Abstract：
:That apoptosis is mediated by specific pathways has long been established. However, more recent data have begun to suggest that necrosis may in fact be "programmed" and not a default "accidental" pathway as previously thought. The mitochondrial permeability transition pore, a known contributor to the development of many cardiac diseases, is emerging as one among several mediators of this necrotic program. Consequently, this report briefly reviews the roles of necrosis versus apoptosis in the pathogenesis of cardiac disease and discusses the role that the mitochondrial pore plays in cardiac necrotic cell death.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Baines CPdoi
10.1007/s00246-010-9880-9subject
Has Abstractpub_date
2011-03-01 00:00:00pages
258-62issue
3eissn
0172-0643issn
1432-1971journal_volume
32pub_type
杂志文章abstract：:Inferior sinus venosus defects (SVDs) are rare imperfections located in the inferior portion of the atrial septum, leading to an overriding inferior vena cava (IVC) and an interatrial connection. These defects have increased risk of anomalous pulmonary venous return (PAPVR) and often are confused with secundum atrial ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0449-7
更新日期：2013-02-01 00:00:00
abstract：:Pulmonary artery banding (PAB) is used as a surgical palliation to reduce excessive pulmonary blood flow caused by congenital heart defects. Due to the lack of microscopic studies dealing with the tissue remodeling caused by contemporary PAB materials, this study aimed to assess histologic changes associated with PAB ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0699-z
更新日期：2013-10-01 00:00:00
abstract：:A rare case of isolated innominate artery arising from a left persistent arterial duct with a right aortic arch is presented. Of interest in this case is the retrograde flow in the left carotid system, the history of developmental delay, and the magnetic resonance image (MRI) brain findings suggestive of asymmetric vo...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9739-0
更新日期：2010-10-01 00:00:00
abstract：:To examine factors associated with low high-density lipoprotein cholesterol (HDL-C) levels among middle school children. HDL-C levels were the primary outcome of interest. A total of 1,104 middle-school children (mean age 11.6 years, 51.2% female) were included in this analysis, of whom 177 (16%) had an HDL-C level ≤4...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-013-0814-1
更新日期：2014-03-01 00:00:00
abstract：:Over the past decade, revolutionary advances in ultrasound imaging technology have allowed the study of the evolution of congenital heart disease during fetal life. The frustration arising from watching the prenatal progression of severe semilunar valve obstructions and therapy-refractory fetal arrhythmias has prompte...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-001-0197-6
更新日期：2002-05-01 00:00:00
abstract：:The objective of this study is to identify predictors of prolonged hospital length of stay (LOS) for single ventricle patients following stage 2 palliation (S2P), excluding patients who underwent a hybrid procedure. We explore the impact of demographic features, stage 1 palliation (S1P), interstage I (IS1) management,...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1208-3
更新日期：2015-12-01 00:00:00
abstract：:While exercise stress testing (EST) is an important tool, little is known about its use for determining ischemia in patients with hypoplastic left heart syndrome (HLHS) and Fontan palliation. We sought to determine the frequency of ST segment changes during EST in HLHS patients after Fontan and examine results of furt...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1312-4
更新日期：2016-03-01 00:00:00
abstract：:With improvements in technology and surgical technique, pediatric cardiologists are challenging surgeons to close symptomatic ventricular septal defects (VSDs) in ever smaller patients. Although delaying surgery may facilitate operative repair, early intervention decreases the period of time these patients require the...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9016-z
更新日期：2008-01-01 00:00:00
abstract：:Kawasaki disease (KD) is a self-limiting systemic vasculitis of unknown etiology. KD is often complicated by coronary artery aneurysms (CAAs), which develop in about 20-25% of untreated children and 3-5% of children treated with intravenous immunoglobulin therapy. To identify the risk loci for CAA susceptibility in pa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1992-7
更新日期：2019-03-01 00:00:00
abstract：:A 4-year-old girl had the insidious onset of congestive heart failure without apparent cause. Evaluation by echocardiography, thallous chloride TI 201 scintigraphy, and angiography suggested the presence of either a neoplasm or restrictive cardiomyopathy with a localized mass effect on the left ventricle. Pathological...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02312963
更新日期：1982-01-01 00:00:00
abstract：:Intravenous immunoglobulin (IVIG) administered in the acute stage of Kawasaki disease (KD) is the standard therapy. Few reports describe nonresponders to initial treatment with IVIG in KD, which remains the most consistent risk factor for coronary artery lesions (CALs). This study aimed to investigate whether the seru...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0724-2
更新日期：2013-01-01 00:00:00
abstract：:Various surgical techniques have been proposed for the repair of supravalvular pulmonary stenosis (SVPS) in pediatric populations. Whereas growth potential should be promised, excessive expansion under the presence of undiminished high pulmonary arterial pressure should be avoided. The authors applied all-autologous t...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0698-0
更新日期：2013-10-01 00:00:00
abstract：:A reduced exercise capacity is a common finding in adult congenital heart disease and is associated with cardiovascular morbidity and mortality. However, data on exercise capacity in patients after repair of coarctation of the aorta (CoA) are scarce. Furthermore, a high rate of exercise-induced hypertension has been d...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02173-5
更新日期：2019-10-01 00:00:00
abstract：:This study examined the age-related criteria of signal-averaged electrocardiographic (SA-ECG) parameters in children. SA-ECGs were obtained in 82 healthy volunteers in six groups depending on age (group 1: 1 day to < 1 month; group 2: 1 month to < 1 year; group 3: 1 to < 6 years; group 4: 6 to < 12 years; group 5: 12 ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00796320
更新日期：1994-05-01 00:00:00
abstract：:Controversy exists as to whether a hemodynamically significant left-to-right shunt due to a patent ductus arteriosus (PDA) affects ventricular contractility. Load-dependent indices such as ejection fraction and shortening fraction have traditionally been used to assess contractility, but the relationship between the r...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0452-0
更新日期：2004-03-01 00:00:00
abstract：:This study aimed to determine the dimensions of the thoracic aorta and the predictors of aortic dimensions in girls and young women with Turner syndrome (TS). A cross-sectional study was performed at a secondary care center. The study compared 41 TS patients with 50 healthy age-matched control subjects. The mean age o...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9626-8
更新日期：2010-05-01 00:00:00
abstract：:The outcome of children born with cyanotic congenital heart disease has markedly improved over the years. Follow up is recommended for most post-operated cases as complications may occur over long term. One of the complications is the development of ventricular dysfunction, often seen after a successful Fontan surgery...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0531-1
更新日期：2013-04-01 00:00:00
abstract：:Noonan syndrome is an autosomal dominant disease that manifests a wide variety of clinical characteristics. The syndrome is also associated with some cardiac defects. Half of all Noonan syndrome cases are caused by mutations in the PTPN11 gene, but only limited data are available regarding aortic involvement in these ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9537-8
更新日期：2010-01-01 00:00:00
abstract：:Computed tomographic angiography (CTA) and cardiac catheterization are useful adjuncts to echocardiography for delineating cardiovascular anatomy in pediatric patients. These studies require ionizing radiation, and it is paramount to understand the amount of radiation pediatric patients receive when these tests are pe...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0486-2
更新日期：2013-03-01 00:00:00
abstract：:Color-coded two-dimensional (2D) echocardiography confirmed the presence of severe congenital mitral regurgitation in an 8-month-old infant. Intraoperative inspection revealed an isolated perforation in the anterior leaflet. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02239570
更新日期：1990-04-01 00:00:00
abstract：:In our institute, 1100 patients with a history of Kawasaki disease have been catheterized for selective coronary arteriography. Their age at examination ranged from four months to 13 years. Coronary artery lesions (CAL) were found in 262 patients. As far as the type of the CAL was concerned, occlusion was noted in 20 ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02315475
更新日期：1986-01-01 00:00:00
abstract：:Myocardial contractility and relaxation are highly dependent on calcium homeostasis. Immature myocardium, as in pediatric patients, is thought to be more dependent on extracellular calcium for optimal function. For this reason, intravenous calcium chloride infusions may improve myocardial function in the pediatric pat...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1322-2
更新日期：2016-03-01 00:00:00
abstract：:Respiratory viral infections in infants undergoing congenital heart surgery lead to prolonged intubation time, hospital (HLOS) and cardiac intensive care unit length of stay (CICU LOS). The objective of this study was to evaluate the prevalence of respiratory viruses using molecular testing in otherwise healthy infant...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1994-5
更新日期：2019-02-01 00:00:00
abstract：:Calculating pulmonary vascular resistance is important in many fields of medicine. Although the influence of hematocrit on calculated resistance has been known for many years, it is rare to find the appropriate corrections in published articles. This review discusses the relationship between viscosity and resistance a...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-011-9954-3
更新日期：2011-06-01 00:00:00
abstract：:For neonates with right atrial isomerism (RAI), functional single ventricle (f-SV), and obstructive total anomalous pulmonary venous connection (TAPVC), primary TAPVC repair (TAPVCR) has a poor outcome. At our hospital, the survival rate at 1 year of such neonates undergoing primary TAPVCR between 1999 and 2010 (TAPVC...
journal_title：Pediatric cardiology
pub_type： 杂志文章,收录出版
doi：10.1007/s00246-018-1902-z
更新日期：2018-10-01 00:00:00
abstract：:Avoidance of red blood cell (RBC) transfusions in patients awaiting heart transplantation (HTx) has been suggested to minimize the risk of allosensitization. Although recent studies have suggested that an immature immune system in younger HTx recipients may reduce risks associated with RBC transfusion, the role of age...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1814-y
更新日期：2018-04-01 00:00:00
abstract：:A 5-year-old child with a Fontan circulation presented with acquired left pulmonary vein occlusion related to a previous surgical repair. We managed this lesion using a hybrid technique to perforate, dilate and stent the obstructed vessel. This approach should be considered when percutaneous access to the pulmonary ve...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1376-9
更新日期：2016-06-01 00:00:00
abstract：:Novel COstatus system (Transonic Systems, Inc., NY), based on ultrasound dilution (UD), works off in situ arterial and central venous catheters in pediatric patients to measure cardiac output (CO). The purpose of the present study was to validate CO measurement by UD (COUD) with pulmonary artery (PA) thermodilution (C...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-9915-x
更新日期：2011-06-01 00:00:00
abstract：:Protein-losing enteropathy (PLE) and plastic bronchitis (PB) are major causes of long-term mortality after Fontan operation. The objective of this study was to determine early clinical risk factors before the onset of PLE and PB. In a cohort study, 106 Fontan patients between 2005 and 2013 were examined. A median of 5...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-017-1632-7
更新日期：2017-08-01 00:00:00
abstract：:The outcome in a series of 23 cases of tetralogy of Fallot diagnosed prenatally was compared to published figures for this condition when (a) identified postnatally or (b) treated surgically. There was a marked difference in the survival between these groups, with the highest mortality (75%) occurring when the diagnos...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00788220
更新日期：1992-01-01 00:00:00
