NaOH-induced Crohn's colitis in rats: a novel experimental model.

abstract：:The 1993 Milwaukee Cryptosporidium outbreak posed several questions regarding appropriate management and prognosis of inflammatory bowel disease patients acutely infected with this organism. We prospectively identified and monitored 12 patients with stable ulcerative colitis or Crohn's disease who suffered abrupt clin...

journal_title：Digestive diseases and sciences

authors： Manthey MW,Ross AB,Soergel KH

更新日期：1997-08-01 00:00:00

abstract：:We compared changes in gastric mucosal blood flow (GMBF) and left gastric artery blood flow (LGABF) in response to pharmacological, physiological, and pathological stimuli. GMBF and LGABF were measured by the hydrogen gas clearance and perivascular ultrasonic transit time techniques, respectively, under baseline condi...

journal_title：Digestive diseases and sciences

authors： Méndez A,Casadevall M,Wachter CH,Elizalde JI,Del Rivero M,Heinemann A,Holzer P,Quintero E,Piqué JM

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Corticosteroids and pentoxifylline reduce short-term mortality in severe alcoholic hepatitis (SAH), but not to the extent desired. Combining both drugs may lead to better survival, but has not yet been studied. AIM:To compare the efficacy of corticosteroids plus pentoxifylline with that of corticosteroids a...

journal_title：Digestive diseases and sciences

authors： Sidhu SS,Goyal O,Singla P,Gupta D,Sood A,Chhina RS,Soni RK

更新日期：2012-06-01 00:00:00

abstract：:We report a case of localized jejunal amyloidosis occurring in a 74-year-old man who experienced an episode of digestive bleeding while he was receiving oral anticoagulation. It illustrates a rare entity, characterized by an endoscopic aspect of polypoid, pseudotumoral formations. Histologically, submucosal connective...

journal_title：Digestive diseases and sciences

authors： Peny MO,Debongnie JC,Haot J,Van Gossum A

更新日期：2000-09-01 00:00:00

abstract：:Our objective was to study the predictive value of the family history in the initial diagnosis of hereditary hemochromatosis. Sixty five hemochromatosis proband patients and 66 control patients with chronic liver disease were assessed for a family history of hemochromatosis, cirrhosis, diabetes, and arthritis. There w...

journal_title：Digestive diseases and sciences

authors： Assy N,Adams PC

更新日期：1997-06-01 00:00:00

abstract：:Our objective was to determine whether there are dominating racial differences in patient preferences for surgery that may explain the disparities in proctocolectomy utilization between African Americans (AA) and whites. We used the time trade-off technique to measure health preferences for undergoing ileal pouch anal...

journal_title：Digestive diseases and sciences

authors： Nguyen GC,Tuskey A,Bayless TM,LaVeist TA,Brant SR

更新日期：2008-03-01 00:00:00

abstract：:Chronic diarrhea and colitis are common in patients positive for human immunodeficiency virus (HIV) under highly active antiretroviral treatment (HAART). This prospective double-blind study explores the effect of mesalamine vs. placebo in HIV-positive patients. Thirteen HIV-infected patients with noninfectious chronic...

journal_title：Digestive diseases and sciences

authors： Rodríguez-Torres M,Rodríguez-Orengo JF,Ríos-Bedoya CF,Fernández-Carbia A,Salgado-Mercado R,Marxuach-Cuétara AM

更新日期：2006-01-01 00:00:00

abstract：:Food allergy, a commonly increasing problem worldwide, defined as an adverse immune response to food. A variety of immune-related effector cells such as mast cells, eosinophils, neutrophils, and T cells are involved in food-related allergic responses categorized as IgE mediated, non-IgE mediated, and mixed (IgE and no...

journal_title：Digestive diseases and sciences

authors： Manohar M,Verma AK,Upparahalli Venkateshaiah S,Goyal H,Mishra A

更新日期：2017-12-01 00:00:00

abstract：:Our objective was to investigate the expression of HMGA1 mRNA and protein in hepatocellular carcinoma (HCC) and the correlation between its expression and clinical pathological characteristics and prognosis. HMGA1 expression was determined at both the mRNA level and the protein level in 30 HCC tissues and their corres...

journal_title：Digestive diseases and sciences

authors： Chang ZG,Yang LY,Wang W,Peng JX,Huang GW,Tao YM,Ding X

更新日期：2005-10-01 00:00:00

abstract：:Our purpose was to observe the effects of sodium phosphate (NaP) colonoscopy preparation on serum electrolytes, phosphate, and calcium and to identify factors associated with any adverse effects. In an unselected group of 100 consecutive patients attending for out patient colonoscopy, 45% of patients had raised serum ...

journal_title：Digestive diseases and sciences

authors： Ainley EJ,Winwood PJ,Begley JP

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:The endoscopic detection of esophageal cancer is suboptimal in both patients referred with dyspeptic symptoms and those enrolled in Barrett's surveillance programs. MCM5 expression in cells collected from gastric fluid may be correlated with the presence of dysplasia or adenocarcinoma. Analysis of this bioma...

journal_title：Digestive diseases and sciences

authors： Everson M,Magee C,Alzoubaidi D,Brogden S,Graham D,Lovat LB,Novelli M,Haidry R

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:The Child-Turcotte-Pugh (CTP) score is a widely used and validated predictor of long-term survival in cirrhosis. However, the cutpoints for stratifying laboratory variables in CTP have never been validated. OBJECTIVE:The objective of this study was to identify evidence-based cutpoints for the CTP laboratory...

journal_title：Digestive diseases and sciences

authors： Kaplan DE,Dai F,Skanderson M,Aytaman A,Baytarian M,D'Addeo K,Fox R,Hunt K,Knott A,Mehta R,Pedrosa M,Pocha C,Valderrama A,Taddei T,VOCAL Study Group.

更新日期：2016-11-01 00:00:00

abstract：:The effect on the mucosa of sodium nitrite that enters the colon from the ileum or transmucosally from the circulation is unknown. Isolated colonic mucosal cells and Roux-en-Y colostomies were used to test whether high doses of sodium nitrite (5-40 mM) had any harmful histological or inhibitory metabolic actions on th...

journal_title：Digestive diseases and sciences

authors： Roediger WE,Radcliffe BC,Deakin EJ,Nance SH

更新日期：1986-05-01 00:00:00

abstract：:The role of HBV precore mutations in the spontaneous reactivation of chronic hepatitis B (CHB) is currently unknown. We studied 10 patients with CHB; five were HBeAg+ (group I) and five were anti-HBe+ (group II). All 10 had spontaneous reactivation of CHB as defined by the appearance of clinical symptoms along with an...

journal_title：Digestive diseases and sciences

authors： Laskus T,Rakela J,Tong MJ,Persing DH

更新日期：1994-09-01 00:00:00

abstract：:Capsaicin-sensitive afferent nerves (CSANs) are involved in the protection of gastric mucosa. To clarify the role of CSANs in human Helicobacter pylori-negative or -positive chronic gastritis, after bacterium detection by rapid urease test, (14)C urea breath test, and specific histological staining, the immunodistribu...

journal_title：Digestive diseases and sciences

authors： Dömötör A,Kereskay L,Szekeres G,Hunyady B,Szolcsányi J,Mózsik G

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Gastric intestinal metaplasia (GIM) is an accepted pathologic precursor to gastric adenocarcinoma (GAC). While surveillance of GIM in Europe and Asia is common, only limited recommendations related to endoscopic surveillance of GIM exist in the United States. AIM:To understand the clinical practice patterns...

journal_title：Digestive diseases and sciences

authors： Vance RB Jr,Kubiliun N,Dunbar KB

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Intraductal ultrasonography (IDUS) is a useful procedure for diagnosing microlithiasis in the bile duct but it is not easy to differentiate between tiny echogenicity and real microlithiasis. We compared the echogenicity seen on IDUS and the findings of bile microscopy (BM) of bile that was collected in the c...

journal_title：Digestive diseases and sciences

authors： Kim BJ,Kang P,Lee JK,Sinn DH,Lee KH,Lee KT,Rhee JC,Lim JH

更新日期：2010-03-01 00:00:00

abstract：:In enriched canine parietal cell preparations, misoprostol, an analog of prostaglandin E1 methyl ester, was rapidly deesterified to misoprostol free acid. Under this circumstance, misoprostol and misoprostol free acid exhibited equal antisecretory potency against histamine-stimulated acid secretion and bound equally w...

journal_title：Digestive diseases and sciences

authors： Tsai BS,Kessler LK,Stolzenbach J,Schoenhard G,Bauer RF

更新日期：1991-05-01 00:00:00

abstract：:The effect of smoking on interdigestive gastrointestinal motility is little studied but may play a role in gastrointestinal morbidity. We studied gastroduodenal motility in 10 volunteers (five smokers and five nonsmokers) using a water-perfused pressure catheter. A pH probe was placed in the duodenal bulb. Baseline mo...

journal_title：Digestive diseases and sciences

authors： McDonnell WM,Owyang C

更新日期：1995-12-01 00:00:00

abstract：:The intrarectal administration of trinitrobenzene sulfonic acid in rats induces ulcerative colitis, which results in histological alterations of colonic mucosa, severe modification of the cellular antioxidant defense system, and enhanced production of inflammatory eicosanoids. This study evaluated the influence of dif...

journal_title：Digestive diseases and sciences

authors： Nieto N,Fernandez MI,Torres MI,Ríos A,Suarez MD,Gil A

更新日期：1998-12-01 00:00:00

abstract：:Minimal hepatic encephalopathy (MHE) is characterized by disturbance of mental state and neuromuscular function. To assess the clinical efficacy of acetyl-L: -carnitine (ALC) in the treatment of MHE, we performed a randomized, double-blind, placebo-controlled study administering ALC in cirrhotic patients with this dis...

journal_title：Digestive diseases and sciences

authors： Malaguarnera M,Gargante MP,Cristaldi E,Vacante M,Risino C,Cammalleri L,Pennisi G,Rampello L

更新日期：2008-11-01 00:00:00

abstract：:The growth of the human gastrinoma model (PT) in athymic nude mice is stimulated by bombesin (BBS), an amphibian peptide homologous to both human gastrin-releasing peptide (GRP) and neuromedin B (NMB). The mechanism is not known, and a potent and specific GRP-R antagonist BIM26226, which has low affinity for NMB-R, wa...

journal_title：Digestive diseases and sciences

authors： Chu KU,Ishizuka J,Battey JF,Uchida T,Beauchamp RD,Townsend CM Jr,Thompson JC

更新日期：1996-11-01 00:00:00

abstract：:We examined the influences of aging on gastric damage and gastric mucosal blood flow (GMBF) responses induced by acid back-diffusion, following the barrier disruption, and investigated the relation of capsaicin-sensitive sensory nerves to these changes. Male Fischer rats 3, 13, and 24 months old were used. Under ureth...

journal_title：Digestive diseases and sciences

authors： Miyake H,Inaba N,Kato S,Takeuchi K

更新日期：1996-02-01 00:00:00

abstract：:The purpose of this study was to use simultaneous anal manometry and high-frequency endoluminal ultrasonography (EUS) to determine the relationship between resting anal pressure and cross-sectional area of the internal and external anal sphincters. Eleven normal subjects underwent simultaneous anal EUS and manometry u...

journal_title：Digestive diseases and sciences

authors： Wong RF,Bonapace ES Jr,Chung CY,Liu JB,Parkman HP,Miller LS

更新日期：1998-11-01 00:00:00

abstract：:Cytomegalovirus (CMV) inclusions were found at colonic perforation sites in three patients with clinical settings suggesting a compromised immunologic status. This could be interpreted as: (1) CMV was an etiologic agent in these perforations; or (2) CMV was an opportunistic superinfection in areas of preexisting infla...

journal_title：Digestive diseases and sciences

authors： Goodman ZD,Boitnott JK,Yardley JH

更新日期：1979-05-01 00:00:00

abstract：:The purpose of the present study was to investigate the Helicobacter pylori eradication potency of combined amoxicillin-omeprazole treatment in patients with duodenal ulcer disease and to compare the efficacy of two omeprazole and amoxicillin doses concerning H. pylori eradication, ulcer healing, pain relief, and safe...

journal_title：Digestive diseases and sciences

authors： Labenz J,Rühl GH,Bertrams J,Börsch G

更新日期：1994-07-01 00:00:00

abstract：:Sera from Japanese patients with chronic liver disease were tested for hepatitis B virus (HBV) markers and antibodies to hepatitis C virus (anti-HCV), and the results were correlated to the presence of hepatocellular carcinoma. In chronic non-A, non-B liver disease, anti-HCV prevalence was high both in patients with h...

journal_title：Digestive diseases and sciences

authors： Yuki N,Hayashi N,Kasahara A,Hagiwara H,Katayama K,Fusamoto H,Kamada T

更新日期：1992-01-01 00:00:00

abstract：:The early rebound in serum HCV RNA during HCV dynamic studies with high-dose interferon may be due to de novo infection with interferon escape quasispecies. We simultaneously measured serum alanine aminotransferase (ALT) and HCV RNA at rapid intervals in chronic HCV liver disease patients during interferon therapy alo...

journal_title：Digestive diseases and sciences

authors： Lake-Bakaar G,Ruffini L,Kuzmic P

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Liver stiffness measurement (LSM) by transient elastography is a popular noninvasive test of fibrosis. Traditional LSM cutoffs dichotomize patients and do not clearly indicate the confidence of diagnosis. AIM:We derived and validated probability functions of fibrosis and cirrhosis based on LSM and determine...

journal_title：Digestive diseases and sciences

authors： Wong VW,Lampertico P,de Lédinghen V,Chang PE,Kim SU,Chen Y,Chan HL,Mangia G,Foucher J,Chow WC,Ahn SH,Hou J

更新日期：2015-05-01 00:00:00

abstract：:Our aim was to define the utility of breath ammonia measurement in assessing Helicobacter pylori infection. Volunteers breathed into a device containing three fiberoptic NH3 sensors at baseline and after ingesting 300 mg of urea. Breath ammonia levels were compared to the [14C]urea breath test. Thirteen subjects were ...

journal_title：Digestive diseases and sciences

authors： Kearney DJ,Hubbard T,Putnam D

更新日期：2002-11-01 00:00:00