and Canada as the first targeted therapy for patients with moderate-to-severe AD. Despite promising efficacy and safety...

journal_title：Journal of cutaneous medicine and surgery

authors： Jo CE,Georgakopoulos JR,Ladda M,Ighani A,Mufti A,Drucker AM,Piguet V,Yeung J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Direct-acting antivirals (DAAs) are known to present with additional dermatological events over pegylated-interferon/ribavirin (Peg-IFN/RBV). OBJECTIVE:A systematic review and meta-analysis was conducted to assess the incidence/risk of cutaneous adverse events (AEs) for simeprevir, sofosbuvir, ABT450/r-ombi...

journal_title：Journal of cutaneous medicine and surgery

authors： Patel P,Malik K,Krishnamurthy K

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Alefacept (Amevive) is a fully human LFA-3/IgG1 fusion protein with a dual mechanism of action inhibiting T-cell activation and selectively reducing memory T cells. Alefacept is currently approved as a 12-week course of weekly 15 mg intramuscular (IM) injections for the treatment of adults with moderate to s...

journal_title：Journal of cutaneous medicine and surgery

authors： Moul DK,Routhouska SB,Korman NJ

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Informed shared decision making is a mutual process engaging both doctor and patient and informed by best medical evidence and patient values and preferences. OBJECTIVE:Our aim was to identify the needs of psoriasis patients in decisions on selecting treatment. METHODS:Psoriasis subjects participated in an...

journal_title：Journal of cutaneous medicine and surgery

authors： Tan J,Stacey D,Fung K,Barankin B,Bissonnette R,Gulliver W,Lui H,Shear N,Jackson C,Zhang X

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Several clinical trials have established the benefit of using a topical corticosteroid in conjunction with tazarotene gel in the treatment of plaque psoriasis. However, there is little information comparing the relative benefits of different corticosteroids, or different formulations of corticosteroids, when...

journal_title：Journal of cutaneous medicine and surgery

authors： Green L,Sadoff W

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Although methotrexate is a highly effective treatment for psoriasis, nausea and vomiting may be dose-limiting side effects. Various approaches have been used to improve the tolerability of methotrexate therapy, including changing the dose or form of administration of the methotrexate or concomitant administr...

journal_title：Journal of cutaneous medicine and surgery

authors： Wilson JK,Phelps KC,Feldman SR

更新日期：2002-11-01 00:00:00

abstract：:The primary goal of treatment for external genital warts (EGWs) is to eradicate visible lesions and address symptoms that may accompany them, but it does not address the underlying virus. Left untreated, warts may grow, remain the same, or spontaneously regress as a result of being cleared by the immune system. Howeve...

journal_title：Journal of cutaneous medicine and surgery

authors： Vender R,Bourcier M,Bhatia N,Lynde C

更新日期：2013-12-01 00:00:00