The risk of hip fractures in patients with primary hyperparathyroidism: a population-based cohort study with a follow-up of 19 years.

abstract：:Ten adult patients with a severe nephrotic syndrome resistant to conventional immunosuppression were treated with cyclosporin A (CyA) for a mean period of 11 months. CyA was effective in all but two patients, as evaluated by 24-h urine protein excretion and clinical appearance. In general the best effect of CyA was se...

journal_title：Journal of internal medicine

authors： Nyrop M,Olgaard K

更新日期：1990-01-01 00:00:00

abstract：:Orthopaedic implants are highly susceptible to infection. The aims of treatment of infection associated with internal fixation devices are fracture consolidation and prevention of chronic osteomyelitis. Complete biofilm eradication is not the primary goal, as remaining adherent microorganisms can be removed with the d...

journal_title：Journal of internal medicine

authors： Zimmerli W

更新日期：2014-08-01 00:00:00

abstract：:Six patients with acute renal failure, in five cases due to acute crescentic glomerulonephritis and in one case due to total bilateral renal cortical necrosis, were studied. All had serum erythropoietin (EPO) concentrations in the normal range, despite a relatively severe anaemia. Half-life and plasma clearance of int...

journal_title：Journal of internal medicine

authors： Thaysen JH,Nielsen OJ,Brandi L,Szpirt W

更新日期：1991-04-01 00:00:00

abstract：:Neutrophil granules store proteins that are critically important for the neutrophil to move from the vascular bed to tissues and to kill microorganisms. This is illustrated in nature when individual proteins are deleted due to inherited mutations of their cognate genes, and such deficiencies result in the conditions l...

journal_title：Journal of internal medicine

authors： Häger M,Cowland JB,Borregaard N

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:To study serum homocysteine concentration for its prediction of major coronary heart disease events amongst women. DESIGN:A case-control study nested within a follow-up study. Subjects. A total of 74 and 75 major coronary events (coronary deaths or nonfatal myocardial infarction) which occurred in women wit...

journal_title：Journal of internal medicine

authors： Knekt P,Alfthan G,Aromaa A,Heliövaara M,Marniemi J,Rissanen H,Reunanen A

更新日期：2001-05-01 00:00:00

abstract：AIM:Prevalence, optimal diagnostic approach and consequences of clinically unsuspected osteomyelitis in diabetic foot ulcers are unclear. Early diagnosis of this infection may be crucial to ensure correct management. METHODS:We conducted a prospective study in 20 diabetic patients with a chronic foot ulcer (>8 weeks) ...

journal_title：Journal of internal medicine

authors： Schwegler B,Stumpe KD,Weishaupt D,Strobel K,Spinas GA,von Schulthess GK,Hodler J,Böni T,Donath MY

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Hyponatremia is a common feature of acute illness and associated with increased mortality. This may be explained by a stress-mediated activation of the vasopressin system with an increase in free-water reabsorption. OBJECTIVES:To investigate whether the association between hyponatremia and mortality could b...

journal_title：Journal of internal medicine

authors： Eckart A,Hausfater P,Amin D,Amin A,Haubitz S,Bernard M,Baumgartner A,Struja T,Kutz A,Christ-Crain M,Huber A,Mueller B,Schuetz P

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:the results of experimental studies suggest that vitamin D deficiency activates the renin-angiotensin system and predisposes to hypertension. Results of previous epidemiological studies investigating the association between 25-hydroxyvitamin D [25(OH)D] status and hypertension have not been consistent, perha...

journal_title：Journal of internal medicine

authors： Burgaz A,Byberg L,Rautiainen S,Orsini N,Håkansson N,Arnlöv J,Sundström J,Lind L,Melhus H,Michaëlsson K,Wolk A

更新日期：2011-02-01 00:00:00

abstract：:A young, apparently healthy, soldier developed acute muscle weakness and rhabdomyolysis following prolonged exercise. The resultant myoglobinuria caused severe acute renal failure. Further investigation revealed the presence of carnitine palmitoyltransferase deficiency as the cause of the rhabdomyolysis. Renal functio...

journal_title：Journal of internal medicine

authors： Berkman N,Meirow D,Katzir Z,Bar-On H

更新日期：1993-03-01 00:00:00

abstract：:Pneumonia exhibits a broad range of severity, from mildly symptomatic at one end to fulminant septic shock and death at the other. Although an adequate inflammatory response is necessary for the clearance of microorganisms, excessive inflammation can lead to ongoing local and systemic damage. Because of this extended ...

journal_title：Journal of internal medicine

authors： Meijvis SC,van de Garde EM,Rijkers GT,Bos WJ

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To assess the relationships between circulating levels of proinflammatory cytokines and adrenocortical hormones and leptin early after stroke. DESIGN:Blood samples were collected four times daily the first two days after stroke, twice daily the next 4 days and four times at day 7. Cognitive function and func...

journal_title：Journal of internal medicine

authors： Johansson A,Ahrén B,Näsman B,Carlström K,Olsson T

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:To study the association between postural hypotension and (i) electrolyte levels and (ii) neurohumoral factors in elderly hypertensive patients using diuretics. DESIGN:Cross-sectional study of patients and controls. SETTING:The subjects were gathered from senior citizen clubs or they were referred to the st...

journal_title：Journal of internal medicine

authors： Luutonen S,Neuvonen P,Ruskoaho H,Räihä I,Rajala T,Antila K,Sourander L

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:There is growing evidence that endogenous hypertriglyceridaemia is frequently accompanied by a state of insulin resistance. The present study was performed to determine whether patients with primary endogenous hypertriglyceridaemia commonly have abnormalities in plasma concentrations and turnover rates of fre...

journal_title：Journal of internal medicine

authors： Mostaza JM,Vega GL,Snell P,Grundy SM

更新日期：1998-04-01 00:00:00

abstract：:Recent observed changes in Earth's climate, to which humans have contributed substantially, are affecting various health outcomes. These include altered distributions of some infectious disease vectors (ticks at high latitudes, malaria mosquitoes at high altitudes), and an uptrend in extreme weather events and associa...

journal_title：Journal of internal medicine

authors： McMichael AJ,Lindgren E

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:Patients with psoriasis are prone to premature atherosclerosis and increased risk of cardiovascular disease events. However, the prevalence and extent of atherosclerosis in patients with psoriasis are unknown. DESIGN:A cross-sectional study. SETTING AND SUBJECTS:The prevalence and extent of coronary and car...

journal_title：Journal of internal medicine

authors： Yiu KH,Yeung CK,Zhao CT,Chan JC,Siu CW,Tam S,Wong CS,Yan GH,Yue WS,Khong PL,Chan HH,Tse HF

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:Patients undergoing bariatric surgery present long-term metabolic improvements and reduced type 2 diabetes risk, despite long-term weight regain. We hypothesized that part of these protective effects could be linked to altered gene expression in white adipose tissue (WAT). METHODS:Transcriptomic profiling by...

journal_title：Journal of internal medicine

authors： Kerr AG,Andersson DP,Rydén M,Arner P,Dahlman I

更新日期：2020-08-01 00:00:00

abstract：:A major challenge in the growing field of bioelectronic medicine is the development of tissue interface technologies promoting device integration with biological tissues. Materials based on organic bioelectronics show great promise due to a unique combination of electronic and ionic conductivity properties. In this re...

journal_title：Journal of internal medicine

authors： Löffler S,Melican K,Nilsson KPR,Richter-Dahlfors A

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Mixed cryoglobulinaemia (MC) and autoimmune chronic hepatitis (AI-CH) are frequently associated with hepatitis C virus (HCV) chronic infection. Because HCV represents a possible common aetiological factor, the aim of the present study is to investigate the clinico-serological alterations of both MC and AI-CH...

journal_title：Journal of internal medicine

authors： Ferri C,Longombardo G,La Civita L,Greco F,Lombardini F,Cecchetti R,Cagianelli MA,Marchi S,Monti M,Zignego AL

更新日期：1994-07-01 00:00:00

abstract：:MicroRNAs (miRNAs) are one of a growing class of noncoding RNAs that are involved in the regulation of a wide range of metabolic processes including cellular differentiation, cell proliferation and apoptosis. The generation of miRNA is regulated in complex ways, for example by small interfering RNAs (small nucleolar a...

journal_title：Journal of internal medicine

authors： Nolte-'t Hoen EN,Van Rooij E,Bushell M,Zhang CY,Dashwood RH,James WP,Harris C,Baltimore D

更新日期：2015-08-01 00:00:00

abstract：:The ground-breaking discovery of genotype-phenotype relationships in hereditary medullary thyroid cancer has greatly facilitated early prophylactic thyroidectomy. Its timing depends not solely on a positive gene test but, more importantly, on the type of the REarranged during Transfection (RET) mutation and its underl...

journal_title：Journal of internal medicine

authors： Machens A,Lorenz K,Dralle H

更新日期：2009-07-01 00:00:00

abstract：:Multiple sclerosis (MS), a chronic inflammatory demyelinating and neurodegenerative disease of the central nervous system, is today a leading cause of unpredictable lifelong disability in young adults. The treatment of patients in progressive stages remains highly challenging, alluding to our limited understanding of ...

journal_title：Journal of internal medicine

authors： Kular L,Jagodic M

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Epidemiological and clinical features of patients with COVID-19 have been reported, but none of them focused on medical staff, and few predictors of the duration of viral shedding have been reported. It is urgent to help healthcare workers prevent and recover quickly from the coronavirus disease 2019 (COVID-...

journal_title：Journal of internal medicine

authors： Liu W,Liu Y,Xu Z,Jiang T,Kang Y,Zhu G,Chen Z

更新日期：2020-12-01 00:00:00

abstract：:We describe a 57-year-old male with hypertrophic obstructive cardiomyopathy and occult blood loss. Septal alcohol ablation reduced the left ventricular outflow tract obstruction and eliminated recurrent bleeding. The case resembles Heyde's syndrome, i.e. the association between occult gastrointestinal bleeding and aor...

journal_title：Journal of internal medicine

authors： Riis Hansen P,Hassager C

更新日期：2003-04-01 00:00:00

abstract：:Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder believed to be exclusively caused by mutations in the CYP27A1 gene coding for the enzyme sterol 27-hydroxylase. Common findings in CTX are tendon xanthomas, cataracts and progressive neurological dysfunction. Here, we characterize an adult fem...

journal_title：Journal of internal medicine

authors： Hansson M,Olin M,Floren CH,von Bahr S,van't Hooft F,Meaney S,Eggertsen G,Björkhem I

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:To describe types of diabetes treatment in a total, adult population, including those on no antidiabetic medication, and to evaluate use of the defined daily doses in estimation of diabetes prevalence. DESIGN:Cross-sectional epidemiologic survey applying patient-based questionnaires and clinical examination...

journal_title：Journal of internal medicine

authors： Midthjell K,Holmen J,Bjørndal A

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To investigate influence of whole-body cooling on cyclic GMP (cGMP) in women with Raynaud's phenomenon and in healthy women. DESIGN:The study was performed as an open, parallel-group comparison between women with Raynaud's phenomenon and healthy women during the winter month of February. SETTING:The municip...

journal_title：Journal of internal medicine

authors： Leppert J,Ringqvist A,Ahlner J,Myrdal U,Sørensen S,Ringqvist I

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:To evaluate if exercise-induced ST-segment depression without typical angina pectoris is related to increases in sympatho-adrenal activity or beta-adrenoceptor sensitivity. PATIENTS:Thirteen patients (four men) aged 35-62 years with ST-segment depression during exercise but atypical symptoms and normal myoca...

journal_title：Journal of internal medicine

authors： Sundkvist GM,Hjemdahl P,Kahan T,Melcher A

更新日期：2007-02-01 00:00:00

abstract：:We describe a 22-year-old female with systemic lupus erythematosus and lymphopenia, who developed septic arthritis of the right knee with Listeria monocytogenes type 1/2 A, whilst on low-dose methotrexate (MTX). So far, septic arthritis due to this microorganism has been reported in two other patients treated with low...

journal_title：Journal of internal medicine

authors： Jansen TL,van Heereveld HA,Laan RF,Barrera P,van de Putte LB

更新日期：1998-07-01 00:00:00

abstract：:Neuroendocrine tumour of the small intestine (SI-NET), formerly known as midgut carcinoid tumour, is the most common small intestinal malignancy. The incidence is rising, with recent reports of 0.67 per 100 000 in the USA and 1.12 per 100 000 in Sweden. SI-NETs often present a challenge in terms of diagnosis and treat...

journal_title：Journal of internal medicine

authors： Stålberg P,Westin G,Thirlwell C

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:To examine to what extent traditional biomedical risk factors and social factors can predict, separately or jointly, first-ever stroke event, and to explore to what extent other risk factors might add to hypertension/elevated blood pressure as a stroke risk factor. DESIGN:An incident case-referent study. S...

journal_title：Journal of internal medicine

authors： Ohgren B,Weinehall L,Stegmayr B,Boman K,Hallmans G,Wall S

更新日期：2000-12-01 00:00:00