PROX1 is a predictor of survival for gliomas WHO grade II.

abstract：:Two meta-analyses were conducted to quantify the benefit of combining alpha-IFN to 5FU in advanced colorectal cancer in terms of tumour response and survival. Analyses were based on a total of 3254 individual patient data provided by principal investigators of each trial. The meta-analysis of 5FU +/- LV vs. 5FU +/- LV...

journal_title：British journal of cancer

authors： Thirion P,Piedbois P,Buyse M,O'Dwyer PJ,Cunningham D,Man A,Greco FA,Colucci G,Köhne CH,Di Constanzo F,Piga A,Palmeri S,Dufour P,Cassano A,Pajkos G,Pensel RA,Aykan NF,Marsh J,Seymour MT,Meta-Analysis Group in Cancer.

更新日期：2001-03-02 00:00:00

abstract：:Question prompt lists (QPLs) have been shown to be an inexpensive and effective communication tool for patients in oncology consultations. We aimed to develop and pilot a QPL for palliative care (PC) patients. In order to identify suitable questions for inclusion in the QPL, we conducted focus groups and individual in...

journal_title：British journal of cancer

authors： Clayton J,Butow P,Tattersall M,Chye R,Noel M,Davis JM,Glare P

更新日期：2003-12-01 00:00:00

abstract：:In the early period following radical hepatectomy for hepatoma, recurrences in the remaining liver are frequently found. In regenerating liver, implantation and growth of tumour cells released into the portal system during surgical treatment might be promoted. We examined the relationship between liver regeneration an...

journal_title：British journal of cancer

authors： Mizutani J,Hiraoka T,Yamashita R,Miyauchi Y

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:We performed a cross-sectional study in Indonesia to evaluate the performance of a single-visit approach of cervical cancer screening, using visual inspection with acetic acid (VIA), histology and cryotherapy in low-resource settings. METHODS:Women having limited access to health-care facilities were screen...

journal_title：British journal of cancer

authors： Vet JN,Kooijman JL,Henderson FC,Aziz FM,Purwoto G,Susanto H,Surya IG,Budiningsih S,Cornain S,Fleuren GJ,Trimbos JB,Peters AA

更新日期：2012-08-21 00:00:00

abstract：:The efficacy of high-dose chemotherapy (HDC) and circulating progenitor cell (CPC) transplantation in metastatic breast cancer (MBC) relies mainly on giving this treatment after a response to conventional induction chemotherapy has been achieved. For this reason an optimal mobilization regimen should be therapeuticall...

journal_title：British journal of cancer

authors： Pedrazzoli P,Perotti C,Da Prada GA,Bertolini F,Gibelli N,Torretta L,Battaglia M,Pavesi L,Preti P,Salvaneschi L,Robustelli della Cuna G

更新日期：1997-01-01 00:00:00

abstract：:Chromosome 9p21 gene copy number in Ewing's sarcoma family of tumour (ESFT) cell lines and primary ESFT has been evaluated using Multiplex Ligation-dependent probe amplification, and the clinical significance of CDKN2A loss and p16/p14(ARF) expression investigated. Homozygous deletion of CDKN2A was identified in 4/9 (...

journal_title：British journal of cancer

authors： Brownhill SC,Taylor C,Burchill SA

更新日期：2007-06-18 00:00:00

abstract：:This study reports on the frequency and disease association pattern of a number of gene rearrangements in a large panel of lymphoid tumours (n = 94). We detected the t(11;14) translocation, involving rearrangement of the BCL-1 locus, in 60% of mantle cell lymphomas. The BCL-2 gene, located at band 18q21, was rearrange...

journal_title：British journal of cancer

authors： Butler M,Corbally N,Dervan PA,Carney DN

更新日期：1997-01-01 00:00:00

abstract：:Raised risks of several cancers have been found in patients with type II diabetes, but there are few data on cancer risk in type I diabetes. We conducted a cohort study of 28 900 UK patients with insulin-treated diabetes followed for 520 517 person-years, and compared their cancer incidence and mortality with national...

journal_title：British journal of cancer

authors： Swerdlow AJ,Laing SP,Qiao Z,Slater SD,Burden AC,Botha JL,Waugh NR,Morris AD,Gatling W,Gale EA,Patterson CC,Keen H

更新日期：2005-06-06 00:00:00

abstract：:The interaction between laminin and the oncoprotein encoded by the c-erbB-2 oncogene was studied in vitro and in vivo in human breast carcinomas. In vitro analysis of breast carcinoma cell lines overexpressing p185HER2 revealed that laminin, but not fibronectin, induced tyrosine phosphorylation and down-modulation of ...

journal_title：British journal of cancer

authors： Tagliabue E,Ardini E,Pellegrini R,Campiglio M,Bufalino R,Jeschke M,Groner B,Colnaghi MI,Ménard S

更新日期：1996-11-01 00:00:00

abstract：:A standardised, effective systemic therapy for metastatic neuroendocrine tumours (NETs) has not been established to date. We reviewed the management of 15 patients with inoperable, metastatic NET treated systematically with a combination chemotherapy regimen of infusional 5-fluorouracil, folinic acid and streptozocin....

journal_title：British journal of cancer

authors： Gonzalez MA,Biswas S,Clifton L,Corrie PG

更新日期：2003-08-04 00:00:00

abstract：BACKGROUND:A combination of S-1 and cisplatin has been shown to be effective with acceptable safety for the first-line treatment of far-advanced gastric cancer in Japan. This is the first randomised phase II trial to compare S-1+paclitaxel with S-1+cisplatin in this setting. METHODS:Patients with unresectable and/or r...

journal_title：British journal of cancer

authors： Mochiki E,Ogata K,Ohno T,Toyomasu Y,Haga N,Fukai Y,Aihara R,Ando H,Uchida N,Asao T,Kuwano H,North Kanto Gastric Cancer Study Group.

更新日期：2012-06-26 00:00:00

abstract：:The blood-brain barrier is a major obstacle for the chemotherapeutic drugs to effectively reach primary or secondary brain tumours. Stealth liposomal drugs are highly accumulated in tumoural tissues. In the present study we investigated the relative accumulation of(99m)Tc-DTPA radiolabelled stealth liposomal doxorubic...

journal_title：British journal of cancer

authors： Koukourakis MI,Koukouraki S,Fezoulidis I,Kelekis N,Kyrias G,Archimandritis S,Karkavitsas N

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Osteosarcoma (OS) is the most common primary bone tumour in children and adolescents. Patients who respond poorly to chemotherapy have a higher risk of metastatic disease and 5-year survival rates of only 10-20%. Therefore, identifying molecular targets that are specific for OS, or more specifically, metasta...

journal_title：British journal of cancer

authors： Endo-Munoz L,Cumming A,Sommerville S,Dickinson I,Saunders NA

更新日期：2010-06-29 00:00:00

abstract：BACKGROUND:CA-125 as a tumour progression criterion in relapsing ovarian cancer (ROC) trials remains controversial. CALYPSO is a large randomised trial incorporating CA-125 (GCIG criteria) and symptomatic deterioration in addition to Response Evaluation Criteria in Solid Tumours (RECIST) criteria (radiological) to dete...

journal_title：British journal of cancer

authors： Alexandre J,Brown C,Coeffic D,Raban N,Pfisterer J,Mäenpää J,Chalchal H,Fitzharris B,Volgger B,Vergote I,Pisano C,Ferrero A,Pujade-Lauraine E

更新日期：2012-02-14 00:00:00

abstract：BACKGROUND:To document the effect of bivalent HPV immunisation on cervical cytology as a screening test and assess the implications of any change, using a retrospective analysis of routinely collected data from the Scottish Cervical Screening Programme (SCSP). METHODS:Data were extracted from the Scottish Cervical Cal...

journal_title：British journal of cancer

authors： Palmer TJ,McFadden M,Pollock KG,Kavanagh K,Cuschieri K,Cruickshank M,Cotton S,Nicoll S,Robertson C

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Cancer incidence is increasing in the United Kingdom, as well as on a global basis. Biochemical parameters, such as C-reactive protein and albumin (combined to form the modified Glasgow Prognostic Score, mGPS), alkaline phosphatase (Alk phos), gamma-glutamyl transferase (GGT) and serum calcium have been repo...

journal_title：British journal of cancer

authors： Proctor MJ,Talwar D,Balmar SM,O'Reilly DS,Foulis AK,Horgan PG,Morrison DS,McMillan DC

更新日期：2010-09-07 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus and high total cholesterol and triglycerides are known to be associated with increased colorectal cancer risk for the general population. These associations are unknown for people with a germline DNA mismatch repair gene mutation (Lynch syndrome), who are at high risk of colorectal c...

journal_title：British journal of cancer

authors： Dashti SG,Li WY,Buchanan DD,Clendenning M,Rosty C,Winship IM,Macrae FA,Giles GG,Hardikar S,Hua X,Thibodeau SN,Figueiredo JC,Casey G,Haile RW,Gallinger S,Le Marchand L,Newcomb PA,Potter JD,Lindor NM,Hopper JL,Jenki

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:We assessed the association between symptoms reported at breast cancer screening visits and interval cancers (ICs) in a prospective manner. METHODS:This population-based matched cohort study uses data of the Finnish National Breast Cancer Screening Programme that invites women aged 50-69 years old during 19...

journal_title：British journal of cancer

authors： Singh D,Miettinen J,Duffy S,Malila N,Pitkäniemi J,Anttila A

更新日期：2018-11-01 00:00:00

abstract：:The radiosensitizing activity of S-nitroso-N-acetylpenicillamine (SNAP), a nitric oxide (NO) donor, was assessed in a model of non-metabolic hypoxia achieved in an atmosphere of 95% nitrogen-5% carbon dioxide. A 10 min preincubation of hypoxic EMT-6 cells (10 x 10(6) ml(-1)) with 0.1 and 1 mM SNAP before radiation res...

journal_title：British journal of cancer

authors： Janssens MY,Verovski VN,Van den Berge DL,Monsaert C,Storme GA

更新日期：1999-03-01 00:00:00

abstract：:Decreased accumulation of the fluorescent dye BCECF [2', 7'-bis-(2-carboxyethyl)-5-(6)- carboxyfluorescein] characterized murine and human multidrug-resistant cell lines overexpressing the multidrug resistance protein (MRP). Indomethacin (10 microM), a known cyclo-oxygenase and glutathione-S-transferase inhibitor as w...

journal_title：British journal of cancer

authors： Draper MP,Martell RL,Levy SB

更新日期：1997-01-01 00:00:00

abstract：:This corrects the article DOI: 10.1038/bjc.2017.85. ...

journal_title：British journal of cancer

authors： Linton A,Cheng YY,Griggs K,Schedlich L,Kirschner MB,Gattani S,Srikaran S,Chuan-Hao Kao S,McCaughan BC,Klebe S,van Zandwijk N,Reid G

更新日期：2018-03-20 00:00:00

abstract：BACKGROUND:Progression-free survival (PFS) is a surrogate endpoint widely used for overall survival (OS) in oncology. Validation of PFS as a surrogate must be done for each indication and each intervention. We aimed to identify all studies evaluating the validity of PFS as a surrogate for OS in oncology, and to describ...

journal_title：British journal of cancer

authors： Belin L,Tan A,De Rycke Y,Dechartres A

更新日期：2020-05-01 00:00:00

abstract：:When assessing the value of a particular treatment, it is important to consider the impact it may have on the quality of life of those being treated. This is particularly so for cancer patients, whose life expectancy may be short. Patients with advanced colorectal cancer who participated in two international comparati...

journal_title：British journal of cancer

authors： Anderson H,Palmer MK

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Mechanisms that increase resistance to apoptosis help promote cellular transformation. Cancer cells have deregulated apoptotic pathways, where increased expression and stability of anti-apoptotic proteins Mcl-1 and Bcl-2 increases resistance to apoptosis. Pathways that increase the stability of proteins in c...

journal_title：British journal of cancer

authors： Pervin S,Tran A,Tran L,Urman R,Braga M,Chaudhuri G,Singh R

更新日期：2011-07-26 00:00:00

abstract：:Oestrogen receptor alpha (ER-alpha) gene has two specific promoters, distal (P0) and proximal (P1), which induce almost identical transcripts in size due to different splicing. We examined the methylation at both promoter regions of the ER-alpha gene using HpaII, a methylation-sensitive restriction enzyme, prior to po...

journal_title：British journal of cancer

authors： Iwase H,Omoto Y,Iwata H,Toyama T,Hara Y,Ando Y,Ito Y,Fujii Y,Kobayashi S

更新日期：1999-08-01 00:00:00

abstract：:Maturation of monocytes into macrophages in vitro has been assayed by a quantitative microtitre assay in patients with squamous-cell carcinoma of the lung. Monocyte maturation in autologous serum was significantly depressed in patients with both limited and extensive disease compared with normal controls, patients wit...

journal_title：British journal of cancer

authors： Dent RG,Cole P

更新日期：1981-04-01 00:00:00

abstract：:The haemodynamics of the uterine arteries and myometrium were assessed using Doppler ultrasound in forty consecutive patients requiring treatment for invasive mole and choriocarcinoma. The investigations were performed prior to the commencement of chemotherapy and the subjects followed prospectively. The Doppler wavef...

journal_title：British journal of cancer

authors： Long MG,Boultbee JE,Langley R,Newlands ES,Begent RH,Bagshawe KD

更新日期：1992-11-01 00:00:00

abstract：:The expression of peroxisome proliferator-activated receptor (PPAR)gamma in thyroid neoplasias and in normal thyroid (NT) tissues has not been fully investigated. The objectives of the present work were: to study and compare the relative expression of PPARgamma in normal, benign and malignant thyroid tissues and to co...

journal_title：British journal of cancer

authors： Marques AR,Espadinha C,Frias MJ,Roque L,Catarino AL,Sobrinho LG,Leite V

更新日期：2004-08-16 00:00:00

abstract：:The 5T4 oncofetal antigen is a 72 kDa glycoprotein defined by a monoclonal antibody raised against human placental trophoblast and is expressed in many different carcinomas but detected only at low levels in some normal epithelia. Immunohistochemical analysis of the patterns of expression in colorectal carcinomas has ...

journal_title：British journal of cancer

authors： Starzynska T,Marsh PJ,Schofield PF,Roberts SA,Myers KA,Stern PL

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Liver metastases present with distinct histopathological growth patterns (HGPs), including the desmoplastic, pushing and replacement HGPs and two rarer HGPs. The HGPs are defined owing to the distinct interface between the cancer cells and the adjacent normal liver parenchyma that is present in each pattern ...

journal_title：British journal of cancer

authors： van Dam PJ,van der Stok EP,Teuwen LA,Van den Eynden GG,Illemann M,Frentzas S,Majeed AW,Eefsen RL,Coebergh van den Braak RRJ,Lazaris A,Fernandez MC,Galjart B,Laerum OD,Rayes R,Grünhagen DJ,Van de Paer M,Sucaet Y,Mudhar H

更新日期：2017-11-07 00:00:00