Abstract:
BACKGROUND:Calcineurin inhibitor cyclosporine A (CsA) is a potent immunosuppressive agent. The side effects of CsA include nephrotoxicity, hypertension, hypertrichosis, infection, hyperpotassemia, and, to a lower extent, neuropathy. OBJECTIVES:In this case report, we aimed to present a renal transplant patient with polyneuropathy (PNP) due to the use of CsA and with improvement when switched to rapamycin. METHODS:In electromyography, axonal sensory PNP was detected. CsA was stopped and rapamycin was begun. RESULTS:His complaints rapidly improved after using rapamycin. CONCLUSIONS:Patients using CsA should be closely monitored for peripheral neuropathy and in case of toxicity, alternative immunosuppressive agents should be considered.
journal_name
Ren Failjournal_title
Renal failureauthors
Sayin R,Soyoral YU,Erkoc Rdoi
10.3109/0886022X.2011.573893subject
Has Abstractpub_date
2011-01-01 00:00:00pages
528-30issue
5eissn
0886-022Xissn
1525-6049journal_volume
33pub_type
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