Validation of cardiac output measurement by ultrasound dilution technique with pulmonary artery thermodilution in a pediatric animal model.


:Novel COstatus system (Transonic Systems, Inc., NY), based on ultrasound dilution (UD), works off in situ arterial and central venous catheters in pediatric patients to measure cardiac output (CO). The purpose of the present study was to validate CO measurement by UD (COUD) with pulmonary artery (PA) thermodilution (COTD) in a prospective animal study. Ten anesthetized pigs (16-45 kg) were instrumented with pediatric PA, central venous, and peripheral artery catheters. For COUD measurements, normothermic saline (0.5-1.0 ml/kg body weight, up to a maximum of 30 ml) was injected into the venous limb of an arteriovenous loop that was connected between in situ catheters. For COTD measurements, 5-10 ml cold saline was injected into the PA catheter. Sixty-four averaged sets were obtained for comparison. COTD mean was 2.98 ± 1.21 l/min (range 1.33-6.29), and COUD mean was 2.68 ± 1.16 l/min (range 1.33-5.85). This study yielded a correlation r = 0.96, COUD = 0.91*(COTD) - 0.04 l/min; bias was 0.3 l/min with limits of agreement as -0.39 to 0.99 l/min; and the percentage error was 23.73% between the methods. CO measurements by UD agreed well with thermodilution measurements in the pediatric swine model.


Pediatr Cardiol


Pediatric cardiology


Darling E,Thuramalla N,Searles B




Has Abstract


2011-06-01 00:00:00












  • Subcostal two-dimensional echocardiographic recognition of a criss-cross heart with discordant ventriculo-arterial connection.

    abstract::Two-dimensional echocardiography was performed on a patient with criss-cross atrioventricular (AV) relationship and ventriculo-arterial discordance. A systematic approach from the subcostal area revealed the complex cardiac pathology including the criss-cross AV relationship of right and left heart, indicating that th...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: van Mill G,Moulaert A,Harinck E,Wenink A,Oppenheimer-Dekker A

    更新日期:1982-01-01 00:00:00

  • Use of adenosine in multiple doses for supraventricular tachycardia in an infant.

    abstract::The treatment of recurrent supraventricular tachycardia in a 3-week-old infant is described. Multiple doses of adenosine were used successfully to convert the dysrhythmia, without adverse effects or apparent tachyphylaxis. ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Fitzsimmons CL,Withington DE

    更新日期:1997-11-01 00:00:00

  • Trends in Infant Mortality After TAPVR Repair over 18 Years in Texas and Impact of Hospital Surgical Volume.

    abstract::For some congenital heart lesions, higher institutional surgical volume has been associated with better survival than in lower volume centers. The relationship between institutional surgical volume and mortality in infants after total anomalous pulmonary vein return (TAPVR) repair has not been well explored. The Texas...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Lahiri S,Wang Y,Caldarone CA,Morris SA

    更新日期:2020-01-01 00:00:00

  • Loss of Consciousness in the Young Child.

    abstract::In the very young child (less than eight years of age), transient loss of consciousness represents a diagnostic and management dilemma for clinicians. While most commonly benign, syncope may be due to cardiac dysfunction which can be life-threatening. It can be secondary to an underlying ion channelopathy, cardiac inf...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,评审


    authors: Villafane J,Miller JR,Glickstein J,Johnson JN,Wagner J,Snyder CS,Filina T,Pomeroy SL,Sexson-Tejtel SK,Haxel C,Gottlieb J,Eghtesady P,Chowdhury D

    更新日期:2021-01-02 00:00:00

  • Parent stress levels during children's hospital recovery after congenital heart surgery.

    abstract::The hospitalization of a child for cardiac surgery is known to be a stressful experience for parents. However, little is known about the time course or the relationships between parental stress and the child's actual or perceived recovery. This research aimed to investigate pre- and postoperative parental stress and t...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Franck LS,McQuillan A,Wray J,Grocott MP,Goldman A

    更新日期:2010-10-01 00:00:00

  • Effective radiation dose in computed tomographic angiography of the chest and diagnostic cardiac catheterization in pediatric patients.

    abstract::Computed tomographic angiography (CTA) and cardiac catheterization are useful adjuncts to echocardiography for delineating cardiovascular anatomy in pediatric patients. These studies require ionizing radiation, and it is paramount to understand the amount of radiation pediatric patients receive when these tests are pe...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Watson TG,Mah E,Joseph Schoepf U,King L,Huda W,Hlavacek AM

    更新日期:2013-03-01 00:00:00

  • The impact of fetal echocardiography.

    abstract::Fetal echocardiography has impacted the fetus with congenital heart disease in many important ways. Advances in fetal echocardiography have allowed for more accurate and earlier detection of cardiac abnormalities. In turn, the prenatal diagnosis of cardiac abnormalities has improved the care and outcome of selected fe...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,评审


    authors: Kovalchin JP,Silverman NH

    更新日期:2004-05-01 00:00:00

  • First case of intracardiac foregut cyst occurring in the left-ventricular outflow tract.

    abstract::An 11 day-old female infant underwent resection of a mass in the subaortic region secondary to critical aortic stenosis. At 3 months of age, recurrent severe left-ventricular outflow obstruction (LVOT) in the setting of heart failure prompted redo surgery, and the resected mass revealed an intracardiac foregut cyst, w...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Huang JH,Rudzinski ER,Minette MS,Langley SM

    更新日期:2013-01-01 00:00:00

  • Balloon angioplasty for native aortic coarctation in different anatomic variants.

    abstract::Balloon angioplasty for native coarctation of the aorta in infants and children is gaining acceptance as an alternative to surgery in discrete membranous obstruction. The aim of this study was to assess the immediate and intermediate-term effectiveness and safety of balloon angioplasty in infants and children with dis...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Massoud Iel S,Farghly HE,Abdul-Monem A,Botros N,Kassem A,Magraby AE,Dawood A,Abdul-Hakam M

    更新日期:2008-05-01 00:00:00

  • Crossed pulmonary arteries: a report on 20 cases with an emphasis on the clinical features and the genetic and cardiac abnormalities.

    abstract::Crossed pulmonary arteries (CPAs) are a rare abnormality in which the ostium of the left pulmonary artery originates superior to the right pulmonary artery and to its right. Recognition of this rare pathology is important because it generally is accompanied by other congenital heart defects, extracardiac anomalies, an...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Babaoğlu K,Altun G,Binnetoğlu K,Dönmez M,Kayabey Ö,Anık Y

    更新日期:2013-01-01 00:00:00

  • Hypocalcemic rickets and dilated cardiomyopathy: case reports and review of literature.

    abstract::Internationally, there have been isolated case reports published of children presenting with dilated cardiomyopathy (DCM) in the setting of undiagnosed rickets. Although there has been an increased prevalence of rickets in the United States, there has been only one documented case of associated DCM. At our institution...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Brown J,Nunez S,Russell M,Spurney C

    更新日期:2009-08-01 00:00:00

  • Feasibility and Efficacy of Defatted Human Milk in the Treatment for Chylothorax After Cardiac Surgery in Infants.

    abstract::Chylothorax is a well-described complication after cardiothoracic surgery in children. Medical nutritional therapy for chylothorax includes medium-chain triglyceride (MCT) formulas and reduction in enteral long-chain triglyceride intake to reduce chyle production. Human milk is usually eliminated from the diet of infa...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Fogg KL,DellaValle DM,Buckley JR,Graham EM,Zyblewski SC

    更新日期:2016-08-01 00:00:00

  • Growth of an atrial septal defect: missing the window for transcatheter closure.

    abstract::We describe a patient diagnosed with a small atrial septal defect (3-4 mm) that had grown to 24 mm in diameter over a six-year period. Timing of transcatheter intervention may be affected by growth of the atrial septal defect and this reports the first case of an atrial septal defect outgrowing the possibility of tran...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Tortoriello TA,McMahon C,Kovalchin JP,Bricker JT,Grifka RG

    更新日期:2002-09-01 00:00:00

  • Test characteristics of a level I or II fetal ultrasound in detecting structural heart disease.

    abstract::At the University of California Davis Medical Center, a screening fetal ultrasound examination (level I or II) incorporates a comprehensive segmental evaluation of the fetal heart. This study evaluated the reliability of the fetal ultrasound exam in the detection of abnormal heart anatomy. Our retrospective study revi...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Skeels M,Taylor D,Park J,Parrish M,Choy M

    更新日期:2002-11-01 00:00:00

  • Congenitally corrected transposition of the great arteries in a patient with cor triatriatum: a rare combination.

    abstract::Congenitally corrected transposition of the great arteries is a rare anomaly that is thought to arise from a defect in looping of the primitive cardiac tube. Cor triatriatum is another rare congenital cardiac anomaly due to faulty incorporation of the common pulmonary vein into the left atrium. We present a rare case ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Jayranganath M,Subramanian A,Manjunath CN

    更新日期:2011-04-01 00:00:00

  • Radionuclide evaluation of right ventricular wall motion after surgery in tetralogy of Fallot.

    abstract::Regional wall motion patterns in tetralogy of Fallot and its postoperative modifications by electrical and hemodynamic factors were assessed by Fourier analysis of gated radionuclide angiograms in 24 studies performed in children after surgical correction of tetralogy of Fallot. The range of right ventricular (RV) pha...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Ratib O,Friedli B,Righetti A,Oberhaensli I

    更新日期:1989-01-01 00:00:00

  • Complex congenital cardiovascular anomalies evaluated by continuous-rotation computed tomography in children.

    abstract::The slip ring and nutate/rotate configuration of the new, fourth-generation, computed tomography (CT) (TCT-900S, Toshiba Medical Company) makes it possible to scan consecutively 25 slices every 75 s. This scanner also rapidly provides hemodynamic and multiplanar reconstruction images. Studies were performed on 13 chil...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Yamada T,Harada J,Tada S

    更新日期:1989-04-01 00:00:00

  • Complete Repair of Tetralogy of Fallot in the Neonatal Versus Non-neonatal Period: A Meta-analysis.

    abstract::It is unclear if neonatal tetralogy of Fallot repair offers better outcomes compared to repair later in infancy. We therefore conducted a meta-analysis comparing outcomes of neonatal and non-neonatal repair. Manuscripts were identified and reviewed for quality and bias with favorably scored manuscripts being included ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,meta分析,评审


    authors: Loomba RS,Buelow MW,Woods RK

    更新日期:2017-06-01 00:00:00

  • Longer Ischemic Time is Associated with Increased Ventricular Stiffness as Measured by Pressure-Volume Loop Analysis in Pediatric Heart Transplant Recipients.

    abstract:BACKGROUND:The purpose of this study was to investigate the associations between clinical factors and cardiac function as measured by pressure-volume loops (PVLs) in a pediatric heart transplant cohort. METHODS:Patients (age < 20 years) who underwent heart transplantation presenting for a clinically indicated catheter...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Schroeder LW,Chowdhury SM,Burnette AL,Kavarana MN,Hamilton Baker G,Savage AJ,Atz AM,Butts RJ

    更新日期:2018-02-01 00:00:00

  • Surgical Timing and Outcomes of Unilateral Versus Bilateral Superior Cavopulmonary Anastomosis: An Analysis of Pediatric Heart Network Public Databases.

    abstract::Requiring bilateral superior cavopulmonary anastomosis (bSCPA) instead of unilateral superior cavopulmonary anastomosis (uSCPA) could influence surgical timing and outcomes. We compared surgical timing and outcomes for patients who underwent uSCPA to those who underwent bSCPA through use of the Pediatric Heart Network...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Shuler JM,Statile C,Heydarian H,Lehenbauer DG,Hill GD

    更新日期:2021-01-08 00:00:00

  • Chronic Low Dose Prostaglandin and Neonatal Heart Block.

    abstract::Long-term prostaglandin use is commonly associated with side effects such as cortical proliferation of the bones, hypertrophic pyloric stenosis, and soft tissue swelling of the extremities. We report a neonate with critical coarctation of the aorta, who developed second and third degree atrioventricular blocks associa...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Aly SA,Awad SM,Abdulla RI,Kazmouz S,Nguyen HH

    更新日期:2017-10-01 00:00:00

  • Echocardiographically guided balloon atrial septostomy during extracorporeal membrane oxygenation (ECMO).

    abstract::Use of extracorporeal membrane oxygenation (ECMO) in infants with congenital heart disease is becoming more frequent. We present the first reported use of balloon atrial septostomy during ECMO support and describe possible complications of such procedures unique to ECMO therapy. ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: O'Connor TA,Downing GJ,Ewing LL,Gowdamarajan R

    更新日期:1993-07-01 00:00:00

  • Changes in Ventricular Geometry Predict Severity of Right Ventricular Hypertension.

    abstract::Changes in ventricular geometry are often seen in patients with right ventricular hypertension secondary to pulmonary hypertension (PH). Progressive systolic bowing of the inter-ventricular septum occurs with increasing right ventricular pressure (RVp) and can be quantified with the left ventricular end-systolic eccen...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Averin K,Michelfelder E,Sticka J,Cash M,Hirsch R

    更新日期:2016-03-01 00:00:00

  • The Influence of Fluid Overload on the Length of Mechanical Ventilation in Pediatric Congenital Heart Surgery.

    abstract::Fluid overload and prolonged mechanical ventilation lead to worse outcomes in critically ill children. However, the association between these variables in children following congenital heart surgery is unknown. The objectives of this study were to describe the association between fluid overload and duration of mechani...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Sampaio TZ,O'Hearn K,Reddy D,Menon K

    更新日期:2015-12-01 00:00:00

  • Interruption of aortic arch and hypoplastic left heart syndrome.

    abstract::Interruption of the aortic arch and hypoplastic left heart syndrome in the same patient is exceptional. In the combined collections of the Registry of Cardiovascular Disease (St. Paul, Minnesota, U.S.A.) and the Registry of Congenital Heart Defects of the Rijksuniversiteit Gent (Gent, Belgium) three specimens were fou...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,评审


    authors: Devloo-Blancquaert A,Titus JL,Edwards JE,Vallaeys JH,De Gezelle HR,Coppens M

    更新日期:1995-11-01 00:00:00

  • A Novel Somatic Variant in HEY2 Unveils an Alternative Splicing Isoform Linked to Ventricular Septal Defect.

    abstract::Congenital heart defects (CHDs) are the leading cause of death in infants under 1 year of age. Aberrations in the expression and function of cardiac transcription factors (TFs) are a major contributor to CHDs. Despite the numerous studies undertaken to functionally characterize these TFs, their exact role in different...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Fardoun M,Dehaini H,Kamar A,Bitar F,Majdalani M,El-Rassi I,Nemer G,Arabi M

    更新日期:2019-06-01 00:00:00

  • Ventricular inversion and tricuspid atresia (VITA complex): long survival without surgical treatment.

    abstract::Five patients with ventricular inversion, corrected transposition of the great arteries, and atresia of the left-sided atrioventricular (tricuspid) valve have been observed. Three patients died in infancy, two had large interatrial communications, one with an early stage of arterial-type hypertensive pulmonary vascula...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Tazelaar HD,Moore GW,Hutchins GM

    更新日期:1986-01-01 00:00:00

  • Morbidities in patients with hypoplastic left heart syndrome.

    abstract::We sought to document morbidities and growth for patients with hypoplastic left heart syndrome (HLHS) to inform the initial surgical decision and understand healthcare needs. Data were obtained on 137 patients with HLHS, born between 1989 and 1994, who survived staged surgery ( n = 62) or transplantation ( n = 75) and...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,多中心研究


    authors: Jenkins PC,Flanagan MF,Jenkins KJ,Sargent JD,Canter CE,Chinnock RE,Vincent RN,O'Connor GT

    更新日期:2004-01-01 00:00:00

  • Malalignment of the septum primum with abnormally positioned left atrial appendage: unusual combination in a Shone's heart.

    abstract::This case discusses a Shone's variant with small left ventricle and mitral valve, bicuspid aortic valve, coarctation of the aorta, an unusual arrangement of atrial appendages, and partially anomalous pulmonary venous drainage due to a deviated atrial septum. The left atrial appendage could be directly entered from the...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Kurio GH,Gulati R,Bichell DP,Perry JC

    更新日期:2006-09-01 00:00:00

  • Angiotensin-converting enzyme inhibitor nephrotoxicity in neonates with cardiac disease.

    abstract::Angiotensin-converting enzyme inhibitors (ACEi) are commonly used for pediatric cardiology patients. However, studies examining their safety for neonates with cardiac disease are scarce. The current study aimed to test the hypothesis that ACEi-mediated nephrotoxicity occurs in neonates and may be underappreciated in t...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Lindle KA,Dinh K,Moffett BS,Kyle WB,Montgomery NM,Denfield SD,Knudson JD

    更新日期:2014-03-01 00:00:00