Abstract：
:This prospective observational study conducted in a neonatal intensive care unit aimed to evaluate echocardiographic changes provoked by anemia and transfusion of packed red blood cells (pRBCs) in premature infants. In this study, 32 anemic premature infants had serial echocardiographic assessment of left ventricular (LV) systolic performance, LV preload, and afterload immediately before, within 48 h, and up to 120 h after the transfusion of pRBCs. Pretransfusional evaluations also were compared with similar assessments of 71 nonanemic inpatient premature infants analogous for sex, gestational age at birth, and postnatal age. Left ventricular systolic performance was estimated from fractional shortening, LV output, and LV myocardial performance index (LVMPI). The LV preload was estimated from the LV end-diastolic dimension and the ratio of left atrium-to-aortic root dimension (LA/Ao ratio). The LV afterload was estimated from end-systolic wall stress. The LVMPI was found to decrease with increasing corrected gestational age in both the nonanemic (R = 0.173; p = 0.03) and anemic (R = 0.460; p = 0.007) infants. The LVMPI was the only index that changed after transfusion of pRBCs, decreasing in the younger anemic infants (p = 0.011) and increasing in the older anemic infants (p = 0.012). Finally, a significant inverse relationship between pre- and posttransfusional LVMPI values (R = 0.730; p < 0.001) was noted. The LVMPI may allow for identification of preterm infants more likely to be helped by transfusion of pRBCs.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Radicioni M,Troiani S,Mezzetti Ddoi
10.1007/s00246-012-0154-6subject
Has Abstractpub_date
2012-04-01 00:00:00pages
554-61issue
4eissn
0172-0643issn
1432-1971journal_volume
33pub_type
杂志文章abstract：:We report hemodynamic findings in two patients with pulmonary atresia and intact ventricular septum (PAIVS) after "one-and-a-half ventricle repair" and placement of a bidirectional Glenn shunt using four-dimensional (4D) flow magnetic resonance imaging. Quantification of flow and analysis of flow patterns revealed the...
journal_title：Pediatric cardiology
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pub_type： 杂志文章,多中心研究
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-1274-z
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journal_title：Pediatric cardiology
pub_type： 杂志文章
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pub_type： 杂志文章,评审
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journal_title：Pediatric cardiology
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1135-3
更新日期：2015-08-01 00:00:00
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journal_title：Pediatric cardiology
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doi：10.1007/s00246-013-0724-2
更新日期：2013-01-01 00:00:00
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journal_title：Pediatric cardiology
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doi：10.1007/BF02524804
更新日期：1996-07-01 00:00:00
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