The growth hormone, prolactin and TSH response to TRH and L-dopa in patients with hyperprolactinaemia and a normal-sized sella turcica may denote a pituitary adenoma.

abstract：:A total of 4401 subjects admitted to the Medical Division of St Camillo Hospital in Comacchio (Ferrara, Italy) over a period of 7 years were prospectively evaluated in order to determine whether the heterozygous beta-thalassaemic (HBT) could be considered as a protective factor against the occurrence of acute myocardi...

journal_title：Journal of internal medicine

authors： Gallerani M,Scapoli C,Cicognani I,Ricci A,Martinelli L,Cappato R,Manfredini R,Dall'Ara G,Faggioli M,Pareschi PL

更新日期：1991-08-01 00:00:00

abstract：:Type 2 diabetes (T2DM) is a rapidly growing public health problem. It is associated with an increased risk of fracture, particularly of the hip, despite normal or high bone mineral density. Longer duration of disease and poor glycaemic control are both associated with higher fracture risk. The factors underlying incre...

journal_title：Journal of internal medicine

authors： Compston J

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To evaluate primary hyperparathyroidism (HPT) as a risk factor for hip fractures. DESIGN:A population-based, record-linked, prospective study with a mean observation time of 17 years (women) and 16.5 years (men). SETTING:A cohort obtained from a register of hospital admissions in the Uppsala Health Care Reg...

journal_title：Journal of internal medicine

authors： Larsson K,Ljunghall S,Krusemo UB,Naessén T,Lindh E,Persson I

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:Lipid-lowering drugs as 3-hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase inhibitors and cholestyramine are effective in reducing cardiovascular morbidity both in primary and secondary prevention. Patient compliance is an important determinant of the outcome of therapy. This study was designed to co...

journal_title：Journal of internal medicine

authors： Eriksson M,Hådell K,Holme I,Walldius G,Kjellström T

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVES:The magnitude of cardiovascular risk associated with psoriasis has been debated and the prognostic impact of psoriasis following myocardial infarction (MI) is unknown. Therefore, we investigated the risk of mortality and adverse cardiovascular events in patients with psoriasis following first-time MI. DESIG...

journal_title：Journal of internal medicine

authors： Ahlehoff O,Gislason GH,Lindhardsen J,Olesen JB,Charlot M,Skov L,Torp-Pedersen C,Hansen PR

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:IgA nephropathy (IgAN) is a common complex disease with a strong genetic involvement. We aimed to identify novel, rare, highly penetrant risk variants combining family-based linkage analysis with whole-exome sequencing (WES). METHODS:Linkage analysis of 16 kindreds of South Italian ancestry was performed us...

journal_title：Journal of internal medicine

authors： Cox SN,Pesce F,El-Sayed Moustafa JS,Sallustio F,Serino G,Kkoufou C,Giampetruzzi A,Ancona N,Falchi M,Schena FP,European IgAN Consortium.

更新日期：2017-02-01 00:00:00

abstract：:In a 24-week randomized multicentre single-blind study, including mild to moderate hypertensives free from other diseases, the effect on blood lipids of captopril (n = 51) was studied and compared with that of metoprolol (n = 53). In order to keep the diastolic pressure less than 95 mm Hg, bendroflumethiazide was adde...

journal_title：Journal of internal medicine

authors： Foss OP,Jensen EK

更新日期：1990-02-01 00:00:00

abstract：:The field of nanotechnology has been a significant research focus in the last thirty years. This emphasis is due to the unique optical, electrical, magnetic, chemical and biological properties of materials approximately ten thousand times smaller than the diameter of a hair strand. Researchers have developed methods t...

journal_title：Journal of internal medicine

authors： Sindhwani S,Chan WCW

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:Hypovitaminosis D, a condition that is highly prevalent in older adults aged 65 years and above, is associated with brain changes and dementia. Given the rapidly accumulating and complex contribution of the literature in the field of vitamin D and cognition, clear guidance is needed for researchers and clini...

journal_title：Journal of internal medicine

authors： Annweiler C,Dursun E,Féron F,Gezen-Ak D,Kalueff AV,Littlejohns T,Llewellyn DJ,Millet P,Scott T,Tucker KL,Yilmazer S,Beauchet O

更新日期：2015-01-01 00:00:00

abstract：:Apart from being an acute phase reactant, fibrinogen appears to play an important although not widely recognized role in athero-/thrombogenesis. Arteriosclerotic diseases are associated with elevated levels of plasma fibrinogen. Strategies that lower the cardiovascular risk also lower fibrinogen levels. Virtually all ...

journal_title：Journal of internal medicine

authors： Ernst E

更新日期：1990-06-01 00:00:00

abstract：:In order to study the influence of fish oil on CyA-induced renal dysfunction, 13 patients with psoriasis (CyA group) received cyclosporin A (CyA) alone, and seven patients (CyA/EPA + DHA group) received a combination of cyclosporin A and fish oil (6g eicosapentaenoic acid, C20:5 omega-3, and docosahexaenoic acid, C22:...

journal_title：Journal of internal medicine

authors： Stoof TJ,Korstanje MJ,Bilo HJ,Starink TM,Hulsmans RF,Donker AJ

更新日期：1989-12-01 00:00:00

abstract：OBJECTIVES:The efficacy of octreotide was studied in a group of patients with biochemical evidence of insulinoma. DESIGN:A phase-II study. SETTING:A university department of internal medicine. SUBJECTS:Seven patients with biochemical evidence of insulinoma and without metastatic lesions. INTERVENTION:Daily treatmen...

journal_title：Journal of internal medicine

authors： von Eyben FE,Grodum E,Gjessing HJ,Hagen C,Nielsen H

更新日期：1994-03-01 00:00:00

abstract：:Eleven cases of acetazolamide-associated aplastic anaemia were reported in Sweden during a 17-year period. There were six women and five men with a median age of 71 years (range 63-85 years). The median dose of acetazolamide was 500 mg, and the median duration of treatment was 3 months (range 2-71 months). Ten of the ...

journal_title：Journal of internal medicine

authors： Keisu M,Wiholm BE,Ost A,Mortimer O

更新日期：1990-12-01 00:00:00

abstract：:Atherosclerosis is a silent chronic vascular pathology that is the cause of the majority of cardiovascular ischaemic events. The evolution of vascular disease involves a combination of endothelial dysfunction, extensive lipid deposition in the intima, exacerbated innate and adaptive immune responses, proliferation of ...

journal_title：Journal of internal medicine

authors： Badimon L,Vilahur G

更新日期：2014-12-01 00:00:00

abstract：:The fight against doping in sports commenced as a result of the death of a Danish cyclist during the Rome Olympic Games in 1960. The International Olympic Committee (IOC) established a Medical Commission (IOC-MC) which had the task of designing a strategy to combat the misuse of drugs in Olympic Sport. Some Internatio...

journal_title：Journal of internal medicine

authors： Catlin DH,Fitch KD,Ljungqvist A

更新日期：2008-08-01 00:00:00

abstract：:The syndrome defined as "idiopathic CD4 lymphocytopenia' (ICL) is a rare disease of unknown aetiology, often associated with severe depression of immune defences and the occurrence of opportunistic infections. A case is reported wherein a severe immunodeficiency syndrome with persistent idiopathic CD4+ lymphopenia dev...

journal_title：Journal of internal medicine

authors： Bordin G,Ballaré M,Paglino S,Ravanini P,Dulio D,Malosso MC,Boldorini R,Monteverde A

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:The mechanisms explaining morphological electrocardiogram (ECG) changes and increased troponin T (TnT) in acute stroke are unclear. The aims of the present study were to assess the prevalence of ECG and TnT changes in acute ischaemic stroke, to investigate whether ischaemic-like ECG changes correlate to a ri...

journal_title：Journal of internal medicine

authors： Fure B,Bruun Wyller T,Thommessen B

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Hyponatremia is a common feature of acute illness and associated with increased mortality. This may be explained by a stress-mediated activation of the vasopressin system with an increase in free-water reabsorption. OBJECTIVES:To investigate whether the association between hyponatremia and mortality could b...

journal_title：Journal of internal medicine

authors： Eckart A,Hausfater P,Amin D,Amin A,Haubitz S,Bernard M,Baumgartner A,Struja T,Kutz A,Christ-Crain M,Huber A,Mueller B,Schuetz P

更新日期：2018-09-01 00:00:00

abstract：:Patients with established coronary disease and abnormalities of lipid metabolism represent a particularly important subgroup, since their mortality risk is typically 10 times greater than that amongst-subjects with comparable risk factors but no clinical history. Such patients are commonly treated initially with anti-...

journal_title：Journal of internal medicine

authors： Brown BG,Zhao XQ,Bardsley J,Albers JJ

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVES:To examine whether interleukin-1 receptor antagonist (IL-1Ra) is a predictor for clinically incident diabetes in subjects with metabolic syndrome (MetS) and whether its predictive power is independent of C-reactive protein (CRP), an established marker of inflammation. We further examined whether genetic vari...

journal_title：Journal of internal medicine

authors： Luotola K,Pietilä A,Zeller T,Moilanen L,Kähönen M,Nieminen MS,Kesäniemi YA,Blankenberg S,Jula A,Perola M,Salomaa V,Health 2000 and FINRISK97 Studies.

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to examine the effects of treatment with atorvastatin, alpha-tocopherol and the combination of both, on lipoproteins and oxidative stress in dialysis patients. DESIGN AND SETTING:This double-blind randomised placebo-controlled trial was performed at the dialysis department of...

journal_title：Journal of internal medicine

authors： Diepeveen SH,Verhoeven GW,Van Der Palen J,Dikkeschei LD,Van Tits LJ,Kolsters G,Offerman JJ,Bilo HJ,Stalenhoef AF

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVES:It is well known that pulmonary function is associated with all-cause and cardiovascular (CV) death. Less is known about the association between respiratory symptoms and mortality and whether such an association is independent of physical fitness. In this study, we assessed the association of breathlessness ...

journal_title：Journal of internal medicine

authors： Stavem K,Sandvik L,Erikssen J

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:To describe types of diabetes treatment in a total, adult population, including those on no antidiabetic medication, and to evaluate use of the defined daily doses in estimation of diabetes prevalence. DESIGN:Cross-sectional epidemiologic survey applying patient-based questionnaires and clinical examination...

journal_title：Journal of internal medicine

authors： Midthjell K,Holmen J,Bjørndal A

更新日期：1994-09-01 00:00:00

abstract：:Somatostatin receptors are expressed on the majority of neuroendocrine tumours. The presence of these receptors is clinically useful. First, long-term treatment with somatostatin analogues controls hormonal hypersecretion, which controls flushing attacks, watery diarrhoea, hypoglycaemia and electrolyte disorders in pa...

journal_title：Journal of internal medicine

authors： Lamberts SW,Hofland LJ,Lely AJ,de Herder WW

更新日期：1998-06-01 00:00:00

abstract：:Infection of mural thrombus over an area of old myocardial infarct was found in an elderly woman with cholangitis. This case is unique since cholangitis was thought to be the cause of septicaemia and ventricular aneurysm was not present. ...

journal_title：Journal of internal medicine

authors： Cheung A,Choi A

更新日期：1990-04-01 00:00:00

abstract：:Recent studies have demonstrated that replacement of C-peptide to normal physiological concentrations in insulin-dependent diabetic (IDDM) patients on a short-term basis (1-3 h) results in decreased glomerular hyperfiltration, augmented glucose utilization and improved autonomic nervous function. More prolonged admini...

journal_title：Journal of internal medicine

authors： Wahren J,Johansson BL,Wallberg-Henriksson H,Linde B,Fernqvist-Forbes E,Zierath JR

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVES:The aim was to study the effect of a 5-year diet intervention on 24-year mortality in middle aged men with combined hyperlipidaemia. SETTING:We studied 104 initially healthy men (in 1972) aged 40-49 years with baseline values of total serum cholesterol >6.45 mmol L-1 and fasting triglycerides >2.55 mmol L-1...

journal_title：Journal of internal medicine

authors： Hjerkinn EM,Sandvik L,Hjermann I,Arnesen H

更新日期：2004-01-01 00:00:00

abstract：:Two cases of young healthy males presenting with cardiac tamponade and developing clinical adrenal insufficiency within a few weeks are described. On presentation they had a brisk inflammatory response with complement activation. Both had signs of subclinical hepatitis, and both have later shown evidence of thyroid in...

journal_title：Journal of internal medicine

authors： Torfoss D,von de Lippe E,Jacobsen D

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Gallium-67 (67Ga) scintigraphy may be useful in evaluating patients with retroperitoneal fibrosis (RPF), but a systematic assessment of its value is lacking. OBJECTIVE:Prospective evaluation of the value of 67Ga scintigraphy in assessing active RPF disease and in predicting treatment response. METHODS:Thir...

journal_title：Journal of internal medicine

authors： van Bommel EF,Siemes C,van der Veer SJ,Han SH,Huiskes AW,Hendriksz TR

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:A description of the clinical presentation, diagnostic procedure and mode of therapy in three patients suffering from chronic mesenteric ischaemia. DESIGN AND INTERVENTIONS:In all cases, the diagnosis was made on the basis of abdominal complaints in combination with angiographic findings. The primary treatm...

journal_title：Journal of internal medicine

authors： Hoogenberg K,Van Essen LH,Van den Dungen JJ,Limburg AJ,Boeve WJ,Kleibeuker JH

更新日期：1995-03-01 00:00:00