Prognosis following first-time myocardial infarction in patients with psoriasis: a Danish nationwide cohort study.

abstract：:The current tuberculosis (TB) vaccine bacillus Calmette-Guérin (BCG) fails to protect against adult pulmonary TB. Yet, its capacity to control miliary TB in newborn infants forms the basis for development of novel vaccine candidates. These either exploit genetic modification of BCG to create a viable replacement vacci...

journal_title：Journal of internal medicine

authors： Kaufmann SH

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the impact of hypertension and other risk factors on mortality, in particular cardiovascular mortality, in a geographically defined population of elderly subjects. DESIGN:An observational 25-year study of a total population. SETTING:The local health centre in the village of Dalby in southern Sw...

journal_title：Journal of internal medicine

authors： Lidfeldt J,Lanke J,Sundquist J,Lindholm LH

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to quantify the inter-relationship between bone mineral density and physical activity, muscle strength, and body mass composition in a group of healthy 16-20-year-old women. DESIGN:A cross-sectional study. SETTING:Reykjavik area. SUBJECTS:Two-hundred and fifty-four Icelandic Caucas...

journal_title：Journal of internal medicine

authors： Valdimarsson O,Kristinsson JO,Stefansson SO,Valdimarsson S,Sigurdsson G

更新日期：1999-05-01 00:00:00

abstract：:Cancer is a genetic disease caused by 'gain of function' mutations of oncogenes and 'loss of function' mutations of tumour suppressors and of genes involved in DNA repair mechanisms. The RET gene encodes a tyrosine kinase receptor for molecules belonging to the glial cell line-derived neurotrophic factor (GDNF) family...

journal_title：Journal of internal medicine

authors： Santoro M,Melillo RM,Carlomagno F,Visconti R,De Vita G,Salvatore G,Lupoli G,Fusco A,Vecchio G

更新日期：1998-06-01 00:00:00

abstract：:The association of sex, age, relative weight, smoking and drinking habits, chronic obstructive pulmonary disease (COPD) and economic and marital status, with benign oesophageal disease (BOD) was investigated by means of a point-prevalence study of BOD in a Danish population. A total of 346 individuals, representing su...

journal_title：Journal of internal medicine

authors： Andersen LI,Jensen G

更新日期：1991-07-01 00:00:00

abstract：:Coeliac disease (CD) and noncoeliac wheat or gluten sensitivity (NCWS/NCGS) are common gluten-related disorders. Both conditions can present with gastrointestinal and extraintestinal manifestations, which can be a challenge for physicians to discern between. Whilst coeliac serology and histological assessment are requ...

journal_title：Journal of internal medicine

authors： Rej A,Aziz I,Sanders DS

更新日期：2020-11-01 00:00:00

abstract：:During the long history of development of haemoglobin (Hb)-based O2 carriers (HBOCs), many side effects of Hb molecules have become apparent. They imply the physiological importance of the cellular structure of red blood cells. Hb-vesicles (HbV) are artificial O2 carriers that encapsulate concentrated Hb solution with...

journal_title：Journal of internal medicine

authors： Sakai H,Sou K,Horinouchi H,Kobayashi K,Tsuchida E

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:To compare foreign- and Swedish-born diabetic subjects regarding health care utilization, complications, clinical and socio-economic characteristics. DESIGN:Cross-sectional study. SETTING:All known diabetic patients living in six defined primary health care districts. SUBJECTS:Of 1861 identified subjects ...

journal_title：Journal of internal medicine

authors： Hjelm K,Apelqvist J,Nyberg P,Sundquist J,Isacsson A

更新日期：1997-08-01 00:00:00

abstract：:Left ventricular filling pattern was assessed by pulsed Doppler echocardiography at rest and during handgrip exercise in 33 healthy middle-aged subjects. The peak mitral flow-velocities during the early rapid filling phase (E) and during late (atrial) filling (A) were measured and the ratio of these peak flow-velociti...

journal_title：Journal of internal medicine

authors： Airaksinen KE,Ikäheimo MJ,Huikuri HV,Koistinen MJ,Linnaluoto M,Takkunen JT

更新日期：1989-10-01 00:00:00

abstract：:Hepatitis C virus infection is now one of the most important causes of chronic liver disease. Primary care physicians play an important role in the diagnosis and initial work-up of patients infected with this virus. Understanding which patients may be at risk is the first step. By understanding the correct use of hepa...

journal_title：Journal of internal medicine

authors： Larson AM,Carithers RL

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:To assess the clinical course of renal function in relation to risk factors in NIDDM patients with normo- and microalbuminuria. DESIGN:Prospective clinical study. SETTING:Outpatient diabetic clinic. SUBJECTS:Thirty-two NIDDM patients with normo- or microalbuminuria followed for (mean (range)) 5.5 (3.3-7.5...

journal_title：Journal of internal medicine

authors： Nielsen S,Schmitz A,Rehling M,Mogensen CE

更新日期：1997-02-01 00:00:00

abstract：:Current orthodoxy states that coronary heart disease results from the unhealthy lifestyles of westernized adults together with a contribution from genetic inheritance. This does not provide a secure basis for prevention of the disease. Geographical studies gave the first clue that the disease originates during intra-u...

journal_title：Journal of internal medicine

authors： Barker DJ

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Phospholipid transfer protein (PLTP) is an emerging cardiometabolic risk marker that is important in high-density lipoprotein (HDL) and triglyceride metabolism. Plasma PLTP activity is elevated in type 2 diabetes mellitus, whereas glucose may regulate PLTP gene transcription in vitro. Of interest, common PLT...

journal_title：Journal of internal medicine

authors： Dullaart RP,Vergeer M,de Vries R,Kappelle PJ,Dallinga-Thie GM

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:In this study, we explore the associations of decreased thyroid hormone levels with inflammation, wasting and survival in biochemically euthyroid patients with end-stage renal disease (ESRD). DESIGN:After exclusion of 23 patients with thyroid-stimulating hormone (TSH) values outside the normal range (0.1-4....

journal_title：Journal of internal medicine

authors： Carrero JJ,Qureshi AR,Axelsson J,Yilmaz MI,Rehnmark S,Witt MR,Bárány P,Heimbürger O,Suliman ME,Alvestrand A,Lindholm B,Stenvinkel P

更新日期：2007-12-01 00:00:00

abstract：:Cardiac troponin assays have become more sensitive over the years leading to the clinical introduction of high-sensitivity cardiac troponin assays in 2010. Their use has revolutionized the assessment of patients with chest pain in the emergency department by allowing earlier rule-in and rule-out of myocardial infarcti...

journal_title：Journal of internal medicine

authors： Holzmann MJ

更新日期：2018-07-01 00:00:00

abstract：:Cardiac pheochromocytoma is a rare tumour and may be difficult to localize. We present a 32-year-old male with a cardiac pheochromocytoma that was successfully resected. An initial unenhanced CT did not reveal the tumour. MIBG-scintigraphy indicated the location, but to get full information, a dynamic contrast-enhance...

journal_title：Journal of internal medicine

authors： Jönsson A,Hallengren B,Manhem P,Lilja B,Stavenow L,Ståhl E,Törnquist C

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to identify predictors of weight loss in obese men participating in a 2-year behaviour modification programme. DESIGN:Longitudinal, clinical intervention study of a behaviour modifying weight loss program. SETTING:University Hospital, Stockholm, Sweden. SUBJECTS:Forty-four ...

journal_title：Journal of internal medicine

authors： Näslund E,Andersson I,Degerblad M,Kogner P,Kral JG,Rössner S,Hellström PM

更新日期：2000-10-01 00:00:00

abstract：:The first unifying definition for the metabolic syndrome was proposed by WHO in 1998. In accordance to this, patients with type 2 diabetes mellitus or impaired glucose tolerance have the syndrome if they fulfil two of the criteria: hypertension, dyslipidaemia, obesity/abdominal obesity and microalbuminuria. Persons wi...

journal_title：Journal of internal medicine

authors： Groop L,Orho-Melander M

更新日期：2001-08-01 00:00:00

abstract：:In order to evaluate the effects of one-year antihypertensive treatment on plasma lipids and lipoproteins, 65 patients whose diastolic blood pressure was in the range 95-120 mmHg were randomly allocated to groups that received either hydrochlorothiazide or metoprolol, or both drugs when the response to one of them was...

journal_title：Journal of internal medicine

authors： Monmany J,Domingo P,Gomez JA,Sanz F,Roca-Cusachs A,Nolla J,Jane F

更新日期：1990-10-01 00:00:00

abstract：:A 42-year-old man presented with a mediastinal tumour. On histological examination, tuberculosis was evoked, but no definitive conclusion could be drawn. The patient thereafter developed throat ulcerations and rapidly progressing renal insufficiency due to necrotizing glomerulonephritis. After reviewing the histologic...

journal_title：Journal of internal medicine

authors： Boudes P

更新日期：1990-03-01 00:00:00

abstract：:MicroRNAs (miRNAs) are one of a growing class of noncoding RNAs that are involved in the regulation of a wide range of metabolic processes including cellular differentiation, cell proliferation and apoptosis. The generation of miRNA is regulated in complex ways, for example by small interfering RNAs (small nucleolar a...

journal_title：Journal of internal medicine

authors： Nolte-'t Hoen EN,Van Rooij E,Bushell M,Zhang CY,Dashwood RH,James WP,Harris C,Baltimore D

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:To assess the coexistence of hypertension and diabetes, associations with cardiovascular risk factors and the achievement of current treatment goals. DESIGN:A community-based, cross-sectional, observational study. SETTING:Hypertension and diabetes outpatient clinics in primary health care, Skara, Sweden. ...

journal_title：Journal of internal medicine

authors： Bøg-Hansen E,Lindblad U,Bengtsson K,Ranstam J,Melander A,Råstam L

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVES:Hypocitraturia is a risk factor for calcium nephrolithiasis. 1,25(OH)2D3 influences renal citrate handling and enhances citraturia. The aim of this study was to evaluate the relationship between vitamin D receptor (VDR) allelic variant and urinary citrate excretion in recurrent stone formers (SF) patients. ...

journal_title：Journal of internal medicine

authors： Mossetti G,Vuotto P,Rendina D,Numis FG,Viceconti R,Giordano F,Cioffi M,Scopacasa F,Nunziata V

更新日期：2003-02-01 00:00:00

abstract：:During a 10-year period 39 patients with acromegaly, aged 23-73 years, underwent selective adenomectomy via a trans-sphenoidal or transfrontal (one case) approach. Six to 12 months after the operation, the serum level of growth hormone (GH) was reduced to less than 5 micrograms l-1 in 28 patients (74%) in at least two...

journal_title：Journal of internal medicine

authors： Valdemarsson S,Bramnert M,Cronquist S,Elner A,Eneroth CM,Hedner P,Lindvall-Axelsson M,Nordström CH,Strömblad LG

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVES:Atherosclerosis is an inflammatory disease of the arterial wall that leads to myocardial infarction and stroke. Regulatory T cells (Tregs) and IL-10 exert significant anti-atherogenic effects in experimental models of atherosclerosis by modulating vascular inflammation. We have previously shown that Mycobact...

journal_title：Journal of internal medicine

authors： Ovchinnikova OA,Berge N,Kang C,Urien C,Ketelhuth DF,Pottier J,Drouet L,Hansson GK,Marchal G,Bäck M,Schwartz-Cornil I,Lagranderie M

更新日期：2014-01-01 00:00:00

abstract：:Seventeen patients with mild to moderate hypertension, as indicated by a diastolic blood pressure (DPB) of 95-115 mmHg (WHO I), were treated in a randomized, double-blind, parallel study, with either 5 mg of fosinopril, a new phosphinic acid-containing angiotensin converting enzyme (ACE) inhibitor, or 25 mg of hydroch...

journal_title：Journal of internal medicine

authors： Forslund T,Franzén P,Backman R

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVE:To investigate the demographic, clinical, biochemical and genotypic features of patients with erythropoietic protoporphyria (EPP) in a Swedish cohort. DESIGN:Cross-sectional questionnaire, biochemical and genetic study. SETTING:Sweden. SUBJECTS:Fifty-one Swedish individuals known in 2008 to have EPP confir...

journal_title：Journal of internal medicine

authors： Wahlin S,Floderus Y,Stål P,Harper P

更新日期：2011-03-01 00:00:00

abstract：:We created the GIFTs, fusions of granulocyte-colony macrophage-stimulating-factor with IL-2, or IL-15 or IL-21, in order to stimulate distinct, but complimentary elements of the immune response. We found that the physical coupling of two functionally distinct cytokines as a bifunctional hybrid allowed for synergistic ...

journal_title：Journal of internal medicine

authors： Williams P,Galipeau J

更新日期：2011-01-01 00:00:00

abstract：:Ebola virus disease (EVD) is a zoonotic disease that causes severe haemorrhagic fever, with high fatality rates of up to 90% in humans. Today, there is no effective treatment available. Person-to-person transmission occurs through exposure to blood or body fluids, which can threaten other household members and first-l...

journal_title：Journal of internal medicine

authors： Mirazimi A

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Waist circumference is a clinical marker of obesity and an established risk factor for cardiovascular (CV) disease. Adiponectin, an adipocyte-derived hormone and new biomarker of obesity, was recently proposed as the missing link between obesity and increased cardiovascular risk. We evaluated waist and adipon...

journal_title：Journal of internal medicine

authors： Holewijn S,den Heijer M,van Tits LJ,Swinkels DW,Stalenhoef AF,de Graaf J

更新日期：2010-06-01 00:00:00