Abstract:
:Respiratory viral infections in infants undergoing congenital heart surgery lead to prolonged intubation time, hospital (HLOS) and cardiac intensive care unit length of stay (CICU LOS). The objective of this study was to evaluate the prevalence of respiratory viruses using molecular testing in otherwise healthy infants presenting for low complexity heart surgery, and to evaluate the impact of a positive viral screen and study questionnaire on post-surgical HLOS, CICU LOS, intubation time, respiratory complications, and oxygen therapy at home discharge. Sixty-nine infants (1 month to 1 year) undergoing cardiac surgery from November to May of the years 2012 to 2014 were prospectively enrolled, surveyed and tested. We compared the outcomes of positive molecular testing and positive study questionnaire to test negative subjects. We also evaluated the predictive value of study questionnaire in identification of viruses by molecular testing. Of the 69 enrolled infants, 58 had complete information available for analysis. 17 (30%) infants tested positive by molecular testing for respiratory pathogens. 38 (65%) had a "positive" questionnaire. Among the 20 viruses detected, Human Rhinovirus was the most common 12 (60%). Seven (12%) of the 58 patients developed respiratory symptoms following surgery prompting molecular testing. Four of these tested positive for a respiratory virus post-surgically. Neither positive molecular testing nor a positive questionnaire prior to surgery was associated with greater post-operative HLOS, CICU LOS, intubation time, respiratory complications, or use of oxygen at discharge compared to negative testing. The questionnaire poorly predicted positive molecular testing. Routine screening for respiratory viruses in asymptomatic infants may not be an effective strategy to predict infants at risk of post-operative complications.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Delgado-Corcoran C,Blaschke AJ,Ou Z,Presson AP,Burch PT,Pribble CG,Menon SCdoi
10.1007/s00246-018-1994-5subject
Has Abstractpub_date
2019-02-01 00:00:00pages
339-348issue
2eissn
0172-0643issn
1432-1971pii
10.1007/s00246-018-1994-5journal_volume
40pub_type
杂志文章abstract::Ventricular dysfunction in patients after Fontan-like operations (FLOs) is a serious complication that might contribute to poor long-term results. Ischemic heart disease will have debilitating consequences on a Fontan heart. Ten patients (15.8 +/- 5.01 years) after FLO had transesophageal echocardiography and cardiac ...
journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s002469900195
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journal_title:Pediatric cardiology
pub_type: 杂志文章
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更新日期:2008-03-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF00817618
更新日期:1994-03-01 00:00:00
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-011-9920-0
更新日期:2011-03-01 00:00:00
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journal_title:Pediatric cardiology
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doi:10.1007/s00246-013-0842-x
更新日期:2014-04-01 00:00:00
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journal_title:Pediatric cardiology
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doi:10.1007/s00246-018-1927-3
更新日期:2018-12-01 00:00:00
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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更新日期:2001-09-01 00:00:00
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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更新日期:1995-07-01 00:00:00
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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更新日期:1991-07-01 00:00:00
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abstract::Persistent pulmonary hypertension of the newborn (PPHN) complicated with transposition of the great arteries (TGA) and an intact ventricular septum (IVS) often is therapy resistant and associated with an extremely poor prognosis. For this condition, opening of the ductus arteriosus (DA) by prostaglandin-E1 in conjunct...
journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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更新日期:2006-01-01 00:00:00
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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