Prognosis following first-time myocardial infarction in patients with psoriasis: a Danish nationwide cohort study.

Abstract:

OBJECTIVES:The magnitude of cardiovascular risk associated with psoriasis has been debated and the prognostic impact of psoriasis following myocardial infarction (MI) is unknown. Therefore, we investigated the risk of mortality and adverse cardiovascular events in patients with psoriasis following first-time MI. DESIGN, SETTING AND PARTICIPANTS:Cohort study of the entire Danish population including all individuals who experienced first-time MI during the period 2002-2006. Multivariable Cox regression models were used to assess the post-MI prognostic impact of psoriasis. Main outcome measures.  All-cause mortality and a composite cardiovascular end-point of recurrent MI, stroke and cardiovascular death. RESULTS:A total of 462 patients with psoriasis and 48 935 controls (mean age 69.5 and 70.6 years, respectively) were identified with first-time MI during the study period. The mean follow-up was 19.5 months [standard deviation (SD) 16.5] for patients with psoriasis and 22 .0 months (SD 18.7) for those without psoriasis. Incidence rates (IRs) per 1000 patient-years for all-cause mortality were 119.4 [95% confidence interval (CI) 117.2-138.3] and 138.3 (95% CI 114.1-167.7) for patients without and with psoriasis, respectively, and the adjusted hazard ratio (HR) associated with psoriasis was 1.18 (95% CI 0.97-1.43). For the composite end-point, the IRs were 149.7 (95% CI 147.1-152.4) and 185.6 (95% CI 155.8-221.0) for patients without and with psoriasis, respectively, with an HR of 1.26 (95% CI 1.04-1.54) for patients with psoriasis. CONCLUSION:This first study of the impact of psoriasis on prognosis after first-time MI indicated a significantly impaired prognosis in patients with psoriasis. Further studies of this novel association are warranted.

journal_name

J Intern Med

authors

Ahlehoff O,Gislason GH,Lindhardsen J,Olesen JB,Charlot M,Skov L,Torp-Pedersen C,Hansen PR

doi

10.1111/j.1365-2796.2011.02368.x

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

237-44

issue

3

eissn

0954-6820

issn

1365-2796

journal_volume

270

pub_type

杂志文章
  • Calcium absorption and calcium bioavailability.

    abstract::Calcium is important for bone health. It has been customary to focus on dietary calcium intake, but of central importance for the body needs in the individual patient is the actual calcium absorption. This absorption consists of an active vitamin D-mediated component and a passive diffusional component. A number of di...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2796.1992.tb00519.x

    authors: Charles P

    更新日期:1992-02-01 00:00:00

  • Vasopressin: physiology, assessment and osmosensation.

    abstract::Vasopressin (AVP) plays a major role in the regulation of water and sodium homeostasis by its antidiuretic action on the kidney, mediated by V2 receptors. AVP secretion is stimulated by a rise in plasma osmolality, a decline in blood volume or stress. V1a receptors are expressed in vascular smooth muscle cells, but th...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.12645

    authors: Bankir L,Bichet DG,Morgenthaler NG

    更新日期:2017-10-01 00:00:00

  • Hepatitis C in clinical practice.

    abstract::Hepatitis C virus infection is now one of the most important causes of chronic liver disease. Primary care physicians play an important role in the diagnosis and initial work-up of patients infected with this virus. Understanding which patients may be at risk is the first step. By understanding the correct use of hepa...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2796.2001.00781.x

    authors: Larson AM,Carithers RL

    更新日期:2001-02-01 00:00:00

  • Novel tuberculosis vaccination strategies based on understanding the immune response.

    abstract::The current tuberculosis (TB) vaccine bacillus Calmette-Guérin (BCG) fails to protect against adult pulmonary TB. Yet, its capacity to control miliary TB in newborn infants forms the basis for development of novel vaccine candidates. These either exploit genetic modification of BCG to create a viable replacement vacci...

    journal_title:Journal of internal medicine

    pub_type: 历史文章,杂志文章

    doi:10.1111/j.1365-2796.2010.02216.x

    authors: Kaufmann SH

    更新日期:2010-04-01 00:00:00

  • Plasma fibrinogen--an independent cardiovascular risk factor.

    abstract::Apart from being an acute phase reactant, fibrinogen appears to play an important although not widely recognized role in athero-/thrombogenesis. Arteriosclerotic diseases are associated with elevated levels of plasma fibrinogen. Strategies that lower the cardiovascular risk also lower fibrinogen levels. Virtually all ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2796.1990.tb00174.x

    authors: Ernst E

    更新日期:1990-06-01 00:00:00

  • Habitual diet, platelet function, fibrinogen and factor VII coagulant activity in young Finns.

    abstract:OBJECTIVES:The objective of the study was to determine whether an association between diet and platelet function, plasma fibrinogen level and factor VII coagulant activity (VII:C) could be established in young subjects. DESIGN:Data on the habitual diet of the subjects were collected either by a questionnaire on food h...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1995.tb00888.x

    authors: Mutanen M,Krusius T,Räsänen L,Freese R,Vahtera E,Viikari JS

    更新日期:1995-06-01 00:00:00

  • The association between neutrophil gelatinase-associated lipocalin and clinical outcome in chronic heart failure: results from CORONA*.

    abstract:OBJECTIVE:To study the prognostic value of neutrophil gelatinase-associated lipocalin (NGAL) in chronic heart failure (HF) of ischaemic aetiology. BACKGROUND:Neutrophil gelatinase-associated lipocalin is a marker of kidney injury as well as matrix degradation and inflammation and has previously been shown to be increa...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2796.2011.02503.x

    authors: Nymo SH,Ueland T,Askevold ET,Flo TH,Kjekshus J,Hulthe J,Wikstrand J,McMurray J,Van Veldhuisen DJ,Gullestad L,Aukrust P,Yndestad A

    更新日期:2012-05-01 00:00:00

  • The NeiI polymorphism in the cyclin D1 gene and sporadic primary hyperparathyroidism.

    abstract:OBJECTIVES:The cell cycle regulator cyclin D1 plays an important role in parathyroid tumourigenesis. The NciI polymorphism in exon 4 has recently been associated with early onset of hereditary nonpolyposis colorectal cancer and is a prognostic indicator of nonsmall cell lung cancer and squamous cell carcinomas. Further...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.2001.00912.x

    authors: Correa P,Lundgren E,Rastad J,Akerström G,Westin G,Carling T

    更新日期:2001-12-01 00:00:00

  • Helicobacter pylori: resurrection of the cancer link.

    abstract::Helicobacter pylori is one of the most common pathogenic bacterial infections, colonizing an estimated half of all humans. In a subset of individuals, the infection leads to serious gastroduodenal disease such as peptic ulcers and gastric adenocarcinoma. The factors contributing to skewing this, in most cases benign, ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2796.2003.01119.x

    authors: Björkholm B,Falk P,Engstrand L,Nyrén O

    更新日期:2003-02-01 00:00:00

  • The dysmetabolic syndrome.

    abstract::The first unifying definition for the metabolic syndrome was proposed by WHO in 1998. In accordance to this, patients with type 2 diabetes mellitus or impaired glucose tolerance have the syndrome if they fulfil two of the criteria: hypertension, dyslipidaemia, obesity/abdominal obesity and microalbuminuria. Persons wi...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1046/j.1365-2796.2001.00864.x

    authors: Groop L,Orho-Melander M

    更新日期:2001-08-01 00:00:00

  • Review of 103 Swedish Healthcare Quality Registries.

    abstract:BACKGROUND AND OBJECTIVES:In the past two decades, an increasing number of nationwide, Swedish Healthcare Quality Registries (QRs) focusing on specific disorders have been initiated, mostly by physicians. Here, we describe the purpose, organization, variables, coverage and completeness of 103 Swedish QRs. METHODS:From...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.12303

    authors: Emilsson L,Lindahl B,Köster M,Lambe M,Ludvigsson JF

    更新日期:2015-01-01 00:00:00

  • Impact of a high-dose nitrate strategy on cardiac stress in acute heart failure: a pilot study.

    abstract:BACKGROUND:Intravenous nitrate therapy has been shown to improve short-term outcome of acute heart failure patients treated in the intensive care unit. The potential of a noninvasive high-dose nitrate strategy in the Emergency Department and the general ward remains unknown. METHODS:A total of 128 consecutive acute he...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2009.02146.x

    authors: Breidthardt T,Noveanu M,Potocki M,Reichlin T,Egli P,Hartwiger S,Socrates T,Gayat E,Christ M,Mebazaa A,Mueller C

    更新日期:2010-03-01 00:00:00

  • Eighty-year-old men without cardiovascular disease in the community of Malmö. Part I. Social and medical factors, with special reference to the lipoprotein pattern.

    abstract::A total of 1280 80-year-old men were invited to a medical examination to study common risk indicators for cardiovascular disease (CVD) in the elderly. From the pool of 811 responders (63.3%), all 122 individuals who fulfilled our inclusion criteria were assigned to one of four groups: (1) no CVD, non-smokers; (2) no C...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1990.tb00185.x

    authors: Stavenow L,Elmståhl S,Jerntorp P,Nilsson-Ehle P,Pessah-Rasmussen H,Galvard H,Hansen F,Samuelsson SM

    更新日期:1990-07-01 00:00:00

  • A genetic polymorphism in connexin 37 as a prognostic marker for atherosclerotic plaque development.

    abstract:BACKGROUND AND OBJECTIVES:Atherosclerosis is a multifactorial disease, in part characterized by chronic inflammatory changes in the vessel wall and loss of normal physical and biochemical interactions between endothelial cells and smooth muscle cells. Previous studies [Hu J., Cotgreave IA. J Clin Invest; 99: 1-5] have ...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.1999.00564.x

    authors: Boerma M,Forsberg L,Van Zeijl L,Morgenstern R,De Faire U,Lemne C,Erlinge D,Thulin T,Hong Y,Cotgreave IA

    更新日期:1999-08-01 00:00:00

  • Studies on patients establish Crohn's disease as a manifestation of impaired innate immunity.

    abstract::The fruitless search for the cause of Crohn's disease has been conducted for more than a century. Various theories, including autoimmunity, mycobacterial infection and aberrant response to food and other ingested materials, have been abandoned for lack of robust proof. This review will provide the evidence, obtained f...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1111/joim.12945

    authors: Segal AW

    更新日期:2019-10-01 00:00:00

  • A plasma glucose concentration below 2.5 mmol L-1 is not an appropriate criterion to end the 72-h fast.

    abstract:CONTEXT:The classical end-point to terminate the 72-h fast in a patient evaluated for a hypoglycaemic disorder is the occurrence of hypoglycaemic symptoms in association with a low plasma glucose level. However, neither the symptoms nor the plasma glucose level have been exactly defined. OBJECTIVE:To determine whether...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.2002.01060.x

    authors: Wiesli P,Brändle M,Schwegler B,Lehmann R,Spinas GA,Schmid C

    更新日期:2002-12-01 00:00:00

  • Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.

    abstract::Primary adrenal insufficiency (PAI), or Addison's disease, is a rare, potentially deadly, but treatable disease. Most cases of PAI are caused by autoimmune destruction of the adrenal cortex. Consequently, patients with PAI are at higher risk of developing other autoimmune diseases. The diagnosis of PAI is often delaye...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,实务指引,评审

    doi:10.1111/joim.12162

    authors: Husebye ES,Allolio B,Arlt W,Badenhoop K,Bensing S,Betterle C,Falorni A,Gan EH,Hulting AL,Kasperlik-Zaluska A,Kämpe O,Løvås K,Meyer G,Pearce SH

    更新日期:2014-02-01 00:00:00

  • Diabetes mellitus is a strong negative prognostic factor in patients with myocardial infarction treated with thrombolytic therapy.

    abstract:OBJECTIVES:To assess the long-term prognostic values of baseline demographic data, occurrence of vectorcardiographic signs of reperfusion, left ventricular function and coronary angiographic features. DESIGN:Longitudinal study of morbidity and mortality. SETTING:Coronary care unit at Danderyd Hospital, Stockholm, Swe...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.2000.00007.x

    authors: Strandberg LE,Ericsson CG,O'Konor ML,Bergstrand L,Lundin P,Rehnqvist N,Tornvall P

    更新日期:2000-08-01 00:00:00

  • The role of microRNA in nutritional control.

    abstract::MicroRNAs (miRNAs) are one of a growing class of noncoding RNAs that are involved in the regulation of a wide range of metabolic processes including cellular differentiation, cell proliferation and apoptosis. The generation of miRNA is regulated in complex ways, for example by small interfering RNAs (small nucleolar a...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/joim.12372

    authors: Nolte-'t Hoen EN,Van Rooij E,Bushell M,Zhang CY,Dashwood RH,James WP,Harris C,Baltimore D

    更新日期:2015-08-01 00:00:00

  • Periodontal disease is associated with carotid plaque area: the Malmö Offspring Dental Study (MODS).

    abstract:BACKGROUND:Periodontal disease is associated with cardiovascular disease (CVD) but it is unknown if periodontal disease severity is associated with asymptomatic carotid plaque. The aim of the current population-based, observational study was to investigate if signs of periodontal disease are associated with the occurre...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/joim.12998

    authors: Jönsson D,Orho-Melander M,Demmer RT,Engström G,Melander O,Klinge B,Nilsson PM

    更新日期:2020-03-01 00:00:00

  • Physical activity in relation to indices of endothelial function and angiogenesis factors in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).

    abstract:BACKGROUND:Hypertension is an important risk factor for cardiovascular disease. The latest guidelines recommend regular physical exercise as initial step or adjunct in the treatment of hypertension. We investigated the association between physical activity and the degree of hypertension, as well as the relation to indi...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.2003.01087.x

    authors: Felmeden DC,Spencer CG,Blann AD,Beevers DG,Lip GY

    更新日期:2003-01-01 00:00:00

  • Localized tuberculosis of the oesophagus: a rare condition.

    abstract::This report describes the case of a male patient with progressive dysphagia, epigastric pain, odynophagia, generalized weakness and a mid-oesophagus ulceration in which biopsies showed acid-fast bacilli and histological evidence of tuberculosis. Culture of the biopsies and the sputum revealed mycobacterium tuberculosi...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1995.tb00902.x

    authors: Leotta SM,Elsborg L

    更新日期:1995-07-01 00:00:00

  • Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis.

    abstract:BACKGROUND:Elevated plasma levels of bilirubin, an endogenous antioxidant, have been associated with reduced risk of ischaemic heart disease (IHD) and myocardial infarction (MI). Whether this is a causal relationship remains unclear. OBJECTIVE:We tested the hypothesis that elevated plasma bilirubin is causally related...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章,meta分析

    doi:10.1111/j.1365-2796.2012.02576.x

    authors: Stender S,Frikke-Schmidt R,Nordestgaard BG,Grande P,Tybjaerg-Hansen A

    更新日期:2013-01-01 00:00:00

  • The risk of ipsilateral versus contralateral recurrent deep vein thrombosis in the leg. The DURAC Trial Study Group.

    abstract:OBJECTIVES:To investigate the risk of ipsilateral versus contralateral recurrent deep vein thrombosis in the leg. DESIGN:An open prospective long term follow-up multicentre trial. Patients were followed by frequent outpatient visits at each centre during the first 12 months after inclusion and thereafter annually. SE...

    journal_title:Journal of internal medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1046/j.1365-2796.2000.00662.x

    authors: Lindmarker P,Schulman S

    更新日期:2000-05-01 00:00:00

  • The risk of hip fractures in patients with primary hyperparathyroidism: a population-based cohort study with a follow-up of 19 years.

    abstract:OBJECTIVE:To evaluate primary hyperparathyroidism (HPT) as a risk factor for hip fractures. DESIGN:A population-based, record-linked, prospective study with a mean observation time of 17 years (women) and 16.5 years (men). SETTING:A cohort obtained from a register of hospital admissions in the Uppsala Health Care Reg...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1993.tb01017.x

    authors: Larsson K,Ljunghall S,Krusemo UB,Naessén T,Lindh E,Persson I

    更新日期:1993-12-01 00:00:00

  • Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19.

    abstract:BACKGROUND:Bile acid (BA) synthesis is essential in cholesterol and lipid homoeostasis. METHODS:Serum samples from 435 normal and 23 cholecystectomized subjects were obtained after overnight fasting and assayed for markers of BA and cholesterol synthesis, as well as cholesterol absorption. We determined whether BA syn...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2011.02466.x

    authors: Gälman C,Angelin B,Rudling M

    更新日期:2011-12-01 00:00:00

  • Rapid Emergency Medicine score: a new prognostic tool for in-hospital mortality in nonsurgical emergency department patients.

    abstract:OBJECTIVES:To evaluate the predictive accuracy of the scoring system Rapid Acute Physiology score (RAPS) in nonsurgical patients attending the emergency department (ED) regarding in-hospital mortality and length of stay in hospital (LOS), and to investigate whether the predictive ability of RAPS could be improved by ex...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.2004.01321.x

    authors: Olsson T,Terent A,Lind L

    更新日期:2004-05-01 00:00:00

  • A patient with osteomalacia as single presenting symptom of gluten-sensitive enteropathy.

    abstract::A 59-year-old male patient presented with invalidating osteomalacia of 2.5 years' duration. The osteomalacia was caused by severe malabsorption due to gluten-sensitive enteropathy (GSE). There were no other signs or symptoms of GSE in this patient. Clinical presentation with monosymptomatic osteomalacia is very unusua...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1992.tb00554.x

    authors: De Boer WA,Tytgat GN

    更新日期:1992-07-01 00:00:00

  • Do drug costs affect physicians' prescription decisions?

    abstract:OBJECTIVE:To study the impact of the cost of pharmaceuticals on physicians' decisions about drug prescription. DESIGN:A simulation protocol for the treatment of two patients, one with mild and the other with a severe form of urinary tract infection (UTI), was designed. Thirty family physicians in outpatient clinics an...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1365-2796.1997.137143000.x

    authors: Hart J,Salman H,Bergman M,Neuman V,Rudniki C,Gilenberg D,Matalon A,Djaldetti M

    更新日期:1997-05-01 00:00:00

  • Erythropoietin deficiency in acute crescentic glomerulonephritis and in total bilateral renal cortical necrosis.

    abstract::Six patients with acute renal failure, in five cases due to acute crescentic glomerulonephritis and in one case due to total bilateral renal cortical necrosis, were studied. All had serum erythropoietin (EPO) concentrations in the normal range, despite a relatively severe anaemia. Half-life and plasma clearance of int...

    journal_title:Journal of internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1365-2796.1991.tb00360.x

    authors: Thaysen JH,Nielsen OJ,Brandi L,Szpirt W

    更新日期:1991-04-01 00:00:00