Polyneuropathy due to cyclosporine A in patients with renal transplantation: a case report.

Abstract:

BACKGROUND:Calcineurin inhibitor cyclosporine A (CsA) is a potent immunosuppressive agent. The side effects of CsA include nephrotoxicity, hypertension, hypertrichosis, infection, hyperpotassemia, and, to a lower extent, neuropathy. OBJECTIVES:In this case report, we aimed to present a renal transplant patient with polyneuropathy (PNP) due to the use of CsA and with improvement when switched to rapamycin. METHODS:In electromyography, axonal sensory PNP was detected. CsA was stopped and rapamycin was begun. RESULTS:His complaints rapidly improved after using rapamycin. CONCLUSIONS:Patients using CsA should be closely monitored for peripheral neuropathy and in case of toxicity, alternative immunosuppressive agents should be considered.

journal_name

Ren Fail

journal_title

Renal failure

authors

Sayin R,Soyoral YU,Erkoc R

doi

10.3109/0886022X.2011.573893

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

528-30

issue

5

eissn

0886-022X

issn

1525-6049

journal_volume

33

pub_type

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